检索结果-南通市图书馆

Effects of Dietary Changes on the Gut microbiota of Cynops orientalis

Asian Herpetological research 2024年第2期15卷 63-72页

作者： Yuting WANG Yuning XIE Siyu WU Wenwen ZHANG Xiner CHENG Zixuan LI Fangfei HAN Jiayi SHI Yingying SHI Zhirong HE Chunna ZHANG Yixin JIANG na ZHAO Jiaqi LI Supen WANG College of Life Sciences Anhui Normal UniversityWuhu 241000AnhuiChina nanjing Institute of Environmental Sciences Ministry of Ecology and Environment of ChinaNanjing 210042JiangsuChina School of Ecology and Environment Anhui Normal UniversityWuhu 241002AnhuiChina Key Laboratory of Zoological Systematics and Evolution Institute of ZoologyChinese Academy of SciencesBeijing 100101China

The gut microbiota plays a pivotal role in the maintenance of health for amphibians,and it has been fully recognized,but the effectiveness of various influencing factors has not yet been fully *** this association should be considered while the amphibian order Caudata is facing a severe situation of population decline and extinction,there is little understanding of the association between diets and the diversity of gut microbiota in the amphibian order ***,we conducted an extensive analysis of the gut microbiota of Cynops orientalis fed different diets using functional prediction and 16S rrna amplicon sequencing ***,we found that wild individuals had greater gut microbial diversity and richness in comparison to captive ***,we identified the bacterial taxa associated with diets and observed differences in the relative abundance of gut microbiota among people on various ***,we have a predictive comprehension of the selection and adaptative significance of shared core ASVs in the gut microbiota in maintaining the healthy survival of *** in a large-scale spatiotemporal *** study emphasizes how diets alter the gut microbiota of Caudata and offers fresh perspectives on the conservation and captive management of species in Caudata.

关键词： 16S rrna Caudata core microbiota diet gut microbiota

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

非单频声场中耦合双泡振动特性研究

引用

云南大学学报（自然科学版） 2024年第1期46卷 67-73页

作者：李娜宁夏医科大学医学信息与工程学院宁夏银川750004

利用Keller-miksis方程,计算了初始半径分别为2、5μm的耦合气泡在非单频声场中气泡半径、次Bjerknes力的变化规律.计算结果表明,非单频驱动声场中耦合双泡的半径、次Bjerknes力与驱动声压幅值、声压幅值之比、驱动频率有关.当声压幅值... 详细信息

利用Keller-miksis方程,计算了初始半径分别为2、5μm的耦合气泡在非单频声场中气泡半径、次Bjerknes力的变化规律.计算结果表明,非单频驱动声场中耦合双泡的半径、次Bjerknes力与驱动声压幅值、声压幅值之比、驱动频率有关.当声压幅值比、驱动频率一定时,驱动声压越大,最大膨胀半径越大、次Bjerknes力越大;驱动声压、驱动频率一定时,声压幅值比越大,最大膨胀半径越大、次Bjerknes力越大;当驱动声压的振幅、声压幅值比一定时,驱动频率越大,最大膨胀半径越小、次Bjerknes力越小.

关键词：非单频驱动耦合双泡最大膨胀半径次Bjerknes力

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

女性生殖道畸形的诊治和生育新观念

引用

中华妇产科杂志 2024年第5期59卷 343-345页

作者：朱兰陈娜中国医学科学院北京协和医院妇产科、国家妇产疾病临床医学研究中心、疑难重症及罕见病全国重点实验室北京100730

本文简要介绍两类罕少见的女性生殖道畸形疾病近年来的诊治和生育进展。强调对不合并功能性子宫内膜的mayer-rokitansky-Küster-Hauser综合征(mrKH综合征)患者,非手术治疗(顶压法)为一线治疗,国内医师应更新治疗观念;少数合并功能性子... 详细信息

本文简要介绍两类罕少见的女性生殖道畸形疾病近年来的诊治和生育进展。强调对不合并功能性子宫内膜的mayer-rokitansky-Küster-Hauser综合征(mrKH综合征)患者,非手术治疗(顶压法)为一线治疗,国内医师应更新治疗观念;少数合并功能性子宫内膜的mrKH综合征患者,明确诊断后应及时行腹腔镜双侧始基子宫切除术,是否同时行阴道重建术需与患方充分沟通后决策。目前,代孕和子宫移植技术均可实现mrKH综合征患者的生育需求,在法律允许的前提下,代孕对患者的创伤和经济成本等方面优于子宫移植。目前,先天性子宫颈发育异常患者保留生育功能的子宫颈管通道重建术式有贯通术和吻合术两类。对于有足够子宫颈组织的患者,可考虑行贯通术。吻合或贯通术后保持生殖道的通畅性是治疗成功的关键。保留生育功能的重建手术后患者可获得生育的希望,但总体妊娠率仍较低,需妇科、产科和生殖医学专家全程通力合作以改善该类患者的生育结局。

