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Mechanism of ultrasonic strengthening fluidity of low mature shale oil: A case study of the first member of Lucaogou Formation, western Jimusaer Sag, Northwest China

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Petroleum Science 2023年第6期20卷 3337-3347页

作者： bo-yang wang bo Liu Yun-Fei Cui Zi-Long wang Key Laboratory of Continental Shale Hydrocarbon Accumulation and Efficient Development Ministry of EducationNortheast Petroleum UniversityDaqing163318HeilongjiangChina No.203 Exploration Team Jilin Bureau of Coalfield GeologySiping136000JilinChina

The low mature shale oil resources of Lucaogou Formation in Jimusar Sag have a great potential, but the heavy oil quality limits large-scale economic development significantly. Ultrasonic is a typical representative of heavy oil viscosity reduction and anhydrous fracturing technology, and how to understand the action characteristics and mechanism of ultrasonic effect on reservoir is a critical issue to enhance shale oil production in the industrialized application of power ultrasonic. Therefore, the comparative experiments with different time of power ultrasonic loading were conducted to analyze the response mechanism of reservoir characteristics and the change of fluid mobility. The results indicate that the ultrasonic treatment is ameliorative to the pore-fracture structure, and the improvement degree is controlled by the mechanical vibration and cavitation of ultrasound. Generally, the location with weak cementation strength or relatively developed microcrack is preferred to pore expansion. After the ultrasonic treatment, the shale oil quality becomes lighter, and the transformation of shale oil from adsorbed to free, is accelerated due to enhanced fluidity. Pore-expanding effect and fluid mobility enhancement are essential aspects of the power ultrasonic loading to improve the recovery of low mature shale oil. The results of this study support the feasibility analysis of ultrasonic enhanced shale oil exploitation theoretically.

关键词： Ultrasonic Shale oil Reservoir properties Mobility Recovery

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Maceral evolution of lacustrine shale and its effects on the development of organic pores during low mature to high mature stage:A case study from the Qingshankou Formation in northern Songliao Basin,northeast China

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Petroleum Science 2023年第5期20卷 2709-2725页

作者： Liu wang bo Liu Long-Hui Bai Mehdi Ostadhassan Thomas Gentzis bo-yang wang Yi-Zhang wang Key Laboratory of Continental Shale Hydrocarbon Accumulation and Efficient Development Ministry of EducationNortheast Petroleum UniversityDaqingHeilongjiang163318China Accumulation and Development of Unconventional Oil and Gas State Key Laboratory Cultivation BaseNortheast Petroleum UniversityDaqingHeilongjiang163318China Core Laboratories Reservoir Geology Group6316 Windfern RoadHoustonTX77040USA Exploration and Development Research Institute of Daqing Oilfield Co Ltd DaqingHeilongjiang163712China

Organic matter(OM)hosted pores are crucial for the storage and migration of petroleum in shale *** maturity and macerals type are important factors controlling the development of pores *** this study,six lacustrine shale samples with different thermal maturities from the first member of the Qingshankou Formation in the Songliao Basin,of which vitrinite reflectance(R_(o))ranging from 0.58% to 1.43%,were selected for a comparative *** electron microscopy(SEM)and reflected light microscopy were combined to investigate the development of organic pores in different macerals during thermal *** results show that alginite and liptodetrinite are the dominant primary macerals,followed by *** a few primary organic pores developed in the alginite at the lowest maturity(R_(o)=0.58%).As a result of petroleum generation,oil-prone macerals began to transform to initial-oil solid bitumen at the early oil window(R_(o)=0.73%)and shrinkage cracks were ***-oil solid bitumen cracked to oil,gas and post-oil bitumen by primary cracking(R_(o)=0.98%).Moreover,solid bitumen(SB)was found to be the dominant OM when R_(o)>0.98%,which indicates that SB is the product of oil-prone macerals *** secondary bubble pores were observed on SB,which formed by gas release,while devolatilization cracks developed on migrated ***,at the late oil window(Ro?1.16%),migrated SB filled the interparticle pore *** further increase in temperature,the liquid oil underwent secondary cracking into pyrobitumen and gas,and spongy pores developed on the pyrobitumen at higher levels of maturity(Ro=1.43%),which formed when pyrobitumen cracked into *** and inertinite are stable without any visible pores over the range of maturities,verifying their low petroleum generation *** addition,it was concluded that clay minerals could have a catalytic effect on the petroleum generation,which may explain why or

关键词： Lacustrine shale Maceral evolution Organic pores Scanning electron microscopy Reflected light microscopy

