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A practical approach for scaling up the alternative strategy for the elimination of lymphatic filariasis in Loa loa endemic countries-developing an action plan

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Global Health Research and Policy 2017年第1期2卷 254-260页

作者： Louise A.Kelly-Hope Michelle C.Stanton Honorat G.M.Zouré boniface e.kinvi Alexei Mikhailov Afework Tekle Jonathan D.King Department of Parasitology Liverpool School of Tropical MedicineLiverpoolUK African Programme for Onchocerciasis Control OuagadougouBurkina Faso Communicable Disease Unit World Health OrganizationRegional Office for AfricaBrazzavilleCongo Department of Control of Neglected Tropical Diseases World Health OrganizationGenevaSwitzerland

Background:Lymphatic filariasis(LF)is a vector-borne parasitic disease that is being targeted for elimination through mass drug administration(MDA).The co-distribution of Loa loa in Central Africa poses a significant barrier to the expansion of the MDA due to risk of severe adverse events(SAes)associated with the drug ivermectin that is routinely *** LF programmes are yet to significantly scale up in co-endemic areas and need a practical approach to make preliminary decisions based on the mapping status and potential treatment ***:We reviewed relevant data available to WHO and in the literature for *** endemic countries to develop a simple method to support the scale-up of MDA to eliminate ***:A basic model for national LF programmes to work from at the administrative or implementation unit(IU)level has been developed for LF–*** co-endemic *** model includes five practical steps,which comprise the development of a national filarial database and a simple classification system to help determine the mapping status and most appropriate treatment *** are colour-coded and linked to a general decision tree,which is also ***:This IU-level model is simple to follow and will help LF elimination programmes develop an action plan and scale up the implementation of alternative treatment strategies in *** co-endemic *** model could be further developed to incorporate the additional complexity of IUs where an intervention is required to eliminate onchocerciasis,particularly in hypo-endemic areas where ivermectin has not been used.

关键词： routine elimination action

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