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A Non-Parametric Scheme for Identifying Data Characteristic Based on Curve Similarity Matching

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IEEE/CAA Journal of Automatica Sinica 2024年第6期11卷 1424-1437页

作者： Quanbo Ge Yang Cheng Hong Li Ziyi Ye Yi Zhu Gang yao School of Automation Nanjing University of Information Science&TechnologyJiangsu Provincial University Key Laboratory of Big Data Analysis and Intelligent SystemsNanjing University of Information Science&Technologyand the Jiangsu Collaborative Innovation Center of Atmospheric Environment and Equipment Technology(CICAEET)Nanjing University of Information Science&TechnologyNanjing 210044China School of Department of Logistics Engineering Shanghai Maritime UniversityShanghai 201306China China Classification Society Nantong Office Nantong 226006China Chinese Flight Test Establishment Xi’an 710089China School of Mathematics Tsinghua UniversityBeijing 100084China School of Automation Nanjing University of Information Science&TechnologyNanjing 210044China Department of Logistics Engineering Shanghai Maritime UniversityShanghai 201306China IEEE

For accurately identifying the distribution charac-teristic of Gaussian-like noises in unmanned aerial vehicle(UAV)state estimation,this paper proposes a non-parametric scheme based on curve similarity *** the framework of the pro-posed scheme,a Parzen window(kernel density estimation,KDE)method on sliding window technology is applied for roughly esti-mating the sample probability density,a precise data probability density function(PDF)model is constructed with the least square method on K-fold cross validation,and the testing result based on evaluation method is obtained based on some data characteristic analyses of curve shape,abruptness and *** com-parison simulations with classical methods and UAV flight exper-iment shows that the proposed scheme has higher recognition accuracy than classical methods for some kinds of Gaussian-like data,which provides better reference for the design of Kalman filter(KF)in complex water environment.

关键词： Curve similarity matching Gaussian-like noise non-parametric scheme parzen window.

In situ direct reprogramming of astrocytes to neurons via polypyrimidine tract-binding protein 1 knockdown in a mouse model of ischemic stroke

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Neural Regeneration Research 2024年第10期19卷 2240-2248页

作者： Meng Yuan yao Tang Tianwen Huang Lining Ke En Huang Key Laboratory of Brain Aging and Neurodegenerative Diseases of Fujian Province Fujian Medical UniversityFuzhouFujian ProvinceChina Department of Human Anatomy School of Basic Medical SciencesFujian Medical UniversityFuzhouFujian ProvinceChina Scientific Research Center School of Basic Medical SciencesFujian Medical UniversityFuzhouFujian ProvinceChina Department of Neurology Fujian Medical University Union HospitalFuzhouFujian ProvinceChina Fujian Key Laboratory of Vascular Aging Fujian Medical UniversityFuzhouFujian ProvinceChina

In situ direct reprogramming technology can directly convert endogenous glial cells into functional neurons in vivo for central nervous system repair. Polypyrimidine tract-binding protein 1(PTB) knockdown has been shown to reprogram astrocytes to functional neurons in situ. In this study, we used AAV-PHP.e B-GFAP-sh PTB to knockdown PTB in a mouse model of ischemic stroke induced by endothelin-1, and investigated the effects of GFAP-sh PTB-mediated direct reprogramming to neurons. Our results showed that in the mouse model of ischemic stroke, PTB knockdown effectively reprogrammed GFAP-positive cells to neurons in ischemic foci, restored neural tissue structure, reduced inflammatory response, and improved behavioral function. These findings validate the effectiveness of in situ transdifferentiation of astrocytes, and suggest that the approach may be a promising strategy for stroke treatment.