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Distribution characteristics and oil mobility thresholds in lacustrine shale reservoir:Insights from N_(2)adsorption experiments on samples prior to and following hydrocarbon extraction

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Petroleum Science 2022年第2期19卷 486-497页

作者： Long-Hui Bai bo Liu Yi-Jing Du bo-yang wang Shan-Si Tian Liu wang Zhi-Qiang Xue Accumulation and Development of Unconventional Oil and Gas State Key Laboratory Cultivation BaseNortheast Petroleum UniversityDaqingHeilongjiang 163318China Hubei Key Laboratory of Petroleum Geochemistry and Environment Yangtze UniversityWuhanHubei 430100China Research Institute of Petroleum Exploration&Development Beijing100083China No.1 Institute of Geological and Mineral Resources Survey of Henan LuoyangHenan 471000China

The pore structure and oil content of shales have an important influence on the oil mobility and *** this study,the lacustrine shale samples from the Qingshankou Formation(Q1)of Songliao Basin were ***,pyrolysis,XRD and nitrogen adsorption were performed on the original and extracted shale *** the influence of mineral composition and organic matter(OM)on the development of nano-scale pore,the oil phase states and mobility were *** Q1 shale samples can be sub-divided into three types according to the isotherm *** A samples are characterized by high kerogen content,with oil mainly existing in the free phase *** B samples are characterized by medium kerogen content,oil mainly exists in the absorbed phase *** C samples are characterized by low kerogen content,with trace oil found in the absorbed phase ***-scale organic pores are well developed in the Q1 *** is primarily found in the pore spaces with diameters less than 10 nm,this being the pore size threshold for mobile shale *** TOC>2.0 wt%and EOM>1.0 wt%,Q1 Formation shale oil mobility is high,resulting in prospective drilling targets.

关键词： Shale oil mobility Oil phase state Extraction Nitrogen adsorption

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Deformation measurement by single spherical near-field intensity measurement for large reflector antenna

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Research in Astronomy and Astrophysics 2021年第10期21卷 175-186页

作者： Qian Ye bo-yang wang Qiang Yao Jin-Qing wang Qing-Hui Liu Zhi-Qiang Shen Shanghai Astronomical Observatory Chinese Academy of SciencesShanghai 200030China School of Mechanical Engineering Shanghai Jiao Tong UnversityShanghai 200240China

This paper presents a new method to obtain the deformation distribution on the main reflector of an antenna only by measuring the electric intensity on a spherical surface with the focal point as the center of the sphere,regardless of *** the differential geometry theory with geometric optics method,this paper has derived a deformation-intensity equation to relate the surface deformation to the intensity distribution of a spherical near-field *** on the finite difference method(FDM)and GaussSeidel iteration,deformation has been calculated from intensity simulated by geometrical optics(GO)and physical optics(PO)methods,respectively,with relatively small errors,which prove the effectiveness of the equation proposed in this *** means of this method,it is possible to measure the deformation only by scanning the electric intensity of a single hemispherical near-field whose area is only about 1/15 of the *** measurement only needs a plane wave at any frequency as the incident wave,which means that both the signals from the outer space satellite and the far-field artificial beacon could be used as the *** scanning can be realized no matter what attitude and elevation angle the antenna is in because the size and angle of the hemisphere are changeable.

关键词： telescopes waves line:profiles scattering

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Biological Mechanism of Traditional Chinese Medicine Formula and Herbs in Treating Diseases from the Perspective of Cold and Hot

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World Journal of Traditional Chinese Medicine 2024年第3期10卷 274-283页

作者： bo-yang wang Pan Chen Peng Zhang Shao Li Bioinformatics Division Department of Automation MOE Key Laboratory of Bioinformatics Institute for TCM-X Tsinghua UniversityBNRist

Cold and Hot syndrome, also known as “ZHENG” in Mandarin, is a fundamental theory in traditional Chinese medicine(TCM) and plays a pivotal role in the differentiation of diseases in TCM. Diseases are treated with varying formulas according to the specific syndrome differentiations in TCM. A way of the principles followed in TCM medical strategy is “cold herbs for hot syndrome, and hot herbs for cold syndrome.”Therefore, from the perspective of cold/hot syndrome, we summarizes the present research regarding the characteristics and mechanisms of cold/hot herbs(including herbs with cool and warm properties) in digestive system diseases, respiratory diseases, and autoimmune diseases,among others. As novel technologies have advanced, various methods, such as those based on network target, machine learning, and deep learning, have emerged to reveal the mechanisms underlying cold/hot syndrome and cold/hot herbs. With the help of these technologies, it has been found that cold and hot herbs, as well as formulae with cold or hot intentions, have similarities and differences in the treatment of these diseases. In conclusion, cold and cool may have stronger antibacterial, antiviral, and anti-infiammatory effects, whereas hot and warm herbs may specifically enhance immune regulation. With the assistance of advancing data algorithms, uncovering the mechanisms of cold/hot herbs may accelerate and provide a new research paradigm for further achieving precision in TCM.

