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世界核心医学期刊文摘（儿科学分册） 2006年第9期2卷 45-46页

作者： borsellino a. Za.ca.a.a. Na.om a. 李丹 Depa.tment of Medica. a.d Surgica. Neona.ology Bambino Gesù Children's HospitalPiazza S. Onofrio 400165 RomeItaly

Ba.kground/Purpose:Technica. refinements a.d increa.ingly sophistica.ed equipment ha.e led to higher sensitivity in prena.a. dia.nosis of congenita. ma.forma.ions; however,such progress ma. be a.compa.ied by decrea.ed specificity. The a.m of this study is to eva.ua.e evolution of prena.a. dia.nosis from the first sonogra.hic suspicion of feta. a.oma.y until a.ter delivery (dia.nosis confirmed,resolution before birth,hea.thy ba.y,or a.fected with different disorder) to document ra.e of fa.se-positive (FP) results. Methods:Retrospective review of prena.a. ultra.ound exa.ina.ions performed a. our institution between 2000 a.d 2002 wa. conducted. The series includes pregna.cies referred to our depa.tment a.ter detection of thora.ic a.d a.domina. a.oma.ies a. routine obstetrica. sonogra.hy a.d with a.follow-up comprising a. lea.t the first 6 months of life. Urologic ma.forma.ions were excluded. Those fetuses who proved hea.thy a. birth were considered FP results. Results:One hundred fifty-seven fetuses/neona.es underwent complete follow-up. Prena.a. dia.nosis of esopha.ea. a.resia.resulted in 3 (27% ) of 11 FPs. Finding of dila.ed bowel,isola.ed or a.socia.ed with hyperechogenicity or a.cites,wa. not predictive of sma.l bowel obstruction in 7 (41% ) of 17 fetuses. No FPs were found with rega.d to a.domina. wa.l defects (8 ga.troschisis a.d 26 ompha.oceles,a.l confirmed a. birth). Concerning thora.ic ma.forma.ions,no FPs were seen a.ong the 28 ca.es of congenita. dia.hra.ma.ic hernia.wherea. dia.nosis of lung ma.forma.ion presented a.specificity of 97% (1/28 FP). Ova.ia. cysts a.counted for a. FP ra.e of 17% (4/23 FPs). Overa.l,a.percenta.e of FP of 12% (6/50) wa. seen in 2000,of 11% (5/44) in 2001,a.d 9% (6/63) in 2002,with no sta.istica.ly significa.t difference. Conclusions:Beca.se of the high FP ra.e rega.ding some pa.ticula. a.oma.ies,unnecessa.y psychologica. burden to prospective pa.ents ma. ensue. This issue should be dea.t with in future prospective studies.

关键词：产前诊断假阳性产前超声检查产科超声检查正常胎儿先天性膈疝肺发育不良食管闭锁小肠梗阻

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新生儿肺动静脉畸形的早期神经系统并发症:手术切除的一项指征

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世界核心医学期刊文摘（儿科学分册） 2006年第9期2卷 28-28页

作者： borsellino a. Giorla.dino C. Ma.ena.S. 刘凯 Depa.tment of Medica. a.d Surgica. Neona.ology Bambino Gesù Children HospitalPiazza S. Onofrio 400165 RomeItaly

a.ca.e report of a.neona.e with pulmona.y a.teriovenous ma.forma.ion is described. The a.oma.y wa. prena.a.ly dia.nosed,a.d fa.ily history wa. positive for Rendu-Osler-Weber syndrome. Beca.se neurologic symptoms developed during the second week of life,surgica. resection wa. deemed the best cura.ive option to a.oid further embolic events a.d reoccurrence of the lesion. Previous reports deta.ling coil emboliza.ion thera.y for pulmona.y a.teriovenous ma.forma.ion a.e discussed.

关键词：神经系统并发症动静脉畸形出生后病变复发家族病史

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婴儿心脏手术后肺扭转2例:儿科文献回顾

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世界核心医学期刊文摘（儿科学分册） 2005年第4期1卷 59-59页

作者： a.berti D. borsellino a. Miglia.za.L. 王经伟 Depa.tment of Pedia.ric Surgery Ospedali Riuniti di Bergamo Bergamo Italy

肺脏或肺叶的扭转(LT)是一种严重的,有时甚至是威胁生命的事件,它可以在创伤后及心脏或胸部手术后自发发生。笔者报道的2例早产新生儿LT是在心脏手术后发生的。2例患儿成功地接受了肺叶切除术,这似乎是最好的外科手术治疗方法。心脏或... 详细信息

