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Possibilities and impossibilities of magnetic nanoparticle use in the control of infectious biofilms

Journal of Materials Science & Technology 2021年第10期69卷 69-78页

作者： Kecheng Quan Zexin Zhang Yijin Ren Henk J.Busscher Henny C.van der Mei brandon w.peterson College of Chemistry Chemical Engineering and Materials ScienceSoochow UniversitySuzhou215123China University of Groningen and University Medical Center Groningen Department of Biomedical Engineering9713 AVGroningenthe Netherlands University of Groningen and University Medical Center Groningen Department of OrthodonticsHanzeplein 19713 GZGroningenthe Netherlands

Targeting of chemotherapeutics towards a tumor site by magnetic nanocarriers is considered promising in *** nanoparticles are also considered for use in infection-control as a new means to prevent antimicrobial resistance from becoming the number one cause of death by the year *** this end,magnetic nanoparticles can either be loaded with an antimicrobial for use as a delivery vehicle or modified to acquire intrinsic antimicrobial *** nanoparticles can also be used for the local generation of heat to kill infectious *** appealing for tumor-and infectioncontrol,injection in the blood circulation may yield reticuloendothelial uptake and physical obstruction in organs that yield reduced targeting *** can be prevented with suitable surface ***,precise techniques to direct magnetic nanoparticles towards a target site are *** problem of precise targeting is aggravated in infection-control due to the micrometer-size of infectious biofilms,as opposed to targeting of nanoparticles towards centimeter-sized *** review aims to identify possibilities and impossibilities of magnetic targeting of nanoparticles for *** first review targeting techniques and the spatial resolution they can achieve as well as surface-chemical modifications of magnetic nanoparticles to enhance their targeting efficiency and antimicrobial *** is concluded that targeting problems encountered in tumor-control using magnetic nanoparticles,are neglected in most studies on their potential application in *** biofilm targeting by smart,self-adaptive and pH-responsive,antimicrobial nanocarriers for instance,seems easier to achieve than magnetic *** leads to the conclusion that magnetic targeting of nanoparticles for the control of micrometer-sized infectious biofilms may be less promising than initially ***,using propulsion rather than pr

关键词： Magnetic nanoparticles Magnetic targeting Biofilm Infection Antimicrobials

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Reactive optical matter: light-induced motility in electrodynamically asymmetric nanoscale scatterers

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Light(Science & Applications) 2018年第1期7卷 26-32页

作者： Yuval Yifat Delphine Coursault Curtis w.peterson John Parker Ying Bao Stephen K.Gray Stuart A.Rice Norbert F.Scherer James Franck Institute The University of Chicago929 E.57th StreetChicagoIL 60637USA Department of Chemistry The University of Chicago929 East 57th StreetChicagoIL 60637USA Department of Physics The University of Chicago929 East 57th StreetChicagoIL 60637USA Center for Nanoscale Materials Argonne National Laboratory9700 South Cass AvenueArgonneIL 60439USA UniversitéBordeaux CNRS LOMAUMR 5798F-33400 TalenceFrance Department of Chemistry Western Washington University516 High StreetBellinghamWA 98225USA

From Newton’s third law,which is known as the principle of actio et reactio1,we expect the forces between interacting particles to be equal and opposite for closed ***,“nonreciprocal”forces can arise.2 This has been shown theoretically in the interaction between dissimilar optically trapped particles that are mediated by an external field.3 As a result,despite the incident external field not having a transverse component of momentum,the particle pair experiences a force in a direction that is transverse to the light propagation direction.3,4 In this letter,we directly measure the net nonreciprocal forces in electrodynamically interacting asymmetric nanoparticle dimers and nanoparticle structures that are illuminated by plane waves and confined to pseudo one-dimensional *** show via electrodynamic theory and simulations that interparticle interactions cause asymmetric scattering from ***,the putative nonreciprocal forces are actually a consequence of momentum *** study demonstrates that asymmetric scatterers exhibit directed motion due to the breakdown of mirror symmetry in their electrodynamic interactions with external fields.

关键词： asymmetric forces reciprocal

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铁路牵引电动机及其车轴支承轴承

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国外铁道机车与动车 1985年第10期 32-34+47页

作者： David w.peterson 朱珸

发明的背景本发明是关于铁路牵引电动机和这种电机在车轴上的支承轴承。较详尽地改进了轴支承轴承的安装,使铁路牵引电机轴承结构具有新颖的型式,包括如何安装并保持轴承于其需要的组装位置的方法。广泛使用于铁路牵引电动机的布置方法... 详细信息

发明的背景本发明是关于铁路牵引电动机和这种电机在车轴上的支承轴承。较详尽地改进了轴支承轴承的安装,使铁路牵引电机轴承结构具有新颖的型式,包括如何安装并保持轴承于其需要的组装位置的方法。广泛使用于铁路牵引电动机的布置方法,例如在电力传动内燃机车上,通常是把各台牵

