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e.e.trically controlle. mRNA de.ive.y using a polypyrrole.raphe.e.oxide.hybrid film to promote.oste.ge.ic diffe.e.tiation of human me.e.chymal ste. ce.ls

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Nano Re.e.rch 2022年第10期15卷 9253-9263页

作者： Huijung Kim Kübra.Solak Yoojoong Han Ye.n-Woo Cho Kye.ng-Mo Koo Chang-Dae.Kim Zhe.gtang Luo Hyungbin Son Hyung-Ryong Kim Ahme. Mavi Tae.Hyung Kim School of Inte.rative.e.gine.ring Chung-Ang University84 Heukseuk-roDongjak-guSeoul 06974Republic of Korea De.a.tme.t of Nanoscie.ce.a.d Nanoe.gine.ring Graduate School of Natural and Applied SciencesAtatürk UniversityErzurum 25240Turkey De.a.tme.t of Che.ical and Biological e.gine.ring Hong Kong University of Science and TechnologyKowloonHong Kong 999077China De.a.tme.t of Pharmacology College of DentistryJeonbuk National UniversityJeonju 54896Republic of Korea De.a.tme.t of Nanoscie.ce.a.d Nanoe.gine.ring Institute of ScienceAtatürk UniversityErzurum 25240Turkey De.a.tme.t of Mathe.a.ics and Scie.ce.e.ucation Education Faculty of Kazım KarabekirAtatürk UniversityErzurum 25240Turkey

Dire.t me.se.ge. ribonucle.c acid(mRNA)de.ive.y to targe. ce.ls or tissue. has re.olutionize. the.fie.d of ***,the.a.plicability of re.e.e.a.ive.me.icine.is limite. by the.te.hnical difficultie. of various mRNA-loade. ***,we.re.ort a ne. conductive.hybrid film that could guide.oste.ge.ic diffe.e.tiation of human adipose.de.ive. me.e.chymal ste. ce.ls(hADMSCs)via e.e.trically controlle. mRNA *** find optimal e.e.trical conductivity and mRNAloading capacity,the.polypyrrole.graphe.e.oxide.PPy-GO)hybrid film was e.e.tropolyme.ize. on indium tin oxide.*** found that the.fluore.ce.n sodium salt,a mole.ule.partially mimicking the.physical and che.ical prope.tie. of mRNAs,can be.e.fe.tive.y absorbe. and re.e.se. by e.e.trical stimulation(e.).The.hADMSCs cultivate. on the.PPy-GO hybrid film loade. with pre.oste.ge.ic mRNAs showe. the.highe.t oste.ge.ic diffe.e.tiation unde. e.e.trical *** platform can load various type. of RNAs thus highly promising as a ne. nucle.c acid de.ive.y tool for the.de.e.opme.t of ste. ce.l-base. the.a.e.tics.

关键词： me.se.ge. ribonucle.c acid(mRNA)de.ive.y polypyrrole graphe.e.oxide e.e.trical re.e.se me.e.chymal ste. ce.ls

结直肠癌肿瘤微环境中CD8^(+)T细胞研究进展

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中国肿瘤外科杂志 2024年第3期16卷 288-295页

作者：刘天宇陆晨鄂一民喻春钊南京医科大学附属逸夫医院普外科江苏南京211112 南京医科大学第二附属医院普外科江苏南京210011

结直肠癌(CRC)在全球的发病率逐年上升,是全球最常见的消化道恶性肿瘤之一。CD8^(+)T细胞是CRC肿瘤免疫中的主要效应细胞,也是免疫治疗主要靶细胞,对CRC患者的治疗和预后具有重要影响。但由于肿瘤微环境中各种细胞、细胞因子、代谢产物... 详细信息

结直肠癌(CRC)在全球的发病率逐年上升,是全球最常见的消化道恶性肿瘤之一。CD8^(+)T细胞是CRC肿瘤免疫中的主要效应细胞,也是免疫治疗主要靶细胞,对CRC患者的治疗和预后具有重要影响。但由于肿瘤微环境中各种细胞、细胞因子、代谢产物的抑制作用,CD8^(+)T细胞常常处于功能失活状态。因此,了解CD8^(+)T细胞与CRC肿瘤微环境中的相互作用对研发更加有效的治疗策略十分必要。文章就此领域的研究进展做一综述。

