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Pelvic region bone density,soft tissue mass,and injury frequency in female professional ballet dancers and soccer athletes

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sports Medicine and Health science 2021年第3期3卷 157-164页

作者： Hamed Vahedi Carter M.Taft Joshua R.Daum sherif Dabash Patrick C.McCulloch bradley s.lambert Department of Orthopedics&sports Medicine Houston Methodist HospitalHoustonTXUnited States Department of Kinesiology Rice UniversityHoustonTXUnited States

We recently observed a high prevalence of low pelvic bone mineral density(BMD)in female professional ballet *** this population is susceptible to musculoskeletal overuse injuries,we aimed to determine which regions of the pelvis may be at greatest risk compared to general population females(GENPOP)as well as professional female soccer players(sOCCER,a comparison to other elite athletes regularly subjected to high degrees of loading).Three groups of age-matched females[(GENPOP;n=38,27±1yrs),(BALLET;single com-pany,n=36,26±3yrs),(sOCCER;single NWsL■club,n=34,25±1yrs)]consented to have their BMD and body composition assessed(DEXA,GE■).In addition to soft tissue and total and regional BMD analyses,a segmental analysis of the pelvis was performed to determine site-specific BMD for the iliac fossa,iliac fossa/iliac crest/ilium combined,pubic bone,ischium,and sacrum.A mixed-model ANOVA followed by a Tukey's post-hoc test was used to compare the groups(Type-I error;α=0.05).The BALLET group had lower pelvic BMD for all measures(Avg.%Diff.=15%-27%,psOCCER group and for the ischium(Avg.%Diff.=8%;p=0.007)and sacrum(Avg.%Diff.=7%;p=0.028)compared to the GENPOP *** BALLET group had lower lean mass for all measures compared to the other groups(Avg.%Diff.=12%-18%;pssional ballet performers exhibit reduced pelvic region soft tissue and site-specific BMD not previously detected using standard DEXA *** findings highlight which pelvic regions may benefit from preventative strength training and/or nutritional interventions.

关键词： Ballet Bone Bone density Athlete Female athlete

Predicting muscular strength using demographics,skeletal dimensions,and body composition measures

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sports Medicine and Health science 2021年第1期3卷 34-39页

作者： sean T.stanelle stephen F.Crouse Tyler R.Heimdal steven E.Riechman Alexandra L.Remy bradley s.lambert Department of Health and Kinesiology Texas A&M University400 Bizzell StCollege StationTXUSA Department of Orthopedics Baylor University Medical Center3500 Gaston AveDallasTXUSA Department of Orthopedics and sports Medicine Houston Methodist Hospital6565 Fannin StHoustonTXUSA

The purpose of this study was to develop an equation to predict strength for seven common resistance training exercises using anthropometric and demographic ***-hundred forty-seven healthy adults(74 males,73 females,3512 yr,17410 cm,8819 kg)volunteered to *** composition values(regional/total)and body dimensions were assessed using dual-energy x-ray absorptiometry(DEXA).subjects underwent the following maximal strength assessments:Leg Press,Chest Press,Leg Curl,Lat Pulldown,Leg Extension,Tri-ceps Pushdown,and Biceps *** linear regression with stepwise removal was used to determine the best model to predict maximal strength for each *** predictor variables identified(psex(0=F,1=M);regional lean masses(LM,kg);fat mass(FM,kg);fat free mass(FFM,kg);percent fat(%BF);arm,leg,and trunk lengths(AL,LL,TL;cm);and shoulder width(sW,cm).Analyses were performed with and without regional measures to accommodate scenarios where DEXA is *** models presented were significant(ps producing the greatest *** indicate that maximal strength for individual resistance exercises can be reasonably estimated in adults.