关键词： astrocyte in situ direct reprogramming ischemic stroke miR-30 based shRNA neuron polypyrimidine tract-binding protein 1 transdifferentiation

An Intelligent Privacy Protection Scheme for Efficient Edge Computation Offloading in IoV

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Chinese Journal of Electronics 2024年第4期33卷 910-919页

作者： Liang yao Xiaolong XU Wanchun DOU Muhammad Bilal School of Software Nanjing University of Information Science and Technology State Key Laboratory for Novel Software Technology Nanjing University Department of Computer and Electronics Systems Engineering Hankuk University of Foreign Studies

As a pivotal enabler of intelligent transportation system(ITS), Internet of vehicles(Io V) has aroused extensive attention from academia and industry. The exponential growth of computation-intensive, latency-sensitive,and privacy-aware vehicular applications in Io V result in the transformation from cloud computing to edge computing,which enables tasks to be offloaded to edge nodes(ENs) closer to vehicles for efficient execution. In ITS environment,however, due to dynamic and stochastic computation offloading requests, it is challenging to efficiently orchestrate offloading decisions for application requirements. How to accomplish complex computation offloading of vehicles while ensuring data privacy remains challenging. In this paper, we propose an intelligent computation offloading with privacy protection scheme, named COPP. In particular, an Advanced Encryption Standard-based encryption method is utilized to implement privacy protection. Furthermore, an online offloading scheme is proposed to find optimal offloading policies. Finally, experimental results demonstrate that COPP significantly outperforms benchmark schemes in the performance of both delay and energy consumption.

关键词： Industries Privacy Energy consumption Transportation Computational efficiency Encryption Protection

Preparation of baicalin colon-targeted granules and its intervention effect on ulcerative colitis in rats

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Particuology 2024年第2期85卷 13-21页

作者： Yongqing Huang Yuxin Zhou yao Shen Jin Wang Liangliang Zhou Zhenhua Chen Jiangxi Provincial Key Laboratory of Drug Design and Evaluation School of PharmacyJiangxi Science and Technology Normal UniversityNanchang330013China

Baicalin(BA)is a flavonoid extracted from the dried root of Scutellaria baicalensis Georgi with excellent antioxidant and anti-inflammatory biological *** this study,Eudragit S100 was used as the colonic target material to prepare BA colonic targeting granules(EBCGs)based on plasticizer dry powder coating technology to improve the targeting transportation performance of *** vitro studies showed that EBCGs with pH-sensitive properties were successfully prepared by plasticizer dry powder coating,and in vivo animal imaging studies showed that EBCGs could deliver BA to the colon and inhibit the release of BA in the upper gastrointestinal tract(GIT).In vivo studies showed that EBCGs had good therapeutic effects in colitis,which reduced expression levels of tumor necrosis factor alpha(TNF-α)and interleukin-1β(IL-1β)and increased superoxide dismutase(SOD)activities in the colonic tissues of rats with *** conclusion,Eudragit S100 could be used for the preparation of multi-unit oral colon-targeted formulations by plasticizer dry powder coating technology,and our prepared EBCGs had good colon-targeting properties,which could improve the therapeutic effect and provide a potential application for ulcerative colitis(UC).

关键词： Plasticizer dry powder coating Colon-targeted granulesIn vivo imaging Ulcerative colitis

Synthesis of betanin by expression of the core betalain biosynthetic pathway in carrot

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Horticultural Plant Journal 2024年第3期10卷 732-742页

作者： Bo Wang Yahui Wang Yuanjie Deng Quanhong yao Aisheng Xiong State Key Laboratory of Crop Genetics and Germplasm Enhancement College of HorticultureNanjing Agricultural UniversityNanjingJiangsu 210095China Shanghai Key Laboratory of Agricultural Genetics and Breeding Biotechnology Research Institute of Shanghai Academy of Agricultural ScienceShanghai 201106China

