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Elderly adults with COvID-19 admitted to intensive care unit:A narrative review

World Journal of Critical Care Medicine 2021年第5期10卷 278-289页

作者： Aikaterini Gkoufa Eleni Maneta Georgios n ntoumas vasiliki E Georgakopoulou Athina Mantelou Stelios Kokkoris Christina Routsi First Department of Internal Medicine Laiko General HospitalNational and Kapodistrian University of AthensAthens 11527Greece First Department of Intensive Care School of MedicineNational and Kapodistrian University of AthensAthens 10676Greece

BACKGROUnD In the context of the Coronavirus disease 2019(COvID-19)pandemic,it has been reported that elderly patients are particularly at risk of developing severe illness and exhibiting increased *** many studies on hospitalized elderly patients with COvID-19 have been published,limited information is available on the characteristics and clinical outcomes of those elderly patients admitted to intensive care unit(ICU).AIM To review the available evidence of the clinical data of elderly patients admitted to the ICU due to *** We searched for published articles available in English literature to identify those studies conducted in critically ill patients admitted to the ICU due to COvID-19,either exclusively designed for the elderly or for the whole ICU population with COvID-19,provided that analyses according to the patients’age had been *** Only one study exclusively focusing on critically ill elderly patients admitted to the ICU due to COvID-19 was *** additional studies involv.n. 17011 ICU patients and providing information for elderly patients as a subset of the whole study population have also been included in the present review *** the whole patient population,included in these studies,8310 patients were older than 65 years of age and 2630 patients were older than 70 *** manifestations were similar for all patients;however,compared to younger ones,they suffered from more comorbidities and showed a varied,albeit high *** In summary,at present,although elderly patients constitute a considerable proportion of critically ill patients admitted to the ICU due to severe COvID-19,studies providing specific information are *** evidence so far suggests that adv.n.ed age and comorbidities are associated with worse clinical *** studies exclusively designed for this vulnerable group are needed.

关键词： SARS-Cov-2 COvID-19 Elderly Critically ill Intensive care unit mortality Respiratory failure

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Rainfall and Temperature variations in a Dry Tropical Environment of nigeria

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Journal of Atmospheric Science Research 2023年第2期6卷 50-57页

作者： David O.Edokpa Precious n.Ede Bridget E.Diagi Susan I.Ajiere Department of Geography and Environmental Management Faculty of Social SciencesRivers State UniversityPort Harcourt500262Nigeria Department of Environmental Management Federal University of TechnologyOwerri460114Nigeria Department of Geography and Environmental Management University of Port HarcourtPort Harcourt500262Nigeria

This study examines long-term rainfall and temperature variations over a dry tropical environment in *** assessment of the variations of these weather variables showcases the extent of climate change limits and corresponding effects on the biotic *** and temperature data were obtained from nigerian Meteorological Agency for a period of 31 years(1991-2020)for Kano and Katsina *** statistics were used to determine the degree of variability of the weather variables across spatial *** showed that there is a sharp contrast in mean annual rainfall amounts of 1154.1 mm and 569.6 mm for Kano and Katsina located in the dry continental and semi-arid climate zones of nigeria *** is revealed that the month of August had the highest mean monthly rainfall for both areas i.e.359 mm and 194 mm with little or no trace during the dry *** sharp difference in rainfall amount across spatial domains of the near similar climate zones shows that the Inter-tropical Discontinuity(ITD)does not completely overwhelm the northern band of nigeria in *** least variable monthly rainfall was in August and July with coefficient variations(Cv)of 40%and 47%for Kano and *** months of February and March had the highest Cv of 557%and 273%for the respective *** the examined areas the wet and dry seasons are from June-September and October-May *** index of rainfall variability and drought intensity for the areas ranged from 0.85-0.95 and 45%indicating moderate variability and drought *** annual temperature values are 33.4℃and 33.8℃for Kano and *** study recommends a proper climate observ.n. scheme,most especially for agrarian practices so as to ensure profitable outputs for human sustainability.

