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Dietary copper requirement of broilers fed a corn-soybean meal diet during 22—42 d of age

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Animal Nutrition 2024年第1期16卷 96-104页

作者： Ling Zhu Wei Wu bingxin Wu Yun Hu Liyang Zhang Weiyun Zhang Tingting Li Xiaoyan Cui Feiyu Gao Ding Li Xugang Luo Shengchen Wang Poultry Mineral Nutrition Laboratory College of Animal Science and TechnologyYangzhou University Mineral Nutrition Research Division State Key Laboratory of Animal NutritionInstitute of Animal ScienceChinese Academy of Agricultural Sciences

This research was to assess the dietary copper(Cu) requirement of broiler chickens fed a practical cornsoybean meal diet during 22—42 d of age. A total of 288 numbered Arbor Acres male broilers at 22 d of age were randomly allotted 6 treatments with 8 replicate cages(6 broilers per cage) per *** were fed a Cu-unsupplemented corn-soybean meal basal diet(control, containing 7.36 mg Cu/kg) or the basal diet added with 3, 6, 9, 12, or 15 mg Cu/kg from CuSO4·5H2O for 21 d. Quadratic,asymptotic and broken-line models were fitted and the best fitted models were selected to determine dietary Cu requirements. The results revealed that the contents of Cu in serum and liver, m RNA expression levels of Cu-and zinc-containing superoxide dismutase(CuZnSOD) in liver and monoamine oxidase b(MAO B) in heart, as well as protein expression level of CuZnSOD in liver were affected(P < 0.05) by supplemental Cu levels, and the above indices varied linearly and quadratically(P < 0.05)with increasing Cu levels. Dietary Cu requirements assessed according to the best fitted broken-line models(P < 0.05) of the above indexes were 10.45—13.81 mg/kg. It was concluded that mRNA expression levels of CuZnSOD in liver and MAO B in heart, as well as liver CuZnSOD protein expression level were new specific sensitive biomarkers for estimating dietary Cu requirements, and the dietary Cu requirement was recommended to be 14 mg/kg to support Cu metabolic needs related to key Cucontaining enzymes in broilers fed the corn-soybean meal diet during 22—42 d of age, which was higher than the dietary Cu requirement(8 mg/kg) for broilers at the corresponding stage suggested by the Chinese Feeding Standard of Chicken.

关键词： Copper Copper content Gene expression of copper-containing enzyme Requirement Broiler

网络社会价值秩序建构的路径选择基于网络社会思潮的视角

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实事求是 2022年第6期 77-83页

作者：刘秉鑫山东社会科学院马克思主义研究院山东济南250002 华东政法大学经济法学科博士后流动站上海201620

任何社会思潮都是一定时代的社会环境的产物,网络社会思潮是现实空间和网络空间社会基础交叉作用下的思想现象,更是寻求价值或观念认同的社会运动。网络社会的出现深刻变革着当前的舆论生态、媒体格局、传播方式,正确认识网络社会思潮... 详细信息

任何社会思潮都是一定时代的社会环境的产物,网络社会思潮是现实空间和网络空间社会基础交叉作用下的思想现象,更是寻求价值或观念认同的社会运动。网络社会的出现深刻变革着当前的舆论生态、媒体格局、传播方式,正确认识网络社会思潮的本质规律,寻求网络社会价值秩序建构的有效路径,有利于提高党和政府的用网治网水平以及更好把握网络社会思潮的政治方向、舆论导向、价值取向。

关键词：网络社会价值秩序社会思潮

Clinical efficacy and gene chip expression analysis of Shenzhu Guanxin recipe granules(参术冠心方颗粒) in patients with intermediate coronary lesions

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Journal of Traditional Chinese Medicine 2024年第3期44卷 545-553页

作者： JIN Xiao WU bingxin LIN Miaoyang ZHONG Biying LIN Luoqi XU Danping Department of Traditional Chinese Medicine the First Affiliated Hospital of Jinan UniversityJinan University Department of Cardiology Second Clinical College of Guangzhou University of Chinese Medicine Department of Traditional Chinese Medicine the Eighth Affiliated HospitalSun Yat-Sen University

