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Building the toolbox for in vivo glia-to-neuron reprogramming

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Neural Regeneration Research 2024年第6期19卷 1171-1172页

作者： Ye Xie bo chen Departments of Ophthalmology and Neuroscience Icahn School of Medicine at Mount Sinai

Unlike regenerative-competent species that possess a remarkable intrinsic capacity to replenish lost neurons and restore neurocircuits spontaneously, the central nervous system in adult mammals lacks the ability to compensate for the neuronal loss caused by neurodegenerative diseases or traumatic injuries resulting in permanent loss of functionality. Inspired by earlier discoveries that radial glia or astrocytes isolated from the postnatal cortex can generate neurons,

关键词： CONVERSION DISEASE

Intersection theory rules symbology

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Science China(Physics,Mechanics & Astronomy) 2024年第2期67卷 93-104页

作者： Jiaqi chen bo Feng Lilin Yang Beijing Computational Science Research Center Beijing 100084China Zhejiang Institute of Modern Physics School of PhysicsZhejiang UniversityHangzhou 310027China Peng Huanwu Center for Fundamental Theory Hefei 230026China

We propose a novel method to determine the structure of symbols for any family of polylogarithmic Feynman *** the d log-bases and simple formulas for the leading order and next-to-leading contributions to the intersection numbers,we give a streamlined procedure to compute the entries in the coefficient matrices of canonical differential equations,including the symbol letters and the rational *** also provide a selection rule to decide whether a given matrix element must be *** symbol letters are deeply related to the poles of the integrands and also have interesting connections to the geometry of Newton *** method can be applied to many cutting-edge multi-loop *** simplicity of our results also hints at the possible underlying structure in perturbative quantum field theories.

关键词： scattering amplitude Feynman integral symbology

Finite-time tracking control of heterogeneous multi-AUV systems with partial measurements and intermittent communication

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Science China(Information Sciences) 2024年第5期67卷 165-182页

作者： bo chen Jiangping HU Bijoy Kumar GHOSH School of Automation Engineering University of Electronic Science and Technology of China Key Laboratory of Intelligent Analysis and Decision on Complex Systems Chongqing University of Posts and Telecommunications Yangtze Delta Region Institute (Huzhou) University of Electronic Science and Technology of China Department of Mathematics and Statistics Texas Tech University

The development of a distributed trajectory-tracking control strategy that is independent of velocity measurements is critical to achieving finite-time tracking control of autonomous underwater vehicle(AUV) systems. In this study, a group of heterogeneous AUV systems with intermittent communication links is considered and a finite-time trajectory-tracking control strategy is developed. The strategy includes two observers and one controller proposed for each follower-AUV. The first observer, a hybrid finite-time observer,estimates the state of the leader, whereas the second observer, which relies only on the position measurement,is proposed to estimate the states of the follower-AUV itself. In addition, a distributed trajectory-tracking controller is designed using the states estimated by the intermittent communication network even without velocity measurements. A homogeneous technique is utilized to prove that all followers can track the leader in a finite time. Finally, the effectiveness of the developed finite-time tracking control strategy is illustrated by numerical simulations.

关键词： distributed observer finite-time tracking homogeneous technique intermittent communication multiple heterogeneous AUVs

A Random Fusion of Mix 3D and Polar Mix to Improve Semantic Segmentation Performance in 3D Lidar Point Cloud

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Computer Modeling in Engineering & Sciences 2024年第7期140卷 845-862页

作者： bo Liu Li Feng Yufeng chen School of Computer Science and Engineering Macao University of Science and TechnologyMacao999078China School of Computer Science and Artificial Intelligence Chaohu UniversityChaohu238000China Institute of Vehicle Information Control and Network Technology Hubei University of Automotive TechnologyShiyan442002China