关键词： strength training Exercise testing Regression equation DEXA

Recent Developments in Metallic Degradable Micromotors for Biomedical and Environmental Remediation Applications

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Nano-Micro Letters 2024年第3期16卷 1-35页

作者： sourav Dutta seungmin Noh Roger sanchis Gual Xiangzhong Chen salvador Pané bradley J.Nelson Hongsoo Choi Department of Robotics and Mechatronics Engineering Daegu Gyeongbuk Institute of Science and Technology(DGIST)Daegu 42988Republic of Korea DGIsT‑ETH Microrobotics Research Center DGISTDaegu 42988Republic of Korea Multi‑scale Robotics Lab Institute of Robotics and Intelligent SystemsETH Zurich8092 ZurichSwitzerland Institute of Optoelectronics State Key Laboratory of Photovoltaic Science and TechnologyShanghai Frontiers Science Research Base of Intelligent Optoelectronics and PerceptionFudan UniversityShanghai 200433People’s Republic of China

synthetic micromotor has gained substantial attention in biomedicine and environmental ***-based degradable micromotor composed of magnesium(Mg),zinc(Zn),and iron(Fe)have promise due to their nontoxic fuel-free propulsion,favorable biocompatibility,and safe excretion of degradation products Recent advances in degradable metallic micromotor have shown their fast movement in complex biological media,efficient cargo delivery and favorable biocompatibility.A noteworthy number of degradable metal-based micromotors employ bubble propulsion,utilizing water as fuel to generate hydrogen *** novel feature has projected degradable metallic micromotors for active in vivo drug delivery *** addition,understanding the degradation mechanism of these micromotors is also a key parameter for their design and *** propulsion efficiency and life span govern the overall performance of a degradable metallic *** we review the design and recent advancements of metallic degradable ***,we describe the controlled degradation,efficient in vivo drug delivery,and built-in acid neutralization capabilities of degradable micromotors with versatile biomedical ***,we discuss micromotors’efficacy in detecting and destroying environmental ***,we address the limitations and future research directions of degradable metallic micromotors.

关键词： Magnesium Zinc Iron Biodegradable microrobot Biomedical Environmental

Refrigerated and frozen storage impact aronia berry quality

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Food Production, Processing and Nutrition 2022年第1期4卷 13-24页

作者： Erica s.King Andrea Noll susan Glenn bradley W.Bolling Department of Food science University of Wisconsin-Madison1605 Linden Dr.MadisonWI53706USA Department of statistics Medical Sciences CenterUniversity of Wisconsin-Madison1300 University Ave Rm 1220MadisonWI53706USA

Postharvest storage of many freshly picked berries affects polyphenol and sugar content. However, little is known about the impact of refrigerated and frozen storage on aronia berry composition. Therefore, the objective of this study was to characterize how storage at 4 ± 2 °C and − 20 ± 2 °C, and temperature cycles affect aronia berry polyphenols, total solid content, pH, titratable acidity, polyphenol oxidase (PPO) activity, sugar content, acid content, color, and cell structure. Refrigerated storage reduced proanthocyanidins (21%), anthocyanins (36%), and total phenols (21%) after 12 weeks. Frozen storage increased polyphenols in the first 6 mo. of frozen storage but then decreased polyphenols at mo. 8 to levels similar to initial values. Frozen temperature cycling reduced anthocyanins 18% but did not affect total phenols or proanthocyanidins. scanning electron microscopy analysis indicated temperature cycling induced cell damage, shrinking, and fusion. This disruption led to the release of anthocyanins inside the berry tissue. PPO activity did not significantly correlate with the decrease in polyphenol content during storage. °Brix did not significantly change during refrigeration and frozen storage but did during the 12th temperature cycle. Aronia berries’ pH and titratable acidity were affected more by refrigeration than frozen and temperature storage. The pH increased by 4% during refrigeration, and titratable acidity decreased by 17% at 12 weeks. In conclusion, refrigerated storage results in a modest reduction of aronia berry polyphenols, but absolute extractable polyphenols are stable for up to 8 months of frozen storage.

关键词： Aronia berry Polyphenols storage Refrigeration sugars Acids Frozen

A novel non-invasive method for predicting bone mineral density and fracture risk using demographic and anthropometric measures

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sports Medicine and Health science 2023年第4期5卷 308-313页

作者： Justin Aflatooni steven Martin Adib Edilbi Pranav Gadangi William singer Robert Loving shreya Domakonda Nandini solanki Patrick C.McCulloch bradley lambert Orthopedic Biomechanics Research Laboratory Department of Orthopedics and Sports MedicineHouston Methodist HospitalHoustonTXUSA sydney&J.L.Huffines Institute for sports Medicine&Human Performance Department of Health and KinesiologyTexas A&M UniversityCollege StationTXUSA