关键词： Rainfall Air temperature Climate change Kano State Katsina State

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Fatigue Performance of Heat Treated TC21 Ti-Alloy

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Open Journal of Metal 2019年第2期9卷 11-18页

作者： Ramadan n. Elshaer Khaled M. Ibrahim Azza F. Barakat Reham R. Abbas Tabbin Institute for Metallurgical Studies Cairo Egypt Central Metallurgical R & D Institute Cairo Egypt Faculty of Engineering Helwan University Cairo Egypt Faculty of Engineering Suez University Suez Egypt

TC21 is considered a new titanium alloy that is used in aircraft applications as a replacement for the famous Ti-6Al-4v alloy due to its high strength. The effect of single and duplex stage heat treatments on fatigue behavior of TC21 Ti-alloy (Ti-6Al-2Sn-2Zr-3Mo-1Cr-2nb-0.09Si, wt.%) was investigated. Two heat treatment cycles were applied on as-received TC21 Ti-alloy. The first cycle was called single stage heat treatment (SSHT). The other cycle was named duplex stage heat treatment (DSHT). Typical microstructures of SSHT & DSHT composed of primary equiaxed α phase, residual β phase and secondary α phase (αs). Secondary α phase was precipitated in the residual β phase due to low cooling rate using air cooling and aging treatment. Morphology of α phase does not change after solution treatments, while their volume fraction and grain size were changed. SSHT showed the highest fatigue strength of 868 MPa due to high tensile strength, hardness and existing of high percentages of residual β phase in the microstructure. However, DSHT reported lower fatigue strength of 743 MPa due to increasing grain size of α phase. The fracture surface of fatigue samples showed cleavage ductile fracture mode for both heat treatment cycles.

关键词： TC21 Ti-Alloy Solution Treatment Microstructure Hardness Tensile Fatigue

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Preconcentration of Cadmium in Environmental Samples by Cloud Point Extraction and Determination by FAAS

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American Journal of Analytical Chemistry 2010年第3期1卷 127-134页

作者： C. Bosch Ojeda F. Sánchez Rojas J. M. Cano Pavón 不详

Cloud point extraction (CPE) has been used for the preconcentration of cadmium, after the formation of a complex with 1, 5-bis(di-2-pyridylmethylene) thiocarbonohydrazide (DPTH), and further determination by flame atomic absorption spectrometry (FAAS) using Triton X-114 as surfactant. The main factors affecting the CPE, such as concentration of Triton X-114 and DPTH, pH, equilibration temperature and incubation time, were optimized for the best extract efficiency. Under the optimum conditions i.e., pH 5.4, [DPTH] = 6x10-3%, [Triton X-114] = 0.25% (v/v), an enhancement factor of 10.5 fold was reached. The lower limit of detection (LOD) obtained under the optimal conditions was 0.95 μg L?1. The precision for 8 replicate deter- minations at 20 and 100 μgL?1 Cd were 2.4 % and 2 % relative standard deviation (R.S.D.). The calibration graph using the preconcentration method was linear with a correlation coefficient of 0,998 at levels close to the detection limit up to at least 200 μgL?1. The method was successfully applied to the determination of cadmium in water, environmental and food samples and in a BCR-176 standard reference material.

关键词： Cadmium Flame Atomic Absorption Spectrometry Cloud Point Extraction Triton X-114 Water Samples Food Samples

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慢性肾脏病:新版nICE指南摘要

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英国医学杂志中文版 2022年第7期25卷 413-416页

作者： Yolanda v Martinez Iv.n.Benett Andrew J P Lewington Anthony S Wierzbicki 无周津羽(译) 赵明辉(校) national Institute for Health and Care Excellence Manchester M14BDUK nHS ManchesterUK Renal Department St James's University HospitalLeedsUK Department of Metabolic Medicine/Chemical Pathology Guy's&St Thomas'HospitalsLondonUK on behalf of the Guideline Committee 北京大学第一医院肾内科

慢性肾脏病(CKD)很常见,在英国,约13%的成人(>16岁)患病1。从早期无症状到晚期肾衰竭,CKD患者临床表现多样[CKD分期和尿白蛋白/肌酐比值(ACR)分类见表1]。成人CKD患者中G3-G5期者占5%,在75岁及以上人群中这一比例升至34%。随着肾功能不... 详细信息

慢性肾脏病(CKD)很常见,在英国,约13%的成人(>16岁)患病1。从早期无症状到晚期肾衰竭,CKD患者临床表现多样[CKD分期和尿白蛋白/肌酐比值(ACR)分类见表1]。成人CKD患者中G3-G5期者占5%,在75岁及以上人群中这一比例升至34%。随着肾功能不全病情进展,死亡风险增加,心血管疾病风险也增加,部分共病(如糖尿病和高血压)更加严重。虽然大多数成人CKD的管理重点在一级保健,但随着疾病进展,他们需要更多二级保健管理。

