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Perioperative blood transfusion is associated with post-operative infectious complications in patients with Crohn’s disease

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Gastroenterology Report 2018年第2期6卷 114-121,I0002页

作者： Nan lan Luca Stocchi Yi li bo Shen Center for Inflammatory bowel Disease and Digestive Disease and Surgery InstituteThe Cleveland Clinic FoundationClevelandOHUSA Department of Colorectal Surgery Digestive Disease and Surgery InstituteThe Cleveland Clinic FoundationClevelandOHUSA

Background:We have previously demonstrated that blood transfusion(BT)was associated with post-operative complications in patients undergoing surgery for Crohn’s disease(CD),based on our institutional data *** aim of this study was to verify the association between perioperative BT and infectious complications in CD patients enrolled in the American College of Surgeons National Surgical Quality Improvement Program(ACS NSQIP)***:All CD patients undergoing surgery between 2005 and 2013 were identified from *** were defined according to the ACS NSQIP *** primary outcome was infectious complications,including superficial,deep and organ/space surgical site infection,wound dehiscence,urinary tract infection,pneumonia,systemic sepsis and septic *** analyses were performed to assess the risk factors for post-operative ***:All 10100 eligible patients were included and 611(6.0%)received perioperative *** patients were older,lighter in weight and more likely to be functionally *** patients were more likely to have post-operative infectious complications than those without BT,including superficial surgical site infection(SSI)(10.8%vs 7.4%,p¼0.002),deep SSI(3.3%vs 1.6%,p¼0.003),organ/space SSI(14.2%vs 5.4%,plications(odds ratio[OR]¼2.2;95%confidence interval[CI]:1.8–2.7;p<0.001)and the risk increased with each administered unit of red blood cell(OR¼1.3,95%CI:1.2–1.5).Other independent factors were history of smoking,chronic heart disease,diabetes,hypertension and the use of ***-operative BT,however,was not found to be a risk factor to post-operative ***:Intra-and/or post-operative,not p

关键词： blood transfusion Crohn’s disease infectious complications surgical outcomes

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A systematic review of machine learning modeling processes and applications in ROP prediction in the past decade

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Petroleum Science 2024年第5期21卷 3496-3516页

作者： Qian li Jun-Ping li lan-lan Xie College of Environment and Civil Engineering Chengdu University of TechnologyChengdu610059SichuanChina State Key Laboratory of Geohazard Prevention and Geoenvironment Protection(Chengdu University of Technology) Chengdu610059SichuanChina Institute of Exploration Technology CAGSChengdu610059SichuanChina

Fossil fuels are undoubtedly important, and drilling technology plays an important role in realizing fossil fuel exploration;therefore, the prediction and evaluation of drilling efficiency is a key research goal in the industry. limited by the unknown geological environment and complex operating procedures, the prediction and evaluation of drilling efficiency were very difficult before the introduction of machine learning algorithms. This review statistically analyses rate of penetration(ROP) prediction models established based on machine learning algorithms;establishes an overall framework including data collection, data preprocessing, model establishment, and accuracy evaluation;and compares the effectiveness of different algorithms in each link of the process. This review also compares the prediction accuracy of different machine learning models and traditional models commonly used in this field and demonstrates that machine learning models are the most effective technical means in current ROP prediction modeling.

关键词： Drilling Rate of penetration(ROP)prediction Machine learning Accuracy evaluation

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Electrons dynamics control by shaping femtosecond laser pulses in micro/nanofabrication: modeling, method, measurement and application

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light(Science & Applications) 2017年第1期6卷 249-275页

作者： lan Jiang An-Dong Wang bo li Tian-Hong Cui Yong-Feng Lu Laser Micro/Nano-Fabrication Laboratory School of Mechanical EngineeringBeijing Institute of TechnologyBeijing 100081China Department of Mechanical Engineering University of MinnesotaMinneapolisMN 55455USA Department of Electrical Engineering University of Nebraska-LincolnLincolnNE 68588-0511USA