This paper focuses on the effective utilization of data augmentation techniques for 3Dlidar point clouds to enhance the performance of neural network *** point clouds,which represent spatial information through a collection of 3D coordinates,have found wide-ranging *** augmentation has emerged as a potent solution to the challenges posed by limited labeled data and the need to enhance model generalization *** of the existing research is devoted to crafting novel data augmentation methods specifically for 3D lidar point ***,there has been a lack of focus on making the most of the numerous existing augmentation *** this deficiency,this research investigates the possibility of combining two fundamental data augmentation *** paper introduces PolarMix andMix3D,two commonly employed augmentation techniques,and presents a new approach,named *** of using a fixed or predetermined combination of augmentation methods,RandomFusion randomly chooses one method from a pool of options for each instance or *** innovative data augmentation technique randomly augments each point in the point cloud with either PolarMix or *** crux of this strategy is the random choice between PolarMix and Mix3Dfor the augmentation of each point within the point cloud data *** results of the experiments conducted validate the efficacy of the RandomFusion strategy in enhancing the performance of neural network models for 3D lidar point cloud semantic segmentation *** is achieved without compromising computational *** examining the potential of merging different augmentation techniques,the research contributes significantly to a more comprehensive understanding of how to utilize existing augmentation methods for 3D lidar point *** data augmentation technique offers a simple yet effective method to leverage the diversity of augmentation techniques and boost the ro

关键词： 3D lidar point cloud data augmentation RandomFusion semantic segmentation

Cluster-Based Massive Access for Massive MIMO Systems

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China Communications 2024年第1期21卷 24-33页

作者： Shiyu Liang Wei chen Zhongwen Sun Ao chen bo Ai State Key Laboratory of Advanced Rail Autonomous Operation Beijing Jiaotong UniversityBeijing 100091China School of Electronic and Information Engineering Beijing Jiaotong UniversityBeijing 100091China Frontiers Science Center for Smart High-speed Railway System Beijing Jiaotong UniversityBeijing 100091China Key Laboratory of Railway Industry of Broadband Mobile Information Communications Beijing Jiaotong UniversityBeijing 100091China Beijing Engineering Research Center of High-speed Railway Broadband Mobile Communications Beijing Jiaotong UniversityBeijing 100091China School of Information Engineering Zhengzhou UniversityZhengzhou 450001China

Massive machine type communication aims to support the connection of massive devices,which is still an important scenario in *** this paper,a novel cluster-based massive access method is proposed for massive multiple input multiple output *** exploiting the angular domain characteristics,devices are separated into multiple clusters with a learned cluster-specific dictionary,which enhances the identification of active *** detected active devices whose data recovery fails,power domain nonorthogonal multiple access with successive interference cancellation is employed to recover their data via *** results show that the proposed scheme and algorithm achieve improved performance on active user detection and data recovery.

关键词： compressive sensing dictionary learning multiuser detection random access

Building Semantic Communication System via Molecules:An End-to-End Training Approach

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China Communications 2024年第7期21卷 113-124页

作者： cheng Yukun chen Wei Ai bo School of Electronic and Information Engineering Beijing Jiaotong UniversityBeijing 100091China Frontiers Science Center for Smart High-speed Railway System Beijing Jiaotong UniversityBeijing 100091China Key Laboratory of Railway Industry of Broadband Mobile Information Communications Beijing Jiaotong UniversityBeijing 100091China Beijing Engineering Research Center of High-speed Railway Broadband Mobile Communications Beijing Jiaotong UniversityBeijing 100091China School of Information Engineering Zhengzhou UniversityZhengzhou 450001China

The concept of semantic communication provides a novel approach for applications in scenarios with limited communication *** this paper,we propose an end-to-end(E2E)semantic molecular communication system,aiming to enhance the efficiency of molecular communication systems by reducing the transmitted ***,following the joint source channel coding paradigm,the network is designed to encode the task-relevant information into the concentration of the information molecules,which is robust to the degradation of the molecular communication ***,we propose a channel network to enable the E2E learning over the non-differentiable molecular *** results demonstrate the superior performance of the semantic molecular communication system over the conventional methods in classification tasks.

