检索结果-南通市图书馆

Combined spatial frequency spectroscopy analysis with visible resonance Raman for optical biopsy of human brain metastases of lung cancers

引用

Journal of Innovative Optical Health Sciences 2019年第2期12卷 93-104页

作者： Yan Zhou Cheng-Hui Liu Yang Pu binlin wu Thien An Nguyen Gangge Cheng Lixin Zhou Ke Zhu Jun Chen Qingbo Li Robert R.Alfano The Air Force Medical Center PLANo.30 FuchengluHaidian DistrictBeijing 100142P.R.China Department of Physics The City College of the City University of New York Institute of Ultrafast Spectroscopy and Lasers NY 10031USA Physics Department and CSCU Center for Nanotechnology Southern Connecticut State University 501 Crescent Street New HavenCT 06515USA Beijing Cancer Hospital No.52Fuchenglu Haidian DistrictBeijing 100142P.R.China Institute of Physics Chinese Academy of Sciences(CAS)Beijing 100190P.R.China Department of Cardiology Tianjin Medical University General Hospital Tianjin 300052P.R.China Beihang University Xueyuan Road No.37Haidian DistrictBeijing 100191P.R.China

The purpose of this study is to examine optical spatial frequency spectroscopy analysis(SFSA)combined with visible resonance Raman(VRR)spectroscopic method,for thefirst time,to discriminate human brain metastases of lung cancers adenocarcinoma(ADC)and squamous cell carcinoma(SCC)from normal tissues.A total of 31 label-free micrographic images of three type of brain tissues were obtained using a confocal micro-Raman spectroscopic *** spectra of the corresponding samples were synchronously collected using excitation wavelength of 532 nm from the same sites of the *** SFSA method,the difference in the randomness of spatial frequency structures in the micrograph images was analyzed using Gaussian *** standard deviations,calculated from the spatial frequencies of the micrograph images were then analyzed using support vector machine(SVM)*** key VRR biomolecularfingerprints of carotenoids,tryptophan,amide II,lipids and proteins(methylene/methyl groups)were also analyzed using SVM *** three types of brain tissues were identified with high accuracy in the two approaches with high *** results show that SFSA–VRR can potentially be a dual-modal method to provide new criteria for identifying the three types of human brain tissues,which are on-site,real-time and label-free and may improve the accuracy of brain biopsy.

关键词： Spatial frequency spectroscopy analysis(SFSA) visible resonance Raman(VRR) human brain metastatic lung cancer photomicrograph image support vector machine(SVM)

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A pilot study for distinguishing basal cell carcinoma from normal human skin tissues using visible resonance Raman spectroscopy

引用

Journal of Cancer Metastasis and Treatment 2019年第1期4卷 41-54页

作者： Cheng-hui Liu binlin wu Laura ASordillo Susie Boydston-White Vidyasagar Sriramoju ChunyuanZhang Hugh Beckman Lin Zhang Zhe Pei Lingyan Shi Robert RAlfano Institute for Ultrafast Spectroscopy and Lasers The City College of the City University of New YorkNew YorkNY 10031USA Physics Department and CSCU Center for Nanotechnology Southern Connecticut State UniversityNew HavenCT 06515USA Department of Electrical Engineering The Grove School of EngineeringThe City College of the City University of New YorkNew YorkNY 10031USA Science Department City University of New YorkBorough of Manhattan Community CollegeNew YorkNY 10007-1097USA Bermuda Village Dr. Boca RatonFlorida 33487-1041USA517150 Department of Chemistry Columbia UniversityNew YorkNY 10027USA