关键词：支承轴承剖分轴承盖牵引电动机车轴车辆轴铁路铁道

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松针枯病

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国外林业 1986年第4期 31-32页

作者： Clenn w.peterson 郭廷举

松针枯病是松类的一种分布广泛、毁坏针叶的病害。它是由松穴褥菌(Dothist-roma pini)引起的。由于该病原菌的危害而导致松树提前落叶,尤其严重地是在大草原东部各州致使西黄松(Pinus ponderos)的造林完全失败。在中部和南部的圣诞树、... 详细信息

松针枯病是松类的一种分布广泛、毁坏针叶的病害。它是由松穴褥菌(Dothist-roma pini)引起的。由于该病原菌的危害而导致松树提前落叶,尤其严重地是在大草原东部各州致使西黄松(Pinus ponderos)的造林完全失败。在中部和南部的圣诞树、防护林带和风景林,该病原菌危害奥地利黑

关键词：针枯病美国生活史侵染针叶人工林苗圃美利坚合众国北美洲奥地利黑松松针褐斑病病原菌分生抱子西黄松美国黄松

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Glutamate triggers the expression of functional ionotropic and metabotropic glutamate receptors in mast cells

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Cellular & Molecular Immunology 2021年第10期18卷 2383-2392页

作者： Md Abdul Alim Mirjana Grujic Paul w.Ackerman Per Kristiansson Pernilla Eliasson Magnus peterson Gunnar Pejler Department of Public Health and Caring Sciences General Medicine and Preventive MedicineUppsala UniversityUppsalaSweden Department of Medical Biochemistry and Microbiology Uppsala UniversityUppsalaSweden Department of Molecular Medicine and Surgery Karolinska InstituteStockholmSweden Department of Orthopedics and Sports Medicine Linköping UniversityLinköpingSweden Academic Primary Health Care UppsalaSweden Department of Anatomy Physiology and BiochemistrySwedish University of Agricultural SciencesUppsalaSweden

Mast cells are emerging as players in the communication between peripheral nerve endings and cells of the immune ***,it is not clear the mechanism by which mast cells communicate with peripheral *** previously found that mast cells located within healing tendons can express glutamate receptors,raising the possibility that mast cells may be sensitive to glutamate *** evaluate this hypothesis,we stimulated primary mast cells with glutamate and showed that glutamate induced the profound upregulation of a panel of glutamate receptors of both the ionotropic type(NMDAR1,NMDAR2A,and NMDAR2B)and the metabotropic type(mGluR2 and mGluR7)at both the mRNA and protein *** binding of glutamate to glutamate receptors on the mast cell surface was ***,glutamate had extensive effects on gene expression in the mast cells,including the upregulation of proinflammatory components such as IL-6 and *** also induced the upregulation of transcription factors,including Egr2,Egr3 and,in particular,*** extensive induction of FosB was confirmed by immunofluorescence *** receptor antagonists abrogated the responses of the mast cells to glutamate,supporting the supposition of a functional glutamate–glutamate receptor axis in mast ***,we provide in vivo evidence supporting a functional glutamate–glutamate receptor axis in the mast cells of injured ***,these findings establish glutamate as an effector of mast cell function,thereby introducing a novel principle for how cells in the immune system can communicate with nerve cells.

关键词： Glutamate Glutamate receptors Mast cells NMDA receptors Tryptase

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Computer symbol calculation of invariants of three-manifolds obtained from trefoil knots

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Chinese Science Bulletin 1997年第2期42卷 96-102页

作者： peterson Chariya Department of Mathematics Northwestern University Evanston IL 60208 USA

FOR witten invariants, there have been many studies (see refs. [1—9]). Numerical computer calculation of some witten invariants τ_r (M) of several three-manifolds was done by Freed andGrompf and Neil. In this note, we calculate _p(M, A) by computer for all manifolds obtained by integral surgeries on a left trefoil knot, up to p≤13. The notations here are standard (see references [3, 6, 9]).

关键词： knot three-manifolds invariants.

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The marriage of coherent Raman scattering imaging and advanced computational tools

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Light(Science & Applications) 2023年第6期12卷 943-945页

作者： walker peterson Kotaro Hiramatsu Keisuke Goda Department of Chemistry The University of TokyoTokyo 113-0033Japan Research Center for Spectrochemistry The University of TokyoTokyo 113-0033Japan Department of Bioengineering University of CaliforniaLos AngelesCA 90095USA Institute of Technological Sciences Wuhan UniversityWuhanHubei 430072China LucasLand Inc.Tokyo 101-0052Japan

Coherent Raman scattering microscopy can provide high-contrast tissue and single-cell images based on the inherent molecular vibrations of the ***,conventional techniques face a three-way trade-off between Raman spectral bandwidth,imaging speed,and image *** currently challenging to address via optical design,this trade-off can be overcome via emerging computational tools such as compressive sensing and machine learning.