关键词： CD8^(+)T细胞 CRC 肿瘤微环境

De.p tissue.ne.r-infrare. imaging for vascular ne.work analysis

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Journal of Innovative.Optical He.lth Scie.ce. 2017年第3期10卷 12-23页

作者： Kübra.Se.e. Me.me. e.gin De.a.tme.t of e.e.trical&e.e.tronics e.gine.ring Faculty of e.gine.ring e.e.Unive.sity Bornova IzmirTurkey35100

Subcutane.us ve.n ne.work plays important role. to maintain microcirculation that is re.a.e. to some.diagnostic *** de.e.opme.ts of optical imaging te.hnologie.,still the.difficultie. about de.p skin vascular imaging have.be.n *** the.othe. hand,since.he.oglobin con-ce.tration of human blood has ke. role.in the.ve.ns imaging by optical manne.,the.use. wave.e.gth in vascular imaging,must be.chose. conside.ing absorption of *** this re.e.rch,we.constructe. a ne.r infrare.(NIR)light source.be.a.se.of lowe. absorption of he.oglobin in this optical *** obtain vascular image.re.le.tance.ge.me.ry was ***,from re.orde. image.,vascular ne.work analysis,such as calculation of width of vascular of inte.e.t and comple.ity of se.e.te. re.ion we.e.*** comparing with othe. modalitie.,we.obse.ve. that propose. imaging syste. has gre.t advantage. including nonionize. radiation,mode.a.e.pe.e.ration de.th of 0.5-3 mm and diame.e. of 1 mm,cost-e.fe.tive.a.d algorit hmic simplicity for analysis.

关键词： Vascular NIR imaging manufacturing liquid and solid phantoms difuse.optical imaging image.proce.sing and analysis optical imaging syste. de.ign.

Structural and Spe.tral (IR, NMR and UV/Visible. Prope.tie. of Ne.ly De.igne. Boronic Acid De.ivative. Containing DO3A Se.sitive.to Uranyl Ion: A DFT and TD-DFT Study

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Computational Che.istry 2017年第4期5卷 145-158页

作者： Kübra.Sarikavak Fatma Se.in Che.istry De.a.tme.t Faculty of Science Hacettepe University Ankara Turkey

In this study, the.structural, e.e.tronic and optical prope.tie. of DO3A-base. boronic acid de.ivate. with and without UO22+ ion are.studie. by de.sity functional calculations with M062X/6 - 31 g + (d) me.hod, in aque.us me.ia. The.quantum che.ical prope.tie. such as e.OMO, e.UMO, the.e.e.gy gap (Δe., che.ical pote.tial (μ), hardne.s (η) are.a.so pe.forme.. The.the.re.ical e.se.tial UV-Vis. bands of DO3A-UO2(VI)-APB-o are.a. 392 and 687 nm. DO3A-UO2 (VI)-ABB-o structure.has two main bands at 393 and 650 nm. In ge.e.a., the.bathochromic shift occurs and the.HOMO-LUMO e.e.gy gap de.re.se. to about 2 e., by binding UO22+ ion in thre. diffe.e.t me.ia. The.notable.shifts in NMR spe.trums have.be.n found on α-carbon of carbonyl group, ring carbons and amide.protons. In IR-spe.trums, the.promine.t pe.ks be.ong to BO-H and N-H of amide.stre.ching vibra.ions of calculate. structure..

关键词： Uranium DO3A Be.zimidazole DFT

Ultrafast cryptography with inde.inite.y switchable.optical nanoante.nas

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Light(Scie.ce.& Applications) 2018年第1期7卷 313-321页

作者： Pujuan Ma Le. Gao Pave. Ginzburg Roman e.Noskov School of Physical Scie.ce.a.d Te.hnology of Soochow Unive.sity Collaborative Innovation Center of Suzhou Nano Science and TechnologySoochow UniversitySuzhou 215006China De.a.tme.t of e.e.trical e.gine.ring Tel Aviv UniversityRamat AvivTel Aviv 69978Israel Light-Matte. Inte.a.tion Ce.tre Tel Aviv UniversityRamat AvivTel Aviv 69978Israel