Betalain has received increased attention because of its high nutritional value and crucial physiological *** on the elucidation of its core biosynthetic pathway,betalain can be produced in additional plants by metabolic *** of betalain in carrot(Daucus carota L.)can improve its nutritional quality and economic value by extracting betalain from the fleshy root,non-edible part,and processing residue of *** this study,two different constructs,namely,pYB:mCD(AomelOS,BvCYP76AD1S,and BvDODA1S)and p YB:CDD(BvCYP76AD1S,BvDODA1S,and MjcDOPA5GTS),were introduced into carrot for betanin synthesis by Agrobacterium-mediated *** can be synthetized in both transgenic calli,and p YB:m CD-transgenic callus can be used to produce betacyanin by suspension ***,pYB:mCD-transgenic seedlings can synthetize betanin only by tyrosine *** p YB:CDD-transgenic lines can synthetize betanin in whole *** betanin content in fleshy root of pYB:CDD-transgenic carrot was(63.4±9)μg·g^(-1)fresh weight according to quantitative *** betanin-producing carrot plant materials can be used to synthesize betanin for industrial application or consumption as dietary sources.

关键词： Daucus carota L. Betanin Biosynthesis Metabolic engineering Biofortification

Dielectric metasurface evolution from bulk to monolayer by strong coupling of quasi-BICs for second harmonic boosting

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Photonics Research 2024年第4期12卷 784-792页

作者： YINONG XIE QIANTING CHEN JIN yao XUEYING LIU ZHAOGANG DONG JINFENG ZHU Institute of Electromagnetics and Acoustics and Key Laboratory of Electromagnetic Wave Science and Detection Technology Xiamen UniversityXiamen 361005China Shenzhen Research Institute of Xiamen University Shenzhen 518057China Department of Electrical Engineering City University of Hong KongHong Kong 999077China Institute of Materials Research and Engineering(IMRE) Agency for ScienceTechnology and Research(A*STAR)Singapore 138634Singapore Department of Materials Science and Engineering National University of SingaporeSingapore 117575Singapore

2D materials are promising candidates as nonlinear optical components for on-chip devices due to their ultrathin structure. In general, their nonlinear optical responses are inherently weak due to the short interaction thickness with light. Recently, there has been great interest in using quasi-bound states in the continuum (q-BICs) of dielectric metasurfaces, which are able to achieve remarkable optical near-field enhancement for elevating the second harmonic generation (SHG) emission from 2D materials. However, most studies focus on the design of combining bulk dielectric metasurfaces with unpatterned 2D materials, which suffer considerable radiation loss and limit near-field enhancement by high-quality q-BIC resonances. Here, we investigate the dielectric metasurface evolution from bulk silicon to monolayer molybdenum disulfide (MoS2), and discover the critical role of meta-atom thickness design on enhancing near-field effects of two q-BIC modes. We further introduce the strongcoupling of the two q-BIC modes by oblique incidence manipulation, and enhance the localized optical field on monolayer MoS2dramatically. In the ultraviolet and visible regions, the MoS2SHG enhancement factor of our design is 105times higher than that of conventional bulk metasurfaces, leading to an extremely high nonlinear conversion efficiency of 5.8%. Our research will provide an important theoretical guide for the design of high-performance nonlinear devices based on 2D materials.

关键词： monolayer harmonic quasi

Porous TiFe_(2) intermetallic compound fabricated via elemental powder reactive synthesis

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International Journal of Minerals,Metallurgy and Materials 2024年第4期31卷 764-772页

作者： Qian Zhao Zhenli He Yuehui He Yue Qiu Zhonghe Wang yao Jiang State Key Laboratory of Powder Metallurgy Powder Metallurgy Research InstituteCentral South UniversityChangsha 410083China

