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Investigation of gravity influence on EOR and CO_(2) geological storage based on pore-scale simulation

Petroleum Science 2024年第2期21卷 987-1001页

作者： Yong-Mao Hao Gui-Cheng Wu Zong-Fa Li Zhong-Hui Wu Yong-Quan Sun Ran Liu xing-xing Li bo-xin pang Nan Li Key Laboratory of Unconventional Oil&Gas Development(China University of Petroleum(East China)) Ministry of EducationQingdao266580ShandongChina School of Petroleum Engineering China University of Petroleum(East China)Qingdao266580ShandongChina School of Petroleum Engineering Yangtze UniversityWuhan430100HubeiChina Dongsheng Jinggong Petroleum Development Group Co. LtdShengli Oilfield CompanySINOPECDongying257001ShandongChina

Gravity assistance is a critical factor influencing CO_(2)-Oil mixing and miscible flow during EOR and CO_(2)geological *** on the Navier-Stokes equation,component mass conservation equation,and fluid property-composition relationship,a mathematical model for pore-scale CO_(2) injection in oilsaturated porous media was developed in this *** model can reflect the effects of gravity assistance,component diffusion,fluid density variation,and velocity change on EOR and CO_(2) *** nonhomogeneous porous media,the gravity influence and large density difference help to minimize the velocity difference between the main flow path and the surrounding area,thus improving the oil recovery and CO_(2) *** CO_(2) injection angles and oil-CO_(2) density differences can increase the oil recovery by 22.6% and 4.2%,respectively,and increase CO_(2) storage by 37.9% and 4.7%,*** diffusion facilitates the transportation of the oil components from the low-velocity region to the main flow path,thereby reducing the oil/CO_(2) concentration difference within the porous *** diffusion can increase oil recovery and CO_(2) storage by 5.7% and 6.9%,*** addition,combined with the component diffusion,a low CO_(2) injection rate creates a more uniform spatial distribution of the oil/CO_(2) component,resulting in increases of 9.5% oil recovery and 15.7% CO_(2) storage,*** study provides theoretical support for improving the geological CO_(2) storage and EOR processes.

关键词： Gravity Flow simulation CO_(2)-oil mixing Enhanced oil recovery(EOR) Geological storage

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Postnatal development of rat retina:a continuous observation and comparison between the organotypic retinal explant model and in vivo development

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Neural Regeneration Research 2025年第3期20卷 900-912页

作者： Baoqi Hu Rui Wang Hanyue Zhang Xiou Wang Sijia Zhou bo Ma Yan Luan xin Wang xinlin Chen Zhichao Zhang Qianyan Kang Department of Ophthalmology The First Affiliated Hospital of Xi’an Jiaotong UniversityXi’anShaanxi ProvinceChina Department of Ophthalmology The First Affiliated Hospital of Northwest UniversityXi’anShaanxi ProvinceChina Institute of Neurobiology Xi’an Jiaotong University Health Science CenterXi’anShaanxi ProvinceChina

The organotypic retinal explant culture has been established for more than a decade and offers a range of unique advantages compared with in vivo experiments and cell ***,the lack of systematic and continuous comparison between in vivo retinal development and the organotypic retinal explant culture makes this model controversial in postnatal retinal development ***,we aimed to verify the feasibility of using this model for postnatal retinal development studies by comparing it with the in vivo *** this study,we showed that postnatal retinal explants undergo normal development,and exhibit a consistent structure and timeline with retinas in ***,we used SOX2 and PAX6 immunostaining to identify retinal progenitor *** then examined cell proliferation and migration by immunostaining with Ki-67 and doublecortin,***-67-and doublecortin-positive cells decreased in both in vivo and explants during postnatal retinogenesis,and exhibited a high degree of similarity in abundance and distribution between ***,we used Ceh-10 homeodomain-containing homolog,glutamate-ammonia ligase(glutamine synthetase),neuronal nuclei,and ionized calcium-binding adapter molecule 1 immunostaining to examine the emergence of bipolar cells,Müller glia,mature neurons,and microglia,*** timing and spatial patterns of the emergence of these cell types were remarkably consistent between in vivo and explant *** study showed that the organotypic retinal explant culture model had a high degree of consistency with the progression of in vivo early postnatal retina *** findings confirm the accuracy and credibility of this model and support its use for long-term,systematic,and continuous observation.