关键词：保留生育功能 mrKH综合征子宫颈管代孕子宫移植通畅性生育结局顶压法

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The Uptake and Distribution Evidence of nano-and microplastics in vivo after a Single High Dose of Oral Exposure

引用

Biomedical and Environmental Sciences 2024年第1期37卷 31-41页

作者： HONG Tao SUN Wei DENG Yuan LYU Jian Da JIN Cui Hong BAI Ying Long na Jun ZHANG rui GAO Yuan PAN Guo Wei YANG Zuo Sen YAN Ling Jun research Center for Universal Health School of Public HealthChina Medical UniversityShenyang 110122LiaoningChina Department of Pain management Shengjing Hospital of China Medical UniversityShenyang 110004LiaoningChina Department of Toxicology School of Public HealthChina Medical UniversityShenyang 110122LiaoningChina Department of maternal and Child Health School of Public HealthChina Medical UniversityShenyang 110122LiaoningChina Institute of Preventive medicine China Medical UniversityShenyang 110122LiaoningChina Institute of Chronic Diseases Liaoning Provincial Center for Disease Control and PreventionShenyang 110000LiaoningChina

Objective Tissue uptake and distribution of nano-/microplastics was studied at a single high dose by gavage in *** Fluorescent microspheres(100 nm,3μm,and 10μm)were given once at a dose of 200 mg/(kg∙body weight).The fluorescence intensity(FI)in observed organs was measured using the IVIS Spectrum at 0.5,1,2,and 4 h after *** was performed to corroborate these *** In the 100 nm group,the FI of the stomach and small intestine were highest at 0.5 h,and the FI of the large intestine,excrement,lung,kidney,liver,and skeletal muscles were highest at 4 h compared with the control group(Pm group,the FI only increased in the lung at 2 h(Pm group,the FI increased in the large intestine and excrement at 2 h,and in the kidney at 4 h(Presence of nano-/microplastics in tissues was further verified by *** peak time of nanoplastic absorption in blood was *** nanoplastics translocated rapidly to observed organs/tissues through blood circulation;however,only small amounts of mPs could penetrate the organs.

关键词： microplastics nanoplastics IVIS Spectrum small-animal imaging system Tissue distribution Blood

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

N6-methyladenosine methylation regulates the tumor microenvironment of Epstein-Barr virus-associated gastric cancer

引用

World Journal of Gastrointestinal Oncology 2024年第6期16卷 2555-2570页

作者： Yu Zhang Fang Zhou ming-Yu Zhang Li-na Feng Jia-Lun Guan ruo-nan Dong Yu-Jie Huang Su-Hong Xia Jia-Zhi Liao Kai Zhao Department of Gastroenterology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030Hubei ProvinceChina Institute of Liver and Gastrointestinal Diseases Hubei Key Laboratory of Hepato-Pancreato-Biliary DiseasesTongji Hospital of Tongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030Hubei ProvinceChina Department of Pharmacy Wuhan Fourth HospitalWuhan 430030Hubei ProvinceChina

BACKGrOUND N6-methyladenosine(m6A)methylation modification exists in Epstein-Barr virus(EBV)primary infection,latency,and lytic *** also modifies EBV latent genes and lytic ***-associated gastric cancer(EBVaGC)is a distinctive molecular subtype of *** hypothesized EBV and m6A methylation regulators interact with each other in EBVaGC to differentiate it from other types of *** To investigate the mechanisms of m6A methylation regulators in EBVaGC to determine the differentiating factors from other types of *** First,The Cancer Gene Atlas and Gene Expression Omnibus databases were used to analyze the expression pattern of m6A methylation regulators between EBVaGC and EBV-negative GC(EBVnGC).Second,we identified Gene Ontology(GO)and Kyoto Encyclopedia of Genes and Genomes(KEGG)functional enrichment of m6A-related differentially expressed *** quantified the relative abundance of immune cells and inflammatory factors in the tumor microenvironment(TmE).Finally,cell counting kit-8 cell proliferation test,transwell test,and flow cytometry were used to verify the effect of insulin-like growth factor binding protein 1(IGFBP1)in EBVaGC cell *** m6A methylation regulators were involved in the occurrence and development of *** with EBVnGC,the expression levels of m6A methylation regulators Wilms tumor 1-associated protein,rna binding motif protein 15B,CBL proto-oncogene like 1,leucine rich pentatricopeptide repeat containing,heterogeneous nuclear ribonucleoprotein A2B1,IGFBP1,and insulin-like growth factor 2 binding protein 1 were significantly downregulated in EBVaGC(Prall survival rate of EBVaGC patients with a lower expression level of IGFBP1 was significantly higher(P=0.046).GO and KEGG functional enrichment analyses showed that the immunity pathways were significantly activated and rich in immune cell infiltration in *** with EBVnGC,the infiltration of activated CD4+T cells,activated CD8+T cel