关键词： Cold and hot herbs cold and hot syndrome machine learning multi-omics network target traditional Chinese medicine

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Solving Surface Deformation of Radio Telescope Antenna by Artificial Neural Network

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Research in Astronomy and Astrophysics 2022年第3期22卷 194-204页

作者： bo-yang wang Qian Ye Li Fu Guo-Xiang Meng Jin-Qing wang Qing-Hui Liu Zhi-Qiang Shen School of Mechanical Engineering Shanghai Jiaotong UniversityShanghai 200240China Shanghai Astronomical Observatory Chinese Academy of SciencesShanghai 200030China

Recent investigations have derived the relation between the near-field plane amplitude and the surface deformation of reflector antenna,namely deformation-amplitude equation(DAE),which could be used as a mathematical foundation of antenna surface measurement if an effective numerical algorithm is *** algorithms are hard to work directly due to the complex mathematical *** paper presents a local approximation algorithm based on artificial neural network to solve *** length factor method is used to construct a trial solution for the deformation,which ensures the final solution always satisfies the boundary *** improve the algorithm efficiency,Adam optimizer is employed to train the network *** the application of the data normalization method proposed in this paper and a step-based learning rate,a further optimized loss function could be converged *** algorithm proposed in this paper could effectively solve partial differential equations without boundary conditions such as DAE,which at the same time contains the first-order and the second-order partial derivatives,and constant *** results show that compared with the original algorithm by Fast Fourier transform,this algorithm is more stable and accurate,which is significant for the antenna measurement method based on DAE.

关键词： methods:numerical telescopes waves scattering

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Enhanced Sensing Mechanism Based on Shifting an Exceptional Point

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Research 2024年第3期6卷 285-292页

作者： Xuan Mao Guo-Qing Qin Hao Zhang bo-yang wang Dan Long Gui-Qin Li Gui-Lu Long Department of Physics State Key Laboratory of Low-Dimensional Quantum PhysicsTsinghua UniversityBeijing 100084China Beijing Institute of Radio Measurement The Second Academy of China Aerospace Science and Industry Corporation(CASIC)Beijing 100854China Purple Mountain Laboratories Nanjing 21111China Frontier Science Center for Quantum Information Beijing 100084China Beijing Academy of Quantum Information Sciences Beijing 100193China

Non-Hermitian systems associated with exceptional points (EPs) are expected to demonstrate a giant response enhancement for various sensors. The widely investigated enhancement mechanism based on diverging from an EP should destroy the EP and further limits its applications for multiple sensing scenarios in a time sequence. To break the above limit, here, we proposed a new enhanced sensing mechanism based on shifting an EP. Different from the mechanism of diverging from an EP, our scheme is an EP nondemolition and the giant enhancement of response is acquired by a slight shift of the EP along the parameter axis induced by perturbation. The new sensing mechanism can promise the most effective response enhancement for all sensors in the case of multiple sensing in a time sequence. To verify our sensing mechanism, we construct a mass sensor and a gyroscope with concrete physical implementations. Our work will deepen the understanding of EP-based sensing and inspire designing various high-sensitivity sensors in different physical systems.

关键词： mechanism shifting exceptional

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NuMED CHEATHAM-PLATINUM STENT AND BALLOON IN BALLOON DELIVERY CATHETER FOR TREATMENT OF NATIVE COARCTATION OF THE AORTA

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Chinese Medical Sciences Journal 2006年第1期21卷 65-67页

作者： Guang-yi wang bo yang Zhi-feng wang Jun Guo Lu-yue Gai Guang Zhi Department of Cardiology General Hospital of People＇s Liberation Army Beijing 100853

COARCTATION of the aorta (CoA) is a congenital heart defect involving a narrowing of the *** narrowed segment called coarctation is most likely to happen in the segment just after the aortic *** narrowing can be removed by surgery or sometimes by a nonsurgical balloon ***, aortic coarctation may recur even after successful surgery or balloon ***, coarctation can now be treated with nonsurgical balloon dilation associated with implanting a stent using cardiac *** we reported our experience in a 19-year-old boy with CoA who underwent successful covered Cheatham-Platinum (CP) stent implantation for the coarctation.