OBJECTIVE: To evaluate the clinical efficacy and safety of Shenzhu Guanxin recipe granules(参术冠心颗粒, SGR) in treating patients with intermediate coronary lesions(ICL), and to investigate the potential mechanism though a transcriptome sequencing approach. METHODS: ICL patients with Qi deficiency and phlegm stasis were adopted and randomly assigned to a case group or a control by random number generator in a 1∶1 randomization ratio to evaluate the clinical efficacy. RESULTS: There was no significant difference between the two groups in coronary computed tomography angiography related indexes in the two groups before and after intervention. Through the gene chip expression analysis, it is finally concluded that there are 355 differential mRNAs(190 up-regulated genes and 165 down regulated genes) when compared the SGR group and placebo group. Through protein-protein interaction network analysis of differentially expressed genes, 10 hub genes were finally obtained: CACNA2D2, CACNA2D3, DNAJC6, FGF12, SGSM2, CACNA1G, LRP6, KIF25, OXTR, UPB1. CONCLUSIONS: SGR combined with Western Medicine can be safely used to treat ICL patients with Qi deficiency and phlegm stasis. The possible mechanism of action and relevant gene loci and pathway were proposed.

关键词： Shenzhu Guanxin recipe granules deficiency and phlegm stasis gene expression profiling intermediate coronary lesions

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基于重叠网格的航行体水动力特性计算

兵器装备工程学报 2023年第1期44卷 54-58,167页

作者：韩守根杨岩刘丙鑫陶钢南京理工大学能源与动力工程学院南京210094 南京航空航天大学直升机传动技术重点实验室南京210016

利用重叠网格技术结合实验方法,研究了航行体跨界质过程中的阻力来源。将试验结果与仿真结果进行对比,得出该过程中的水动力及水动力系数变化趋势以及原因,结果表明:航行体在水下速度由25 m/s下降到9.7 m/s,水动力以及系数在航行体即将... 详细信息

利用重叠网格技术结合实验方法,研究了航行体跨界质过程中的阻力来源。将试验结果与仿真结果进行对比,得出该过程中的水动力及水动力系数变化趋势以及原因,结果表明:航行体在水下速度由25 m/s下降到9.7 m/s,水动力以及系数在航行体即将出水时刻达到最大值,分别为0.65 kN和0.184。出水过程水动力及力系数主要受水冢现象、浮力变化以及附连水质量变化影响而呈现波动并逐渐趋向于零,粘滞力是航行体完全出水后主要的流体阻力来源。该研究为水航行体减阻设计提供了参考依据。

关键词：流体动力多相流重叠网格阻力计算数值模拟

Frequency Regulation of VSC-MTDC System with Offshore Wind Farms

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Journal of Modern Power Systems and Clean Energy 2024年第1期12卷 275-286页

作者： Haoyu liu Chongru liu North China Electric Power University Beijing 102206China

Frequency regulation of voltage source converter-based multi-terminal high-voltage direct current(VSC-MTDC)system with offshore wind farms enhances the frequency stability by compensating the power for a disturbed AC ***,it is difficult to reasonably allocate frequency-regulation resources due to a lack of coordination mechanisms between wind farms and the MTDC ***,it is difficult for the frequency control of the wind farms to manage changes in wind speed;and the risk of wind-turbine stalls is ***,based on the kinetic energy of wind turbines and the power margin of the converters,the frequency-regulation capability of wind turbines is evaluated,and a dynamic frequency-support scheme considering the real-time frequency-support capability of the wind turbines and system frequency evolution is proposed to improve the frequency-support performance.A power adaptation technique at variable wind speeds is developed;the active power in the frequency-support stage and restoration stage is switched according to the wind speed.A hierarchical zoning frequency-regulation scheme is designed to use the frequency-regulation resources of different links in the MTDC system with wind *** simulation results show that the novel frequency-regulation strategy maintains frequency stability with wind-speed changes and avoids multiple frequency dips.

