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Three New Species of Diploderma Hallowell, 1861 (Reptilia: Squamata: Agamidae) from the Shaluli Mountains in Western Sichuan, China

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Asian Herpetological Research 2022年第4期13卷 205-223页

作者： bo cai Meihua ZHANG Jing LI Simeng DU Feng XIE Mian HOU Huaming ZHOU Jianping JIANG CAS Key Laboratory of Mountain Ecological Restoration and Bioresource Utilization Ecological Restoration and Biodiversity Conservation Key Laboratory of Sichuan ProvinceChengdu Institute of BiologyChinese Academy of SciencesChengdu 610041SichuanChina Ganzi Institute of Forestry Research Kangding 626001SichuanChina College of Continuing(Online)Education Sichuan Normal UniversityChengdu 610068SichuanChina University of the Chinese Academy of Sciences Beijing 100049China Mangkang Biodiversity and Ecological Station Tibet Ecological Safety Monitor NetworkChangdu 854500TibetChina

In recent years,taxonomic research of the genus Diploderma has made great progress,but there are still areas lacking relevant *** 2020-2021,we carried out survey of reptile diversity in and around the Shaluli Mountains and collected some specimens of *** which,based on systematics inferred from mitochondrial ND2 gene sequence and morphological data,three new species were recognized:Diploderma daochengense *** the Shuiluo River and Muli River valleys in southeastern Daocheng County,*** *** the upper-middle valleys of the Yalong River in Xinlong County,and *** *** the Yalong River middle valley and Liqiu River ***,these three new species formed three monophyletic lineages with strongly supported and nested into the subclade I of the Bayesian and Maximum Likelihood *** uncorrected mean genetic distance between these new species and their closely related species was 4.3%(*** ***),3.4%(*** ***)and 5.5%(*** ***),higher than many pairs of species of *** respect to the morphology,*** *** be easily diagnosed from *** byhaving smoothupper edge of the dorsolateral stripes,cyan or dark olive green to yellow gular spots inbothsexes and light yelloworwhite ventrolateral body in males;*** *** be easily diagnosed from *** by having cyan gular spot in both sexes;*** *** be easily diagnosed from *** by having more T4S 20-25(average 23),more F4S 16-20(average 17)and yellow to light yellow ventrolateral body,yellow gular spot present in *** date,the number of species of the genus Diploderma has increased to 40,of which 37 species have been known in China.

关键词： Ganzi taxonomy Hengduan Mountains Mountain Dragons RGBcolormodel

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An Integrated PDMS Electrophoresis Microchip with LED Induced Fluorescence Detection

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稀有金属材料与工程 2006年第A3期35卷 315-318页

作者： Changchun Liu Dafu Cui Haoyuan cai bo Su Xing Chen Haining Wang Zhaoxin Geng State Key Laboratory of Transducer Technology Institute of Electronics Chinese Academy of Sciences Beijing 100080 China

A PDMS electrophoresis microchip,which integrated with optical fiber for fluorescence detection,was fabricated by using silicon master.A deep reactive ion etches (DRIE) technology was used to fabricate the silicon master with positive *** PDMS replica was fabricated by casting PDMS prepolymer against the silicon master,where an optical fiber was first fixed on the end of separation *** improve the rigid characteristics of integrated PDMS microchip,the chips were subsequently assembled by reversible sealing against glass plate.A blue light emitting diode (LED) was used as excitation light sources for inducing fluorescence detection through coupling LED light into the optical *** an application, integrated PDMS microchip was tested in the capillary electrophoresis separation of DNA *** results showed that DNA markers could be effectively separated and detected except for the segments of 271 and 281.

关键词： microfluidic chip optical fiber DNA separation LED detection

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含对苯二酚丙烯酰胺结构的聚氨酯涂层的制备及性能研究

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化学与粘合 2024年第1期46卷 20-24,34页

作者：王伟时晓慧蔡博张智嘉魏浩吕俊彦海军工程大学舰船与海洋学院湖北武汉430033 海军驻葫芦岛地区军事代表室辽宁葫芦岛125004 青岛哈尔滨工程大学创新发展中心山东青岛266000 青岛斯坦德标准检测有限公司山东青岛266000

海洋污损生物附着在水下设备表面会对海洋工业造成严重危害,如导致船舶航行阻力增大、能耗增加及船体腐蚀等。鉴于此,研制高效、环境友好的海洋防污材料具有重要的经济及战略意义。选择聚氨酯弹性体为基体树脂,将合成的具有防污功能的... 详细信息

