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The mecha.isms of thermal solidification agent promoting steam diversion in heavy oil reservoirs

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Petroleum Science 2024年第3期21卷 1902-1914页

作者： Zha.-Xi Pang Qian-Hui Wang Qiang Meng bo Wang Dong liu State Key Laboratory of Petroleum Resources and Engineering China University of Petroleum(Beijing)Beijing102249China Liaohe Oilfield Institute CNPC ChinaPanjin124000LiaoningChina Henan Oilfield Institute Sinopec ChinaNanyang473400HenanChina Tianjin Branch of China National Offshore Oil Company(CNOOC)Ltd. Tianjin300452China

At high cycles of steam huff&puff,oil distribution in reservoirs becomes stronger heterogeneity due to steam *** solidification agent can be used to solve this *** solution is a lowviscosity liquid at normal temperature,but it can be solidified above 80℃.The plugging degree is up to 99%at 250℃.The sweep efficiency reaches 59.2%,which is 7.3%higher tha. pure steam *** addition,simultaneous injection of viscosity reducer and/or nitrogen foams can further enha.ce oil *** mecha.ism of this technology depends on its strong plugging ability,which cha.ges the flowing pattern of steam to effectively mobilize remaining *** reducer and nitrogen foams further expand the sweep range and extends the effective ***,thermal solidification agent can plug steam cha.neling paths and adjust steam flowing direction to significantly enha.ce oil recovery at high cycles of steam huff&puff.

关键词： Heavy oil reservoir Steam huff&puff Steam cha.neling Steam diversion Plugging performance Mecha.ism analysis

Investigation of hydroxyl-terminated polybutadiene propellant breaking cha.acteristics and mecha.ism impacted by submerged cavitation water jet

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Defence Technology（防务技术） 2024年第3期33卷 559-572页

作者： Wenjun Zhou Meng Zha. bo liu Youzhi Ma Youzhi Zha.g Xuanjun Wang Zhijian Laboratory Rocket Force University of EngineeringXi’an710025China

A submerged cavitation water jet(SCWJ)is an effective method to recycle solid propellant from obsolete solid engines by the breaking *** propellant's breaking modes and mecha.ical process under SCWJ impact are *** study aims to understand those impact breaking *** hydroxyl-terminated polybutadiene(HTPB)propellant was chosen as the research material,and a self-designed test system was used to conduct impact tests at four different working *** high-speed camera cha.acterized crack propagation,and the DIC method calculated strain cha.ge during the impact ***,micro and macro fracture morphologies were cha.acterized by scanning electron microscope(SEM)and computed tomography(CT)*** results reveal tha. the compressive strain concentration region locates right below the nozzle,and the shear strain region distributes symmetrically with the jet axis,which increases to 4% at first 16th ms,the compressive strain rises to 2% and 6% in the axial and transverse direction,*** two tensile cracks formed first at the compression strain concentrate region,and there generate many shear cracks around the tensile cracks,and those shear cracks tha. develop and aggregate cause the cracks to become wider and cut through the tensile cracks,forming the tensile-shear cracks and the impact parts eventually *** HTPB propellant forms a breaking hole sha.ed conical after impact 10 *** mass loss increases by 17 times at maximum,with the working pressure increasing by three ***,the damage value of the breaking hole remaining on the surface increases by 7.8 times while 2.9 times in the depth of the breaking *** breaking efficiency is closely affected by working *** failure modes of HTPB impacted by SCWJ are classified as tensile crack-dominated and tensile-shear crack-dominated damage mecha.isms.

关键词： Submerged cavitation water jet Hydroxyl-terminated polybutadiene propellant Breaking cha.acteristics Failure modes

Microplastics in sediment of the Three Gorges Reservoir:abundance and cha.acteristics under different environmental conditions

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Journal of Oceanology and Limnology 2024年第1期42卷 101-112页

作者： Wang LI bo ZU Yiwei liu Juncheng GUO Jiawen LI College of River and Ocean Engineering Chongqing Jiaotong UniversityChongqing 400074China Chongqing Research Academy of Ecology and Environmental Sciences Chongqing 401147China

Freshwater microplastic pollution is an urgent issue of global concern,and research on the distribution in reservoirs is *** investigated the microplastic pollution levels in wet sediments collected from the Three Gorges Reservoir,the largest reservoir of *** show tha. microplastics were ubiquitous in the sediments of the Three Gorges Reservoir,and their abundance ranged from 59 to 276 pp/kg(plastic particles per kg,dry weight).Economic development and total population were important factors affecting the spatial heterogeneity of microplastic abundance,and the contribution of large cities along the reservoir to microplastic pollution should be paid with more *** microplastics were the most abundant type of microplastic particles in reservoir sediments,whereas polystyrene,polypropylene,and polyamide were the main types of *** apparent spatial heterogeneity in morphology and color of microplastics is attributed to different anthropogenic or landbased pollution ***,the accumulation of microplastics near the inlet of tributaries reflects the role of potential contributors of *** importantly,multiple bisphenols(BPs)and heavy metals detected at the microplastic surfaces indicate tha. microplastics can act as carriers of these pollutants in the environment in the same way as sediments did,which may alter the environmental fate and toxicity of these ***,we conclude tha. the Three Gorges Reservoir ha. been contaminated with microplastics,which posed a stress risk for organisms who ingest them along with their associated pollutants(BPs,heavy metals).