关键词： bipolar cells differentiation in vivo microglia Müller glia organotypic retinal explant culture postnatal retina development proliferation retinal progenitor cells

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The Establishment and Application of a Kraken Classifier for Salmonella Plasmid Sequence Prediction

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China CDC weekly 2022年第49期4卷 1110-1116页

作者： Zhenpeng Li bo pang xin Lu Biao Kan State Key Laboratory of Infectious Disease Prevention and Control National Institute for Communicable Disease Control and PreventionChinese Center for Disease Control and PreventionBeijing MunicipalityChina School of Public Health Shandong UniversityJinan CityChina.

Introduction:Salmonella is a key intestinal pathogen of foodborne disease,and the plasmids in Salmonella are related to many biological characteristics,including virulence and drug resistance.A large number of plasmid contigs have been sequenced in bacterial draft genomes,however,these are often difficult to distinguish from chromosomal ***:In this study,three different customized Kraken databases were used to build three different Kraken *** genome benchmark datasets and simulated draft genome benchmark datasets were ***-fold cross-validation was used to evaluate the performance of the three different Kraken classifiers by two benchmark ***:The predictive performance of the classifier based on all National Center for Biotechnology Information plasmids and Salmonella complete genomes was *** optimal Kraken classifier was performed with Salmonella isolated in *** plasmid carrying rate of Salmonella in China is 91.01%,and it was found that the Kraken classifier could find more plasmid contigs and antibiotic resistance genes(ARGs)than results derived from a plasmid replicon-based method(PlasmidFinder).Moreover,it was found that in the strains carrying ARGs,plasmids carried more ARGs[three,95%confidence interval(CI):1–14]than chromosomes(one,95%CI:1–7).Discussion:We found building a high-quality customized database as a Kraken classifier to be ideal for the prediction of Salmonella plasmid sequences from bacterial draft *** the future,the Kraken classifier established in this study will play a significant role in ARG monitoring.

关键词： classifier database Application

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(K_(0.5)Na_(0.5))Nb_(1-x)Ta_(x)O_(3)铁电性的第一性原理研究

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原子与分子物理学报 2025年第4期42卷 138-146页

作者：褚新建雷博程刘晨曦刘纪博新疆科技学院信息科学与工程学院库尔勒841000 新疆大学物理科学与技术学院新疆固体物理与器件重点实验室乌鲁木齐830046 西安工业大学光电工程学院西安710032

随着铅基陶瓷的大量使用,造成了严重的环境和健康问题,为了能够找寻替代铅基陶瓷的材料,人们开始了对无铅陶瓷材料的探索.(K_(0.5)Na_(0.5))Nbo_(3)材料由于其优异的铁电压电性能,成为了无铅陶瓷材料的代表,但是碱性组分在高温下的高挥... 详细信息

