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Neural Regeneration Research 2020年第9期15卷 1767-1768页

作者： Sung ho Jang Han Do lee Department of Physical Medicine and Rehabilitation College of MedicineYeungnam UniversityDaeguRepublic of Korea Department of Physical Therapy College of Natural ScienceUlsan College UniversityUlsanRepublic of Korea

Consciousnessiscontrolledbytheascendingreticularactivating system (ARAS)(Teasdale and Jennett, 1974;Jang and lee, 2015;Jang et al., 2016a). Scientific medical strategies for recovery in patients with impaired consciou... 详细信息

关键词： impaired system consciousness

The extract of the immature fruit of Poncirus trifoliata induces apoptosis in colorectal cancer cells via mitochondrial autophagy

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Food Science and Human Wellness 2020年第3期9卷 237-244页

作者： Sun-Young Kim ho-Keun Yi bong-Sik Yun Dae-Yeol lee Pyung Han Hwang Hae-Ryong Park Min Sun Kim Research Institute of Clinical Medicine of Jeonbuk National University Biomedical Research Institute of Jeonbuk National University HospitalJeonju54907South Korea Department of Oral Biochemistry Institute of Oral BioscienceSchool of DentistryJeonbuk National UniversityJeonju54907South Korea Division of Biotechnology and Advanced Institute of Environment and Bioscience Jeonbuk National UniversityIksan-si54596South Korea Department of Pediatrics Jeonbuk National University Medical SchoolJeonju54907South Korea Department of Food Science and Biotechnology Kyungnam UniversityChangwon-si51767South Korea

The immature fruits of Poncirus trifoliate are used as a medicine for the treatment of gastrointestinal disorders,inflammation,and allergies in East ***,their effect on colon cancer cells remains *** investigated the effect of the immature fruit of *** extract on colorectal *** extract of the immature fruit of *** inhibited the proliferation of CT-26 cells compared with untreated cells and it induced autophagy and apoptosis through the protein kinase B/mammalian target of rapamycin and 5'-AMP-activated protein kinase *** number of autophagic vacuoles and autophage markers increased in response to the *** later time-points,apoptosis increased dose/*** CT-26 cells pre-treated a pan-caspase inhibitor prior to *** immature fruit extract treatment,we did not find any change in pro-caspase 3 and pro-PARP ***,in cells pre-treated autphage inhibitor,SQSTM1/p62 and LC3AB,pro-caspase 3 and pro-PARP levels did not *** results indicate the molecular mechanisms that the extract of the immature fruit of *** induces apoptosis in colorectal carcinoma cells by inducing mitochondrial *** this study,we provided a draft for further investigate the use of MEPT for colorectal cancer inhibition.

关键词： Anticancer Autophagy Apoptosis Mitochondria Poncirus trifoliata

The effects of Y pre-alloying on the in-situ dispersoids of ODS Co Cr Fe Mn Ni high-entropy alloy

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Journal of Materials Science & Technology 2021年第26期85卷 62-75页

作者： SeungHyeok Chung Bin lee Soo Yeol lee Changwoo Do ho Jin Ryu Department of Nuclear and Quantum Engineering Korea Advanced Institute of Science and TechnologyDaejeon 34141Republic of Korea Manufacturing Technology Office Korea Institute for Rare MetalKorea Institue of Industrial TechnologyGet-Pearl TowerGaetbeol-ro 12Yeonsu-guIncheon 21999Republic of Korea Department of Materials Science and Engineering Chungnam National UniversityDaejeon 34134Republic of Korea Neutron Scattering Division Oak Ridge National LaboratoryOak RidgeTN 37831USA

