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Understanding the hydrocarbon-generation potential on jurassic coal-measure source rocks in the Junggar Basin: From the perspective of hydrogen-rich molecular structure

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Petroleum Science 2024年第5期21卷 2969-2983页

作者： Tian-Chen Ge Xiang-Chun Chang Guan-Long Zhang Jun-Jian Zhang Rui-Chao Guo Wei-Zheng Gao Ling-Yu Zhao Shang-Bin Wang Jia-Qi duan College of Earth Science and Engineering Shandong University of Science and TechnologyQingdao266590ShandongChina Laboratory for Marine Mineral Resources Qingdao Marine Science and Technology CenterQingdao266237ShandongChina Research Institute of Petroleum Exploration and Development Shengli Oil CompanySinopecDongying257001ShandongChina School of Geology and Mining Engineering Xinjiang UniversityUrumqi830017XinjiangChina

The Jurassic coal-measure source rocks in the Junggar Basin have drawn considerable attention in recent years. In our hydrocarbon thermal simulation experiments of these rocks, we found that the dark mudstone evaluated as good source rock, had a much lower hydrocarbon generation capacity than the coal and carbonaceous mudstone, evaluated as poor source rock. Based on this background, we performed Fourier transform infrared spectroscopy(FTIR) and combined the results of semi-open thermal simulation experiments to explore the association between the molecular structure and hydrocarbon production capacity, with the aim of obtaining a new understanding of hydrocarbon potential of Jurassic coal-measure source rocks from the perspective of molecular structure. The results indicate that coals exhibit lower condensation of aromatic structures and higher relative abundance of aliphatic structures with a higher degree of branched chaining than mudstones and carbonaceous mudstones. Apparent aromaticity(f_a), aromatic abundance parameter I, and degree of condensation(DOC) are negatively correlated with organic matter abundance. The aliphatic structural parameter H demonstrates a substantial positive correlation with organic matter abundance. Furthermore, aliphatic relative abundance factor A is associated with the type of organic matter;the better is the type of the organic matter, the larger is the A value. The combination of the molecular structures with the thermal simulation results shows that the aliphatic hydrogen enrichment of selected carbonaceous mudstone is similar to that of coal. However, the relative abundance of the aliphatic group of it is high, and the DOC of the aromatic structure is low, making the hydrocarbon generation base stronger and easier to crack. Thus, the hydrocarbon generation capacity of carbonaceous mudstone is slightly higher than that of coal. Mudstone has low H and I values, and the DOC is high, indicating that its hydrocarbon base is low, so i

关键词： Coal-measure source rock Hydrocarbon potential Macromolecular structure Semi-open system pyrolysis Junggar basin

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拼焊板V形自由弯曲精确回弹控制技术研究

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机械工程学报 2014年第10期50卷 40-47页

作者：段永川官英平先进锻压成形技术与科学教育部重点实验室(燕山大学) 秦皇岛066004

在平截面和平面弯曲等假设条件下,建立拼焊板V形可适于小曲率自由弯曲回弹的解析预测模型,所建立的回弹预测模型将成形过程分段研究,即区分为贴模阶段和未贴模阶段。分别根据贴模态和未贴模态拼焊板弯矩分布特点,构建两种状态下的曲率... 详细信息

在平截面和平面弯曲等假设条件下,建立拼焊板V形可适于小曲率自由弯曲回弹的解析预测模型,所建立的回弹预测模型将成形过程分段研究,即区分为贴模阶段和未贴模阶段。分别根据贴模态和未贴模态拼焊板弯矩分布特点,构建两种状态下的曲率分布方程。在自由弯曲卸载分析阶段,引入两母板间相互作用的弯矩,同时考虑弹性模量随塑性变形变化的影响,基于单一母板求解拼焊板母板回弹后的弯曲角。基于2D单应矩阵变换法实现拼焊板回弹后端面弯曲角的在线测量。针对板料中材料参数的波动性问题,基于正交表构建最佳行程预测的神经网络模型的训练样本。根据软硬件接口基于LabVIEW软件平台开发可在线学习的拼焊板V形自由弯曲回弹控制系统软件。设定目标回弹后弯曲角分别为140°和100°时,跟踪在线成形试验结果,成形第5周期最大点误差可分别达到1.42%和2.01%。

关键词：拼焊板自由弯曲回弹控制

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Seed amplification assay of nasal swab extracts for accurate and non-invasive molecular diagnosis of neurodegenerative diseases

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Translational Neurodegeneration 2023年第1期12卷 681-690页