随着铅基陶瓷的大量使用,造成了严重的环境和健康问题,为了能够找寻替代铅基陶瓷的材料,人们开始了对无铅陶瓷材料的探索.(K_(0.5)Na_(0.5))Nbo_(3)材料由于其优异的铁电压电性能,成为了无铅陶瓷材料的代表,但是碱性组分在高温下的高挥发性使其应用范围受到了极大的限制.基于这样的考虑,本文基于密度泛函理论的第一性原理方法,探究了(K_(0.5)Na_(0.5))Nb_(1-x)TaxO_(3)(x=0.125,0.25,0.375,0.5,0.625,0.75,0.875,1)九种体系的铁电性能,结果表明:随着Ta浓度的增加,晶格常数发生了突变,由此猜测KNN材料随着Ta浓度的增加,发生了正交-单斜的相变;Ta的掺入能够降低KNN材料的烧结难度,且随着Ta浓度的增加,形成难度逐渐降低;掺杂体系中,Ta-4f轨道与Na-3p,K-4p以及O-2s轨道电子发生了杂化,使导带底Nb-4d与Na-3p电子的态密度峰向高能区移动,禁带宽度呈现增加的趋势;在分析KNN材料铁电性作用机理时发现KNN的铁电极化类型是离子位移型极化,且在[001]方向上不具有极化能力.分析掺杂后各个体系的极化强度,发现随着Ta浓度的增加,极化强度逐渐降低,但是在低浓度掺杂时极化有向上增加的趋势,这可能是体系在低浓存在着正交与单斜的准同型相界(Morphotropic phase boundary,MPB)导致的,由此可以判断,低浓度掺杂有利于提高KNN材料的铁电性能.

关键词：第一性原理钙钛矿结果 KNN 铁电性

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Surface modifications of layered LiNi_(x)Mn_(y)Co_(z)O_(2)cathodes via atomic and molecular layer deposition

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Rare Metals 2023年第7期42卷 2121-2156页

作者： xin Wang Xiang-bo Meng Department of Mechanical Engineering University of ArkansasFayettevilleAR72701USA

Currently,there has an ever-growing interest in layered LiNi_(x)Mn_(y)Co_(z)O_(2)(NMCs,x+y+z=1)cathode materials for lithium-ion batteries(LIBs)and lithium metal batteries(LMBs),due to their low cost and high ***,they still suffer from a series of issues,such as Li/Ni cation mixing,irreversible phase transition,and transition metal *** issues result in severe capacity degradation and limited cyclability of ***,atomic and molecular layer deposition(ALD and MLD)have emerged as a novel tool to tackle these issues,featuring their unique capabilities to fine-tailor NMCs'surfaces for stable interfaces and improved electrochemical performance in LIBs and *** this review,we specially summarize the recent advances of different ALD and MLD coatings on NMCs and discuss their working *** expect that this review will stimulate more efforts to further develop better NMCs using novel ALD/MLD coatings.

关键词： Lithium-ion batteries(LIBs) Lithium metal batteries(LMBs) NMC cathodes Atomic layer deposition(ALD) Molecular layer deposition(MLD) Surface coating

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Mechanism of action of Linggui Zhugan Decoction in treating non-alcoholic fatty liver disease using untargeted metabolomics approach

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Traditional Medicine Research 2025年第2期10卷 65-76页

作者： Huan Pei Ren-Lin Li xin-Ran Song Qian-Qian Wan Yu-Ming Wang Han-Zhou Li Wei-Quan Xu Jia-Bao Liao Wei-bo Wen Jing Miao Huan-Tian Cui School of Basic Medicine Yunnan University of Chinese MedicineKunming 650599China School Clinical Medical College Yunnan University of Chinese MedicineKunming 650599China First School of Clinical Medicine Yunnan University of Chinese MedicineKunming 650599China School of Integrative Chinese and Western Medicine Tianjin University of Traditional Chinese MedicineTianjin 301617China Department of Pharmacy Tianjin Second People's HospitalTianjin 300192China