海洋污损生物附着在水下设备表面会对海洋工业造成严重危害,如导致船舶航行阻力增大、能耗增加及船体腐蚀等。鉴于此,研制高效、环境友好的海洋防污材料具有重要的经济及战略意义。选择聚氨酯弹性体为基体树脂,将合成的具有防污功能的双羟基封端丙烯酰胺(OH-PHABA-OH)引入其中制备了一种非释放、表面自富集辣椒碱衍生物的聚氨酯防污涂层(PUP-x%)。对苯二酚丙烯酰胺(PHABA)含量为25%时(PUP-25%),树脂状态最佳,同时防污实验结果表明该涂层可以抑制90%以上的细菌和硅藻黏附,具有较好的长效静态防污能力。

关键词：对苯二酚聚氨酯抗菌抗藻防污

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本体聚合PMMA基复合介质膜的储能特性研究

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绝缘材料 2024年第4期57卷 22-27页

作者：蔡博赵月涛孟祥硕周榆久王礼坤叶虎潘齐凤徐建华江苏科技大学海洋学院江苏镇江212003 中国振华(集团)新云电子元器件有限责任公司贵州贵阳550018 电子科技大学光电科学与工程学院四川成都610054

目前有机薄膜电容器中的介质材料多为线性电介质,这类聚合物的介电常数通常较低,造成电容器储能密度普遍偏低,而新型高储能聚合物介质材料一般又存在介质损耗高的问题。聚甲基丙烯酸甲酯(PMMA)与高储能含氟聚合物的相容性较好,常被用来... 详细信息

目前有机薄膜电容器中的介质材料多为线性电介质,这类聚合物的介电常数通常较低,造成电容器储能密度普遍偏低,而新型高储能聚合物介质材料一般又存在介质损耗高的问题。聚甲基丙烯酸甲酯(PMMA)与高储能含氟聚合物的相容性较好,常被用来改善后者的力学和击穿性能,但市售的PMMA存在本征介质损耗过高的问题。为了降低PMMA的介质损耗,本文用甲基丙烯酸甲酯(MMA)与苯乙烯(St)合成MMA-St共聚物(MS),将不同比例的MS掺入本体聚合的PMMA中形成复合体系,并研究复合体系的介电特性、储能特性及绝缘特性。结果表明:该复合体系可以显著降低PMMA的介质损耗,相较于PMMA更适合作为高储能聚合物的改性材料。其中复合10%MS的介质膜在5 500 kV/cm电场下获得了5 J/cm^(3)的放电能量密度,充放电效率达到83%。

关键词：聚甲基丙烯酸甲酯介质损耗储能全有机复合介质膜

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VIBRATION CHARACTERISTICS OF FLUID-STRUCTURE INTERACTION OF CONICAL SPIRAL TUBE BUNDLE

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Journal of Hydrodynamics 2010年第1期22卷 121-128页

作者： YAN Ke GE Pei-qi BI Wen-bo SU Yan-cai HU Rui-rong Key Laboratory of High Efficiency and Clean Mechanical Manufacture Ministry of Education School of Mechanical Engineering Shandong University Jinan 250061 China

Heat transfer enhancement is achieved by flow-induced vibration in elastic tube bundles heat exchangers. For a further understanding of heat transfer enhancement mechanism and tube structure optimization, it is of importance to study the vibration characteristics of fluid-structure interaction of tube bundles. The finite element method is applied in the study of fluid-structure interaction of a new type elastic heat transfer element, i.e., the dimensional conical spiral tube bundle. The vibration equation and element matrix for the tube are set up by the regulation of different helical angles and coordinate transformation, together with the simplification of the joint body of the two pipes. The vibration characteristics of conical spiral tube bundle are analyzed at different velocities of the tube-side flow, and the critical velocity of vibration buckling is obtained. The results show that the natural frequency of the tube bundle decreases as the flow speed increases, especially for the first order frequency, and the critical velocity of vibration buckling is between 1.2665 m/s-1.2669 m/s. The vibration mode of conical spiral tube bundle is mainly z-axial, which is feasible to be induced and controlled.