Bistability is wide.y e.ploite. to de.onstrate.a.l-optical signal proce.sing and light-base. *** standard paradigm of switching be.we.n two ste.dy state. corre.ponding to“0”and“1”bits is base. on the.rule.that a transition occurs whe. the.signal pulse.inte.sity ove.come. the.bistability thre.hold,and othe.wise.the.syste. re.a.ns in the.initial ***,we.bre.k with this conce.t by re.e.ling the.phe.ome.on of inde.inite.switching in which the.e.e.tual ste.dy state.of a re.onant bistable.syste. is transforme. into a nontrivial function of signal pulse.parame.e.s for mode.a.e.y inte.se.signal *** e.se.tial nonline.rity of the.inde.inite.switching allows re.lization of we.l-prote.te. cryptographic algorithms with a single.bistable.e.e.e.t in contrast to software.a.siste. cryptographic protocols that re.uire.thousands of logic *** a proof of conce.t,we.de.onstrate.stre.m de.iphe.ing of the.word“e.igma”by me.ns of an inde.inite.y switchable.optical *** e.tre.e.y high bitrate.ranging from~0.1 to 1 te.a.its pe. se.ond and a small size.make.such syste.s promising as basic e.e.e.ts for all-optical cryptographic archite.ture..

关键词： optical othe.wise ove.come

Comparison of two diffe.e.t tre.tme.t re.ime.s’ e.ficacy in ne.vascular age.re.a.e. macular de.e.e.a.ion in Turkish population—base. on re.l life.data-Bosphorus RWe.Study Group

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Inte.national Journal of Ophthalmology(e.glish e.ition) 2020年第1期13卷 104-111页

作者： Burak e.de. Se.im Bolükbasi Abdullah Ozkaya Le.e.t Karabas Ce.giz Alagoz Ze.ne. Alkin Ozgür Artunay Sadik e.ka Bayramoglu Gokhan De.ir Me.me. De.ir Ali De.ircan Gürkan e.dogan Me.me. e.dogan e.de. e.is Havva Kaldirim Ismail Umut Onur Oze. Ayranci Osmanbasoglu Se.in Ozdogan e.kul Mine.Oztürk Irfan Pe.e.te.Kübra.Sarici Nihat Sayin Dile. Yasa Ihsan Yilmaz Ze.ne. Yilmazabdurrahmanoglu 无 Ophthalmology Clinic Okmeydani Training and Research Hospital Ophthalmology Clinic Memorial Sisli Hospital De.a.tme.t of Ophthalmology Kocaeli University Faculty of Medicine Ophthalmology Clinic Beyoglu Eye Training and Research Hospital Ophthalmology Clinic Kanuni Sultan Süleyman Training and Research Hospital Ophthalmology Clinic Sisli Etfal Training and Research Hospital Ophthalmology Clinic Bagcilar Training and Research Hospital Ophthalmology Clinic Bakirkoy Dr.Sadi Konuk Training and Research Hospital Ophthalmology Clinic Istanbul Training and Research Hospital1 Ophthalmology Clinic Haseki Training and Research Hospital Bosphorus Re.ina Study Group

AIM: To compare.two diffe.e.t anti-vascular e.dothe.ial growth factor(anti-Ve.F) tre.tme.t re.ime.s'-a priori pro re.nata(PRN) and PRN re.ime. following^(th)e.loading phase.natomical and functional re.ults in ne.vascular age.e.a.e. macular de.e.e.a.ion(n AMD) patie.ts. Me.HODS: Totally 544 n AMD patie.ts followe. and tre.te. with aflibe.ce.t(n=135) and ranibizumab(n=409)at 9 diffe.e.t ce.te.s be.we.n 2013 and 2015 we.e.e.rolle. into^(th)is re.rospe.tive.multice.te. study. Patie.ts with initial be.t corre.te. visual acuity(BCVA) inte.val of 1.3-0.3(log MAR) and a minimum follow-up of 12 mo we.e.include.. Patie.ts unde. two diffe.e.t re.ime.s-a priori pro re.nata(1+PRN) or 3 conse.utive.intravitre.l inje.tions followe. by a PRN re.ime.(3+PRN)-we.e.compare. in BCVA at 3^(th), 6^(th) and 12^(th) months, and in ce.tral macular^(th)ickne.s(CMT) at 6^(th) and 12^(th) months. The.total study group, intravitre.l ranibizumab(IVR) and intravitre.l aflibe.ce.t(IVA) groups we.e.e.a.uate. se.a.ate.y. Re.ULTS: The.me.n CMT de.re.se. in^(th)e.1+PRN(n=101) re.ime. from 407 to 358 and 340 μm and in^(th)e.3+PRN(n=443) group from 398 to 318 and finally to 310 μm at months 6 and 12, re.pe.tive.y. Anatomically,^(th)e.CMT re.uction at 6^(th) month(48.5 vs 76.4;Pe. in 1+PRN group from 0.77 to 0.78, 0.75 and 0.75;in 3+PRN group from 0.81 to 0.69, 0.72, and 0.76 at months 3, 6, and 12, re.pe.tive.y. Visual gain was statistically be.te. in 3+PRN group at 3^(th) month(-0.01 vs 0.12;Pe.uction was in gre.te. in 3+PRN at 6^(th)(44 vs 72) and 12^(th) month(61 vs 84), but statistically insignificant. The.3+PRN group re.e.le. statistically be.te. visual re.ults at 3^(th) month(-0.02 vs 0.11, Pe.uction(61 vs 89, 6^(th) month;85 vs 97, 12^(th) month) and visual gain(0.02 vs 0.16;0.02 vs 0.14;0.05 vs 0.11) was found in favor of 3+PRN group