关键词：慢性肾脏病死亡风险肾功能不全疾病进展晚期肾衰竭病情进展无症状二级保健

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new nCI-n87-derived human gastric epithelial line after human telomerase catalytic subunit over-expression

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World Journal of Gastroenterology 2015年第21期21卷 6526-6542页

作者： Kathy Saraiva-Pava nazanin navabi Emma C Skoog Sara K Lindén Mónica Oleastro Mónica Roxo-Rosa Faculdade de Engenharia Universidade Católica PortuguesaCampus de Sintra2635-631 Rio de MouroPortugal Department of Medical Biochemistry and Cell Biology Institute of BiomedicineUniversity of Gothenburg Departamento de Doen?as Infeciosas Instituto Nacional Saúde Dr.Ricardo Jorge1649-016 LisboaPortugal Chronic Diseases Research Center CEDOCNova Medical SchoolCampo Mártires da Pátria1169-056 LisboaPortugal

AIM:To establish a cellular model correctly mimicking the gastric epithelium to overcome the limitation in the study of Helicobacter pylori(***) ***:Aiming to overcome this limitation,clones of the heterogenic cancer-derived nCI-n87 cell line were isolated,by stably-transducing it with the human telomerase reverse-transcriptase(h TERT) catalytic subunit *** clones were first characterized regarding their cell growth pattern and *** that we measured the clones' adherence properties,expression of cell-cell junctions' markers(ZO-1 and E-cadherin) and ability to generate a sustained transepithelial electrical *** gastric properties of the clones,concerning expression of mucins,zymogens and glycan contents,were then evaluated by haematoxylin and eosin staining,Periodic acid Schiff(PAS) and PAS/Alcian Blue-staining,immunocytochemistry and Western *** addition,we assessed the usefulness of the h TERT-expressing gastric cell line for *** research,by performing co-culture assays and measuring the IL-8 secretion,by ELISA,upon infection with two *** strains differing in ***:Compared with the parental cell line,themost promising nCI-hT ERT-derived clones(CL5 and CL6) were composed of cells with homogenous phenotype,presented higher relative telomerase activities,better adhesion properties,ability to be maintained in culture for longer periods after confluency,and were more efficient in PAS-reactive mucins *** clones were shown to produce high amounts of MUC1,MUC2 and ***-hT ERT-CL5 mucins were shown to be decorated with blood group H type 2(BG-H),Lewis-x(Lex),Ley and Lea and,in a less extent,with BG-A antigens,but the former two antigens were not detected in the nCI-h *** of the clones exhibited detectable levels of MUC6 nor sialylated Lex and Lea *** good gastric properties,both nCIhT ERT-clones were found to produce pepsinogen-5 and human gastric *** progen

关键词： Helicobacter pylori infection Pathogenesis Human gastric epithelium Cellular model nCI-n87cells

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用元素周期表Ⅲ—Ⅷ族的元素来合金化超导化合物v3Ga

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稀有金属材料与工程 1975年第5期 56-59页

作者： В·Н·СВЕЧНnКОВ ,黄金昌

具有β—W（A15）型晶体结构的金属化合物v3Ga拥有较高的超导转变温度（根据不同的研究数据为14.5—16.5°K）,很高的上临界磁场（210—250KG）,和很高的临界电流密度。在一些文献中介绍了v—Ga系相平衡图。事实表明,具有体心立方晶格... 详细信息

具有β—W（A15）型晶体结构的金属化合物v3Ga拥有较高的超导转变温度（根据不同的研究数据为14.5—16.5°K）,很高的上临界磁场（210—250KG）,和很高的临界电流密度。在一些文献中介绍了v—Ga系相平衡图。事实表明,具有体心立方晶格的镓在钒中的固溶体形成了宽阔的单相区（51%Ga以下,原子百分比）,而化合物v3Ga是呈固态于1350℃生成的。加入各种元素进行合金化,研究其对化合物v3Ga超导性能的影响,无论从科学方面还是对解决可能的工艺任务来说都是很有意思的。文献中曾经研究过许多元素添加剂对化合物v3Ga临界温度的影响。文献中指出,在全部的研究工作中合金化都降低了临界温度,並且临界温度的降低照例因添加元素在周期表中的位置不同而不同。然而在文献中发现,添加硅铝稍微提高了临界温度（其值为～0.4°K）。文献的作者们在研究合金化合导致临界温度的变化时:在某些情况下显然没有考虑到合金的结构和相组成。而它们在以各种元素的任何原子组份进行合金化时却可能是完全不同的。本文研究了v3Ga—Me型合金的结构和相组成的变化,这里Me代表周期表中Ⅲ一Ⅷ族的元素。如同文献一样,在维持比例v:Ga=3:1的情况下,加入其量为5%Me（原子百分比,下同）的合金添加剂。