Aim: The aim of the study is to test visible resonance Raman (VRR) spectroscopy for rapid skin cancer diagnosis,and evaluate its effectiveness as a new optical biopsy method to distinguish basal cell carcinoma (BCC) from normal skin ***: The VRR spectroscopic technique was undertaken using 532 nm excitation. Normal and BCC human skin tissue samples were measured in seconds. The molecular fingerprints of various native biomolecules as biomarkers were analyzed. A principal component analysis - support vector machine (PCA-SVM) statistical analysis method based on the molecular fingerprints was developed for differentiating BCC from normal skin ***: VRR provides a rapid method and enhanced Raman signals from biomolecules with resonant and nearresonant absorption bands as compared with using a near-infrared excitation light source. The VRR technique revealed chemical composition changes of native biomarkers such as tryptophan, carotenoids, lipids and *** VRR spectra from BCC samples showed a strong enhancement in proteins including collagen type I combined with amide I and amino acids, and a decrease in carotenoids and lipids. The PCA-SVM statistical analysis based on the molecular fingerprints of the biomarkers yielded a 93.0% diagnostic sensitivity, 100% specificity, and 94.5%accuracy compared with histopathology ***: VRR can enhance molecular vibrational modes of various native biomarkers to allow for very fast display of Raman modes in seconds. It may be used as a label-free molecular pathology method for diagnosis of skin cancer and other diseases and be used for combined treatment with Mohs surgery for BCC.

关键词： Visible resonance Raman spectroscopy human skin basal cell carcinoma principal componentanalysis supports vector machine molecular fingerprints tryptophan carotenoids

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

心理健康情境体验式教学初探

引用

中国冶金教育 2009年第3期14卷 69-71页

作者：吴炳麟福建理工学校福建福州350002

传统教育模式以课堂为中心、以课本为中心、以教师为中心,导致学生的参与、体验相对较差,普遍存在学习动机不足、学习兴趣下降的现象。针对这些问题,通过"情境—体验—认知"模式来实现心理健康教育与情境体验相结合,促进学生全面发展和... 详细信息

传统教育模式以课堂为中心、以课本为中心、以教师为中心,导致学生的参与、体验相对较差,普遍存在学习动机不足、学习兴趣下降的现象。针对这些问题,通过"情境—体验—认知"模式来实现心理健康教育与情境体验相结合,促进学生全面发展和身心协调。

关键词：心理健康情境体验

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

“雷州石狗”传统文化美育教育融入儿童书籍设计探究

引用

艺术与设计（理论版） 2021年第8期 45-47页

作者：罗小燕吴炳玲广东海洋大学广东湛江524088

文章探讨将"雷州石狗"传统文化元素融入儿童书籍设计中,使我国优秀的传统文化"雷州石狗"与儿童书籍设计相结合以实现创新。旨在提高我国青少年儿童对中华优秀传统文化的认识,培养他们对本民族文化的认同感。通过把"雷州石狗"传统文化美... 详细信息

文章探讨将"雷州石狗"传统文化元素融入儿童书籍设计中,使我国优秀的传统文化"雷州石狗"与儿童书籍设计相结合以实现创新。旨在提高我国青少年儿童对中华优秀传统文化的认识,培养他们对本民族文化的认同感。通过把"雷州石狗"传统文化美育教育融入儿童书籍的互动式设计中来进行设计创新,以设计符合现代儿童心理和生理发展需求的儿童书籍,打破传统儿童书籍设计局限,设计出能让儿童在阅读中获得快乐,促进身体健康成长,并不断接受传统文化美的教育的书籍,从而培养青少年儿童对我国优秀传统文化的自信。

关键词：雷州石狗美育儿童书籍互动设计

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

MsS超声导波检测系统在桥梁缆索检测中的应用

引用

金属制品 2023年第6期49卷 48-51页

作者：吴彬林何岩王敏中钢集团郑州金属制品研究院股份有限公司河南郑州450001

CJJ 99—2017《城市桥梁养护技术标准》规定,应每3年对桥梁缆索护层破损状况及钢丝锈蚀情况进行全面检测,可采用无损探伤或剥开已损坏的护层等方法检查,并测量锈蚀钢丝的实际有效面积。而MsS超声导波检测技术作为一种可以快速发现构件... 详细信息