Fractures are costly to treat and can significantly increase *** dual-energy x-ray absorptiometry(DEXA)is used to screen at risk people with low bone mineral density(BMD),not all areas have access to *** sought to create a readily accessible,inexpensive,high-throughput prediction tool for BMD that may identify people at risk of fracture for further *** and demographic data were collected from 492 volunteers(♂275,♀217;[44-20]years;Body Mass Index(BMI)=[27.6-6.0]kg/m^(2))in addition to total body bone mineral content(BMC,kg)and BMD measurements of the spine,pelvis,arms,legs and total ***-linear-regression with step-wise removal was used to develop a two-step prediction model for BMC followed by *** selection was determined by the highest adjusted R2,lowest error of estimate,and lowest level of variance inflation(α=0.05).Height(HTcm),age(years),sex^(m=1,f=0),%body fat(%fat),fat free mass(FFMkg),fat mass(FMkg),leg length(LLcm),shoulder width(sHWDTHcm),trunk length(TRNKLcm),and pelvis width(PWDTHcm)were observed to be significant predictors in the following two-step model(pstep1:BMC(kg)=(0.0063×HT)+(-0.0024×AGE)+(0.1712×sEX^(m=1,f=0))+(0.0314×FFM)+(0.001×FM)+(0.0089×sHWDTH)+(-0.0145×TRNKL)+(-0.0278×PWDTH)-0.5073;R^(2)=0.819,***2:Total body BMD(g/cm^(2))=(-0.0028×HT)+(-0.0437×sEX^(m=1,f=0))+(0.0008×%FAT)+(0.2970×BMC)+(-0.0023×LL)+(0.0023×sHWDTH)+(-0.0025×TRNKL)+(-0.0113×PWDTH)+1.379;R^(2)=0.89,*** models were also developed to predict leg,arm,spine,and pelvis BMD(R^(2)=0.796-0.864,ps developed here represent promising tools for identifying individuals with low BMD at risk of fracture who would benefit from further evaluation,especially in the resource or time restricted setting.

关键词： Bone Bone density Fracture Fracture risk Assessment Osteoporosis

Energy Consumption Analysis and Characterization of Aerospace Manufacturing Facilities in the United states–A step towards sustainable Development

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Energy Engineering 2023年第1期120卷 23-34页

作者： Khaled Bawaneh bradley Deken Amin Esmaeili Department of Decision science School of Business AdministrationClark Atlanta UniversityAtlantaGA30314USA Department of Engineering&Technology Southeast Missouri State UniversityCape GirardeauMO630701USA Department of Industrial and systems Engineering Kennesaw State UniversityAtlantaGA30114USA

In this study,information on energy usage in the United states(U.s.)aerospace manufacturing sector has been analyzed and then represented as energy intensities(kWh/m2)to establish benchmark data and to compare facilities of varying ***,public sources were identified and the data from these previously published sources were aggregated to determine the energy usage of aerospace manufacturing facilities within the *** this dataset,a sample of 28 buildings were selected and the energy intensity for each building was estimated from the ***,as a part of this study the energy data for three additional aerospace manufacturing facilities in the *** collected *** data was analyzed and the energy intensity(kWh/m2)for each facility was calculated and then compared with the energy intensities of the 28 buildings from the *** different indicators of energy consumption in aerospace manufacturing facilities were used as comparators to assist facility managers with determining potential energy savings and help in the decision-making *** average,aerospace manufacturing facilities in the United states spent 4 cents for each dollar of sale on *** energy intensity(kWh/m2)and the power intensity(W/m2)for each facility were calculated based on the actual facility energy *** power intensity for these facilities ranges from 34 to 134 W/*** energy intensity ranged from 232 to 949 kWh/*** found that the power intensity could be used to estimate energy consumption when the annual operating hours of the facility are *** to estimate the energy-related carbon dioxide emissions.

