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Development of a convolutional neural network based geomechanical upscaling technique for heterogeneous geological reservoir

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第6期16卷 2111-2125页

作者： Zhiwei Ma Xiaoyan Ou bo Zhang Earth and Environmental Sciences Division Los Alamos National LaboratoryLos AlamosUSA Civil and Environmental Engineering University of AlbertaEdmontonCanada

Geomechanical assessment using coupled reservoir-geomechanical simulation is becoming increasingly important for analyzing the potential geomechanical risks in subsurface geological ***,a robust and efficient geomechanical upscaling technique for heterogeneous geological reservoirs is lacking to advance the applications of three-dimensional(3.)reservoir-scale geomechanical simulation considering detailed geological ***,we develop convolutional neural network(CNN)proxies that reproduce the anisotropic nonlinear geomechanical response caused by lithological heterogeneity,and compute upscaled geomechanical properties from CNN *** CNN proxies are trained using a large dataset of randomly generated spatially correlated sand-shale realizations as inputs and simulation results of their macroscopic geomechanical response as *** trained CNN models can provide the upscaled shear strength(R^(2)>0.949),stress-strain behavior(R^(2)>0.925),and volumetric strain changes(R^(2)>0.958)that highly agree with the numerical simulation results while saving over two orders of magnitude of computational *** is a major advantage in computing the upscaled geomechanical properties directly from geological realizations without the need to perform local numerical simulations to obtain the geomechanical *** proposed CNN proxybased upscaling technique has the ability to(1)bridge the gap between the fine-scale geocellular models considering geological uncertainties and computationally efficient geomechanical models used to assess the geomechanical risks of large-scale subsurface development,and(2)improve the efficiency of numerical upscaling techniques that rely on local numerical simulations,leading to significantly increased computational time for uncertainty quantification using numerous geological realizations.

关键词： Upscaling Lithological heterogeneity Convolutional neural network(CNN) Anisotropic shear strength Nonlinear stressestrain behavior

Impact of Hinterland Manufacturing on the Development of Container Ports: Evidence from the Pearl River Delta, China

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Chinese Geographical Science 2024年第5期34卷 886-898页

作者： HONG Haolin WANG bo XUE Desheng School of Geography and Planning Sun Yat-sen UniversityGuangzhou 510006China

Container ports and hinterland manufacturing are two important forces of the local participation in economic *** study,taking the Pearl River Delta(PRD),China with an export-oriented economy as an example,applies Huff and panel regres-sion models to evaluate the impact of hinterland manufacturing on the development of container ports during the period of 1993.*** results show that 1)the spatial patterns of hinterlands for hub ports help to determine the distribution range and scale of economic variables that affect port throughput;2)the hinterland’s gross manufacturing output has universally positive influence on port through-put,wherein export-oriented processing and the entire manufacturing industry have significantly positive impact on port throughput in 1993.2011 and 2001–2019,respectively;3.the two internal structural factors related to an export-oriented economy,labor-intensive sectors and foreign-funded terminals,have positively moderate the direct influence of hinterland manufacturing on port *** results highlight the importance of local context in understanding port-manufacturing relationship in developing *** on our findings,policy implications are further proposed to enhance port network organization in PRD.

关键词： container ports hinterland manufacturing local development context Huff model panel regression model Pearl River Delta(PRD),China

A combinatorial synthesis method for identification of orally bioavailable cyclic peptide

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Science China Chemistry 2024年第8期67卷 2429-2430页

作者： Zhenzhen Liu Li Liu bo Tang College of Chemistry Chemical Engineering and Materials ScienceKey Laboratory of Molecular and Nano ProbesMinistry of EducationCollaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of ShandongInstitutes of Biomedical SciencesShandong Normal UniversityJinan 250014China Laoshan Laboratory Qingdao 266237China

Cyclic peptides are a type of polypeptide with macrocyclic structure formed by canonical and non-canonical amino *** to their rigid conformation and large surface area,cyclic peptides typically exhibit high binding affinity and specificity with target proteins,particularly those considered undruggable by traditional small molecule drugs,such as protein-protein interactions[1].Additionally,they are convenient to be chemical modified to improve the pharmacological or pharmacokinetic properties.

关键词： properties. canonical synthesis

Chemical modification of barite for improving the performance of weighting materials for water-based drilling fluids

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Petroleum Science 2024年第1期21卷 551-566页

作者： Li-Li Yang Ze-Yu Liu Shi-bo Wang Xian-bo He Guan-Cheng Jiang Jie Zhang MOE Key Laboratory of Petroleum Engineering State Key Laboratory of Petroleum Resources and ProspectingChina University of Petroleum(Beijing)Changping DistrictBeijing102249China MOE Key CNPC Drilling Research Institute Changping DistrictBeijing102206China