关键词： N6-methyladenosine methylation Tumor microenvironment Epstein-Barr virus Gastric cancer Insulin-like growth factor binding protein 1

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Triceps skinfold thickness trajectories and the risk of all-cause mortality:A prospective cohort study

引用

World Journal of Clinical Cases 2024年第15期12卷 2568-2577页

作者： na Yang Li-Yun He Zi-Yi Li Yu-Cheng Yang Fan Ping Ling-Ling Xu Wei Li Hua-Bing Zhang Yu-Xiu Li Department of Endocrinology Key Laboratory of Endocrinology of National Health CommissionPeking Union Medical College HospitalChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100730China

BACKGrOUND The measurement of triceps skinfold(TSF)thickness serves as a noninvasive metric for evaluating subcutaneous fat *** its clinical utility,the TSF thickness trajectories and their correlation with overall mortality have not been thoroughly *** To explore TSF thickness trajectories of Chinese adults and to examine their associations with all-cause *** This study encompassed a cohort of 14747 adults sourced from the China Health and Nutrition *** class trajectory modeling was employed to identify distinct trajectories of TSF *** were classified into subgroups reflective of their respective TSF thickness *** utilized multivariate Cox regression analyses and mediation examinations to explore the link between TSF thickness trajectory and overall mortality,including contributory *** Upon adjustment for multiple confounding factors,we discerned that males in the‘Class 2:Thin-stable’and‘Class 3:Thin-moderate’TSF thickness trajectories exhibited a markedly reduced risk of mortality from all causes in comparison to the‘Class 1:Extremely thin’*** the mediation analyses,the Geriatric Nutritional risk Index was found to be a partial intermediary in the relationship between TSF thickness trajectories and *** females,a lower TSF thickness pattern was significantly predictive of elevated all-cause mortality risk exclusively within the non-elderly *** In males and non-elderly females,lower TSF thickness trajectories are significantly predictive of heightened mortality risk,independent of single-point TSF thickness,body mass index,and waist circumference.

关键词： Triceps skinfold thickness Trajectory All-cause mortality Body mass index Geriatric Nutritional risk Index

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Pathogenicity and transcriptomic profiling reveals immunology molecular hallmarks after CA10 virus infection

引用

Animal models and Experimental medicine 2024年第05期 717-731页

作者： Wanjun Peng Jing Wu Binbin Zhao Lihong Zhang Xin Chen Xiaohui Wei na rong Yunlin Han Jiangning Liu NHC Key Laboratory of Human Disease Comparative medicine Beijing Key Laboratory for Animal Models of Emerging and Remerging Infectious Diseases Institute of Laboratory Animal Science Chinese Academy of Medical Sciences and Comparative Medicine Center Peking Union Medical College

Background: Hand, foot and mouth disease(HFmD) is a common infectious disease caused by viral infection by a variety of enteroviruses, with coxsackievirus A 10(CA10) having become more prevalent in recent ***: In this study, models of CA10 infection were established in 7-day-old Institute of Cancer research(ICr) mice by intraperitoneal injection to analyze the pathogenicity of the virus. rna sequencing analysis was used to screen the differentially expressed genes(DEGs) after CA10 infection. Coxsackievirus A 16(CA16) and enterovirus 71(EV71) infections were also compared with ***: After CA10 virus infection, the mice showed paralysis of the hind limbs at 3 days post infection and weight loss at 5 days post infection. We observed viral replication in various tissues and severe inflammatory cell infiltration in skeletal muscle. The rna-sequencing analysis showed that the DEGs in blood, muscle,thymus and spleen showed heterogeneity after CA10 infection and the most upregulated DEGs in muscle were enriched in immune-related pathways. Compared with CA16 and EV71 infection, CA10 may have an inhibitory effect on T helper(Th) cell differentiation and cell growth. Additionally, the common DEGs in the three viruses were most enriched in the immune system response, including the Toll-l ike receptor pathway and the nucleotide-binding and oligomerization domain(NOD)-l ike ***: Our findings revealed a group of genes that coordinate in response to CA10 infection, which increases our understanding of the pathological mechanism of HFmD.

