检索结果-南通市图书馆

Endoscopic and clinicopathologic characteristics of early gastric cancer with high microsatellite instability

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2012年第27期18卷 3571-3577页

作者： Jaehoon Jahng young Hoon youn Kwang Hyun Kim Junghwan Yu Yong Chan Lee Woo Jin Hyung Sung Hoon Noh Hyunki Kim Hoguen Kim Hyojin Park Sang In Lee Department of Internal Medicine Gangnam Severance HospitalYonsei University College of MedicineSeoul 135-720South Korea Department of Internal Medicine Institute of GastroenterologyYonsei University College of MedicineSeoul 100-753South Korea Department of Surgery Yonsei University College of MedicineSeoul 100-753South Korea Department of Pathology Yonsei University College of MedicineSeoul 100-753South Korea

AIM： To investigate endoscopic and clinicopathologic characteristics of early gastric cancer （EGC） according to microsatellite instability phenotype. METHODS： Data were retrospectively collected from a single tertiary referral center. Of 981 EGC patients surgically treated between December 2003 and October 2007, 73 consecutive EGC patients with two or more microsatellite instability （MSI） mutation [high MSI （MSI-H）] and 146 consecutive EGC patients with one or no MSI mutation （non-MSI-H） were selected. The endoscopic and clinicopathologic features were compared between the MSI-H and non-MSI-H EGC ***： In terms of endoscopic characteristics, MSI-H EGCs more frequently presented with elevated pattern （OR 4.38, 95% Cl： 2.40-8.01, P 〈 0.001）, moderate- to-severe atrophy in the surrounding mucosa （OR 1.91, 95% CI： 1.05-3.47, P = 0.033）, antral location （OR 3.99, 95% CI： 2.12-7.52, P 〈 0.001） and synchronous le- sions, compared to non-MSI-H EGCs （OR 2.65, 95% CI： 1.16-6.07, P = 0.021）. Other significant clinicopatholog- ic characteristics of MSI-H EGC included predominance of female sex （OR 2.77, 95% CI： 1.53-4.99, P 〈 0.001）, older age （〉 70 years）（OR 3.30, 95% CI： 1.57-6.92, P = 0.002）, better histologic differentiation （OR 2.35, 95% Cl： 1.27-4.34, P = 0.007）, intestinal type by Lau- ren classification （OR 2.34, 95% CI： 1.15-4.76, P = 0.019）, absence of a signet ring cell component （OR 2.44, 95% CI： 1.02-5.86, P = 0.046）, presence of mu- cinous component （OR 5.06, 95% Cl： 1.27-20.17, P = 0.022）, moderate-to-severe lymphoid stromal reaction （OR 3.95, 95% CI： 1.59-9.80, P = 0.003）, and co-exist- ing underlying adenoma （OR 2.66, 95% CI： 1.43-4.95, P = 0.002）. CONCLUSION： MSI-H EGC is associated with unique endoscopic and clinicopathologic characteristics includ- ing frequent presentation in protruded type, co-exist- ing underlying adenoma, and synchronous lesions.

关键词： Microsatellite instability Early gastric can-cer Endoscopic characteristic Advanced gastric cancer

Endoscopic removal of gastric ectopic pancreas:An initial experience with endoscopic submucosal dissection

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2010年第36期16卷 4589-4593页

作者： Dong Yup Ryu Gwang Ha Kim Do youn Park bong Eun Lee Jae Hoon Cheong Dong Uk Kim Hyun young Woo Jeong Heo Geun Am Song Department of Internal Medicine Pusan National University School of Medicine and Medical Research InstitutePusan National University HospitalBusan 602-739South Korea Department of Pathology Pusan National University School of MedicineBusan 602-739South Korea

AIM:To evaluate the therapeutic usefulness and safety of endoscopic resection in patients with gastric ectopic ***:A total of eight patients with ectopic pancreas were *** of them underwent endoscopic ultrasonography before endoscopic ***-scopic resection was performed by two methods:endo-scopic mucosal resection(EMR)by the injection-and-cut technique or endoscopic mucosal dissection(ESD).RESULTS:We planned to perform EMR in all eight cases but EMR was successful in only four *** the other four cases,saline spread into surrounding normal tissues and the lesions becameattened,which made it impossible to remove them by *** four cases,we performed ESD and removed the lesions without any ***:If conventional EMR is difficult to remove gastric ectopic pancreas,ESD is a feasible alternative method for successful removal.