作者： Suying duan Jing Yang Zheqing Cui Jiaqi Li Honglin Zheng Taiqi Zhao Yanpeng Yuan Yutao Liu Lu Zhao Yangyang Wang Haiyang Luo Yuming Xu Department of Neurology The First Affiliated Hospital of Zhengzhou Uni-versityZhengzhou UniversityZhengzhouChina Department of Rhinology The First Affiliated Hospital of Zhengzhou UniversityZhengzhouChina The Academy of Medical Sciences of Zhengzhou University Zhengzhou UniversityZhengzhouChina Henan Key Laboratory of Cerebrovascular Diseases The First Affiliated Hospital of Zhengzhou UniversityZhengzhou UniversityZhengzhouChina Institute of Neuroscience Zhengzhou UniversityZhengzhouChina

Nasal swabs are non-invasive testing methods for detecting diseases by collecting samples from the nasal cavity or *** is regarded as an early sign of coronavirus disease 2019(COVID-19),and nasal swabs are the gold standard for the *** nasal swabs,severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)nucleic acids can be cyclically amplified and detected using real-time reverse transcriptase-polymerase chain reaction after ***,olfactory dysfunction precedes the onset of typical clinical manifestations by several years in prion diseases and other neurodegenerative diseases,such as Alzheimer’s disease,Parkinson’s disease,dementia with Lewy bodies,and multiple system *** neurodegenerative diseases,nasal swab tests are currently being explored using seed amplification assay(SAA)of pathogenic misfolded proteins,such as prion,α-synuclein,and *** misfolded proteins can serve as templates for the conformational change of other copies from the native form into the same misfolded form in a prion-like *** for misfolded prion-like proteins from nasal swab extracts has been developed,conceptually analogous to PCR,showing high sensitivity and specificity for molecular diagnosis of degenerative diseases even in the prodromal *** amplification assay of nasal swab extracts is an attractive and feasible method for accurate and non-invasive detection of trace amount of pathogenic substances for screening and diagnosis of neurodegenerative disease.

关键词： Nasal swab Seed amplification assay Prion disease Amyloid Neurodegenerative diseases

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外源长链脂肪酸对酿酒酵母脂肪酸代谢、生长繁殖、抗逆性及香气合成的影响

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中国食品学报 2017年第7期17卷 165-174页

作者：段亮亮燕国梁段长青陕西中医药大学公共卫生学院陕西咸阳712046 中国农业大学食品科学与营养工程学院葡萄与葡萄酒研究中心北京100083

发酵基质中长链脂肪酸物质(C_(14)-C_(18))是影响酿酒酵母生长代谢的重要营养成分。本文重点阐述外源长链脂肪酸对酿酒酵母脂肪酸代谢、生长繁殖,抗逆性和产生香气化合物的影响,以及在葡萄酿酒产业的应用,以期为葡萄酒工业化生产提供理... 详细信息

发酵基质中长链脂肪酸物质(C_(14)-C_(18))是影响酿酒酵母生长代谢的重要营养成分。本文重点阐述外源长链脂肪酸对酿酒酵母脂肪酸代谢、生长繁殖,抗逆性和产生香气化合物的影响,以及在葡萄酿酒产业的应用,以期为葡萄酒工业化生产提供理论指导。

关键词：脂肪酸酿酒酵母生长繁殖抗逆性能香气

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基于折线模糊数多属性指标信息的FCM聚类算法

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系统工程理论与实践 2016年第12期36卷 3220-3228页

作者：段云王贵君天津师范大学数学科学学院天津300387

折线模糊数是借助实数的有序表示来确定一类模糊信息,它不仅可以按任意精度逼近一般模糊数,而且也克服了基于Zadeh扩展原理的模糊数四则运算的复杂性.该文首先引入折线模糊数定义及其有序表示,并给出它的扩展运算和度量公式.其次,采用... 详细信息

折线模糊数是借助实数的有序表示来确定一类模糊信息,它不仅可以按任意精度逼近一般模糊数,而且也克服了基于Zadeh扩展原理的模糊数四则运算的复杂性.该文首先引入折线模糊数定义及其有序表示,并给出它的扩展运算和度量公式.其次,采用折线模糊数的有序表示描述了待聚类对象的多属性指标信息,进而依据目标函数给出最优模糊划分(矩阵)和聚类中心的计算公式,并基于折线模糊数刻画多属性指标信息的模式提出(fuzzy c-means)FCM聚类算法.最后,通过算例说明该算法比梯形模糊数刻画指标信息更具优越性.

