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玢岩型铁矿床尾矿中磷、稀土战略性矿产资源调查与综合利用研究:以安徽凹山矿田为例

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矿床地质 2024年第3期43卷 707-710页

作者：段超张长青王丛林杨秉阳刘冠男邓杰邓善芝康博文侯可军谢京佳刘欢秦燕自然资源部成矿作用与资源评价重点实验室中国地质科学院矿产资源研究所北京100037 安徽马钢矿业资源集团南山矿业有限公司安徽马鞍山243033 中国地质科学院矿产综合利用研究所四川成都610041

玢岩型铁矿床是铁矿石的重要来源,其除了赋存巨量铁矿资源外,还以产出大量磷灰石为特征,伴生大量的磷、稀土、钒等资源。20世纪,矿业开发大多只回收主要矿种铁,对伴生资源的评价和综合利用较少。文章以凹山玢岩型铁矿田尾矿库为研究对象... 详细信息

玢岩型铁矿床是铁矿石的重要来源,其除了赋存巨量铁矿资源外,还以产出大量磷灰石为特征,伴生大量的磷、稀土、钒等资源。20世纪,矿业开发大多只回收主要矿种铁,对伴生资源的评价和综合利用较少。文章以凹山玢岩型铁矿田尾矿库为研究对象,开展伴生资源调查评价和综合利用示范研究。通过系统钻探采样、矿物组合分析、元素赋存状态和综合利用实验等研究,文章揭示出尾矿库中经济矿物为磷灰石,可综合利用资源为磷和稀土,并估算尾矿库中磷储量超过115万t、稀土5万t,社会和经济效益巨大,可作为范例进一步研究并推广应用。

关键词：磷稀土尾矿调查评价综合利用玢岩型铁矿床

视神经鞘直径与眼球横径比值变化量对俯卧位脊柱手术患者眼部并发症的预测价值

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中华解剖与临床杂志 2024年第5期29卷 311-315页

作者：高兴悦凌云志谢亚琼章迪王竹张凯刘婉钰李博文陈珂张雍兴蚌埠医科大学第一附属医院麻醉科蚌埠233004 蚌埠医科大学研究生院蚌埠233030 蚌埠医科大学临床医学院蚌埠233030

目的探讨视神经鞘直径(ONSD)与眼球横径(ETD)比值(ONSD/ETD)的变化量对俯卧位脊柱手术患者眼部并发症的预测价值。方法病例对照研究。纳入2022年10月—2023年6月蚌埠医科大学第一附属医院行择期俯卧位脊柱手术患者62例,其中男17例、女45... 详细信息

目的探讨视神经鞘直径(ONSD)与眼球横径(ETD)比值(ONSD/ETD)的变化量对俯卧位脊柱手术患者眼部并发症的预测价值。方法病例对照研究。纳入2022年10月—2023年6月蚌埠医科大学第一附属医院行择期俯卧位脊柱手术患者62例,其中男17例、女45例,年龄50~75(63.7±6.0)岁。根据脊柱手术后是否发生眼部并发症分为2组:眼部并发症组17例,其中男5例、女12例,年龄53~74(65.1±7.5)岁;眼部正常组45例,其中男12例,女33例,年龄52~75(63.2±5.4)岁。对2组患者的性别、年龄、合并高血压/糖尿病、俯卧位时长、体质量指数、ONSD/ETD变化量、失血量、术中输液量等进行单因素分析,将差异有统计学意义(P<0.05)的指标进行多因素logistic回归分析,采用受试者操作特征(ROC)曲线检验ONSD/ETD变化量对脊柱术后发生眼部并发症的预测效能。结果单因素分析结果显示,俯卧位时长、ONSD/ETD变化量是脊柱术后眼部并发症的影响因素,差异有统计学意义(Z=2.612、t=4.011,P值均<0.05)。多因素logistic回归分析显示,ONSD/ETD变化量是脊柱术后眼部并发症的独立危险因素[OR(95%CI)为2.159(1.142~4.083)]。ROC曲线显示,ONSD/ETD变化量的最佳截断值为0.514,曲线下面积(95%CI)为0.783(0.644~0.923),灵敏度0.688,特异度0.826。结论ONSD/ETD变化量是脊柱手术后眼部并发症的独立危险因素,对脊柱手术后眼部并发症有一定的预测价值。

