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Performance of pulsed plasma thruster at low discharge energy

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Plasma Science and Technology 2024年第4期26卷 122-132页

作者：李鸿俊林泽豪胡浩俊吴文东陈爱虹杜德扬 Department of Physics Faculty of ScienceUniversity of MalayaKuala Lumpur 50603Malaysia Faculty of Engineering The University of Nottingham Malaysia CampusSemenyih 43500Malaysia Faculty of Engineering Multimedia UniversityCyberjaya 63100Malaysia

As the size of satellites scales down, low-power and compact propulsion systems such as the pulsed plasma thruster(PPT) are needed for stabilizing these miniature satellites in orbit. Most PPT systems are operated at 2 J or more of discharge energy. In this work, the performance of a PPT with a side-fed, tongue-flared electrode configuration operated within a lower discharge energy range of 0.5-2.5 J has been investigated. Ablation and charring of the polytetrafluoroethylene propellant surface were analyzed through field-effect scanning electron microscopy imaging and energy-dispersive X-ray spectroscopy. When the discharge energy fell below 2 J, inconsistencies occurred in the specific impulse and the thrust efficiency due to the measurement of the low mass bit. At energy ≥2 J, the performance parameters are compared with other PPT systems of similar configuration and discussed in depth.

关键词： pulsed plasma thruster low discharge energy performance parameters

Multiplex real-time PCR revealed very high prevalence of soil-transmitted helminth infections among aborigines in Peninsular Malaysia

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Asian Pacific Journal of Tropical Medicine 2020年第12期13卷 550-556页

作者： Nurulhasanah Othman Noorizan Miswan Weng-kin Wong boon.huat lim Rahmah Noordin Institute for Research in Molecular Medicine Universiti Sains Malaysia11800 PenangMalaysia School of Health Sciences Universiti Sains Malaysia16150 KelantanMalaysia

Objective:To determine the true prevalence of soil-transmitted helminth infections in the Malaysian aborigines using real-time ***:A total of 122 aborigines from seven tribes were recruited from settlements and nearby hospitals which served the communities,located in four states in Peninsular *** stool samples were examined for the presence of soil-transmitted helminth using real-time PCR and *** latter included the direct wet mount and formalin-ether concentration technique(FECT).The infection load in FECT-positive samples was determined by the Kato-Katz *** real-time analyzer detected five helminth species using two sets of ***:The real-time PCR detected soil-transmitted helminth in 98.4% samples(n=122),which were 1.56 times higher than by *** lumbricoides and Trichuris trichiura were detected in more than 90% of the samples,while hookworm was detected in 46.7%(Necator americanus) and 13.9%(Ancylostoma sp.)of the *** with previous reports on the Malaysian aborigines showed that the real-time PCR markedly improved the detection of Ascaris lumbricoides,hookworm and Strongyloides *** real-time PCR detected poly-helminths in 92.6%of the samples compared to 28.7% by *** addition,27 samples(22.1%) showed amplification of Strongyloides stercoralis ***:The real-time PCR showed very high prevalence rates of soil-transmitted helminth infections in the aborigines and is the recommended method for epidemiological investigation of soiltransmitted helminth infections in this population.

关键词： prevalence infections markedly

Beyond just a tight fortress:contribution of stroma to epithelial-mesenchymal transition in pancreatic cancer

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Signal Transduction and Targeted Therapy 2020年第1期5卷 328-339页

作者： Ashenafi Bulle Kian-huat lim Division of Oncology Department of Internal MedicineBarnes-Jewish Hospital and The Alvin J.Siteman Comprehensive Cancer CenterWashington University School of MedicineSt.LouisMO 63110USA

Novel effective treatment is direly needed for patients with pancreatic ductal adenocarcinoma(PDAC).Therapeutics that target the driver mutations,especially the KRAS oncoprotein and its effector cascades,have been *** is increasing clear that the extensive fibro-inflammatory stroma(or desmoplasia)of PDAC plays an active role in the progression and therapeutic resistance of *** desmoplastic stroma is composed of dense extracellular matrix(ECM)deposited mainly by the cancer-associatedfibroblasts(CAFs)and infiltrated with various types of immune *** dense ECM functions as a physical barrier that limits tumor vasculatures and distribution of therapeutics to PDAC *** addition,mounting evidence have demonstrated that both CAFs and ECM promote PDAC cells aggressiveness through multiple mechanisms,particularly engagement of the epithelial-mesenchymal transition(EMT)*** of a mesenchymal-like phenotype renders PDAC cells more invasive and resistant to therapyinduced ***,we critically review seminal and recent articles on the signaling mechanisms by which each stromal element promotes EMT in *** discussed the experimental models that are currently employed and best suited to study EMT in PDAC,which are instrumental in increasing the chance of successful clinical translation.

关键词： stroma transition render

Economic Assessment of Standby Diesel Generator for Peak Reduction in Commercial and Industrial Buildings:A Case Study in Malaysia

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Journal of Electronic Science and Technology 2017年第4期15卷 400-406页

作者： Kein huat Chua Yun Seng lim Jee Xiong Chew Universiti Tunku Abdul Rahman Cheras 43000 Malaysia

This paper outlines the barriers and potential benefits of using standby diesel generators in mitigating the peak demands for commercial and industrial customers. The feasibility of utilizing the standby diesel generators to reduce the electricity bills for customers is carried out by using the hybrid optimization model for electric renewable(HOMER)software. The size of the standby diesel generator and its operational duration are determined based on the lowest cost of electricity obtained from the evaluations. The economic assessments demonstrate that there is potential to reduce the electricity bills for commercial and industrial customers under the existing fuel price and tariffs. The commercial customers under the tariff C2 have the highest potential to save their electricity bills with the use of standby diesel generators for peak reduction. This study demonstrates the potential of the standby diesel generators in peak reduction.