关键词：折线模糊数有序表示多属性指标信息模糊划分(矩阵) 聚类中心 FCM聚类算法

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真并发等价性下的流程模型转换方法

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西安交通大学学报 2012年第10期46卷 42-47页

作者：张曼段振华西安电子科技大学计算理论与技术研究所西安710071

针对工作流建模过程中流程模型的演化问题,在真并发等价性概念下,提出将图形化控制流模型转换为顺序与并发结构可分隔处理的可分离形式的方法.采用自由选择工作流网建模控制流模型,以完全并发互模拟为真并发等价概念,定义两个安全网间... 详细信息

针对工作流建模过程中流程模型的演化问题,在真并发等价性概念下,提出将图形化控制流模型转换为顺序与并发结构可分隔处理的可分离形式的方法.采用自由选择工作流网建模控制流模型,以完全并发互模拟为真并发等价概念,定义两个安全网间是完全并发互模拟关系的充分条件;基于Petri网的网展开,提出获得工作流网的可分离形式的局部网展开算法;通过证明局部展开网与原工作流网满足完全并发互模拟的充分条件,保证两个网模型的等价性.所提转换方法与已有方法相比,能够保留并发层次,且所需步骤更少,有利于流程模型的演化.

关键词：工作流 Petri网自由选择工作流网可分离工作流网真并发等价

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Differences in pseudogene evolution contributed to the contrasting flavors of turnip and Chiifu, two Brassica rapa subspecies

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Plant Communications 2023年第1期4卷 120-135页

作者： Xin Yin Danni Yang Youjie Zhao Xingyu Yang Zhili Zhou Xudong Sun Xiangxiang Kong Xiong Li Guangyan Wang Yuanwen duan Yunqiang Yang Yongping Yang Plant Germplasm and Genomics Center Kunming Institute of BotanyChinese Academy of SciencesKunming 650201China Key Laboratory for Plant Diversity and Biogeography of East Asia Kunming Institute of BotanyChinese Academy of SciencesKunming 650204China Institute of Tibetan Plateau Research at Kunming Kunming Institute of BotanyChinese Academy of SciencesKunming 650201China College of Big Data and Intelligent Engineering Southwest Forestry UniversityKunmingYunnanChina University of Chinese Academy of Sciences Beijing 100049China

Pseudogenes are important resources for investigation of genome evolution and genomic diversity because they are nonfunctional but have regulatory effects that influence plant adaptation and ***,few systematic comparative analyses of pseudogenes in closely related species have been ***,we present a turnip(Brassica rapa ***)genome sequence and characterize pseudogenes among diploid Brassica species/*** results revealed that the number of pseudogenes was greatest in Brassica oleracea(CC genome),followed by ***(AA genome)and then Brassica nigra(BB genome),implying that pseudogene differences emerged after species *** Brassica AA genomes,pseudogenes were distributed asymmetrically on chromosomes because of numerous chromosomal insertions/rearrangements,which contributed to the diversity among *** differences among subspecies were reflected in the flavor-related glucosinolate(GSL)***,turnip had the highest content of pungent substances,probably because of expansion of the methylthioalkylmalate synthase-encoding gene family in turnips;these genes were converted into pseudogenes in *** ***(Chiifu).RNA interference-based silencing of the gene encoding 2-oxoglutarate-dependent dioxygenase 2,which is also associated with flavor and anticancer substances in the GSL pathway,resulted in increased abundance of anticancer compounds and decreased pungency of turnip and *** findings revealed that pseudogene differences between turnip and Chiifu influenced the evolution of flavor-associated GSL metabolism-related genes,ultimately resulting in the different flavors of turnip and Chiifu.

关键词： turnip genome comparative genomics pseudogene evolution GSL biosynthesis flavor

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Natural Variation in the Promoter of GSE5 Contributes to Grain Size Diversity in Rice

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Molecular Plant 2017年第5期10卷 685-694页

作者： Penggen duan Jinsong Xu Dali Zeng Baolan Zhang Mufan Geng Guozheng Zhang Ke Huang Luojiang Huang Ran Xu Song Ge Qian Qian Yunhai Li State Key Laboratory of Plant Cell and Chromosome Engineering CAS Centre for Excellence in Molecular Plant Biology Institute of Genetics and Developmental Biology Chinese Academy of Sciences Beijing 100101 P. R. China State Key Laboratory of Rice Biology China National Rice Research Institute Hangzhou 310006 China State Key Laboratory of Systematic and Evolutionary Botany Institute of Botany Chinese Academy of Sciences Beijing 100093 P. R. China University of Chinese Academy of Sciences Beijing 100039 P. R. China These authors contributed equally to this article