关键词： Ectopic pancreas Endoscopic resection Endoscopic ultrasonography

Hierarchical Ti_(3)C_(2)T_(x)@ ZnO Hollow Spheres with Excellent Microwave Absorption Inspired by the Visual Phenomenon of Eyeless Urchins

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano-Micro Letters 2022年第5期14卷 62-76页

作者： Yan‑Qin Wang Hai‑bo Zhao Jin‑bo Cheng bo‑Wen Liu Qiang Fu Yu‑Zhong Wang Collaborative Innovation Center for Eco‑Friendly and Fire‑Safety Polymeric Materials(MoE) State Key Laboratory of Polymer Materials EngineeringNational Engineering Laboratory for Eco‑Friendly Polymer Materials(Sichuan)College of ChemistrySichuan UniversityChengdu 610064People’s Republic of China College of Polymer Science and Engineering State Key Laboratory of Polymer Materials EngineeringSichuan UniversityChengdu 610065People’s Republic of China

Ingenious microstructure design and rational composition selection are effective approaches to realize high-performance microwave absorbers,and the advancement of biomimetic manufacturing provides a new *** nature,urchins are the animals without eyes but can“see”,because their special structure composed of regular spines and spherical photosensitive bodies“amplifies”the light-receiving ***,inspired by the above phenomenon,the biomimetic urchin-like Ti_(3)C_(2)T_(x)@ZnO hollow microspheres are rationally designed and fabricated,in which ZnO nanoarrays(length:~2.3μm,diameter:~100 nm)as the urchin spines are evenly grafted onto the surface of the Ti_(3)C_(2)T_(x) hollow spheres(diameter:~4.2μm)as the urchin spherical photosensitive *** construction of gradient impedance and hierarchical heterostructures enhance the attenuation of incident electromagnetic *** the EMW loss behavior is further revealed by limited integral simulation calculations,which fully highlights the advantages of the urchin-like *** a result,the Ti_(3)C_(2)T_(x)@ZnO hollow spheres deliver a strong reflection loss of−57.4 dB and broad effective absorption bandwidth of 6.56 GHz,superior to similar *** work provides a new biomimetic strategy for the design and manufacturing of advanced microwave absorbers.

关键词： Bioinspired Hierarchical heterostructures Ti_(3)C_(2)T_(x)MXene ZnO nanoarrays Microwave absorption

Effects of different flui replacements on serum HSP70 and lymphocyte DNA damage in college athletes during exercise at high ambient temperatures

在线全文

学校读者我要写书评

暂无评论

Journal of Sport and Health Science 2016年第4期5卷 448-455页

作者： Hee-Tae Roh Su-youn Cho Wi-young So Il-young Paik Sang-Hoon Suh Department of Physical Education Dong-A University Exercise Physiology Laboratory Department of Physical EducationYonsei University Sports and Health Care Major College of Humanities and ArtsKorea National University of Transportation