CJJ 99—2017《城市桥梁养护技术标准》规定,应每3年对桥梁缆索护层破损状况及钢丝锈蚀情况进行全面检测,可采用无损探伤或剥开已损坏的护层等方法检查,并测量锈蚀钢丝的实际有效面积。而MsS超声导波检测技术作为一种可以快速发现构件内部存在截面损失的磁致伸缩超声导波检测方法,可实现大面积快速扫查,一次可以检测上百米的距离;检测灵敏度高,最高检测灵敏度能够达到截面积损失率的1%,可靠检测灵敏度能够达到截面积损失率的5%,当进行在线腐蚀检测与长期状态监测时,灵敏度能够达到截面积损失率的0.6%。

关键词：无损检测磁致伸缩效应超声导波桥梁缆索灵敏度

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Numerical and experimental research of the characteristics of concentration solar cells

引用

Frontiers in Energy 2021年第2期15卷 279-291页

作者： Zilong WANG Hua ZHANG binlin DOU Weidong wu Guanhua ZHANG Shanghai Key Laboratory of Multiphase Flow and Heat Transfer in Power Engineering School of Energy and Power EngineeringUniversity of Shanghai for Science and TechnologyShanghai 200093China

The development of automatic tracking solar concentrator photovoltaic systems is currently attracting growing *** concentration photovoltaic systems(HCPVs)combining triple-junction InGaP/lnGaAs/Ge solar cells with a concentrator provide high conversion *** mathematical model for triple-junction solar cells,having a higher efficiency and superior temperature characteristics,was established based on the one-diode equivalent circuit cell model.A paraboloidal concentrator with a secondary optic system and a concentration ratio in the range of 100X–150X along with a sun tracking system was developed in this *** GaInP/GalnAs/Ge triple-junction solar cell,produced by AZUR SPACE Solar Power,was also used in this *** solar cells produced by Shanghai Solar Youth Energy(SY)and Shenzhen Yinshengsheng Technology ***.(YXS)were used as comparison samples in a further comparative study at different concentration ratios(200X–1000X).A detailed analysis on the factors that influence the electrical output characteristics of the InGaP/lnGaAs/Ge solar cell was conducted with a dish-style concentrating photovoltaic *** results show that the short-circuit current(Isc)and the open-circuit voltage(Voc)of multi-junction solar cells increases with the increasing concentration ratio,while the cell efficiency(ηc)of the solar cells increases first and then decreases with increasing concentration *** increasing solar cell temperature,Isc increases,while Voc andηc decrease.A comparison of the experimental and simulation results indicate that the maximum root mean square error is less than 10%,which provides a certain theoretical basis for the study of the characteristics of triple-junction solar cell that can be applied in the analysis and discussion regarding the influence of the relevant parameters on the performance of high concentration photovoltaic systems.

关键词： concentration three-junction solar cell mathematical model electrical properties solar energy

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Phase Equilibrium Characteristics of CO_(2)and Ionic Liquids with[FAP]-Anion Used for Absorption-Compression Refrigeration Working Pairs

引用

Journal of Thermal Science 2021年第1期30卷 165-176页

作者： wu Weidong WANG Li LI Xiang LIU Hui ZHANG Hua DOU binlin School of Energy and Power Engineering University of Shanghai for Science and TechnologyShanghai 200093China

The study of the phase equilibrium characteristics of CO_(2)-ionic liquids(ILs)as new absorption-compression type refrigeration working pairs is of great *** kinds of ILs,i.e.,[emim][FAP],[bmim][FAP]and[hmim][FAP],were chosen as potential *** solubility of CO_(2)in these ILs was measured experimentally within 0 to 5.0 MPa at temperatures of 293.15 K to 333.15 K,and the effects of temperature,pressure,IL anion and cation structure and stirring action on CO_(2)solubility were also discussed and *** results showed that the longer alkyl chains in an identical IL family,the alkyl fluoride group in IL anions and the stirring action by a magnetic stirrer had positive effects on the solubility of CO_(2).In the three ILs,[hmim][FAP]possessed the best performance for CO_(2)absorption;the solubility of CO_(2)reached 0.7641 at a pressure of 5 MPa and temperature of 293.15 K,the maximum solubility measured in this *** CO_(2)-[hmim][FAP]binary mixture is recommended as a potentially applicable working pair for CO_(2)absorption-compression refrigeration systems.