关键词：合金化化合物固溶体周期表 v3Ga 体心立方晶格铸态合金 ⅢB族元素稀土元素

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Optical to Mid-Infrared Analysis for the Galaxy Group RSCG 44

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International Journal of Astronomy and Astrophysics 2014年第1期4卷 54-69页

作者： J. A. Pérez-Grana S. n. Kemp J. P. Phillips Instituto de Astronomía y Meteorología Guadalajara México Instituto Tecnológico Superior de Chapala Ajijic México

We present the detailed Optical to Mid Infrared (MIR) analysis on the compact group of galaxies RSCG44. The optical analysis comprehends both photometric andspectroscopic studies for six galaxies in this group. The overall Optical to MIR data provide maps, spectra, profiles and images to analyse galaxy properties (structure, line-strength features, etc.) of each member searching for signatures of star formation and nucleus activity. In the photometric analysis, we study $BvR$ surface brightness and colors calculated for regions such as galaxy centers, possible bridges, tails and optical knots. Optical direct image also presents residual images (after subtracting isophotal models) and unsharp masked images in order to uncover any hidden structure in the system. The inclusion of maps, profiles and images from the Spitzer Space Telescope (SST) was made in order to provide a complementary outlook for the optical colors and the environment in which the group evolves, hence, a better explanation of the photospheric component and possible photdissociation regimes in polycyclic aromatic hydrocarbon (PAH) emission at 5.8 and 8 μm have provide a disentangled view of dust properties in the interstellar medium (ISM) at MIR. Optical spectra for the group are also provided to establish a more fond comparison between optical to mid infrared properties. The color gradients were compared with the optical spectra of both galaxies, showing in general similar trends for star formation. Globally, color maps, color tables and optical spectra indicate predominant stellar populations from classes I, III and v corresponding to spectral types of K-M stars with ages of at least in theorder of 10 Gyr for models using metallicity ranges with solar and non solar abundances. These results lead us to the conclusion of a moderate star formation rate and a tranquil evolv.n. state of the system.

关键词： Galaxy Photometry Galaxy Spectroscopy Galaxy Interactions Galaxies Evolution

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Imaging guided percutaneous interv.n.ions in hepatic dome lesions:Tips and tricks

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World Journal of Hepatology 2017年第19期9卷 840-849页

作者： Av.n.sh Kambadakone v.n.t Baliyan Hamed Kordbacheh Raul n Uppot Ashraf Thabet Debra A Gervais Ronald S Arellano Harvard Medical School Abdominal Imaging and Interventional RadiologyMassachusetts General HospitalBostonMA 02114United States

Percutaneous hepatic interv.n.ions are generally safe giv.n.the fact that liver closely abuts the abdominal wall and hence it is easily accessible. However, the superior portion of liver, adjacent to the diaphragm, commonly referred as the "hepatic dome", presents unique challenges for interv.n.ionists. Percutaneous access to the hepatic dome may be restricted by anatomical factors and special considerations may be required to avoid injury to the surrounding organs. The purpose of this review article is to discuss certain specific maneuvers and techniques that can enhance the success and safety of interv.n.ions in the hepatic dome.

关键词： Hepatic dome Radiofrequency ablation Hepatocellular carcinoma Percutaneous interv.n.ion

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Mechanical Properties and Effect of the MgO Content on the Dielectric Breakdown in the MgO/Binder Mixtures

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材料科学与工程（中英文B版） 2016年第1期6卷 48-53页

作者： Atef F. Qasrawi Iyad A. Sadeddin Attieh A. Alghamdi Haneen n. M. Jaradat Department of Physics Arab-American University Jenin 240 Palestine Department of Physics An-Najah N. University P. box 7 Nablus 407 Palestine Center of nanotechnology King Abdulaziz University Jeddah 21589 Saudi Arabia

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