关键词： conical spiral tube heat exchanger finite element method fluid-structure interaction vibration characteristics

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Weighted total variation using split Bregman fast quantitative susceptibility mapping reconstruction method

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Chinese Physics B 2018年第8期27卷 645-654页

作者： Lin Chen Zhi-Wei Zheng Li-Jun Bao Jin-Sheng Fang Tian-He Yang Shu-Hui cai Cong-bo cai Department of Electronic Science Fujian Provincial Key Laboratory of Plasma and Magnetic ResonanceXiamen UniversityXiamen 361005China Magnetic Resonance Center Zhongshan HospitalMedical College of Xiamen UniversityXiamen 361004China Department of Communication Engineering Xiamen UniversityXiamen 361005China

An ill-posed inverse problem in quantitative susceptibility mapping （QSM） is usually solved using a regularization and optimization solver, which is time consuming considering the three-dimensional volume data. However, in clinical diagnosis, it is necessary to reconstruct a susceptibility map efficiently with an appropriate method. Here, a modified QSM reconstruction method called weighted total variation using split Bregman （WTVSB） is proposed. It reconstructs the susceptibility map with fast computational speed and effective artifact suppression by incorporating noise-suppressed data weighting with split Bregman iteration. The noise-suppressed data weighting is determined using the Laplacian of the calculated local field, which can prevent the noise and errors in field maps from spreading into the susceptibility inversion. The split Bregman iteration accelerates the solution of the Ll-regularized reconstruction model by utilizing a preconditioned conjugate gradient solver. In an experiment, the proposed reconstruction method is compared with truncated k-space division （TKD）, morphology enabled dipole inversion （MEDI）, total variation using the split Bregman （TVSB） method for numerical simulation, phantom and in vivo human brain data evaluated by root mean square error and mean structure similarity. Experimental results demonstrate that our proposed method can achieve better balance between accuracy and efficiency of QSM reconstruction than conventional methods, and thus facilitating clinical applications of QSM.

关键词： quantitative susceptibility mapping ill-posed inverse problem noise-suppressed data weighting split Bregman iteration

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Novel matrine derivative MD-1 attenuates hepatic fibrosis by inhibiting EGFR activation of hepatic stellate cells

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Protein & Cell 2016年第9期7卷 662-672页

作者： Yi Feng Hai-yan Ying Ying Qu Xiao-bo cai Ming-yi Xu Lun-gen Lu Department of Gastroenterology Shanghai General Hospital Nanjing Medical University Shanghai 200080 China

Matrine （MT）, the effective component of Sophora fla- vescens Air, has been shown to have anti-inflammation, immune-suppressive, anti-tumor, and anti-hepatic fibrosis activities. However, the pharmacological effects of MT still need to be strengthened due to its relatively low efficacy and short half-life. In the present study, we report a more effective thio derivative of MT, MD-1, and its inhibitory effects on the activation of hepatic stellate cells （HSCs） in both cell culture and animal models. Cytological experiments showed that MD-1 can inhibit the proliferation of HSC-T6 cells with a half-maximal inhibitory concentration （ICs0） of 62 pmollL. In addition, MD-1 more strongly inhibits the migration of HSC-T6 cells compared to MT and can more effectively induce G0/G1 arrest and apoptosis. Investigating the biological mechanisms underlying anti-hepatic fibrosis in the presence of MD-I, we found that MD-I can bind the epidermal growth factor receptor （EGFR） on the surface of HSC-T6 cells, which can further inhibit the phospho- rylaUon of EGFR and its downstream protein kinase B （Akt）, resulting in decreased expression of cyclin D1 and eventual inhibition of the activation of HSC-T6 cells. Furthermore, in rats with dimethylnitrosamine （DMN）- induced hepatic fibrosis, MD-1 slowed the development and progression of hepatic fibrosis, protecting hepatic parenchymal cells and improving hepatic functions. Therefore, MD-1 is a potential drug for anti-hepatic fibrosis.

关键词： matrine derivative hepatic stellate cellhepatic fibrosis epidermal growth factor receptor signaltransduction pathway

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Shell-model study on properties of proton dripline nuclides with Z,N=30-50 including uncertainty analysis

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Chinese Physics C 2022年第8期46卷 196-210页

作者： bo-Shuai cai Guang-Shang Chen Cen-Xi Yuan Jian-Jun He Sino-French Institute of Nuclear Engineering and Technology Sun Yat-Sen UniversityZhuhai 519082China Key Laboratory of Beam Technology and Materials Modification of Ministry of Education College of Nuclear Science and TechnologyBeijing Normal UniversityBeijing 100875China Beijing Radiation Center Beijing 100875China