关键词： CO_(2) ionic liquids(ILs) absorption-compression refrigeration working pair phase equilibrium tris(perfluoroalkyl)trifluorophosphate anions([FAP]^(-))

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Sex-dependent alterations in extracellular vesicles linking chronic spinal cord injury to brain neuroinflammation and neurodegeneration

引用

Neural Regeneration Research 2025年第2期20卷 483-484页

作者： Yun Li Junfang wu Department of Anesthesiology&Shock Trauma and Anesthesiology Research(STAR)CenterUniversity of Maryland School of MedicineBaltimoreMDUSA

Traumatic spinal cord injury(SCI)is a devastating exogenous injury with long-lasting consequences and a leading cause of death and disability *** in assistive technology,rehabilitative interventions,and the ability to identify and intervene in secondary conditions have significantly increased the long-term survival rate of SCI patients,with some people even living well into their seventh or eighth *** survival changes have led neurotrauma researchers to examine how SCI interacts with brain *** health and epidemiological data showed that patients with long-term SCI can have a lower life expectancy and quality of life,along with a higher risk of comorbidities and complications.

关键词： alterations inflammation injury

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

流行性出血热并发瘫痪2例报告

引用

中华传染病杂志 1986年第1期4卷 55-55页

作者：吴彬林山西省运城地区传染病医院

流行性出血热(EHF)并发四肢弛缓性瘫痪少见,1982年我们曾见二例,现报告如下.[例1]女,32岁.因发热、四肢活动不灵5天,于3月17日入院.患者于13日突然发热,畏寒,头痛,周身酸困,四肢伸展屈曲不灵,14日神志恍惚,谵语躁动,发病来仅排尿一次.

关键词：流行性出血热弛缓性瘫痪现报告如下四肢神志恍惚发热畏寒头痛屈曲排尿活动患者发病

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Gut microbiota shifts in hepatitis B-related portal hypertension after transjugular intrahepatic portosystemic shunt:Mechanistic and clinical implications

引用

World Journal of Gastroenterology 2025年第3期31卷 134-137页

作者： Qi-Rong Jiang Da-wu Zeng Department of Hepatology Hepatology Research InstituteThe First Affiliated HospitalFujian Medical UniversityFuzhou 350005Fujian ProvinceChina Department of Infectious Diseases The First Affiliated Hospital of Fujian Medical UniversityFuzhou 350004Fujian ProvinceChina

In this article,we provide commentary on the recent article by Zhao et *** focus on the shifts in the gut microbiota of patients with hepatitis B virus(HBV)-associated cirrhosis/portal hypertension(PH)following transjugular intrahepatic portosystemic shunt(TIPS)and the implications for understanding the mechanisms,diagnosis,and *** comparing the gut microbiota composition and dynamic changes before and after TIPS in patients with and without hepatic encephalopathy,the authors found an increase in non-probiotic bacteria in those who developed hepatic encephalopathy post-TIPS,with Morganella species present only in the hepatic encephalopathy *** gut microbiota changes post-TIPS among patients without the occurrence of hepatic encephalopathy suggest potential therapeutic benefits through prophylactic microbiome ***,the specific gut microbiota alterations may hold promise to predict the risk of hepatic encephalopathy in individuals undergoing TIPS for HBVrelated *** these promising findings,future studies are needed to address limitations,including a small sample size,a relatively short evaluation period for gut microbiota alterations,the absence of data on dynamic alterations in gut microbiota post-TIPS and their correlation with blood ammonia levels,and the lack of validation in animal *** conclusion,Zhao et al's study has shed new light on the link of gut microbiota with post-TIPS hepatic encephalopathy,potentially through the intricate gut-liver axis,and has important clinical implications for improving the management of patients with HBV-related PH.

关键词： Hepatitis B virus Cirrhosis Portal hypertension Hepatic encephalopathy Transjugular intrahepatic portosystemic shunt Gut microbiota

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：