Purpose：The aim of this study was to investigate the effects of flui replacement by water or sports drinks on serum heat shock protein 70（HSP70） levels and DNA damage during exercise at a high ambient ***：Ten male college athletes with an athletic career ranging from 6 to 11 years were recruited from Yonsei *** subjects ran on a treadmill at 75% of heart rate reserve during 4 different trials：thermoneutral temperature at 18℃（T）,high ambient temperature at 32℃ without flui replacement（H）,high ambient temperature at 32℃ with water replacement（HW）,and high ambient temperature at 32℃ with sports drink replacement（HS）.During each condition,blood samples were collected at the pre-exercise baseline（PEB）,immediately after exercise（IAE）,and60 min ***：Skin temperature significant y increased during exercise and was significant y higher in H compared to T and HS at ***,serum HSP70 was significant y increased in all conditions at IAE compared to PEB and was higher in H compared to T at the former time *** y increased lymphocyte DNA damage（DNA in the tail,tail length,tail moment） was observed in all trials at IAE compared to PEB,and attenuated DNA damage（tail moment） was observed in HS compared to H at ***：Acute exercise elevates serum HSP70 and induces lymphocyte DNA *** replacement by sports drink during exercise at high ambient temperature can attenuate HSP response and DNA damage by preventing dehydration and reducing thermal stress.

关键词： Acute exercise DNA damage Fluid replacement Heat stress HSP70 Sports drink

Preparation of Macroscopic Quantum Superposition States of Cavity Modes Using rf-SQUIDs in a Cavity

在线全文

学校读者我要写书评

暂无评论

Communications in Theoretical Physics 2008年第6期49卷 1599-1602页

作者： WANG bo State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics Wuhan Institute of Physics and Mathematics the Chinese Academy of Sciences Wuhan 430071 China

We propose a potential scheme of preparing Schrodinger-cat state of the cavity mode by placing an rfsuperconducting quantum interference device （rf-SQUID） in a single-mode microwave cavity. By properly adjusting the detuning and the strength regarding the radiation fields, we show how to generate single-mode Schrodinger-cat state. Generalizing this method we discuss the generation of the engtangled coherent states. The experimental feasibility of our scheme is discussed under consideration of the cavity decay.

关键词： SchrSdinger-cat states rf-SQUID cavity

Comparison of litterfall production in three forest types in Jeju Island, South Korea

在线全文

学校读者我要写书评

暂无评论

Journal of Forestry Research 2020年第3期31卷 945-952页

作者： Ji young An Si Ho Han Woo Bin youn Sang Ick Lee Afroja Rahman Huong Thi Thuy Dao Jeong Min Seo Aung Aung Hyung-Soon Choi Hwa Ja Hyun Byung Bae Park Department of Natural Resources Kyoto UniversityKyoto 606-8502Japan Department of Environment and Forest Resources Chungnam National UniversityDaejeon 34134Republic of Korea Forest Environment Conservation Division Korea Forest ServiceDaejeon 35208Republic of Korea Forest Conservation Department National Institute of Forest ScienceSeoul 02455Republic of Korea Warm Temperate and Subtropical Forest Research Center National Institute of Forest ScienceSeogwipo 63582Republic of Korea

Litterfall, which is influenced by physical and biological factors, is a major pathway for carbon and nutrient cycling in forest ecosystems. The purpose of this study was to investigate monthly litterfall production in three forests in Jeju Island differentiated by forest composition and precipitation: Cheongsu(Quercus glauca as the dominant species;low precipitation), Seonheulb(Q. glauca as the dominant species;high precipitation), and Seonheulm(Q. glauca and Pinus thunbergii as the dominant species;high precipitation). Litterfall was collected monthly from April to December 2015 and divided into leaf litter, twig, bark, seeds, and unidentified *** patterns of litterfall production varied across stands according to their species composition. However,the amount of leaf litterfall and total litterfall were comparable among stands, ranging from 362 to 375 g m-2 for leaf litter and 524 g m-2 to 580 g m-2 for total *** leaf litter in May was the highest in all stands, while needle litter was the highest in December in *** twig litterfall in July may be attributable to high rainfall with strong winds and storms during the rainy season. Although forest type and climate factor had no influence on litterfall amounts in this study, the pattern of litterfall production was species dependent, suggesting diverse effects on carbon and nutrient cycling in these forests.