The utilization of natural genetic variation greatly contributes to improvement of important agronomic traits in crops. Understanding the genetic basis for natural variation of grain size can help breeders develop high- yield rice varieties. In this study, we identify a previously unrecognized gene, named GSE5, in the qSW5/ GW5 locus controlling rice grain size by combining the genome-wide association study with functional analyses. GSE5 encodes a plasma membrane-associated protein with ｜Q domains, which interacts with the rice calmodulin protein, OsCaMl-1. We found that loss of GSE5 function caused wide and heavy grains, while overexpression of GSE5 resulted in narrow grains. We showed that GSE5 regulates grain size predominantly by influencing cell proliferation in spikelet hulls. Three major haplotypes of GSE5 （GSE5, GSE5DELl＋IN1, and GSESDEL~ in cultivated rice were identified based on the deletion/insertion type in its pro- moter region. We demonstrated that a 950-bp deletion （DELl） in indica varieties carrying the GSE5DELl＋IN1 haplotype and a 1212-bp deletion （DEL2） in japonica varieties carrying the GSE5DEL2 haplotype associated with decreased expression of GSE5, resulting in wide grains. Further analyses indicate that wild rice acces- sions contain all three haplotypes of GSE5, suggesting that the GSE5 haplotypes present in cultivated rice are likely to have originated from different wild rice accessions during rice domestication. Taken together, our results indicate that the previously unrecognized GSE5 gene in the qSW5/GW5 locus, which is widely utilized by rice breeders, controls grain size, and reveal that natural variation in the promoter region of GSE5 contributes to grain size diversity in rice.

关键词： rice natural variation GSE5 grain size cell proliferation

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Superresolution live-cell imaging reveals that the localization of TMEM106B to filopodia in oligodendrocytes is compromised by the hypomyelination-related D252N mutation

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Science China(Life Sciences) 2023年第8期66卷 1858-1868页

作者： Shijia Xing Xiaolu Zheng Huifang Yan Yanquan Mo Ruoyu duan Zhixing Chen Kunhao Wang Kai Gao Tongsheng Chen Shiqun Zhao Jingmin Wang Liangyi Chen National Biomedical Imaging Center State Key Laboratory of Membrane BiologyBeijing Key Laboratory of Cardiometabolic Molecular MedicineInstitute of Molecular MedicineCollege of Future TechnologyPeking UniversityBeijing 100871China Department of Pediatrics Peking University First HospitalBeijing 100034China PKU-IDG/McGovern Institute for Brain Research Beijing 100871China National Biomedical Imaging Center Institute of Molecular MedicineCollege of Future TechnologyPeking UniversityBeijing 100871China Key Laboratory of Laser Life Science Ministry of EducationCollege of BiophotonicsSouth China Normal UniversityGuangzhou 510631China National Center for Children’s Health Department of NeurologyBeijing Children’s HospitalCapital Medical UniversityBeijing 100045China

Hypomyelination leukodystrophies constitute a group of heritable white matter disorders exhibiting defective myelin *** identified as a lysosomal protein,the TMEM106B D252N mutant has recently been associated with ***,how lysosomal TMEM106B facilitates myelination and how the D252N mutation disrupts that process are poorly *** used superresolution Hessian structured illumination microscopy(Hessian-SIM)and spinning discconfocal structured illumination microscopy(SD-SIM)to find that the wild-type TMEM106B protein is targeted to the plasma membrane,filopodia,and lysosomes in human *** D252N mutation reduces the size of lysosomes in oligodendrocytes and compromises lysosome changes upon starvation *** importantly,we detected reductions in the length and number of filopodia in cells expressing the D252N ***1 is the most abundant myelin protein that almost entirely colocalizes with TMEM106B,and coexpressing PLP1 with the D252N mutant readily rescues the lysosome and filopodia phenotypes of ***,interactions between TMEM106B and PLP1 on the plasma membrane are essential for filopodia formation and myelination in oligodendrocytes,which may be sustained by the delivery of these proteins from lysosomes via exocytosis.

关键词： superresolution imaging oligodendrocyte TMEM106B lysosome filopodia

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基于干扰观测器的一类组合航天器高阶全驱抗干扰控制

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航空学报 2024年第1期45卷 66-78页

作者：崔凯鑫段广仁哈尔滨工业大学控制理论与制导技术研究中心哈尔滨150001 南方科技大学控制科学与技术研究中心深圳518055

研究了一类组合航天器的高阶全驱(HOFA)抗干扰控制,其干扰包括具有未知参数的输入端干扰和常值外部干扰。首先,引入一种一般化的离散时间高阶全驱后向差分模型,并对其中的2种干扰分别进行了干扰估计。其次,基于HOFA系统框架,设计了基于... 详细信息

研究了一类组合航天器的高阶全驱(HOFA)抗干扰控制,其干扰包括具有未知参数的输入端干扰和常值外部干扰。首先,引入一种一般化的离散时间高阶全驱后向差分模型,并对其中的2种干扰分别进行了干扰估计。其次,基于HOFA系统框架,设计了基于干扰观测器的复合控制器,不仅可以有效抑制干扰,而且能够得到一个可任意配置特征结构的闭环系统。然后,利用参数化方法,分别建立了观测器增益矩阵和反馈控制矩阵的完全参数化形式。最后,所提方法被应用于一类实际组合航天器模拟器,仿真和试验结果验证了所提方法的有效性。

关键词：组合航天器离散时间高阶全驱后向差分模型干扰观测器抗干扰控制参数化设计

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