With increasing drilling depth and large dosage of weighting materials,drilling fluids with high solid content are characterized by poor stability,high viscosity,large water loss,and thick mud cake,easier leading to reservoir damage and wellbore *** this paper,micronized barite(MB)was modified(mMB)by grafting with hydrophilic polymer onto the surface through the free radical polymerization to displace conventional API barite *** suspension stability of water-based drilling fluids(WBDFs)weighted with API barite:mMB=2:1 in 600 g was significantly enhanced compared with that with API barite/WBDFs,exhibiting the static sag factor within 0.54 and the whole stability index of *** viscosity and yield point reached the minimum,with a reduction of more than 40%compared with API barite only at the same *** multi-stage filling and dense accumulation of weighting materials and clays,filtration loss was decreased,mud cake quality was improved,and simultaneously it had great reservoir protection performance,and the permeability recovery rate reached 87%.In addition,it also effectively improved the lubricity of *** sticking coefficient of mud cake was reduced by 53.4%,and the friction coefficient was ***,mMB can serve as a versatile additive to control the density,rheology,filtration,and stability of WBDFs weighted with API barite,thus regulating comprehensive performance and achieving reservoir protection *** work opened up a new path for the productive drilling of extremely deep and intricate wells by providing an efficient method for managing the performance of high-density WBDFs.

关键词： Drilling fluids Weighting materials Filtration control Reservoir protection Stability property

Risk factors for lymph node metastasis in superficial esophageal squamous cell carcinoma

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World Journal of Gastroenterology 2024年第13期30卷 1810-1814页

作者： Yan-bo Yu Department of Gastroenterology Laboratory of Translational GastroenterologyQilu HospitalShandong UniversityJinan 250012Shandong ProvinceChina

In this editorial,we comment on the article by Wang et al published in the recent issue of the World Journal of Gastroenterology in *** focused on identifying risk factors for lymph node metastasis(LNM)in superficial esophageal squamous cell carcinoma(SESCC)patients and how to construct a simple and reliable clinical prediction model to assess the risk of LNM in SESCC patients,thereby helping to guide the selection of an appropriate treatment *** current standard treatment for SESCC is radical esophagectomy with lymph node ***,esophagectomy is associated with considerable morbidity and *** resection(ER)offers a safer and less invasive alternative to surgical resection and can enable the patient's quality of life to be maintained while providing a satisfactory ***,since ER is a localized treatment that does not allow for lymph node dissection,the risk of LNM in SESCC limits the effectiveness of *** LNM status can aid in determining whether patients with SESCC can be cured by ER without the need for additional *** studies have shown that tumor size,macroscopic type of tumor,degree of differentiation,depth of tumor invasion,and lymphovascular invasion are factors associated with LNM in patients with *** addition,tumor budding is commonly associated with LNM,recurrence,and distant metastasis,but this topic has been less covered in previous *** comprehensively evaluating the above risk factors for LNM,useful evidence can be obtained for doctors to select appropriate treatments for SESCC patients.

关键词： Superficial esophageal squamous cell carcinoma Endoscopic resection Lymph node metastasis Risk factors Tumor budding Predictive model

Analysis of thermal management and anti-mechanical abuse of multi-functional battery modules based on magneto-sensitive shear thickening fluid

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Applied Mathematics and Mechanics(English Edition) 2024年第3期45卷 529-542页

作者： Yang XIONG bo LU Yicheng SONG Junqian ZHANG Shanghai Key Laboratory of Mechanics in Energy Engineering Shanghai Frontier Science Center of MechanoinformaticsShanghai Institute of Applied Mathematics and MechanicsSchool of Mechanics and Engineering ScienceShanghai UniversityShanghai 200444China Zhejiang Laboratory Hangzhou 311100China

Electric vehicles(EVs)have garnered significant attention as a vital driver of economic growth and environmental ***,ensuring the safety of high-energy batteries is now a top priority that cannot be overlooked during large-scale *** paper proposes an innovative active protection and cooling integrated battery module using smart materials,magneto-sensitive shear thickening fluid(MSTF),which is specifically designed to address safety threats posed by lithium-ion batteries(LIBs)exposed to harsh mechanical and environmental *** theoretical framework introduces a novel approach for harnessing the smoothed-particle hydrodynamics(SPH)methodology that incorporates the intricate interplay of non-Newtonian fluid behavior,capturing the fluid-structure coupling inherent to the *** approach is further advanced by adopting an enhanced Herschel-Bulkley(H-B)model to encapsulate the intricate rheology of the MSTF under the influence of the magnetorheological effect(MRE)and shear thickening(ST)*** simulation results show that in the case of cooling,the MSTF is an effective cooling medium for rapidly reducing the *** terms of mechanical abuse,the MSTF solidifies through actively applying the magnetic field during mechanical compression and impact within the battery module,resulting in 66%and 61.7%reductions in the maximum stress within the battery jellyroll,and 3..1%and 23.reductions in the reaction force,*** mechanism effectively lowers the risk of short-circuit *** groundbreaking concepts unveiled in this paper for active protection battery modules are anticipated to be a valuable technological breakthrough in the areas of EV safety and lightweight/integrated design.