During femtosecond laser fabrication,photons are mainly absorbed by electrons,and the subsequent energy transfer from electrons to ions is of picosecond ***,lattice motion is negligible within the femtosecond pulse duration,whereas femtosecond photon-electron interactions dominate the entire fabrication ***,femtosecond laser fabrication must be improved by controlling localized transient electron dynamics,which poses a challenge for measuring and controlling at the electron level during fabrication ***-probe spectroscopy presents a viable solution,which can be used to observe electron dynamics during a chemical *** fact,femtosecond pulse durations are shorter than many physical/chemical characteristic times,which permits manipulating,adjusting,or interfering with electron ***,we proposed to control localized transient electron dynamics by temporally or spatially shaping femtosecond pulses,and further to modify localized transient materials properties,and then to adjust material phase change,and eventually to implement a novel fabrication *** review covers our progresses over the past decade regarding electrons dynamics control(EDC)by shaping femtosecond laser pulses in micro/nanomanufacturing:(1)Theoretical models were developed to prove EDC feasibility and reveal its mechanisms;(2)on the basis of the theoretical predictions,many experiments are conducted to validate our EDC-based femtosecond laser fabrication *** examples are reported,which proves that the proposed method can significantly improve fabrication precision,quality,throughput and repeatability and effectively control micro/nanoscale structures;(3)a multiscale measurement system was proposed and developed to study the fundamentals of EDC from the femtosecond scale to the nanosecond scale and to the millisecond scale;and(4)As an example of practical applications,our method was employed to fabricate some key structures in one of the 16 Ch

关键词： electrons dynamics control femtosecond laser micro/nano fabrication pulse shaping

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A cross-layer approach to enable multipacket transmission in MIMO-SDMA based Wlan

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2009年第2期10卷 271-278页

作者： Sheng-bo CHEN Wei CHEN Wei-lan HUANG li-jun ZHAI Xu-ming liU Department of Electronic Engineering. Tsinghua University Beijing 100084 China Nokia Research Center Beijing 100176 China

We propose a medium access control(MAC) protocol for uplink transmissions in wireless local area networks(Wlans),where both stations and access points(APs) are equipped with multiple antennas. The protocol solves some common problems in utilizing multiple input multiple output(MIMO) under the 802.11 protocol,e.g.,how to deploy preamble(training sequence) used for channel estimation and how to enable simultaneous data transmissions,and facilitates two simultaneous uplink data transmissions via a cross-layer approach. Furthermore,we develop a 3D discrete-time Markov model to analyze the per-formance of the proposed Wlan scheme. The analytical results are verified by simulation,and numerical results show that the system throughput can be significantly improved by our proposed scheme as compared with conventional schemes.

关键词： Multiple input multiple output (MIMO) Medium access control (MAC) Cross-layer design

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Projecting the potential distribution and analyzing the bioclimatic factors of four Rhododendron *** species under climate warming

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Journal of Forestry Research 2023年第6期34卷 1707-1721页

作者： lan Yang Huie li College of Agriculture Guizhou UniversityGuiyang 550025People’s Republic of China

Tsutsusi is one of the eight subgenera of the Rhododendron *** Tsutsusi species,***,***,***,and ***,have high ornamental and medicinal values,resulting in an increasing market *** species thrive in cool and humid environments and are widely distributed in Europe and *** global climate warming will affect the distribution of these valuable resources remains ***,this study analyzed the climatic suitability of these species for the first time on the basis of 1552 geographical distribution points and 19 bioclimatic factors using the maximum entropy *** results show that a suitable distribution area for all four species would decrease under climate *** main bioclimatic factors affecting their distribution are the mean temperature of the coldest quarter for ***,the mean diurnal range for ***,and precipitation of the warmest quarter for *** and *** addition,the contribution of the temperature-related bioclimatic factors to the distribution of *** and *** is higher than that of the associated precipitation-related climatic factors;in contrast,the contribution of precipitation-related bioclimatic factors to the distribution of *** and *** is higher than that of the temperature-related climatic *** results provide references for the introduction,conservation,sustainable development,and utilization of these four species in the future,and may also provide information with regards to other Rhododendron species.

