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Mast Cell-Derived Exosomes at the Stimulated Acupoints Activating the Neuro-immune Regulation

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Chinese Journal of Integrative Medicine 2017年第11期23卷 878-880页

作者： CHEN bo LI ming-yue guo Yi ZHAO Xue LIM Hui-min Calista Acu-moxibustion and Tuina Department of Tianjin University of Traditional Chinese Medicine Tianjin(300193)China Department of Clinical Practice Teaching Tianjin University of Traditional Chinese MedicineTianjin(300193)China

Exosomes are cell-derived vesicles that take part in intercellular signaling. Research has shown that acupuncture is closely related to affecting the functions of the mast cells in the local region of the acupoint, and stimulating the afferent nerve. Mast cells have a connection with the conduction within the meridians, and play an important role in immuno-regulation. The ＇synapse-like＇ connection between the mast cells and nerve endings is the basis for the exchange of information between these two tissues. Exosome mediates mast exchange of information between mast cells and the nerves, starting the process of neuro-immuno regulation. Therefore, we propose that mast cell-derived exosomes mediate the neuro-immuno regulation at the local site of acupuncture, and this is one of the key factors resulting in the effectiveness of acupuncture.

关键词： mast cell-derived exosomes acupuncture neuro-immuno regulation

Local time and Tanaka formula of G-martingales

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Applied Mathematics(A Journal of Chinese Universities) 2019年第4期34卷 468-479页

作者： LIU guo-min School of Mathematical Sciences Fudan University

The objective of this paper is to study the local time and Tanaka formula of symmetric *** introduce the local time of G-martingales and show that it belongs to the G-expectation space LG^2(ΩT).By a localization argument,we obtain the bicontinuous modification of local ***,we give the Tanaka formula for convex functions of G-martingales.

关键词： G-martingale Local time Tanaka formula

Investigating the role of Ca^(2+)/calmodulin-dependent protein kinaseⅡin the survival of retinal ganglion cells

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Neural Regeneration Research 2022年第5期17卷 1001-1002页

作者： Xinzheng guo bo Chen Departments of Ophthalmology and Neuroscience Icahn School of Medicine at Mount SinaiNew YorkNYUSA

Retinal ganglion cells(RGCs)are the sole output neurons of the retina that project long axons and transmit visual information to the *** degeneration of RGCs leads to irreversible vision loss in a variety of pathologi... 详细信息

关键词： degeneration glaucoma irreversible

降雨诱发国道G326顺层滑坡破坏与运动过程研究

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三峡大学学报（自然科学版） 2025年第1期47卷 44-49页

作者：刘仕洪宋琨郭磊曹俊姜波贵州省铜仁公路管理局贵州铜仁554200 三峡大学防灾减灾湖北省重点实验室湖北宜昌443002 贵州省交通规划勘察设计研究院股份有限公司贵阳550081

贵州省国道G326松桃县甘龙镇石板村田堡组顺层滑坡是2020年强降雨诱发的滑坡灾害.在对滑坡变形破坏特征调查的基础上,分析了强降雨诱发滑坡滑动破坏的成因.采用物质点法(materialpointmethod,MPM)进行了滑坡运动过程的模拟,揭示了滑坡... 详细信息

贵州省国道G326松桃县甘龙镇石板村田堡组顺层滑坡是2020年强降雨诱发的滑坡灾害.在对滑坡变形破坏特征调查的基础上,分析了强降雨诱发滑坡滑动破坏的成因.采用物质点法(materialpointmethod,MPM)进行了滑坡运动过程的模拟,揭示了滑坡运动的速度和冲击荷载等变化规律.结果表明:国道G326滑坡是受2020年7月8日的强降雨诱发的中型顺层岩质滑坡,在8日4时的小时降雨量为96.2mm后约3h发生整体滑移破坏;物质点法能够较真实地模拟滑坡的运动、堆积过程,模拟的堆积体形态与滑坡破坏调查情况基本一致;滑坡岩土体的最大滑动速度为27m/s,最大滑动动能为1.8×109J(15s左右),最大冲击力为37.98×106kN,位于距滑坡后缘约230m处.该研究对国道G326沿线类似滑坡灾害的风险防控具有参考价值和工程借鉴意义.

关键词：降雨滑坡顺层滑动运动过程模拟物质点法冲击荷载

Systematic analysis of microfauna indicator values for treatment performance in a full-scale municipalwastewater treatment plant

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Journal of Environmental Sciences 2013年第7期25卷 1379-1385页

作者： bo Hu Rong Qi min Yang State Key Laboratory of Environmental Aquatic Chemistry Research Center for Eco-Environmental Sciences Chinese Academy of Sciences

The indicator values of microfauna functional groups and species for treatment performancewere systematically evaluated based on the continuous monitoring of the entire microfauna communities including both protozoa and metazoa over a period of 14 months, in two parallel full-scale municipalwastewater treatment systems in a plant in Beijing, China. A total of 57 species of ciliates, 14 species （units） of amoebae, 14 species （units） of flagellates and4 classes of small metazoawere identified,with Arcella hemisphaerica, Vorticella striata, Vorticella convallaria, Epistylis plicatilis and small flagellates （e.g. bodo spp.） as thedominant protozoa, and rotifers as thedominant metazoa. The abundance of the sessile ciliateswas correlatedwith the removals of boD 5 （Pearson＇s r = 0.410, p 〈 0.05） and COD Cr （r = 0.397, p 〈 0.05）while the testate amoebaewas significantly positively related to nitrification （r = 0.523, p 〈 0.01）. At the same time, some other associationswere also identified： the abundances of the large flagellates （r = 0.447, p 〈 0.01）, the metazoa （r = 0.718, p 〈 0.01） and species Aspidisca sulcata （r = 0.337, p 〈 0.05）were positively related to nitrification; the abundance of Aspidisca costatawas correlated to the TN （total nitrogen） removal （r = -0.374, p 〈 0.05 ）; the abundances of the sessile species Carchesium polypinum （r = 0.458, p 〈 0.01） and E. plicatilis （r = 0.377, p 〈 0.05）were correlatedwith the removal of suspended solids.