关键词： Commercial and industrial customers cost of electricity hybrid optimization model for electric renewable(HOMER) peak reduction standby diesel generator

ATP translocation and chloroplast biology

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National Science Review 2019年第6期6卷 1073-1076页

作者： Chia P.Voon boon L.lim School of Biological Sciences University of Hong Kong

By studying changes in ATP levels in the plastids and cytosol of live plants using a Mg ATP2-specific F?rster resonance energy transfer（FRET）-based sensor, the entry of cytosolic ATP to the mature chloroplasts of Ar... 详细信息

关键词： ATP translocation and chloroplast biology

Complete Solution of Sun Tracking for Heliostat

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Communications in Theoretical Physics 2006年第1期45卷 165-166页

作者： CHEN Ying-Tian lim boon-Han lim Chern-Sing Department of Astronomy and Applied Physics University of Science and Technology of China Hefei 230026 China

A general solution of sun tracking for an arbitrarily oriented heliostat towards an arbitrarily located target on the earth is published. With the most general form of solar tracking formulae, it is seen that the used azimuthelevation, spinning-elevation tracking formulae etc. are the special cases of it. The possibilities of utilizing the general solution and its significance in solar energy engineering are discussed.

关键词： solar tracking azimuth-elevation spinning-elevation optical aberration heliostat

Stroma-targeting strategies in pancreatic cancer:Past lessons,challenges and prospects

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World Journal of Gastroenterology 2021年第18期27卷 2105-2121页

作者： Faran Polani Patrick M Grierson Kian-huat lim Division of Oncology Department of Internal MedicineBarnes-Jewish Hospital and The Alvin J.Siteman Comprehensive Cancer CenterWashington University School of MedicineSaint LouisMO 63110United States

Pancreatic ductal adenocarcinoma(PDAC)is projected to emerge as the second leading cause of cancer-related death after *** treatment resistance is perhaps the most significant factor that underlies the poor prognosis of *** date,combination chemotherapy remains the mainstay of treatment for most PDAC *** to other cancer types,treatment response of PDAC tumors to similar chemotherapy regimens is clearly much lower and *** from typically harboring genetic alterations that to date remain undruggable and are drivers of treatment resistance,PDAC tumors are uniquely characterized by a densely fibrotic stroma that has well-established roles in promoting cancer progression and treatment ***,emerging evidence also suggests that indiscriminate targeting and near complete depletion of stroma may promote PDAC aggressiveness and lead to detrimental *** conflicting results undoubtedly warrant the need for a more in-depth understanding of the heterogeneity of tumor stroma in order to develop modulatory strategies in favor of tumor *** advent of novel techniques including single cell RNA sequencing and multiplex immunohistochemistry have further illuminated the complex heterogeneity of tumor cells,stromal fibroblasts,and immune *** new knowledge is instrumental for development of more refined therapeutic strategies that can ultimately defeat this ***,we provide a concise review on lessons learned from past stromatargeting strategies,new challenges revealed from recent preclinical and clinical studies,as well as new prospects in the treatment of PDAC.

关键词： Stroma Pancreatic cancer Treatment resistance Cancer-associated fibroblasts Clinical trials

Discovery of Trichuris landak *** Endang Purwaningsih

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Asian Pacific Journal of Tropical Biomedicine 2013年第4期3卷 314-314页

作者： lim boon.huat Biomedicine Programme School of Health SciencesUniversiti Sains Malaysia16150 Kubang KerianKelantanMalaysia

Dear Editor,I wish to congratulate Endang Purwaningsih for publishing in Asian Pacific Journal of Tropical Biomedicine(APJTB)the important discovery of Trichuris landak ***.,a new species of whipworm that parasitizes porcupine in *** author separated the new species from the other Trichuris *** comparing the morphologic features and morphometric measurements of the adult *** approach was reported

关键词： morphologic publishing Tropical separated inevitably funding etiology statement Mexican Conflict

Digitalized Mirror Array and Its Application in Large Telescope:Principle and Case Studies

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Communications in Theoretical Physics 2009年第10期52卷 750-760页

作者： CHEN Ying-Tian ZHANG Yang HU Sen Ho Tso-Hsiu boon Ham lim Chen Sin lim Kok Keong Chong boon Kok Tan University of Science and Technology of China Department of Astronomy and Applied Physics Hefei 230026 China University of Science and Technology of China Department of Mathematics Hefei 230026 China Institute of Theoretical Physics Chinese Academy of Sciences Beijing 100190 China University of Tunku Abdul Rahman Faculty of Engineering and Science Selangor Malaysia

In this article, we report the principle and conceptual design of a fundamentally different technology in fabricating high precision aberration free optical devices. The tip-tilt of facet in a mirror array is produced by digitally controlled line-tilts of rows and columns. It has not only provided a cost-effective designing methodology in optical physics but also led to a much finer precision of 1 mili arc sec or less. As examples of the application of the proposed digitalised optics, two case studies have been given： a 10 m Schmidt telescope （off-axis） and an 8 m Cassegrain telescope （on-axis）.

关键词： tip-tilting line-tilting Schmidt telescope aberration correction cassegrain telescope