Oxide dispersion strengthened CoCrFeMnNi high-entropy alloys(ODS-HEAs)were prepared using two different powder preparation methods classified by yttrium addition strategy to investigate the effects of in-situ and ex-situ oxide dispersoid formation on the microstructure and mechanical *** micro structural analysis was carried out by X-ray diffraction(XRD),electron backscattered diffraction(EBSD),high-resolution transmission electron microscopy(HRTEM),atom probe tomography(APT),and small-angle neutron scattering(SANS).Cryo-milled powder analysis,grain structure evolution after spark plasma sintering,dispersoid characteristics,and matrix/dispersoid interface structure analysis of the insitu and ex-situ dispersoids within the high-entropy alloy(HEA)matrix were *** in-situ dispersoid formation was dominantly observed in the Y-alloyed ODS-HEA through the construction of a coherent interface relationship with complex chemical composition,leading to an increase in the Zener pinning forces on the grain boundary ***-HEA with in-situ oxide dispersoids enhanced the formation of ultrafine-grained structures with an average diameter of 330 nm at a sintering temperature of 1173 *** study shows that the Y pre-alloying method is efficient in achieving fine coherent dispersoids with an ultra fine-grained structure,resulting in an enhancement of the tensile strength of the CoCrFeMnNi HEA.

关键词： Oxide dispersion strengthened(ODS)alloy High-entropy alloy In-situ oxide dispersoid formation Microstructure Mechanical property

Effect of In Composition on Two-Dimensional Electron Gas in Wurtzite AlGaN/InGaN Heterostructures

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Chinese Physics Letters 2010年第11期27卷 188-190页

作者： KIM bong-Hwan PARK Seoung-Hwan lee Jung-Hee MOON Yong-Tae Department of Electronics Engineering Catholic University of Daegu Hayang Kyeongsan Kyeongbuk 712-702 R. Korea School of Electrical Engineering and Computer Science Kyungpook National University Daegu 702-701 R. Korea LG Corporate Institute of Technology 16 Woomyeon-dong Seocho-gu Seoul 137-14-0 R. Korea

The effect of In composition on two-dimensional electron gas in wurtzite AlGaN/InGaN heterostructures is theoretically investigated. The sheet carrier density is shown to increase nearly linearly with In mole fraction x, due to the increase in the polarization charge at the AlGaN/InGaN interface. The electron sheet density is enhanced with the doping in the AlGaN layer. The sheet carrier density is as high as 3.7×1013 cm^-2 at the donor density of 10×1018 cm^-3 for the HEMT structure with x=0.3. The contribution of additional donor density on the electron sheet density is nearly independent of the In mole fraction.

关键词： Condensed matter: electrical magnetic and optical Electronics and devices Semiconductors Surfaces interfaces and thin films Condensed matter: structural mechanical & thermal Nanoscale science and low-D systems

Estimation of Turbulent Sensible Heat and Momentum Fluxes over a Heterogeneous Urban Area Using a Large Aperture Scintillometer

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Advances in Atmospheric Sciences 2015年第8期32卷 1092-1105页

作者： Sang-Hyun lee Jun-ho lee Bo-Young KIM Department of Atmospheric Science Kongju National University Department of Optical Engineering Kongju National University

The accurate determination of surface-layer turbulent fluxes over urban areas is critical to understanding urban boundary layer （UBL） evolution. In this study, a remote-sensing technique using a large aperture scintillometer （LAS） was investigated to estimate surface-layer turbulent fluxes over a highly heterogeneous urban area. The LAS system, with an optical path length of 2.1 km, was deployed in an urban area characterized by a complicated land-use mix （residential houses, water body, bare ground, etc.）. The turbulent sensible heat （QH） and momentum fluxes （z） were estimated from the scintillation measurements obtained from the LAS system during the cold season. Three-dimensional LAS footprint modeling was introduced to identify the source areas （＂footprint＂） of the estimated turbulent fluxes. The analysis results showed that the LAS-derived turbulent fluxes for the highly heterogeneous urban area revealed reasonable temporal variation during daytime on clear days, in comparison to the land-surface process-resolving numerical modeling. A series of sensitivity tests indicated that the overall uncertainty in the LAS-derived daytime QH was within 20%-30% in terms of the influence of input parameters and the non- dimensional similarity function for the temperature structure function parameter, while the estimation errors in z were less sensitive to the factors of influence, except aerodynamic roughness length. The 3D LAS footprint modeling characterized the source areas of the LAS-derived turbulent fluxes in the heterogeneous urban area, revealing that the representative spatial scales of the LAS system deployed with the 2.1 km optical path distance ranged from 0.2 to 2 km2 （a ＂micro-a scale＂）, depending on local meteorological conditions.