关键词：俯卧位脊柱手术视神经鞘直径眼球横径眼部并发症影响因素

急性Stanford A型主动脉夹层合并器官灌注不良的研究进展

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中国胸心血管外科临床杂志 2024年第8期31卷 1235-1241页

作者：张博文顿耀军刘雁翔高浩昱任杰王露辰周桑榆谢明鑫孙晓刚中国医学科学院、北京协和医学院、国家心血管病中心、阜外医院血管外科中心北京100037

急性Stanford A型主动脉夹层治疗一直以来极具挑战性,器官灌注不良综合征是急性主动脉夹层常见的严重并发症,可导致患者脏器缺血坏死引起内环境紊乱,提高手术死亡率,并且影响患者预后。近些年来,各国学者对主动脉夹层合并器官灌注不良... 详细信息

急性Stanford A型主动脉夹层治疗一直以来极具挑战性,器官灌注不良综合征是急性主动脉夹层常见的严重并发症,可导致患者脏器缺血坏死引起内环境紊乱,提高手术死亡率,并且影响患者预后。近些年来,各国学者对主动脉夹层合并器官灌注不良做了许多研究工作,探索了发生机制,提出了新的分型,创新了治疗方案,但是各个中心对其处理策略仍缺乏一致性意见。因此,本文主要就急性Stanford A型主动脉夹层合并器官灌注不良的发生机制、分型、诊治策略和预后方面的相关进展进行综述。

关键词：急性Stanford A型主动脉夹层外科治疗灌注不良综述

Analysis of inverse synthetic aperture radar imaging in the presence of time-varying plasma sheath

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Plasma Science and Technology 2022年第3期24卷 19-32页

作者： Yaocong xie Xiaoping LI Fangfang SHEN bowen BAI Yanming LIU Xuyang CHEN Lei SHI School of Aerospace Science and Technology Xidian UniversityXi'an 710071People's Republic of China

The plasma sheath can induce radar signal modulation,causing not only ineffective target detection,but also defocusing in inverse synthetic aperture radar(ISAR)*** this paper,through establishing radar echo models of the reentry object enveloped with time-varying plasma sheath,we simulated the defocusing of ISAR images in typical *** results suggested that the ISAR defocusing is caused by false scatterings,upon which the false scatterings’formation mechanism and distribution property are analyzed and *** range of false scattering correlates with the electron density fluctuation *** combined value of the electron density fluctuation and the pulse repetition frequency jointly determines the Doppler of false *** measurement metrics including peak signal-to-noise ratio and structural similarity are used to evaluate the influence of ISAR imaging.

关键词： ISAR imaging plasma sheath time-varying transmission line matrix defocusing

微创小切口普通椎弓根螺钉固定治疗对胸腰椎骨折患者血清CK、HMGB-1及TNF-α水平的影响

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分子诊断与治疗杂志 2024年第6期16卷 1028-1031页

作者：谢德胜简国坚陈小林王博文刘好源厦门大学附属成功医院(中国人民解放军陆军第七十三集团军医院)骨科福建厦门361000

目的探讨微创小切口普通椎弓根螺钉固定治疗对胸腰椎骨折患者血清肌酸激酶(CK)、高迁移率族蚩白B-1(HMGB-1)及肿瘤坏死因子-α(TNF-α)水平的影响。方法对2022年2月至2023年2月期间厦门大学附属成功医院收治的124例胸腰椎骨折患者行... 详细信息

目的探讨微创小切口普通椎弓根螺钉固定治疗对胸腰椎骨折患者血清肌酸激酶(CK)、高迁移率族蚩白B-1(HMGB-1)及肿瘤坏死因子-α(TNF-α)水平的影响。方法对2022年2月至2023年2月期间厦门大学附属成功医院收治的124例胸腰椎骨折患者行回顾性研究,按照手术方案不同分为对照组(n=60,切开椎弓根螺钉内固定治疗)与试验组(n=64,微创小切口普通椎弓根螺钉固定治疗)。比较两组患者围手术期指标、治疗前后炎性因子[CK、HMGB-1及TNF-α]变化、 Oswestry功能障碍指数问卷(ODI)、视觉模拟评分法(VAS)评分及术后并发症情况。结果与对照组比较,试验组手术总时长、透视时间、术中出血量、术后住院天数及骨折愈合时长更短,术中出血量更少,差异有统计学意义(P<0.05);治疗后1 d、3 d,两组CK、HMGB-1及TNF-α水平均明显上升,治疗7 d出现下降,且试验组上述指标水平低于对照组,差异有统计学意义(P<0.05);治疗后6个月,两组ODI评分、VAS评分均明显降低,且试验组上述评分均低于对照组,差异有统计学意义(P<0.05);试验组的并发症率(3.12%)比对照组(15.00%)低,差异有统计学意义(P<0.05)。结论微创小切口普通椎弓根螺钉固定治疗可显著降低胸腰椎骨折患者CK、HMGB-1及TNF-α水平,促进患者术后恢复速度。