Background:Non-alcoholic fatty liver disease(NAFLD)is a liver disorder characterized by the accumulation and degeneration of fat in the liver cells,a condition that may further deteriorate and lead to cirrhosis and liver *** studies showed that metabolic dysfunction can promote NAFLD *** Zhugan Decoction(LGZGD)has therapeutic effects on *** mechanism of LGZGD still remains *** study was to examine the impact of LGZGD on the metabolic processes involved in the development of ***:A mice model of NAFLD was treated with *** therapeutic potential of LGZGD was evaluated by assessing the activity of transaminases,lipids levels of blood,and pathological changes in the liver of the mice model of ***,this study also evaluated the influence of LGZGD on liver inflammation and oxidative ***:The results of untargeted metabolomics analysis showed that LGZGD reduced the disordered lipid metabolism in NAFLD *** improved the oxidative stress and also reduced the levels of pro-inflammatory cytokines in the *** metabolomics analysis of liver samples revealed that LGZGD treatment improved metabolic disorders,including alanine,aspartate,glutamate,glycerophospholipid metabolism,and citrate *** RT-qPCR and Western blot results showed that LGZGD could regulate the expression of key enzymes in the metabolic pathway of the citrate cycle,including ATP-citrate lyase(ACLY),alanine-glyoxylate aminotransferase-2(AGXT2),phosphatidylethanolamine N-methyltransferase(PEMT),and succinate dehydrogenase(SDH).Conclusion:We found that LGZGD can treat NAFLD by reducing inflammatory responses,inhibiting oxidative stress,regulating alanine,aspartate,glutamate,and glycerophospholipid metabolism,and citrate cycle pathways.

关键词： NAFLD LGZGD untargeted metabolomics glycerophospholipid metabolism citrate cycle

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瞬变电磁探测技术在小纪汗煤矿的应用与研究

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价值工程 2025年第1期44卷 99-101页

作者：薄涛崔鑫磊陕西华电榆横煤电有限责任公司榆林719015 中国矿业大学(北京) 北京100083

煤炭作为我国国民经济的重要支柱,其深部开采面临复杂多变的地层特征,包括高地应力、构造应力变化及梯度差异,导致井下环境充满危险因素,水害尤为突出。瞬变电磁探测技术在近20年来取得显著进步,成为煤矿防治水工作的关键手段。本研究... 详细信息

煤炭作为我国国民经济的重要支柱,其深部开采面临复杂多变的地层特征,包括高地应力、构造应力变化及梯度差异,导致井下环境充满危险因素,水害尤为突出。瞬变电磁探测技术在近20年来取得显著进步,成为煤矿防治水工作的关键手段。本研究采用矿井瞬变电磁法,针对小纪汗煤矿特定煤层区域,详细探查了煤层顶底板含水情况。通过对瞬变电磁视电阻率数据的综合分析,我们成功绘制了等值线断面图和平面图,进而进行了地质推断,明确了煤层与上下含水层的分布情况。研究结果显示,煤矿充水强度较大,主要水源为顶板砂岩裂隙承压水。瞬变电磁法的应用,不仅精确界定了顶底板承压水聚集区,还为矿井开采与疏放水工程的科学布置提供了坚实依据,展现了该技术在实际应用中的高效与准确性。

关键词：瞬变电磁探测井下物探超前探测顶板承压水

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Characteristics and origin of low-organicmatter carbonate source rocks in the Middle-Upper Ordovician, Tarim Basin, northwestern China

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Journal of Palaeogeography 2024年第3期13卷 594-619页

作者： Jun-Qing Chen Fu-Jie Jiang Xiong-Qi pang Hai-Jun Yang Kan-Yuan Shi bo pang Hong pang Jian-Fa Chen Zhuo-Heng Chen xin-Gang Zhang Song Wu State Key Laboratory of Petroleum Resources and Engineering China University of Petroleum(Beijing)Beijing 102249China Basic Research Center for Energy Interdisciplinary College of ScienceChina University of Petroleum(Beijing)Beijing 102249China Beijing Key Laboratory of Optical Detection Technology for Oil and Gas China University of Petroleum(Beijing)Beijing 102249China College of Geosciences China University of Petroleum(Beijing)Beijing 102249China Research Institute of Petroleum Exploration and Development PetroChina Tarim Oilfield CompanyKorla 841000Xinjiang Uygur Autonomous RegionChina Geological Survey of Canada Natural Resources CanadaCalgary T2L 2A7Canada