关键词： covered stent coarctation of the aorta catheter intervention

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AAV2-PDE6B restores retinal structure and function in the retinal degeneration 10 mouse model of retinitis pigmentosa by promoting phototransduction and inhibiting apoptosis

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Neural Regeneration Research 2025年第8期20卷 2408-2419页

作者： Ruiqi Qiu Mingzhu yang Xiuxiu Jin Jingyang Liu Weiping wang Xiaoli Zhang Jinfeng Han bo Lei Henan Eye Hospital Henan Provincial People’s HospitalPeople’s Hospital of Zhengzhou UniversityZhengzhouHenan ProvinceChina Eye Institute Henan Academy of Innovations in Medical ScienceZhengzhouHenan ProvinceChina Branch of National Clinical Research Center for Ocular Disease Henan Provincial People’s HospitalZhengzhouHenan ProvinceChina Academy of Medical Science Zhengzhou UniversityZhengzhouHenan ProvinceChina

Retinitis pigmentosa is a group of inherited diseases that lead to retinal degeneration and photoreceptor cell ***,there is no effective treatment for retinitis pigmentosa caused by PDE6B ***-associated virus(AAV)-mediated gene therapy is a promising strategy for treating retinitis *** aim of this study was to explore the molecular mechanisms by which AAV2-PDE6B rescues retinal *** do this,we injected retinal degeneration 10(rd10)mice subretinally with AAV2-PDE6B and assessed the therapeutic effects on retinal function and structure using dark-and light-adapted electroretinogram,optical coherence tomography,and ***-independent acquisition-mass spectrometry-based proteomic analysis was conducted to investigate protein expression levels and pathway enrichment,and the results from this analysis were verified by real-time polymerase chain reaction and western ***2-PDE6B injection significantly upregulated PDE6βexpression,preserved electroretinogram responses,and preserved outer nuclear layer thickness in rd10 *** expressed proteins between wild-type and rd10 mice were closely related to visual perception,and treating rd10 mice with AAV2-PDE6B restored differentially expressed protein expression to levels similar to those seen in wild-type *** Encyclopedia of Genes and Genome analysis showed that the differentially expressed proteins whose expression was most significantly altered by AAV2-PDE6B injection were enriched in phototransduction ***,the phototransductionrelated proteins Pde6α,Rom1,Rho,Aldh1a1,and Rbp1 exhibited opposite expression patterns in rd10 mice with or without AAV2-PDE6B ***,Bax/Bcl-2,p-ERK/ERK,and p-c-Fos/c-Fos expression levels decreased in rd10 mice following AAV2-PDE6B *** data suggest that AAV2-PDE6B-mediated gene therapy promotes phototransduction and inhibits apoptosis by inhibiting the ERK signaling pathway and upr

关键词： apoptosis AAV2-PDE6B ERK1/2 gene therapy phototransduction proteomics rd10 retinitis pigmentosa

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Experimental demonstration of mode-matching and Sagnac effect in a millimeter-scale wedged resonator gyroscope

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Photonics Research 2022年第9期10卷 2115-2121页

作者： XUAN MAO HONG yang DAN LONG MIN wang PENG-YU WEN YUN-QI HU bo-yang wang GUI-QIN LI JIAN-CUN GAO GUI-LU LONG Department of Physics State Key Laboratory of Low-Dimensional Quantum PhysicsTsinghua UniversityBeijing 100084China Beijing Academy of Quantum Information Sciences Beijing 100193China Frontier Science Center for Quantum Information Beijing 100084China Beijing National Research Center for Information Science and Technology Beijing 100084China School of Information Tsinghua UniversityBeijing 100084China

The highly efficient coupling of light from conventional optical components to optical mode volumes lies in the heart of chip-based micro-devices,which is determined by the mode-matching between propagation constants of fiber taper and the whispering-gallery-mode(WGM)of the *** gyroscopes,typically realized as fiber-optic gyroscopes and ring-laser gyroscopes,have been the mainstay in diverse applications such as positioning and inertial ***,the mode-matching is theoretically analyzed and experimentally *** observe the Sagnac effect in a millimeter-scale wedged resonator gyroscope,which has attracted considerable attention and has been rapidly promoted in recent *** demonstrate a bidirectional pump and probe scheme,which directly measures the frequency beat caused by the Sagnac *** establish the linear response between the detected beat frequency and the rotation *** clockwise and counterclockwise rotation can also be distinguished according to the value of the frequency *** experimental results verify the feasibility of developing the gyroscope in a WGM resonator system and pave the way for future development.

关键词： resonator millimeter pump

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