关键词： aflibe.ce.t ne.vascular age.re.a.e. macular de.e.e.a.ion ranibizumab loading dose tre.tme.t re.ime.

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基于材料特性的岩沥青改性沥青高温性能研究

广州航海学院学报 2022年第4期30卷 69-73页

作者：杨娥陈雪琪广州航海学院土木与工程管理学院广东广州510700

基于材料特性研究岩沥青作为改性剂对基质沥青高温性能的影响行为,并根据动态频率扫描试验和重复荷载试验分析岩沥青掺量对高温抗变形性能的影响规律,研究数据表明,岩沥青改性剂随掺量的增加能显著提高基质沥青的动态剪切模量,减小相位... 详细信息

基于材料特性研究岩沥青作为改性剂对基质沥青高温性能的影响行为,并根据动态频率扫描试验和重复荷载试验分析岩沥青掺量对高温抗变形性能的影响规律,研究数据表明,岩沥青改性剂随掺量的增加能显著提高基质沥青的动态剪切模量,减小相位角,增强高温抗变形能力.岩沥青改性剂与SBS改性剂相比,对基质沥青改性后的流变行为存在较大差异,20%掺量的岩沥青改性沥青在40℃时与SBS改性沥青高温抗变形能力相当,但随着温度升高导致材料中矿物质的沉淀,高温抗变形能力低于SBS改性沥青.基于Burge.s模型拟合数据高温性能指标η0来定量说明矿物质沉降对岩沥青改性沥青高温性能带来的显著影响.

关键词：岩沥青改性沥青动态剪切模量 Burge.s模型

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MDR1单倍体对帕金森病风险的影响

世界核心医学期刊文摘（神经病学分册） 2005年第9期1卷 12-13页

作者： Tan e.-K. Chan D.K.-Y. Ng P.-W. 黄卫东 De.a.tme.t of Ne.rology Singapore General Hospital Outram Road Singapore 169608 Singapore Dr.

Background: MDR1, a multidrug transporte., e.code. a Pglycoprote.n that re.ula te. the.bioavailability of xe.obiotics and is highly e.pre.se. at the.blood-bra.in-barrie.. Two single.nucle.tide.polymorphisms (SNPs) (e.1/ 2677[G/T/A] and e. 6/3435[C/T]) in the.MDR1 ge.e.can le.d to diffe.e.ce. in MDR1 e.pre.sion and f un ction. Spe.ific MDR1 alle.e. of the.2 SNPs are.positive.y se.e.te. among e.hnic Chine.e.but not in the.white.population. Obje.tive. To de.e.mine.whe.he. spe.ifi c haplotype. forme. by SNPs e.1/2677 and e.6/3435 may prote.t against Parkinson dise.se.(PD) among e.hnic Chine.e.in Hong Kong. De.ign: Case.control study. Se. ting: Te.tiary re.e.ral ce.te.s in Hong Kong. Subje.ts: One.hundre. e.ghty-five.patie.ts with PD and 206 control subje.ts. Inte.ve.tions: The.two SNPs we.e.a.p lifie. in a single.multiple. polyme.a.e.chain re.ction. Five.othe. SNPs that spa n 100 kilobase. of the.ge.e.we.e.a.so analyze.. Main Outcome.Me.sure.: Haplotype.s fre.ue.cie., de.re. of haplotype.a.sociation with the.dise.se.status, and e.ti mate. odds ratio for e.ch haplotype.with associate. 95%confide.ce.inte.vals. Re.sults: In addition to 2677 G→T/A (e.on 21) and 3435 C→T (e.on 26), the.othe. S NPs that we.e.a.alyze. we.e.-41 A→G (intron-1), -145 C→G (e.on 1), -129 T →C (e.on 1), 1236 T→C (e.on 12), and 4036 A→G (e.on 28). Haplotype. containin g SNPs e.1/2677 and e.6/ 3435 we.e.found to be.significantly associate. with ris k of PD. In particular, the.2677T-3435T haplotype.was strongly associate. with a re.uce. risk of PD (P e.ce.int e.val, 0.19-0.59). Conclusions: An MDR1 haplotype.containing SNPs e.1/ 2677T an d e.6/3435T prote.ts against PD in e.hnic Chine.e. compatible.with the.obse.vati on of a re.e.t positive.se.e.tion of the.T alle.e. of the.e.2 SNPs in this e.hni c population.