关键词：微创小切口普通椎弓根螺钉固定术胸腰椎骨折 CK HMGB-1 TNF-α

减氮配施有机粪肥对土壤理化性质及玉米产量的影响

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黑龙江农业科学 2024年第6期 25-30页

作者：李博文谢威王平李忠志孙祥海张明聪黑龙江八一农垦大学农学院黑龙江大庆163319 北大荒农垦集团有限公司宝泉岭分公司农业生产部黑龙江鹤岗154100

为提高畜禽粪便等农业废弃物在农业生产过程中循环利用效率,改善土壤肥力,促进作物增产增收,于2022年春季在宝泉岭农场开展有机粪肥还田减施氮肥试验,设置生育期不施化肥(CK)、当地常规施肥(FFP)、优化施肥(OPT)、有机粪肥替代15%N(OPT... 详细信息

为提高畜禽粪便等农业废弃物在农业生产过程中循环利用效率,改善土壤肥力,促进作物增产增收,于2022年春季在宝泉岭农场开展有机粪肥还田减施氮肥试验,设置生育期不施化肥(CK)、当地常规施肥(FFP)、优化施肥(OPT)、有机粪肥替代15%N(OPT-1)、有机粪肥替代30%N(OPT-2)5个处理,研究有机粪肥和减施氮肥对土壤理化性质和玉米产量的影响。结果表明,在拔节期,与常规施肥(FFP)相比,有机粪肥替代30%氮肥处理(OPT-2)土壤有机质和速效钾含量分别显著提高14.28%和6.71%,有机粪肥替代15%氮肥处理(OPT-1)土壤有机质和速效钾含量分别显著提高10.20%和11.32%;与优化施肥处理(OPT)相比,OPT-2处理土壤有机质含量显著提高7.63%,OPT-1处理土壤速效钾含量显著提高7.01%。在成熟期,与FFP处理相比,OPT-2处理土壤有机质、碱解氮和速效钾含量分别提高15.60%、9.64%和6.83%,玉米产量显著提高8.46%,OPT-1处理土壤有机质、碱解氮和速效钾含量分别显著提高10.33%、5.26%和10.62%,玉米产量显著提高5.14%;与OPT处理相比,OPT-2处理土壤有机质、碱解氮含量分别显著提高11.09%和8.93%,OPT-1处理土壤有机质、碱解氮和速效钾含量分别显著提高6.03%、4.57%和5.80%。综合分析,施用有机粪肥可以改善土壤理化性质,提高玉米产量,改善籽粒品质,其中,30%有机粪肥替代氮肥(OPT-2)施用效果最优。

关键词：禽畜粪便有机肥有机无机配施土壤养分含量

Stretchable Parylene-C electrodes enabled by serpentine structures on arbitrary elastomers by silicone rubber adhesive

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Journal of Materiomics 2020年第2期6卷 330-338页

作者： bowen Ji Zhaoqian xie Wen Hong Chunpeng Jiang Zhejun Guo Longchun Wang Xiaolin Wang Bin Yang Jingquan Liu National Key Laboratory of Science and Technology on Micro/Nano Fabrication Department of Micro/Nano ElectronicsShanghai Jiao Tong UniversityShanghai200240China Department of Engineering Mechanics Dalian University of TechnologyDalian116024China