Porous intermetallics show potential in the field of filtration and separation as well as in the field of ***,porous Ti Fe2intermetallics were fabricated by the reactive synthesis of elemental *** phase transformation and pore formation of porous TiFe2intermetallics were investigated,and its corrosion behavior and hydrogen evolution reaction(HER)performance in alkali solution were *** TiFe2intermetallics with porosity in the range of 34.4%-56.4%were synthesized by the diffusion reaction of Ti and Fe elements,and the pore formation of porous TiFe2intermetallic compound is the result of a combination of the bridging effect and the Kirkendall *** porous TiFe2samples exhibit better corrosion resistance compared with porous 316L stainless steel,which is related to the formation of uniform nanosheets on the surface that hinder further corrosion,and porous TiFe2electrode shows the overpotential of 220.6 and 295.6 mV at 10 and 100 mA·cm-2,suggesting a good catalytic *** synthesized porous Fe-based intermetallic has a controllable pore structure as well as excellent corrosion resistance,showing its potential in the field of filtration and separation.

关键词： TiFe2 intermetallic compound porous materials reactive synthesis corrosion behavior hydrogen evolution reaction

Reaction pathways and selectivity in the chemo-catalytic conversion of cellulose and its derivatives to ethylene glycol:A review

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Chinese Journal of Chemical Engineering 2024年第2期66卷 310-331页

作者： yao Li Yuchun Zhang Zhiyu Li Huiyan Zhang Peng Fu College of Agricultural Engineering and Food Science Shandong University of TechnologyZibo 255000China Key Laboratory of Energy Thermal Conversion and Control Ministry of EducationSchool of Energy and EnvironmentSoutheast UniversityNanjing 210096China

Biomass-to-ethylene glycol is an effective means to achieve high-value utilisation of cellulose but is hindered by low conversion efficiency and poor catalyst activity and *** and cellobiose are derivatives of cellulose conversion to ethylene glycol,and it is found that studying the reaction process of both can help to understand the reaction mechanism of *** is desirable to develop a reusable,highly active catalyst to convert cellulose into ethylene *** ideal catalyst might have one or more active sites described the conversion steps ***,we discuss the catalyst development of celluloseto-ethylene glycol,including tungsten,tin,lanthanide,and other transition metal catalysts,and special attention is given to the reaction mechanism and kinetics for preparing ethylene glycol from cellulose,and the economic advantages of biomass-to-ethylene glycol are briefly *** insights given in this review will facilitate further development of efficient catalysts,for addressing the global energy crisis and climate change related to the use of fossil fuels.

关键词： Ethylene glycol Cellulose Catalyst Retro-aldol condensation Hydrolysis Kinetics

Detecting bulk and edge exceptional points in non-Hermitian systems through generalized Petermann factors

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Frontiers of physics 2024年第2期19卷 169-177页

作者： Yue-Yu Zou yao Zhou Li-Mei Chen Peng Ye School of Physics State Key Laboratory of Optoelectronic Materials and Technologiesand Guangdong Provincial Key Laboratory of Magnetoelectric Physics and DevicesSun Yat-sen UniversityGuangzhou 510275China

Non-orthogonality in non-Hermitian quantum systems gives rise to tremendous exotic quantum phenomena,which can be fundamentally traced back to *** this paper,we introduce an interesting quantity(denoted asη)as a new variant of the Petermann factor to directly and efficiently measure non-unitarity and the associated non-Hermitian *** tuning the model parameters of underlying non-Hermitian systems,we find that the discontinuity of bothηand its first-order derivative(denoted as■η)pronouncedly captures rich physics that is fundamentally caused by *** concretely,in the 1D non-Hermitian topological systems,two mutually orthogonal edge states that are respectively localized on two boundaries become non-orthogonal in the vicinity of discontinuity ofηas a function of the model parameter,which is dubbed"edge state transition".Through theoretical analysis,we identify that the appearance of edge state transition indicates the existence of exceptional points(EPs)in topological edge *** the discontinuity of■η,we investigate a two-level non-Hermitian model and establish a connection between the points of discontinuity of■ηand EPs of bulk *** studying this connection in more general lattice models,we find that some models have discontinuity of■η,implying the existence of EPs in bulk states.

关键词： non-Hermitian Su−Schrieffer−Heeger(SSH)model exceptional point