关键词： coherent overcome hough

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Regional-scale relationship among biological soil crusts,invasive annual grasses,and disturbance

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Ecological Processes 2013年第1期2卷 18-25页

作者： Eric B peterson Nevada Natural Hertage Program State of NevadaCarson CityNV 89701USA Curent Address Trinity River Restoration Program US Bureau of ReclamationWeavervilleCA 96093USA

Introduction:Sagebrush ecosystems in western North America are being replaced by the invasion of annual grasses,particularly Bromus *** experimental situations and in localized landscapes,prior studies have documented that biological soil crusts(biocrusts)can reduce annual grass presence and that biocrusts are highly vulnerable to physical *** conservation would benefit from verification of these patterms at scales that matter to local *** study tests if these patterns appear at a regional ***:A previously collected data set of vegetation provided sampling of biocrust cover across the Great Basin within the state of Nevada,USA Data were analyzed with non-par ametric methods including odds ratios and generalized aditive models(GAM).Results:From a data set of 608 vegetation plots within the Great Basin ecoregion,proportion of plots with high annual grass cover differed between sites with high versus low biocrust cover(p=0.0015).A negative relationship between annual grass cover and biocrust cover was confirmed with GAM(p=0.009).For a model of biocrust cover,cattle disturbance was found to be an explanatory variable(pwith high levels of cattle activity corresponding to low cover of biocrusts,and low cover of biocrusts corresponding to high cover of annual grasses.

关键词： Biological soil crusts Cryptogamic crust Microphytic crust Great basin ecoregion Sagebrush ecosystem Landscape ecology Disturbance Cattle grazing Odds ratio Generalized additive models

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高速铣削用PCD刀具的研制

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工业金刚石 2009年第3期 20-24页

作者： w.peterson P．R．Davis H．Hack 美国．梅加金刚石有限公司

高速铣削的应用在当前机械制造中越来越盛行。虽然PCD材料科学总的来说已很成熟，但高速铣削的需求促使PCD供应商不断改进与完善其产品。中粒度尺寸品级PCD材料通常用于既具有良好的耐磨性（工具寿命），同时又能保持良好的工件表面光... 详细信息

高速铣削的应用在当前机械制造中越来越盛行。虽然PCD材料科学总的来说已很成熟，但高速铣削的需求促使PCD供应商不断改进与完善其产品。中粒度尺寸品级PCD材料通常用于既具有良好的耐磨性（工具寿命），同时又能保持良好的工件表面光洁度的产品。铣削刀具典型的损坏模式是由于工件毛刺的形成而丧失切削刃的锋利度。要求是在改进表面光洁度时，减少毛刺的产生与形成。这种特有的材料性能，诸如弯曲强度和韧性的提高与改进，可通过控制金刚石粒度尺寸的分布和先进的处理工艺来达到。结果是使PCD刀具材料改进切削刃的良好性能，有更好的工件表面光洁度，而不牺牲刀具的耐磨性。这样，使最终产品的性能将在高速铣削中获得应用。

关键词： PCD刀具高速铣削表面光洁度金刚石粒度材料性能最终产品材料科学机械制造

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An integrated analysis of air pollution from US coal-fired power plants

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Geoscience Frontiers 2023年第2期14卷 204-216页

作者： Mikalai Filonchyk Michael P.peterson Faculty of Geomatics Lanzhou Jiaotong UniversityLanzhou 730070China Gansu Provincial Engineering Laboratory for National Geographic State Monitoring Lanzhou 730070China Department of Geography/Geology University of Nebraska OmahaOmahaNE 68182USA

The United States is one of the world’s leaders in electricity production,generating about 4116 billion kwh in 2021,of which coal accounted for 21.8%of the *** study applies an integrated approach using both terrestrial and satellite data to specifically examine emissions from coal-fired power plants and its spatial *** study also highlights the effectiveness of government policies to reduce *** was found that emission of pollutants from the country’s energy sector has been steadily declining,with annual emissions of sulfur dioxide(SO_(2))and nitrogen oxides(NOx)decreasing from the US electric power sector between 1990 and 2020 by 93.4%and 84.8%,respectively,and carbon dioxide(CO_(2))by 37%between 2007 and *** overall emissions from coal-fired power plants are declining,some individual plants have yet to install environmental equipment to control *** to US government data,major emitters of SO_(2),NO_(x),and CO_(2) in the US are the Martin Lake power plant in East Texas,the Labadie power plant near ***,Missouri,and the James H Miller Jr plant near Birmingham,*** study also integrates TROPOMI satellite data to detect point emissions from individual power *** the highest levels of measured pollutants were over the country’s major cities and areas of fossil fuel extraction,TROPOMI could clearly distinguish the pollution caused by power plants in more rural *** the US has made great strides in reducing emissions from coal-fired power plants,these plants still represent a major source of pollution and remain a major *** eliminating coal as a power source will be difficult with the higher power demands resulting from the transition to electric automobiles.

关键词： Coal-fired power plants Emissions TROPOMI Air pollution Sulfur dioxide Nitrogen oxides

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