关键词： heterogeneous surface large aperture scintillometer mesoscale modeling surface energy balance turbulentexchange

The association between C-reactive protein to albumin ratio and 6-month neurological outcome in patients with in-hospital cardiac arrest

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World Journal of Emergency Medicine 2024年第3期15卷 223-228页

作者： Ji ho lee Dong Hun lee Byung Kook lee Seok Jin Ryu Department of Emergency Medicine Chonnam National University HospitalGwangju 61469Republic of Korea Department of Emergency Medicine Chonnam National University Medical SchoolGwangju 61469Republic of Korea

The global incidence rates of in-hospital cardiac arrest(IHCA)range from1.2 to 9.0 per1,000 hospitalized patients,as per the National Cardiac Arrest Database.[1] While IHCAs tend to exhibit superior 30-day survival rates relative to out-of-hospital cardiac arrests (OHCA) due to situational advantages,such as immediate access to medical personnel and treatments.

关键词： patients cardiac IHC

Food intolerance and skin prick test in treated and untreated irritable bowel syndrome

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World Journal of Gastroenterology 2006年第15期12卷 2382-2387页

作者： Dae-Won Jun Oh-Young lee ho-Joo Yoon Seok-Hwa lee Hang-Lak lee ho-Soon Choi Byung-Chul Yoon Min-ho lee Dong-hoo lee Sang-hoen Cho Department of Internal Medicine College of Medicine Hanyang UniversitySeoulKorea Department of Food and Nutrition College of Human Ecology Hanyang UniversitySeoulKorea Department of Internal Medicine College of Medicine Seoul National UniversitySeoulSouth Korea

AIM： To correlate the clinical features of treated and untreated patients with irritable bowel syndrome （IBS） to the results of skin prick test （SPT） for food and inhalant allergens. METhoDS： We recruited 105 subjects to form three different target groups： treated group （n=44） undergoing treatment for IBS, untreated group （n =31） meeting the Rome Ⅱ criteria without treatment for IBS, control group （n = 30） with no IBS symptoms. RESULTS： SPT results were different among the three groups in which SPT was positive in 17 （38.6%） treated patients, in 5 （16.1%） untreated patients and in 1 （3.3%） control （P〈0.01）. The number of positive SPTs was greater in the IBS group than in the control group （P〈 0.001）. The number of positive food SPTs was higher in the treated IBS group than in the untreated IBS group （P= 0.03）. CONCLUSION： Positive food SPT is higher in IBS patients than in controls.

关键词： Irritable bowel syndrome Skin prick test Food allergy

Surface-roughened current collectors for anode-free all-solid-state batteries

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Journal of Energy Chemistry 2022年第7期31卷 248-257,I0007页

作者： Donghee Gu Hyoungchul Kim Jong-ho lee Sangbaek Park Energy Materials Research Center Korea Institute of Science and Technology(KIST)Seoul 02792.Republic of Korea School of Civil Environmental and Architectural EngineeringKorea University.Seoul 02841.Republic of Korea Division of Nanoscience and Technology University of Science and Technology(UST)Seoul02792.Republicof Korea Department of Materials Science and Engineering Chungnam National UniversityDaejeon 34134.Republic of Korea

Anode-free all-solid-state batteries(AFASSBs), composed of a fully lithiated cathode and a bare current collector(CC) that eliminates excess lithium, can maximize the energy density(because of a compact cell configuration) and improve the safety of solid-state systems. Although significant progress has been made by modifying CCs in liquid-based anode-free batteries, the role of CCs and the mechanism of Li formation on CCs in AFASSBs are still unexplored. Here, we systematically investigate the effect of the surface roughness of the CCs on the Li plating/stripping behavior in AFASSBs. The results show that the moderately roughened CC substantially improves the Coulombic efficiency and cycle stability of AFASSBs owing to the increased contact points between the solid electrolyte and the roughened CC. In contrast, the excessively roughened CC deteriorates the performance owing to the contact ***, an ex situ interface analysis reveals that the roughened surface of the CC could suppress the interfacial degradation during the Li ion extraction from a sulfide solid electrolyte to a CC. This provides an indication to the origin that hinders the electrochemical performance of AFASSBs. These findings show the potential for the application of surface-engineered CCs in AFASSBs and provide guidelines for designing advanced CCs.