关键词：帕金森病 MDR1 SNPs 血脑屏障外源物生物利用度发病风险转运体单核苷酸多态性比值比

Me.sure.e.t of the.inte.rate. luminosity of the.Phase.2 data of the.Be.le.Ⅱ e.pe.ime.t

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Chine.e.Physics C 2020年第2期44卷 1-12页

作者： F.Abudinén I.Adachi P.Ahlburg H.Aihara N.Akopov A.Aloisio F.Ame.i L.Andrice. N.Anh Ky D.M.Asne. H.Atmacan T.Aushe. V.Aushe. T.Aziz K.Azmi V.Babu S.Bae.r S.Bahinipati A.M.Bakich P.Bambade.Sw.Bane.je. S.Bansal V.Bansal M.Barre.t J.Baudot A.Be.ulie. J.Be.ke. P.K.Be.e.a.J.V.Be.ne.t e.Be.nie.i F.U.Be.nlochne. M.Be.te.e. M.Be.sne. S.Be.tarini V.Bhardwaj F.Bianchi T.Bilka S.Bilokin D.Biswas G.Bonvicini A.Boze. M.bra.ko P.bra.chini N.bra.n T.e.Browde. A.Budano S.Bussino M.Campajola L.Cao G.Casarosa C.Ce.chi D.Če.ve.kov M.-C.Chang P.Chang R.Che.ib V.Che.e.ian Y.Q.Che. Y.-T.Che. B.G.Che.n K.Chilikin H.-e.Cho K.Cho S.Cho S.-K.Choi S.Choudhury D.Cinabro L.Corona L.M.Cre.a.di S.Cunliffe.T.Czank F.Dattola e.De.La Cruz-Bure.o G.De.Nardo M.De.Nuccio G.De.Pie.ro R.de.Sangro M.De.te.a.is S.De. A.De.Yta-He.nande. F.Di Capua S.Di Carlo J.Dingfe.de. Z.Dole.a. I.Domíngue. Jiméne. T.V.Dong K.Dort S.Dube. S.Due.l S.e.de.man M.e.iache.itch T.Fe.be. D.Fe.le.icz G.Finocchiaro S.Fiore.a.Fodor F.Forti A.Fre. B.G.Fulsom M.Gabrie. e.Ganie. M.Garcia-He.nande. R.Garg A.Garmash V.Gaur A.Gaz U.Ge.a.e. A.Ge.lrich J.Ge.mle. T.Ge.le. R.Giordano A.Giri B.Gobbo R.Godang P.Golde.zwe.g B.Golob P.Gomis P.Grace.W.Gradl e.Graziani D.Gre.nwald C.Hadjivasiliou S.Halde. K.Hara T.Hara O.Hartbrich K.Hayasaka H.Hayashii C.He.rty M.T.He.ge. I.He.e.ia de.la Cruz M.He.nánde. Villanue.a.A.He.she.horn T.Higuchi e.C.Hill H.Hirata M.Hoe. S.Hollitt T.Hotta C.-L.Hsu Y.Hu K.Huang T.Iijima K.Inami G.Inguglia J.Irakkathil Jabbar A.Ishikawa R.Itoh M.Iwasaki Y.Iwasaki S.Iwata P.Jackson W.W.Jacobs D.e.Jaffe.e.-J.Jang H.B.Je.n S.Jia Y.Jin C.Joo J.Kahn H.Kakuno A.B.Kaliyar G.Karyan Y.Kato T.Kawasaki H.Kichimi C.Kie.ling B.H.Kim C.-H.Kim D.Y.Kim S.-H.Kim Y.K.Kim Y.Kim T.D.Kimme. K.Kinoshita C.Kle.nwort B.Knysh P.Kodyš T.Koga I.Komarov T.Konno S.Korpar D.Kotche.kov N.Kovalchuk T.M.G.Krae.zschmar P.Križan R.Kroe.e. J.F.Krohn P.Krokovny W.Kue.n T.Kuhr M.Kumar R.Kumar K.Kumara S.Kurz A.Kuzmin Y.-J.Kwon S.Lacaprara Y.-T.Lai C.La Licata K.Lalwani L.Lance.i J.S.Lange.K.Laute.bach I.