关键词： deep learning end-to-end learning molecular communication semantic communication

Recovery of scandium from silicate minerals by high-pressure leaching in sulfuric acid

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Journal of Rare Earths 2024年第7期42卷 1375-1384,I0007页

作者： Peng Yan Xiaoming chen Likun Gao bo Yang Faculty of Metallurgical and Energy Engineering Kunming University of Science and TechnologyKunming650093China Faculty of Land Resources Engineering Kunming University of Science and TechnologyKunming650093China School of Chemistry and Chemical Engineering Kunming UniversityKunming650214China

This study investigated the leaching of scandium from a Sc-bearing silicate *** Sc concentrate obtained by beneficiation pre-enrichment has 1.03×10^(−4) wt%Sc and 14.66 wt%*** main Sc-bearing minerals are limonite,chlorite,sericite,and hornblende,in the form of ***-pressure leaching(HPL)with sulfuric acid(98 wt%)and NaF was used to dispose this *** Sc leaching efficiency of 91.82%was obtained under the optimum conditions,which are pressure of 5.0×10^(5) Pa,A/O value of 1.1,L/S value of 1.8,NaF dosage of 2 wt%,at 130℃ for 6 *** X-ray diffraction(XRD)and scanning electron microscopy(SEM)results show that the residue is mainly quartz phase in the multihole *** with ordinary leaching for silicate,high-pressure leaching has significant advantages in saving acid and energy consumption.

关键词： Silicate minerals Scandium High-pressure Leaching Concentrated sulfuric acid Rare earths

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Cooperative User-Scheduling and Resource Allocation Optimization for Intelligent Reflecting Surface Enhanced LEO Satellite Communication

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China Communications 2024年第2期21卷 227-244页

作者： Meng Meng bo Hu Shanzhi chen Jianyin Zhang State Key Lab of Networking and Switching Technology Beijing University of Posts and TelecommunicationsBeijing 100876China State Key Lab of Wireless Mobile Communication China Academy of Telecommunication TechnologyBeijing 100191China Research Institute of China Mobile Beijing 100053China

Lower Earth Orbit(LEO) satellite becomes an important part of complementing terrestrial communication due to its lower orbital altitude and smaller propagation delay than Geostationary satellite. However, the LEO satellite communication system cannot meet the requirements of users when the satellite-terrestrial link is blocked by obstacles. To solve this problem, we introduce Intelligent reflect surface(IRS) for improving the achievable rate of terrestrial users in LEO satellite communication. We investigated joint IRS scheduling, user scheduling, power and bandwidth allocation(JIRPB) optimization algorithm for improving LEO satellite system *** optimization problem of joint user scheduling and resource allocation is formulated as a non-convex optimization problem. To cope with this problem, the nonconvex optimization problem is divided into resource allocation optimization sub-problem and scheduling optimization sub-problem firstly. Second, we optimize the resource allocation sub-problem via alternating direction multiplier method(ADMM) and scheduling sub-problem via Lagrangian dual method ***, we prove that the proposed resource allocation algorithm based ADMM approaches sublinear convergence theoretically. Finally, we demonstrate that the proposed JIRPB optimization algorithm improves the LEO satellite communication system throughput.

关键词： convex optimization intelligent reflecting surface LEO satellite communication OFDM

Constructing the metabolic network of wheat kernels based on structure-guided chemical modification and multi-omics data

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Journal of Genetics and Genomics 2024年第7期51卷 714-722页

作者： Zhitao Tian Jingqi Jia bo Yin Wei chen National Key Laboratory of Crop Genetic Improvement and National Center of Plant Gene Research(Wuhan) Huazhong Agricultural UniversityWuhanHubei 430070China Hubei Hongshan Laboratory WuhanHubei 430070China

Metabolic network construction plays a pivotal role in unraveling the regulatory mechanism of biological activities,although it often proves to be challenging and labor-intensive,particularly with non-model *** this study,we develop a computational approach that employs reaction models based on the structure-guided chemical modification and related compounds to construct a metabolic network in *** construction results in a comprehensive structure-guided network,including 625 identified metabolites and additional 333 putative reactions compared with the Kyoto Encyclopedia of Genes and Genomes *** a combination of gene annotation,reaction classification,structure similarity,and correlations from transcriptome and metabolome analysis,a total of 229 potential genes related to these reactions are identified within this *** validate the network,the functionality of a hydroxycinnamoyltransferase(TraesCS3D01G314900)for the synthesis of polyphenols and a rhamnosyltransferase(TraesCS2D01G078700)for the modification of flavonoids are verified through in vitro enzymatic studies and wheat mutant tests,*** research thus supports the utility of structure-guided chemical modification as an effective tool in identifying causal candidate genes for constructing metabolic networks and further in metabolomic genetic studies.

关键词： Metabolic network Chemical modification Genetic study Wheat kernel Multi-omics