关键词： Rhododendron simisii Rhododendron indicum Rhododendron schlippenbachii Rhododendron oldhamii Climate change Future distribution

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Surface-functionalized cellulose nanocrystals(CNC)and synergisms with surfactant for enhanced oil recovery in low-permeability reservoirs

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Petroleum Science 2023年第3期20卷 1572-1583页

作者： Zhe li Wan-li Kang Meng-lan li Hong-Bin Yang Tong-Yu Zhu Ying-Qi He Hai-Zhuang jang bo-bo Zhou Ji-Ting Hao Key Laboratory of Unconventional Oil&Gas Development China University of Petroleum(East China)Ministry of EducationQingdao266580ShandongPR China School of Petroleum Engineering China University of Petroleum(East China)Qingdao266580ShandongPR China

Nanocellulose,a natural polymeric nanomaterial,has attracted significant attention in enhanced oil recovery(EOR)applications due to its abundance,nanoscale,high oil-water interfacial adsorption *** this study,surface-functionalized cellulose nanocrystals(SF-CNCs)were prepared via hy-drochloric acid hydrolysis and chemical modification,with adaptable nanosize and considerable dispersion stability in low-permeability *** SF-CNCs were structurally characterized by FT-IR,Cryo-TEM,which have a diameter of 5-10 nm and a length of 100-200 *** SF-CNC dispersions possessed higher stability and stronger salt-tolerance than those of corresponding CNC dispersions,due to the strong hydrophilicity of the sulfonic acid *** was synergistically used with a non-ionic surfactant(APG1214)to formulate a combined flooding system(0.1 wt%SF-CNC+0.2 wt%APG1214).The combined flooding system exhibits strong emulsification stability,low oil-water interfacial tension of o.03 mN/m,and the ability to alter the wettability for oil-wetting ***,the combined system was_able to provide an optimum EOR efficiency of 20.2%in low-permeability cores with 30.13×10^(-3)μm^(2).*** can enlarge the sweep volume and increase the displacement efficiency ***,the newly formulated nanocellulose/surfactant combined system exhibits a remarkable EoR performance in low-permeability reservoirs.

关键词： Low-permeability reservoirs Enhanced oil recovery Cellulose nanocrystals(CNC) Surfactant Dispersion stability

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Selective recognition of HIV RNA by dinuclear metallic ligands

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Chinese Chemical Letters 2018年第11期29卷 1637-1640页

作者： Xuedong li bo Chen ling lan Ruili Wang Duqiang LUO li liu liang Cheng Beijing National Laboratory for Molecular Sciences (BNLMS) CAS Key Laboratory of Molecular Recognition and Function CAS Research/Education Center for Excellence in Molecular Sciences Institute of Chemistry Chinese Academy of Sciences Beijing 100190 China College of life Science Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of the Ministry of Education Hebei University Baoding 071002 China University of Chinese Academy of Sciences Beijing 100049 China

We describe the development of dinuclear metallic ligands to target specific HIV RNA structures. Two series of dipyridinyl-N bridged dinuclear metal complexes were synthesized in moderate to good yields and their binding activities toward TAR and RRE RNA were studied both experimentally and theoretically. The docking calculation elucidated some structure features in dimetallic complexes that can affect TAR RNA-binding properties.