关键词： protozoan metazoan activated sludge treatment performance bioindicator

Local Stability to the Einstein-Euler System in Schwarzschild Space-time

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Acta Mathematicae Applicatae Sinica 2022年第2期38卷 352-367页

作者： Jun WU bo-ling guo Institute of Applied Physics and Computational Mathematics Beijing 100088China

We study the Schwarzschild spacetime solutions to the Einstein-Euler *** our analysis,we aim to show local stability under small *** resolve this problem,we use the Nash-Moser(-Hamilton)*** work was originally develop... 详细信息

关键词： schwarzschild metric local stability Nash-Moser(-Hamilton)theorem

Effect of oxygen content and heat treatment on carbide precipitation behavior in PM Ni-base superalloys

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International Journal of minerals,Metallurgy and Materials 2012年第9期19卷 827-835页

作者： Heng-san Liu Lin Zhang Xin-bo He Xuan-hui Qu Hong-min Zhu guo-qing Zhang State Key Laboratory for Advanced Metals and Materials Beijing Key Laboratory for Powder Metallurgy and Particulate Materials University of Science and Tech-nology Beijing Beijing 100083 China School of Metallurgical and Ecological Engineering University of Science and Technology Beijing Beijing 100083 China National Key Lab of High Temperature Structural Materials Beijing Institute of Aeronautical Materials Beijing 100095 China

The influence of oxygen content and heat treatment on the evolution of carbides in a powder metallurgy （PM） Ni-base superalloy was characterized. The results reveal that oxygen content has little influence on the precipitation of carbides inside the particles. However, under the consolidated state, stable Ti oxides on the particle surface act as nuclei for the precipitation of prior particle boundaries （PPB）. Also, oxygen can diffuse internally along grain boundaries under compressive stress, which favors the precipitation of carbides inside the particles. Therefore, a higher amount of carbides will appear with more oxygen content in the case of consolidated alloys. It is also observed that PPB can be disrupted into discontinuous particles at 1200℃, but this carbide network is hard to be eliminated completely. The combined MC-M23C6 morphology approves the nucleation and growth mechanism of carbide evolution.

关键词： powder metallurgy nickel alloys superalloys oxygen heat treatment carbides precipitation

Study on Force Mechanism for Therapeutic Effect of Pushing Manipulation with One-Finger Meditation Base on Similarity Analysis of Force and Waveform

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Chinese Journal of Integrative Medicine 2018年第7期24卷 531-536页

作者： FANG Lei FANG min guo min-min School of Rehabilitation Science Shanghai University of Traditional Chinese Medicine Department of Tuina Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Department of Mechanics and Engineer Science Fudan University

Objective： To reveal the force mechanism for therapeutic effect of pushing manipulation with one-finger meditation. Methods： A total of 15 participants were recruited in this study and assigned to an expert group, a skilled group and a novice group, with 5 participants in each group. Mechanical signals were collected from a biomechanical testing platform, and these data were further observed via similarity analysis and cluster analysis. Results： Comparing the force waveforms of manipulation revealed that the manipulation forces were similar between the expert group and the skilled group（P〉0.05）. The mean value of vertical force was 9.8 N, and 95% CI rang from 6.37 to 14.70 N, but there were significant differences compared with the novice group（P〈0.05）. The result of overall similarity coefficient cluster analysis showed that two kinds of manipulation forces curves were existed between the expert group and the skilled group. Conclusion： Pushing manipulation with one-finger meditation is a kind of light stimulation manipulation on the acupoint, and force characteristics of double waveforms continuously alternated during manual operation.

关键词： pushing manipulation with one-finger meditation Tuina biomechanics force characteristics waveform

Experimental study on dynamic response characteristics of isolated-span transmission lines after ice-shedding

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High Voltage 2023年第1期8卷 196-208页

作者： Guizao Huang bo Yan Yujun guo bo Zhang Guangning Wu School of Electrical Engineering Southwest Jiaotong UniversityChengduChina College of Aerospace Engineering Chongqing UniversityChongqingChina State Grid Henan Electric Power Research Institute ZhengzhouChina

The dynamic response characteristics,including maximum jump height and unbalanced tension,of isolated-span transmission lines after ice-shedding are investigated by means of experiments.A reduced-scale modelling method for ice-shedding from conductor lines is presented and verified with numerical simulations and full-scale test results in the literature.A parameter study on dynamic responses of isolated-span conductors under three ice-shedding scenarios,including whole span ice-shedding,partial ice-shedding and unzipping ice-shedding,is carried out by means of reduced-scale modelling *** effects of these parameters on the maximum jump height at typical positions and unbalanced tension in the tension tower are *** is observed that the partial iceshedding scenario may be the worst situation for electrical insulation clearance rather than the whole span ice-shedding ***,the position of maximum jump height along the span of isolated-span transmission lines after ice-shedding could be at around 2/5 of span length,which is different from the conventional opinion that the position is at the *** results may provide a foundation for the defining of the insulation clearance for an isolated-span transmission line and the structure design of tension tower arms in an iced zone.

关键词： dynamic characteristics insulation