关键词： magneto-sensitive shear thickening fluid(MSTF) battery module impact protection temperature control integrated design

Materials advancements for the safety and patency of implantable cardiovascular devices

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Nano Research 2024年第10期17卷 8977-8989页

作者： Zulmari Silva Pedraza bo Liu Xudong Wang Department of Materials Science and Engineering University of Wisconsin−MadisonMadisonWisconsin 53706USA Departments of Cell and Regenerative Biology University of Wisconsin-MadisonMadisonWisconsin 53705USA

Implantable cardiovascular devices have revolutionized the management of cardiovascular diseases,significantly enhancing patients’quality of *** the increasing demand of cardiac implantable electronic devices,the imperative for novel device development is *** review article first elaborates the mechanisms underlying foreign body response and infection,elucidating the complex interplay between implanted constructs and host *** discussion then focuses on current advancements in materials science and engineering aimed at mitigating these *** innovations,such as drugeluting materials,surface modifications,and biomimetic materials,are explored as strategies to modulate these responses and to prevent fibrotic or thrombotic complications and ***,future directions in materials development for implantable cardiovascular devices are *** addressing safety and patency concerns through innovative material strategies,this article aims to guide the research and development of advanced materials for both current and future cardiovascular implantable devices,ultimately improving patient outcomes and advancing cardiovascular disease treatment.

关键词： biomaterials implantable devices cardiovascular diseases implantable materials

The unique spontaneous polarization property and application of ferroelectric materials in photocatalysis

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Nano Research 2024年第5期17卷 3571-3585页

作者： Jinghua An Chang Xu Lu Li bo Tang College of Chemistry Chemical Engineering and Materials ScienceKey Laboratory of Molecular and Nano ProbesMinistry of EducationCollaborative Innovation Center of Functionalized Probes for Chemical Imaging in University of ShandongInstitute of Molecular and Nano ScienceShandong Normal UniversityJinan 250014China Laoshan Laboratory 168 Wenhai Middle RdAoshanwei JimoQingdao 266237China

The unique spontaneous polarization property of ferroelectric material makes it to be a special catalyst in *** spontaneous polarization property can induce the formation of built-in electric field,which can improve the separation of photoelectrons and holes to affect photocatalytic *** internal electric field induced by spontaneous polarization can be influenced by multiple factors such as the morphology,the concentration of defect,the type of doped heteroatoms,as well as the composition of ***,the preparation method,pretreating temperature,the strength of prepolarized external electric field of ferroelectric-based photocatalysts as well as the strength of external mechanical force or external magnetic field in photocatalytic reactions can influence the photocatalytic effectivity via influencing spontaneous polarization-induced internal electric ***,it is urgently to unveil the mystery of structure-activity relationships for ferroelectric materials-based photocatalysts,which is usually *** this in mind,this review was provided for the role of various complex influencing factors on ferroelectric materials-based photocatalysis based on the latest advancement in the fields of new energy development,environmental *** the beginning,the basic structure and properties of ferroelectric material are ***,popular synthesis methods of ferroelectric-based photocatalysts are *** that,two main mechanisms of ferroelectric photocatalysis are *** research progress of ferroelectric photocatalysis is then given emphatically according to the classification of photocatalytic ***,the problems existing nowadays and the challenges facing in the future on the application of ferroelectric materials-based photocatalysts are outlined in the summary and outlook section.

关键词： spontaneous polarization photocatalysis ferroelectric separation of electrons and holes

Thermodynamic Performance Analysis of E/F/H-Class Gas Turbine Combined Cycle with Exhaust Gas Recirculation and Inlet/Variable Guide Vane Adjustment under Part-Load Conditions

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Journal of Thermal Science 2024年第1期33卷 348-367页

作者： LI Keying CHI Jinling WANG bo ZHANG Shijie Key Lab of Advanced Energy and Power Institute of Engineering ThermophysicsChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China School of Mechanical Electronic&Information Engineering China University of Mining&Technology-BeijingBeijing 100083China

Exhaust gas recirculation control(EGRC),an inlet air heating technology,can be utilized in combination with inlet/variable guide vane control(IGV/VGVC) and fuel flow control(FFC) to regulate the load,thereby effectively improving the part-load(i.e.,off-design) performance of the gas turbine combined cycle(GTCC).In this study,the E-,F-,and H-Class EGR-GTCC design and off-design system models were established and validated to perform a comparative analysis of the part-load performance under the EGR-IGV-FFC and conventional IGV-FFC strategies in the E/F/H-Class *** show that EGR-IGV-FFC has considerable potential for the part-load performance enhancement and can show a higher combined cycle efficiency than IGV-FFC in the E-,F-,and H-Class ***,the part-load performance improvement in the corresponding GTCC was weakened for the higher class of the gas turbine because of the narrower load range of EGR action and the deterioration of the gas turbine ***,EGR-IGV-FFC was inferior to IGV-FFC in improving the performance at loads below 50% for the H-Class *** results obtained in this paper could help guide the application of EGR-IGV-FFC to enhance the part-load performance of various classes of GTCC systems.

关键词： E/F/H-Class gas turbine combined cycle performance improvement part-load conditions exhaust gas recirculation inlet/variable guide vane