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

地铁区间运行列车火灾早期烟气特性研究

引用

铁道工程学报 2024年第8期41卷 111-115页

作者：江崇旭那艳玲中国铁路设计集团有限公司天津300142

研究目的:探明区间运行列车火灾早期烟气特性是火灾快速精准探测、定位、预警的基础。本文通过建立运行列车火灾数值仿真计算模型,计算120 km/h区间运行列车车顶、车底、车头、车中、车尾6个工况火灾早期不同时刻空气温度、烟气浓度的... 详细信息

研究目的:探明区间运行列车火灾早期烟气特性是火灾快速精准探测、定位、预警的基础。本文通过建立运行列车火灾数值仿真计算模型,计算120 km/h区间运行列车车顶、车底、车头、车中、车尾6个工况火灾早期不同时刻空气温度、烟气浓度的变化规律。研究结论:(1)地铁区间运行列车火灾烟气呈非对称分布,烟气主要向车尾传播蔓延,火点前方1 m处已检测不到明显温度、烟气浓度变化;(2)测点温度和烟气浓度实时监测值与火源间距呈负相关规律,距火点相同距离处车底火灾空气温度较车顶火灾高100%,烟气浓度高500%;(3)相对速度差对绝对温度比影响较小,在5 m/s和10 m/s速度差下,距火点1 m处绝对温度比均大于0.45,在距火点3 m处绝对温度比均大于0.75;(4)本研究成果可为地铁防火标准完善和防排烟设计提供参考。

关键词：地铁区间运动列车火灾早期烟气特性

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

布达拉宫地震危险性分析

引用

振动与冲击 2024年第15期43卷 95-104页

作者：崔玥杨娜北京交通大学土木建筑工程学院北京100044

布达拉宫是我国著名的世界文化遗产,其所在地区活动断层发育、大地震频发。开展可靠的地震危险性评估,可为该研究区内以布达拉宫为首的藏式古建筑抗震保护提供依据。该文对比传统地震危险性分析方法的不足,采用基于多锁固段破裂理论的... 详细信息

布达拉宫是我国著名的世界文化遗产,其所在地区活动断层发育、大地震频发。开展可靠的地震危险性评估,可为该研究区内以布达拉宫为首的藏式古建筑抗震保护提供依据。该文对比传统地震危险性分析方法的不足,采用基于多锁固段破裂理论的地震物理预测方法,提出了地震危险性评估的系统流程。并根据地震烈度和地震动参数衰减关系,考虑场地自身条件,进行了布达拉宫所在区域的地震危险性评估。研究结果表明,该研究区位于林芝地震区,未来100年内该研究区的地震危险性主要为林芝地震区的下一次m_(S)8.5主震或m_(S)7.8标志性地震;发震断层位于亚东-谷露断层中段附近的纳木错东南岸断裂,震中位置为30.3°N,90.1°E附近;布达拉宫建筑群坐落在基岩,不考虑山体场地放大作用,结构接地端地震作用与基岩相当。研究结论为开展布达拉宫建筑群结构抗震研究提供理论依据。

关键词：布达拉宫锁固段衰减关系标志性地震场地条件

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

旗鼓相当还是相形失色?——境内并购与跨境并购的生产效率比较研究

引用

管理评论 2024年第8期36卷 65-78页

作者：李娜陈奉先山东财经大学金融学院济南250014 首都经济贸易大学金融学院北京100070

提高全要素生产率是实现经济高质量发展的动力源泉。本文通过构建两国古诺双头垄断模型,比较了企业无并购、境内并购和跨境并购时的全要素生产率差异,并以2008—2020年中国上市公司的1229起境内并购和111起跨境并购事件为研究对象,采用... 详细信息

提高全要素生产率是实现经济高质量发展的动力源泉。本文通过构建两国古诺双头垄断模型,比较了企业无并购、境内并购和跨境并购时的全要素生产率差异,并以2008—2020年中国上市公司的1229起境内并购和111起跨境并购事件为研究对象,采用倾向得分匹配和多时点双重差分法实证检验并购行为对企业全要素生产率的影响与作用机制。研究发现:(1)境内并购和跨境并购均显著提升了企业的全要素生产率,且跨境并购的提升作用更为明显。当企业为非国有企业、高新技术企业、受融资约束程度低的企业,且两国政治关系良好、东道国制度质量高时,上述现象表现尤为显著。(2)进一步研究发现,跨境并购通过创新协同效应、管理协同效应对企业全要素生产率的提升作用强于境内并购。不同的是,境内并购的市场垄断效应对全要素生产率起到负面作用,而跨境并购的市场垄断效应并不显著。三种效应叠加最终使得境内并购的全要素生产率提升效应明显弱于跨境并购。在贸易纷争不断的背景下,鼓励我国企业“走出去”整合外部资源,同时积极营造公平竞争的市场环境助力企业整合内部资源,这对实现全要素生产率提升、经济高质量增长具有重要意义。

关键词：境内并购跨境并购全要素生产率 PSm-DID

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：