关键词： Aerospace facilities energy consumption life cycle information in aerospace manufacturing buildings sustainable manufacturing buildings

COVID-19 Mortality and Vaccine Coverage——Hong Kong special Administrative Region,China,January 6,2022-March 21,2022

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China CDC weekly 2022年第14期4卷 288-292页

作者： Dallas J.smith Avi J.Hakim Gabriel M.Leung Wenbo Xu WWilliam schluter Ryan T.Novak Barbara Marston bradley s.Hersh CDC COVID-19 Response International Task Force Atlanta Epidemic Intelligence service CDC Li Ka shing Faculty of Medicine University of Hong KongHong Kong Special Administrative RegionChina National Institute for Viral Disease Control and Prevention Chinese Center for Disease Control and PreventionBeijingChina CDC China BeijingChina

summary What is already known about this topic?COVID-19 vaccines are important tools to protect populations from severe disease and *** is added by this report?Among persons aged≥60 years in Hong Kong,49%,had received≥2 doses of a COVID-19 vaccine,and vaccination coverage declined with *** January-March 2022,reported COVID-19-associated deaths rose rapidly in Hong *** these deaths,96%occurred in persons aged≥60 years;within this age group,the risk for death was 20 times lower among those who were fully vaccinated compared with those who were unvaccinated.

关键词： doses COV deaths

Targeting the m6A mRNA demethylase FTO suppresses vascular endothelial growth factor release and choroidal neovascularization

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signal Transduction and Targeted Therapy 2023年第3期8卷 905-907页

作者： shao-bin Wang Yosuke Nagasaka Dionne Argyle Ayami Nagasaka Praveen Yerramothu bradley DGelfand Jayakrishna Ambati Center for Advanced Vision science University of Virginia School of MedicineCharlottesvilleVAUSA Department of Ophthalmology University of Virginia School of MedicineCharlottesvilleVAUSA Department of Biomedical Engineering University of Virginia School of MedicineCharlottesvilleVAUSA Department of Pathology University of Virginia School of MedicineCharlottesvilleVAUSA Department of Microbiology Immunologyand Cancer BiologyUniversity of Virginia School of MedicineCharlottesvilleVAUSA

Dear Editor,Vascular endothelial growth factor-A(VEGFA,also known as VEGF)is a critical angiogenic factor that regulates the physiological and pathological blood vessel growth.1 Increased abundance of VEGF in the eye underlies many forms of aberrant ocular angiogenesis and resultant vision loss,including in neovascular age-related macular degeneration(nvAMD),proliferative diabetic retinopathy(PDR).

关键词： degeneration ocular release

Integrated vision-based system for efficient,semi-automated control of a robotic manipulator

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International Journal of Intelligent Computing and Cybernetics 2014年第3期7卷 253-266页

作者： Hairong Jiang Juan P.Wachs bradley s.Duerstock school of Industrial Engineering Purdue UniversityWest LafayetteIndianaUSA Weldon school of Biomedical Engineering School of Industrial EngineeringPurdue UniversityWest LafayetteIndianaUSA

Purpose–The purpose of this paper is to develop an integrated,computer vision-based system to operate a commercial wheelchair-mounted robotic manipulator(WMRM).In addition,a gesture recognition interface system was developed specially for individuals with upper-level spinal cord injuries including object tracking and face recognition to function as an efficient,hands-free WMRM ***/methodology/approach–Two Kinects cameras were used synergistically to perform a variety of simple object retrieval *** camera was used to interpret the hand gestures and locate the operator’s face for object positioning,and then send those as commands to control the *** other sensor was used to automatically recognize different daily living objects selected by the *** object recognition module employing the speeded Up Robust Features algorithm was implemented and recognition results were sent as a commands for“coarse positioning”of the robotic arm near the selected *** face detection was provided as a shortcut enabling the positing of the objects close by the subject’s ***–The gesture recognition interface incorporated hand detection,tracking and recognition algorithms,and yielded a recognition accuracy of 97.5 percent for an eight-gesture ***’completion time were conducted to compare manual(gestures only)and semi-manual(gestures,automatic face detection,and object recognition)WMRM control *** use of automatic face and object detection significantly reduced the completion times for retrieving a variety of daily living ***/value–Integration of three computer vision modules were used to construct an effective and hand-free interface for individuals with upper-limb mobility impairments to control a WMRM.

关键词： Gesture recognition Object recognition spinal cord injuries Wheelchair-mounted robotic arm