关键词： Coniferous forest Evergreen broadleaved forest Gotjawal Leaf litter Precipitation Temperature

Gut microbiota as a potential key to modulating humoral immunogenicity of new platform COVID-19 vaccines

在线全文

学校读者我要写书评

暂无评论

Signal Transduction and Targeted Therapy 2023年第6期8卷 2447-2450页

作者： Hye Seong bo Kyu Choi young-Hee Han Jun Hyoung Kim Jeong-An Gim Sooyeon Lim Ji Yun Noh Hee Jin Cheong Woo Joo Kim Joon young Song Department of Internal Medicine Korea University College of MedicineSeoulRepublic of Korea Asia Pacific Influenza Institute Korea University College of MedicineSeoulRepublic of Korea Vaccine Innovation Center Korea University College of MedicineSeoulRepublic of Korea Department of Biomedical Systems Informatics Yonsei University College of MedicineSeoulRepublic of Korea Department of Food and Nutrition Chungbuk National UniversityCheongjuRepublic of Korea Department of Internal Medicine Chungbuk National University HospitalCheongjuRepublic of Korea Medical Science Research Center Korea University College of MedicineSeoulRepublic of Korea

Dear Editor,Coronavirus disease 2019(COVID-19)is a novel respiratory infectious disease,caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),which led to a global *** vaccination is the best measure to overcome a pandemic,the immunogenicity of vaccines can be influenced by diverse factors,including intrinsic(age,sex,genetics,and comorbidities),extrinsic(diet,nutrition,and behavior),and vaccine-associated characteristics.

关键词： vaccines respiratory acute

Numerical Analysis of a Gravity Substructure for 5 MW Offshore Wind Turbines Due to Soil Conditions

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Energy and Power Engineering 2016年第3期10卷 150-158页

作者： Min-Su Park youn-Ju Jeong young-Jun You Structural Engineering Research Institute Korea Institute of Civil Engineering and Building Technology Goyang-Si 10223South Korea

In order to increase the gross generation of wind turbines, the size of a tower and a rotor-nacelle becomes larger. In other words, the substructure for offshore wind turbines is strongly influenced by the effect of wave forces as the size of substructure increases. In addition, since a large offshore wind turbine has a heavy dead load, the reaction forces on the substructure become severe, thus very firm foundations should be required. Therefore, the dynamic soil-structure interaction has to be fully considered and the wave forces acting on substructure accurately calculated. In the present study, ANSYS AQWA is used to evaluate the wave forces. Moreover, the substructure method is applied to evaluate the effect of soil-structure interaction. Using the wave forces and the stiffness and damping matrices obtained from this study, the structural analysis of the gravity substructure is carried out through ANSYS mechanical. The structural behaviors of the strength and deformation are evaluated to investigate an ultimate structural safety and serviceability of gravity substructure for various soil conditions. Also, the modal analysis is carried out to investigate the resonance between the wind turbine and the gravity substructure.

关键词： Offshore wind energy gravity substructure suction bucket foundation substructure method structural analysis.

Risk of gastric cancer is associated with PRKAA1 gene polymorphisms in Koreans

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2014年第26期20卷 8592-8598页

作者： Yong-Dae Kim Dong-Hyuk Yim Sang-Yong Eom Sun In Moon Hyo-Yung Yun young-Jin Song Sei-Jin youn Taisun Hyun Joo-Seung Park Byung Sik Kim Jong-young Lee Hee Kwan Won Heon Kim Department of Preventive Medicine College of MedicineChungbuk National University Department of Surgery College of MedicineChungbuk National University Department of Internal Medicine College of MedicineChungbuk National University Department of Food and Nutrition Chungbuk National University Department of Surgery College of MedicineEulji University Department of Surgery Asan Medical CenterCollege of MedicineUlsan University Center for Genome Science National Institute of Health Department of Internal Medicine Division of Endocrinology and MetabolismSchool of MedicineKonyang University

AIM: To evaluate the association between genetic polymorphisms of the gene encoding AMP-activated protein kinase (PRKAA1) and the risk of gastric cancer.

关键词： AMP-activated protein kinase Gastric cancer PRKAA1 Single nucleotide polymorphism Case-control study