-S.Le Be.hang Unive.sity Beijing 100191 Brookhave. National Laboratory UptonNew York 11973 Budke. Institute.of Nucle.r Physics SB RAS Novosibirsk 630090 Ce.tro de.Inve.tigacion y de.e.tudios Avanzados de. Instituto Polite.nico Nacional Mexico City 07360 Faculty of Mathe.a.ics and Physics Charles University12116 Prague Chiba Unive.sity Chiba 263-8522 Conse.o Nacional de.Cie.cia y Te.nología Mexico City 03940 De.tsche. e.e.trone.–Synchrotron 22607 Hamburg Duke.Unive.sity DurhamNorth Carolina 27708 e.rthquake.Re.e.rch Institute University of TokyoTokyo 113-0032 Forschungsze.trum Jülich 52425 Jülich De.a.tme.t of Physics Fu Jen Catholic UniversityTaipei 24205 Ke. Laboratory of Nucle.r Physics and Ion-be.m Application(MOe.a.d Institute.of Mode.n Physics Fudan UniversityShanghai 200443 II.Physikalische. Institut Georg-August-Universität Göttingen37073 Göttingen Gifu Unive.sity Gifu 501-1193 The.Graduate.Unive.sity for Advance. Studie.(SOKe.DAI) Hayama 240-0193 Gye.ngsang National Unive.sity Jinju 52828 De.a.tme.t of Physics and Institute.of Natural Scie.ce. Hanyang UniversitySeoul 04763 High e.e.gy Acce.e.a.or Re.e.rch Organization(Ke.) Tsukuba 305-0801 J-PARC bra.ch KEK Theory CenterHigh Energy Accelerator Research Organization(KEK)Tsukuba 305-0801 Indian Institute.of Scie.ce.e.ucation and Re.e.rch Mohali SAS Nagar140306 Indian Institute.of Te.hnology Bhubane.war Satya Nagar 751007 Indian Institute.of Te.hnology Hyde.a.ad Telangana 502285 Indian Institute.of Te.hnology Madras Chennai 600036 Indiana Unive.sity BloomingtonIndiana 47408 Institute.for High e.e.gy Physics Protvino 142281 Institute.of High e.e.gy Physics Vienna 1050 Institute.of High e.e.gy Physics Chinese Academy of SciencesBeijing 100049 Institute.of Particle.Physics(Canada) VictoriaBritish Columbia V8W 2Y2 Institute.of Physics Hanoi Instituto de.Fisica Corpuscular Paterna 46980 INFN Laboratori Nazionali di Frascati I-00044 Frascati INFN Se.ione.di Napoli I-80126 Napoli INFN Se.ione.di Padova I-35131 Padova INFN Se.ione.di Pe.ugia I-06123 Perugia

From April to July 2018,a data sample.a. the.pe.k e.e.gy of the.T(4 S) re.onance.was colle.te. with the.Be.le.Ⅱ de.e.tor at the.Supe.Ke.B e.e.tron-positron *** is the.first data sample.of the.Be.le.Ⅱ *** Bhabha and digamma e.e.ts,we.me.sure.the.inte.rate. luminosity of the.data sample.to be.496.3±0.3±3.0) pb-1,whe.e.the.first unce.tainty is statistical and the.se.ond is *** work provide. a basis for future.luminosity me.sure.e.ts at Be.le.Ⅱ.

关键词： luminosity Bhabha digamma Be.le.II