The binding and proton separation energies of nuclides with Z,N=30-50 are investigated based on the shell model,with an uncertainty analysis via statistical *** formulas are used to obtain the binding and proton separation energies according to shell-model *** non-parametric bootstrap method is applied to establish an uncertainty decomposition and recomposition ***,this is used to estimate the stability of proton(s) emission for each *** formulas for calculating the binding energies with a systematic uncertainty of~0.3 Me V are proposed,and a reliable extrapolation ability is *** binding energy formulas deduce similar forms for their respective S_(p) and S_(2 p) energies,which predict the extension of the nuclear boundary of this region.A good description of the binding and proton separation energies is *** one-and twoproton separation energies and partial half-lives of proton emission are predicted,thus revealing a new ***,there are 30 unstable nuclides predicted to be bound against proton(s)-*** nuclear properties will be useful in nuclear astrophysics.

关键词： shell model proton dripline uncertainty analysis

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全自动酶标免疫分析仪的技术原理与故障案例分析

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中国医学装备 2024年第5期21卷 197-201页

作者：徐炜新陶苗苗蔡波张惠琴孙杰上海健康医学院附属嘉定区中心医院检验科嘉定201800

分析全自动酶标免疫分析仪的技术原理及典型故障案例,以提升全自动酶标免疫分析仪的使用效果。通过微粒子酶免疫分析(MEIA)技术完成酶免试验,以主定标、标准定标、定性定标及定标液修正为全自动酶标免疫分析仪的定标方式,提升酶免试验... 详细信息

分析全自动酶标免疫分析仪的技术原理及典型故障案例,以提升全自动酶标免疫分析仪的使用效果。通过微粒子酶免疫分析(MEIA)技术完成酶免试验,以主定标、标准定标、定性定标及定标液修正为全自动酶标免疫分析仪的定标方式,提升酶免试验分析精度。通过分析全自动酶标免疫分析仪使用中遇到的洗板机、开机初始化报警、启动软盘、加样臂和滤光器等典型故障案例,提出故障解决应对措施,为全自动酶标免疫分析仪后期维修与管理提供参考。

关键词：全自动酶标免疫分析仪技术原理故障微粒子酶免疫分析(MEIA)技术荧光物强度

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Hierarchical porous carbon heterojunction flake arrays derived from metal organic frameworks and ionic liquid for H2O2 electrochemical detection in cancer tissue

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Nano Research 2021年第5期14卷 1335-1343页

作者： Yan Zhang Qiying Lv Kai Chi Qilin Li Huiling Fan bo cai Fei Xiao Shuai Wang Zheng Wang Lin Wang Union Hospital Tongji Medical CollegeHuazhong University of Science and TechnologyWuhan430022China Key Laboratory of Material Chemistry for Energy Conversion and Storage Ministry of EducationHubei Key Laboratory of Material Chemistry and Service FailureSchool of Chemistry and Chemical EngineeringHuazhong University of Science and TechnologyWuhan430074China

The development of hierarchical nanostructure is demonstrated as an effective strategy to improve catalytic activity and stability of ***,a novel leaf-like hierarchically porous heterojunction flake arrays(FAs),integrated graphitic N-doped carbon(NC)with amorphous B,N-doped carbon(BNC),has been designed and grown on flexible carbon fiber(CF)using metal-organic framework(MOF)FAs and green ionic liquids as *** hierarchical heterojunction structure possesses micro-and nano-scaled pores,large surface areas,and exposed high-density catalytic active sites,which enhances electronic conductivity and offers accessible transport channels for effectively decreasing mass transport *** results of discrete Fourier transform(DFT)calculations and experiments also suggest that the catalytic activity has been promoted by the heterojunction structure through narrowing the banding ***,the resultant nanohybrid microelectrode exhibits remarkable electrochemical sensing performance towards H2O2 with a low detection limit of 50 nM,and a high sensitivity of 213μA×mM-1×cm-2,as well as good anti-interference *** practical application of nanohybrid fiber microelectrode has been explored by real-time monitoring H2O2 released from live colon cells and surgically-resected fresh colon cancer tissue,which can provide important information for the identification of different types of cells as well as distinguish cancer cells from normal *** believe this research will pave the way towards the development of advanced carbon nanomaterials for application in the fields of electrochemistry,biosensing,and cancer diagnosis.

关键词： carbon heterojunction structure hierarchical flake arrays heteroatoms doping electrochemical sensor cancer biomarker detection

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