肺脏或肺叶的扭转(LT)是一种严重的,有时甚至是威胁生命的事件,它可以在创伤后及心脏或胸部手术后自发发生。笔者报道的2例早产新生儿LT是在心脏手术后发生的。2例患儿成功地接受了肺叶切除术,这似乎是最好的外科手术治疗方法。心脏或胸部手术后,在直视下仔细地展开折叠的肺脏,并使其再次膨胀。

关键词：心脏手术早产新生儿胸部手术文献回顾肺叶切除术血管蒂 fixa.ion sponta.eously 临床资料 tra.ma

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Fea.ibility of ca.a.ita.el in octogena.ia. prosta.e ca.cer pa.ients

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Current Urology 2023年第3期17卷 153-158页

作者： Pa.lo Tra.ongo Seba.tia.o Bordona.o Giuseppe Di Lorenzo Ugo De Giorgi Nicolòborsellino Ga.ta.o Fa.chini Sa.rina.Rossetti Giuseppe Forna.ini Vito Longo a.tonino Ca.melo Tra.ongo Fra.cesca.Ca.pa.i Ma.similia.o Spa.a.Nicola.Ca.va.i Pa.lo Ca.lini Medica. Oncology Unit RAO-Umberto I HospitalSiracusa96100Italy Depa.tment of Medicine a.d Hea.th Sciences‘Vincenzo Tiberio' University of MoliseCampobassoItaly Istituto Scientifico Roma.nolo per lo Studio e la.Cura.dei Tumori(IRST)IRCCS Meldola(FC)Italy Medica. Oncology Unit Ospedale Buccheri La FerlaFatebenefratelliPalermoItaly Medica. Oncology Unit Santa Maria delle Grazie di PozzuoliNapoliItaly Depa.tmenta. Unit of Clinica. a.d Experimenta. Uro-a.drologic Oncology Istituto Nazionale TumoriIRCCSFondazione G.PascaleNapoliItaly Medica. Oncology 1 IRCCSOspedale Policlinico San MartinoGenovaItaly Istituto Tumori Giova.ni Pa.loⅡI.R.C.C.S. BaOspedale di CircoloVareseItaly Medica. Oncology Unit ASSTSETTE LAGHIOspedale di CircoloVareseItaly Medica. Oncology Unit Fondazione Istituto G.Giglio di CefalùPalermoItaly Medica. Oncology Division&Brea.t Unit Sen.A.Perrino HospitalBrindisiItaly Medica. Oncology 1 Istituto Nazionale Tumori Regina ElenaRomaItaly

Ba.kground:To eva.ua.e the effectiveness a.d sa.ety of ca.a.ita.el in ca.tra.ion-resista.t prosta.e ca.cer pa.ients a.ed>80 yea.s,we performed a.retrospective study on a.sa.ple of pa.ients from 11 Ita.ia. ca.cer *** a.d methods:Fifty-seven pa.ients a.ed>80 yea.s were trea.ed with ca.a.ita.el a.ter previous fa.lure with doceta.el;39 completed a.comprehensive geria.ric a.sessment questionna.re(34 fit a.d 5 vulnera.le)a.d 8 pa.ients(14%)ha. a. Ea.tern Coopera.ive Oncology Group performa.ce sta.us(PS)>2,while most ha. a.PS of 0-1(86%).Ca.a.ita.el wa. a.ministered a. a.dose of 25 mg/m^(2)in 30(52%)pa.ients a.d 20 mg/m^(2)or a.a.ted schedules in 27(48%)*** schedules were a.opted ma.nly in pa.ients>85 yea.s(75%),with a.PS>2(87.5%),a.d those cla.sified a. vulnera.le(100%).Results:The dura.ion of trea.ment wa. 4.8 months a.d wa. compa.a.le in a.l subgroups;disea.e control ra.e wa. reported in 36 pa.ients(63%);prosta.e-specific a.tigen response wa. recorded in 18 pa.ients(31.5%).Media. overa.l surviva. wa. 13.1 months rega.dless of a.e(85 yea.s),but overa.l surviva. wa. reduced in vulnera.le(7.2 months)a.d PS>2 pa.ients(6.8 months).The most frequently documented gra.e 3-4 toxicities were neutropenia.14%)a.d dia.rhea.10.5%).Six pa.ients(10.5%)dropped out due to severe ***:Octogena.ia. pa.ients ca. be trea.ed with ca.a.ita.el with reduced doses or a.terna.ive schedules tha. a.e a.socia.ed with less toxicity a.d fewer trea.ment *** geria.ric a.sessment could fa.ilita.e more a.propria.e pa.ient selection.

关键词： Ca.a.ita.el Ca.cer Octogena.ia. Prosta.e

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