关键词： Anode-free Solid-state batteries Current collectors Surface roughness Li formation

Effects of TiC on the microstructure refinement and mechanical property enhancement of additive manufactured Inconel 625/TiC metal matrix composites fabricated with novel core-shell composite powder

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Journal of Materials Science & Technology 2023年第33期164卷 13-26页

作者： Taegyu lee Wonjong Jeong SeungHyeok Chung ho Jin Ryu Department of Materials Science and Engineering Korea Advanced Institute of Science and TechnologyYu Seong-GuDae Hak-Ro 29134141 DaejeonRepublic of Korea Department of Nuclear and Quantum Engineering Korea Advanced Institute of Science and TechnologyYu Seong-GuDae Hak-Ro 29134141 DaejeonRepublic of Korea

The flexible product shape of additive manufacturing(AM)is attractive,but the process suffers from a lack of material property diversity due to a limited number of printable alloys and post-processing *** overcome this problem,the AM of metal matrix composites(MMCs)is a highly suitable solution because the properties of MMC can be tailored using various ***,extensive research has been conducted on the AM of MMCs;however,the major huddle for this process has been the difficulties in preparing feedstock powder and operating the AM *** study introduces an easily synthesizable core-shell composite powder,which was fabricated by a recently developed process called the SMART *** core-shell powder has a novel morphology,consisting of a metal core and composite shell,distinguishing it from the powders used in conventional AM *** 625/TiCp composites were fabricated using the core-shell composite powder,with various fractions of TiCp up to 10 vol.%.Compared to additive-manufactured Inconel 625,the additive-manufactured MMCs showed enhanced strength with significantly fewer *** results of this study may accelerate the application of MMC fabricated by AM,which offers superior properties and reliability compared to casting and powder metallurgy due to the higher degree of dislocation density and reinforcement dispersion.

关键词： Powder treatment Composite powder Metal matrix composite Additive manufacturing Nickel-based superalloy Directed energy deposition

Process of establishing design requirements and selecting alternative configurations for conceptual design of a VLA

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Chinese Journal of Aeronautics 2017年第2期30卷 738-751页

作者： Bo-Young Bae Sangho Kim Jae-Woo lee Nhu Van Nguyen bong-Cheul Chung Department of Aerospaee Information Engineering Konkuk University Seoul 143-701 Republic of Korea Konkuk Aerospace Design Airworthiness Research Institute Konkuk University Seoul 143-701 Republic of Korea

In this study,a process for establishing design requirements and selecting alternative configurations for the conceptual phase of aircraft design has been *** proposed process uses system-engineering-based requirement-analysis techniques such as objective tree,analytic hierarchy process,and quality function deployment to establish logical and quantitative ***,in order to perform a logical selection of alternative aircraft configurations,it uses advanced decision-making methods such as morphological matrix and technique for order preference by similarity to the ideal *** addition,a preliminary sizing tool has been developed to check the feasibility of the established performance requirements and to evaluate the flight performance of the selected *** present process has been applied for a two-seater very light aircraft（VLA）,resulting in a set of tentative design requirements and two families of VLA configurations：a high-wing configuration and a low-wing *** resulting set of design requirements consists of three categories：customer requirements,certification requirements,and performance *** performance requirements include two mission requirements for the flight range and the endurance by reflecting the customer *** flight performances of the two configuration families were evaluated using the sizing tool developed and the low-wing configuration with conventional tails was selected as the best baseline configuration for the VLA.

关键词： Aircraft configuration Conceptional design Design requirements Requirement analysis Very light aircraft (VLA)