The continually-discovered large volumes of marine hydrocarbons indicate a huge exploration potential within the carbonate rocks of Ordovician in the Tarim Basin,northwestern *** Middle-Upper Ordovician(O2+3)carbonate source rocks are at a highly mature *** rocks presently contain a low amount of total organic carbon(TOC_(pd)≤0.5%)(TOC_(pd) means the present-day TOC).A mass balance approach is used to identify the source rocks that have expelled *** characteristics and origin of hydrocarbon expulsion from low-TOC_(pd) source rocks are studied,which are significant for oil exploration in the *** results showed that a low-TOC_(pd) O2+3 source rock having expelled hydrocarbons was type I and had a very narrow oil *** a high rock maturity and a high original TOC(TOCo)value exceeding 1%,nearly 80%of the generated hydrocarbons were *** content of gammacerane and C28 steranes in the oil and source rock extracts were relatively lean,with a V-shaped distribution of regular steranes,suggesting a possible genetic relation between the low-TOC_(pd) source rocks and the marine oil in the Tabei *** planktonic algae or acritarchs were the main hydrocarbon parent materials,distributed in the subsiding platform-slope *** matter was preserved under reducing conditions,and source rocks were formed with a favorable kerogen type and a moderate hydrocarbon generation *** study illustrates the hydrocarbon expulsion of low TOC_(pd) source rocks in northern Tarim Basin,which is greatly significant for analyzing the genesis of marine crude oil in Tarim Basin,and evaluating the distribution of marine source *** research method is theoretically significant for oil and gas exploration in the same type of highlymature carbonate paleobasins.

关键词： Carbonate source rock Mass balance approach Present-day TOC Genesis mechanism Tarim Basin

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The Darboux Transformation and New Explicit Solutions for the Belov–Chaltikian Lattice

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Chinese Physics Letters 2012年第10期29卷 1-4页

作者： XUE bo WANG xin Department of Mathematics Zhengzhou UniversityZhengzhou 450001

An N-fold Darboux transformation with multi-parameters for the famous Belov–Chaltikian lattice is derived with the aid of the gauge transformation between the corresponding discrete 3×3 matrix *** using the Darboux transformation and the reduction technique,new multi-soliton solutions for the Belov–Chaltikian lattice,which are proved to be of solitary features,are given in the exponential form.

关键词： spectra form Darboux

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Forecast for weighing neutrinos in cosmology with SKA

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Science China(Physics,Mechanics & Astronomy) 2020年第8期63卷 53-60页

作者： Jing-Fei Zhang bo Wang xin Zhang Department of Physics College of SciencesNortheastern UniversityShenyang 110819China Ministry of Education’s Key Laboratory of Data Analytics and Optimization for Smart Industry Northeastern UniversityShenyang 110819China Center for High Energy Physics Peking UniversityBeijing 100080China

We investigate what role the SKA neutral hydrogen(HI)intensity mapping(IM)and galaxy sky surveys will play in weighing neutrinos in *** use the simulated data of the baryon acoustic oscillation(BAO)measurements from the HI surveys based on SKA1(IM)and SKA2(galaxy)to do the *** the current observations,we use the Planck 2015 cosmic microwave background(CMB)anisotropies observation,the optical BAO measurements,the type Ia supernovae(SN)observation(Pantheon compilation),and the latest H0 *** consider three mass ordering cases for massive neutrinos,i.e.,the normal hierarchy(NH),inverted hierarchy(IH),and degenerate hierarchy(DH)*** is found that the SKA observation can significantly improve the constraints on?m and *** to the current observation,the SKA1 data can improve the constraints on?m by about 33%,and on H0 by about 36%;the SKA2 data can improve the constraints on?m by about 58%,and on H0 by about 66%.It is also found that the SKA observation can only slightly improve the constraints on∑mν.Compared to the current observation,the SKA1 data can improve the constraints on∑mνby about 4%,3%,and 10%,for the NH,IH,and DH cases,respectively;the SKA2 data can improve the constraints on∑mνby about 7%,7%,and 16%,for the NH,IH,and DH cases,respectively.

关键词： 21 cm observation intensity mapping survey Square Kilometre Array baryon acoustic oscillations neutrino mass

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