关键词： HIV RNA Dinuclear metallic ligands Binding Molecular recognition Selectivity

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巴西龟代谢性骨病CT诊断病例报告

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动物医学进展 2025年第1期46卷 141-144页

作者：孙嘉徐甘靖宇江蓝刘波俞峰中国农业大学北京100193

代谢性骨病(MBD)是一种因钙缺乏或维生素D 3摄入不足引起的骨骼代谢障碍疾病,其临床表现为骨折、脊椎异常、难产、脱垂等症状。计算机断层扫描(CT)在兽医临床中应用的逐渐增加为龟、鳖类MBD提供了新的诊断方式。该病例中红耳巴西龟血检... 详细信息

代谢性骨病(MBD)是一种因钙缺乏或维生素D 3摄入不足引起的骨骼代谢障碍疾病,其临床表现为骨折、脊椎异常、难产、脱垂等症状。计算机断层扫描(CT)在兽医临床中应用的逐渐增加为龟、鳖类MBD提供了新的诊断方式。该病例中红耳巴西龟血检结果提示其肾脏、肝脏功能损害,钙磷代谢异常。CT扫查提示患龟全身组织大面积矿化、背甲凹陷,定量测量患龟背椎骨、神经骨和胸膜骨3处的骨骼密度远低于正常龟,诊断患龟有严重的MBD。治疗方案为对症治疗、改善饲养管理条件,同时对该龟补充维生素D 3。该病例报告系统陈述了龟鳖MBD的诊疗流程,同时表明了CT扫查可为龟鳖MBD精确诊断、治疗和预后提供新的参考。

关键词：龟代谢性骨病计算机断层扫描骨密度

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Recentprogress in thebiomedical application of PEDOT:PSS hydrogels

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Chinese Chemical Letters 2024年第10期35卷 13-27页

作者： Binhan Zhao Zheng li lan Zheng Zhichao Ye Yuyang Yuan Shanshan Zhang bo liang Tianyu li National Engineering Research Center of Innovation and Application of Minimally Invasive Instruments Sir Run Run Shaw HospitalSchool of MedicineZhejiangUniversityHangzhou 310028China Department of Translational Medicine Clinical Research Sir Run Run Shaw HospitalSchool of MedicineZhejiang UniversityHangzhou 310028China Biosensor National Special Laboratory College of Biomedical Engineering and Instrument ScienceZhejiang UniversityHangzhou 310028China School of Medicine Zhejiang UniversityHangzhou 310028China

Bioelectronics have gained substantial research attention owing to their potential applications in health monitoring and diagnose,and greatly promoted the development of ***,poly(3,4-ethylenedioxythiophene):polystyrene sulfonate(PEDOT:PSS)hydrogels have arose as a promising candi-date for the next-generation bioelectronic interface due to its high-conductivity,versatility,flexibility and *** this review,we highlight the recent advances of PEDOT:PSS hydrogels,including the gelation methods and modification strategies,and summarize their wide applications in different type of sensors and tissue engineering in *** expect that this work will provide valuable information regarding the functionalizations and applications of PEDOT:PSS hydrogels.

关键词： Conductingpolymer PEDOT:PSS hydrogels Conjugatedpolymer Gelation methods Biomedicalapplication

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Stem cell therapy:light in the tunnel for penetrating Crohn’s disease

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Gastroenterology Report 2023年第1期11卷 78-87页

作者： Nan lan Xianrui Wu bo Shen Center for Inflammatory bowel Disease Columbia University Irving Medical Center/NewYork Presbyterian HospitalNew YorkNYUSA Department of Colorectal Surgery The 6th Hospital of Sun Yat-Sen UniversityGuangzhouGuangdongP.R.China

Patients with Crohn’s disease frequently suffer from fistula resulting from adverse sequelae of persistent complicated active disease or surgical *** affects a patient’s quality of life and is directly associated with the need for surgical *** of fistula can be made through CT enterography,MR enterography,gastrograffin-based imaging,and transanal *** for fistula mainly consists of medication,endoscopic procedures,and *** are emerging approaches under current investigation,such as stem cell *** results showed a decent response in patients with perianal and rectovaginal fistula with minimal side *** investigation is still needed for other internal fistula.

关键词： Crohn’s disease fistula perianal disease stem cells therapy

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