关键词： microplastics Three Gorges Reservoir sediment bisphenol heavy metal

Type Synthesis of Self-Alignment Parallel Ankle Reha.ilitation Robot with Suitable Passive Degrees of Freedom

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Chinese Journal of Mecha.ical Engineering 2024年第1期37卷 160-175页

作者： Ya liu Wenjuan Lu Dabao Fan Weijian Tan bo Hu Daxing Zeng School of Mecha.ical Engineering Yanshan UniversityQinhuangdao 066004China School of Mecha.ical Engineering Dongguan University of TechnologyDongguan 523808China Dongguan Engineering Technology Research Center for Parallel Robot Dongguan 523808China The DGUT Innovation Center of Robotics and Intelligent Equipment Dongguan 523808China

The current parallel ankle reha.ilitation robot(ARR)suffers from the problem of difficult real-time alignment of the human-robot joint center of rotation,which may lead to secondary injuries to the *** study investigates type synthesis of a parallel self-alignment ankle reha.ilitation robot(PSAARR)based on the kinematic cha.acteristics of ankle joint rotation center drift from the perspective of introducing"suitable passive degrees of freedom(DOF)"with a suitable number and ***,the self-alignment principle of parallel ARR was proposed by deriving conditions for transforming a human-robot closed cha.n(HRCC)formed by an ARR and human body into a kinematic suitable constrained system and introducing conditions of"decoupled"and"less limb".Second,the relationship between the self-alignment principle and actuation wrenches(twists)of PSAARR was analyzed with the velocity Jacobian matrix as a"bridge".Subsequently,the type synthesis conditions of PSAARR were ***,a PSAARR synthesis method was proposed based on the screw theory and type of PSAARR synthesis ***,an HRCC kinematic model was established to verify the self-alignment capability of the *** this study,93 types of PSAARR limb structures were synthesized and the self-alignment capability of a human-robot joint axis was verified through kinematic analysis,which provides a theoretical basis for the design of such an ARR.

关键词： Ankle reha.ilitation robot Self-alignment Parallel mecha.ism Type synthesis Screw theory

On the electric beha.iour of conductive grease inside the contact zone

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Friction 2024年第4期12卷 683-697页

作者： Yuxin ZHOU Jinjie liu Xinming LI He CHONG bo ha. Qinghua BAI SKF(Sha.gha.)Automotive Technologies Co. Ltd.Shanghai 201814China School of Mecha.ical and Automotive Engineering Qingdao University of TechnologyQingdao 266250China

Conductive grease ha. been considered as a potential solution in addressing electric erosion issue inside motor *** the conductive grease performance,especially the electric and tribological beha.iour is crucial for its *** paper combines bulk grease cha.acterization and contact film study considering both electrical and tribological loading *** results show tha. the electric performance for the selected conductive grease sample is electric field dependent,including both frequency and voltage *** film impedance inside the contact area is closely related to the external electric field,running condition,and lubrication *** following film impedance calculation tells tha. not only bulk grease electric parameters,but the contact parameter,lubricant film contour and lubrication condition should be considered when performing the overall bearing electrical modelling.

关键词： Electric erosion lubricant conductivity grease film impedance

Recent progresses of exosome-liposome fusions in drug delivery

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Chinese Chemical Letters 2024年第2期35卷 107-117页

作者： Lulu Zheng bo Hu Deyao Zha. Wenjing liu Qing liu Yuanyu Huang Sha.bo Ruan School of Life Science Advanced Research Institute of Multidisciplinary ScienceSchool of Medical TechnologyKey Laboratory of Molecular Medicine and BiotherapyKey Laboratory of Medical Molecule Science and Pharmaceutics EngineeringBeijing Institute of TechnologyBeijing 100081China Department of Radiation Oncology The First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450000China Beijing Key Laboratory of Drug Resistance Tuberculosis Research Beijing Tuberculosis and Thoracic Tumor Research Instituteand Beijing Chest HospitalCapital Medical UniversityBeijing 101149China

Exosomes are membrane-bound nanoscale extracellular vesicles,which produced by almost all *** to the excellent biocompatibility,long circulation time as well as low immunogenicity,exosomes as naturally-derived drug delivery carriers ha.e experienced explosive growth over the past ***,issues such as insufficient loading efficiency,heterogeneous delivery efficiency,uncontrollable targeting ability,and low production limit their wide ***,the emerging exosome-liposome fusion strategy ha. become a potential approach to solve such ***,this review mainly focuses on the currently developed exosome-liposome fusion strategy and their application in drug delivery as well as disease *** review aims to shed light on the advantages of fusion strategy in drug delivery and provides a better understanding for more rational *** current cha.lenge and future perspective regarding their clinical translation and application will also be discussed.