The delicate serpentine structures are widely used in high-performance stretchable electronics over the past *** metal interconnects encapsulated in biocompatible polymer Parylene-C film is a superior choice for long-term implantation in vivo,especially as neural interface to acquire electrophysiological signals or apply electrical *** avoid the physical contact damages from the neural tissues such as the brain or peripheral nerves,serpentine interconnects are utilized as stretchable electrodes and usually bonded to the soft elastomer *** adhesion strength between the serpentine interconnects and the elastomer substrate becomes a considerable issue to ensure reliability and structural *** this paper,the stretchable Parylene-C electrodes can be transfer printed onto arbitrary elastomer substrates by a thin layer of silicone rubber adhesive with low modulus for electrocorticogram(ECoG)*** simulation of serpentine structures consisting of same periodic arcs and different straight segments is investigated by uniaxial ***,the elastic stretchability of serpentine electrodes is further studied by simulation and *** 5000 repetitive stretching cycles,the electrochemical impedance of microelectrodes remains in steady *** results prove that the silicone rubber adhesive facilitates the interfacial bonding in the structure of stretchable electrodes as the compliant and reliable neural interface.

关键词： Stretchable Parylene-C electrodes Serpentine structure Arbitrary elastomers Silicone rubber adhesive

High throughput direct writing of a mesoscale binary optical element by femtosecond long focal depth beams

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Light(Advanced Manufacturing) 2023年第4期4卷 130-139页

作者： Yue Yang Erse Jia Xinyu Ma Chen xie bowen Liu Yanfeng Li Minglie Hu Ultrafast Laser Laboratory Key Laboratory of Opto-electronic Information Technical Science of Ministry of EducationSchool of Precision Instruments and Opto-electronics EngineeringTianjin UniversityTianjin 300072China

Bessel beams have multiple applications owing to their propagation-invariant properties,including particle trapping,optical coherence tomography,and material ***,traditional Bessel-beam shaping techniques require bulky components,which limits the development of miniaturized optical systems for integration with other ***,we report a novel femtosecond laser direct writing strategy for fabricating mesoscale(from submicrometer to subcentimeter)binary optical elements with microscale *** strategy utilizes femtosecond beams with a long focal depth to increase throughput while reducing the constraints on critical sample *** a demonstration,we manufactured and characterized a 2.2 mm diameter binary *** experimentally measured quasi-Bessel beam intensity distribution and the numerical results were remarkably consistent,demonstrating a suitable tradeoff between the overall size,efficiency,and structural ***,a compact Bessel lens containing binary axicons was constructed and successfully used for femtosecond laser mask-less ablation of periodic grating-type surface plasmon polariton excitation *** demonstrated approach shows significant potential for fabricating customizable integrated optical components.

关键词： Femtosecond laser direct writing Spatial light modulator Binary optical element Mesoscale Bessel beam

Combination therapy to overcome ferroptosis resistance by biomimetic self-assembly nano-prodrug

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Asian Journal of Pharmaceutical Sciences 2023年第5期18卷 99-111页

作者： Yong Huang Yi Lin bowen Li Fu Zhang Chenyue Zhan Xin xie Zhuo Yao Chongzhi Wu Yuan Ping Jianliang Shen School of Ophthalmology&Optometry School of Biomedical EngineeringWenzhou Medical UniversityWenzhou 325035China College of Pharmaceutical Sciences Zhejiang UniversityHangzhou 310058China Guangdong Provincial Key Laboratory of Research and Development of Natural Drugs and School of PharmacyGuangdong Medical UniversityDongguan 523808China Wenzhou Institute University of Chinese Academy of SciencesWenzhou 325000China

Ferroptosis has emerged as a potent form of no-apoptotic cell death that offers a promising alternative to avoid the chemoresistance of apoptotic pathways and serves as a vulnerability of ***,we have constructed a biomimetic self-assembly nano-prodrug system that enables the co-delivery of gefitinib(Gefi),ferrocene(Fc)and dihydroartemisinin(DHA)for the combined therapy of both ferroptosis and *** the tumor microenvironment,this nano-prodrug is able to disassemble and trigger drug release under high levels of ***,the released DHA can downregulate GPX4 level for the enhancement of intracellular ferroptosis from Fc,further executing tumor cell death with concomitant chemotherapy by *** importantly,this nano-prodrug provides highly homologous targeting ability by coating related cell membranes and exhibits outstanding inhibition of tumor growth and metastasis,as well as no noticeable side-effects during *** simple small molecular self-assembled nano-prodrug provides a new reasonably designed modality for ferroptosis-combined chemotherapy.

关键词： Self-assembly nano-prodrug Ferroptosis Apoptosis Combination therapy