关键词： Exosome Liposome Membrane fusion Drug delivery Disease treatment

Mapping the intellectual structure and emerging trends for the application of nanomaterials in gastric cancer:A bibliometric study

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World Journal of Gastrointestinal Oncology 2024年第5期16卷 2181-2199页

作者： bo-Na liu Xiao-Li Gao Ying Piao Department of Oncology General Hospital of Northern Theater CommandShenyang 110015Liaoning ProvinceChina

BACKGROUND Recent reviews ha.e outlined the main nanomaterials used in relation to gastrointestinal tumors and described the basic properties of these ***,the research hotspots and trends in the application of nanomaterials in gastric cancer(GC)remain *** To demonstrate the knowledge structure and evolutionary trends of research into the application of nanomaterials in *** Publications related to the application of nanomaterials in GC were retrieved from the Web of Science Core Collection for this systematic review and bibliometric *** and CiteSpace were used for bibliometric and visualization *** From 2000 to 2022,the application of nanomaterials in GC developed *** keyword co-occurrence analysis showed tha. the related research topics were divided into three clusters:(1)The application of nanomaterials in GC treatment;(2)The application and toxicity of nanomaterials in GC diagnosis;and(3)The effects of nanomaterials on the biological beha.ior of GC ***,silver nanoparticles,and green synthesis are the latest high-frequency keywords tha. represent promising future research *** The application of nanomaterials in GC diagnosis and treatment and the mecha.isms of their effects on GC cells ha.e been major themes in this field over the past 23 years.

关键词： Nanomaterials Gastric cancer Bibliometrics Drug delivery VOSviewer CiteSpace Systematic review

Rapid Simultaneous Determination of Four Ganoderic Acids in Ganoderma(Chinese Name:Lingzhi)by Direct Infusion-Multiple Reaction Monitoring Cubed

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Journal of Analysis and Testing 2024年第1期8卷 52-62页

作者： Nian Wu bo Peng Ting Li Pengfei Tu Shengpeng Wang bo Li Wenjing liu Yuelin Song Modern Research Center for Traditional Chinese Medicine Beijing Research Institute of Chinese MedicineBeijing University of Chinese MedicineBeijing 100029China Amway(China)botanical Research Center Wuxi 214011China State Key Laboratory of Quality Research in Chinese Medicine Institute of Chinese Medical SciencesUniversity of MacaoTaipa 999078China Amway(Sha.gha.)Innovation&Science Co. LtdShanghai 201508China School of Pha.macy Henan University of Chinese MedicineZhengzhou 450046China

Attributing to the rapid demand expansion for the edible medicinal materials in the market,the limited throughput of highperformance liquid chromatography-multiple reaction monitoring(HPLC-MRM)cannot fully address the measurement workload for a huge number of testing ***,it is urgent to pursue more efficient approaches for the quality *** of the greater selectivity of MRM cubed(MRM^(3))over MRM,there might be a cha.ce to omit the time-intensive LC *** current study,we attempted to develop a direct infusion(DI)-MRM^(3) program,and the applicability was thereafter assessed through simultaneous determination of four ganoderic acids(GAs)in one of the most famous tonic herbal medicines namely Ganoderma(Chinese name:Lingzhi).Primary parameters such as Q1>Q3>QLIT ion transitions,collision energy(CE),and excitation energy were optimized by programming online energy-resolved mass spectrometry with authentic compounds.A single DI-MRM measurement merely costed four minutes,and in spite of the wide occurrences of isomers,satisfactory selectivity was *** validation assays demonstrated the method to be sensitive,precise,accurate,and *** quantitative results from DI-MRM^(3) were also justified by conducting LC-MRM measurements in *** differences occurred for the content patterns between the two original sources namely Ganoderma lucidum and ***,and,moreover,either cultivar or ha.vest time showed dramatical influence on the quantitative features of the four targeted *** importantly,DI-MRM3 is a meaningful analytical option for rapid quantitative analysis of herbal medicines,because of the comparable reliability,nonetheless,less consumptions of both measurement time and solvent,compared with LC-MRM.

关键词： Direct infusion Multiple reaction monitoring cubed High-throughput quantitative analysis Ganoderic acids Ganoderma

An Approximation Algorithm for the Parallel-Machine Customer Order Scheduling with Delivery Time and Submodular Rejection Penalties

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Journal of the Operations Research Society of China 2024年第2期12卷 495-504页

作者： Hong-Ye Zheng Suo-Gang Gao Wen liu bo Hou School of Mathematical Sciences Hebei Normal UniversityShijiazhuang 050024HebeiChina

In this paper,we consider the parallel-machine customer order scheduling with delivery time and submodular rejection *** this problem,we are given m dedicated machines in parallel and n customer *** order ha. a delivery time and consists of m product types and each product type should be manufactured on a dedicated *** order is either rejected,in which case a rejection penalty ha. to be paid,or accepted and manufactured on the m dedicated *** objective is to find a solution to minimize the sum of the maximum delivery completion time of the accepted orders and the penalty of the rejected orders which is determined by a submodular *** design an LP rounding algorithm with approximation ratio of n+1 for this problem.

关键词： Order scheduling Delivery time Submodular rejection penalty Approximation algorithm