关键词： Wind generation voltage source converter-based multi-terminal high-voltage direct current(VSC-MTDC) frequency regulation cooperative control adaptive control variable wind speed

Wireless measurement of orthodontic forces in invisible aligners

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Medicine in Novel Technology and Devices 2024年第1期21卷 64-70页

作者： Siyu Wang bingxin Xu Xiaokang Wang Xinfang Li Bangzheng Pu Gui Chen Jianmin Han Shengzhao Xiao Yubo Fan Jiebo Li Key Laboratory of Biomechanics and Mechanobiology(Beihang University) Ministry of EducationInstitute of Medical PhotonicsBeijing Advanced Innovation Center for Biomedical EngineeringSchool of Biological Science and Medical EngineeringBeihang UniversityBeijing100191China Department of Orthodontics Peking University School and Hospital of Stomatology&.National Clinical Research Center for Oral Diseases&.National Engineering Laboratory for Digital and Material Technology of Stomatology&.Beijing Key Laboratory of Digital Stomatology&.Research Center of Engineering and Technology for Computerized Dentistry Ministry of HealthBeijing100081China Department of Dental Materials Peking University School and Hospital of Stomatology&National Center of Stomatology&National Clinical Research Center for Oral Diseases&National Engineering Laboratory for Digital and Material Technology of Stomatology&Beijing Key Laboratory of Digital Stomatology&Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health&NMPA Key Laboratory for Dental MaterialsBeijing100081China Department of Orthodontics Shanghai Ninth People's HospitalCollage of StomatologyShanghai Jiao Tong University School of MedicineNational Clinical Research Center for Oral DiseasesShanghai Key Laboratory of Stomatology&Shanghai Research Institute of StomatologyShanghaiChina

Invisible orthodontic treatment is an effective form of malocclusion treatment favored in recent *** magnitude of its orthodontic force has a crucial impact on the outcome of the treatment and has gained a high level of clinical ***,there are very few explorations of in vivo measurements of orthodontic force,and existing studies are limited to a large number of couplings,which are inconvenient for clinical *** this work,we developed a wireless flexible measurement system that allows quantitative measurement of the orthodontic force of an invisible aligner on a dental *** system is wireless,tiny,flexible,fast responding,and has a range suitable for the range of orthodontic *** show the difference in the orthodontic force applied to different tooth positions and the difference in the orthodontic force applied to different positions of the same *** addition,the system can evaluate the mechanical differences between aligners of different brands and materials as well as the deviation of fabrication *** system provides a test tool and evaluation method for future real-time assessment of clinical orthodontic forces.

关键词： Orthodontic forces Wireless measurement systems Flexible sensors Invisible orthodontics Performance evaluation Quantitative measurements

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两足教育机器人的历史发微与设计逻辑

现代远距离教育 2023年第4期 41-52页

作者：公雪刘秉新张蓉菲谢中取江南大学江苏无锡214000 东北师范大学吉林长春130000 南京理工大学江苏南京210000

随着人工智能技术发展,教育机器人衍生出新的两足形态并开始逐渐介入到新型智慧教育模式中,影响了传统的教与学方式。基于对两足教育机器人三个历史衍变阶段的梳理,以人机交互为切入点,选取ASIMO、NAO以及Alpha Ebot为典型代表,剖解两... 详细信息

随着人工智能技术发展,教育机器人衍生出新的两足形态并开始逐渐介入到新型智慧教育模式中,影响了传统的教与学方式。基于对两足教育机器人三个历史衍变阶段的梳理,以人机交互为切入点,选取ASIMO、NAO以及Alpha Ebot为典型代表,剖解两足教育机器人产品研发中应遵循本体形态、关键技术和智能要素的基本设计逻辑。据此发现两足教育机器人现阶段存在技术设计、操作逻辑、学生互动和应用场景等四个方面的教育适配性实践困境,从而提出构建协同平台、制定适用规约、加强人机交互以及聚焦学科融合等四条发展向路来纾解教师、家长、学生、社会及应用实践忧思,赋能教育生态数字化转型,以期推动“机器人+”背景下两足教育机器人产品在智慧教育生态中落地和应用。

关键词：两足教育机器人设计逻辑人工智能智慧教育人机交互

Fe-N-C core-shell catalysts with single low-spin Fe(Ⅱ)-N_(4)species for oxygen reduction reaction and high-performance proton exchange membrane fuel cells

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Journal of Energy Chemistry 2024年第6期93卷 538-546,I0013页

作者： Yan Wan Linhui Yu bingxin Yang Caihong Li Chen Fang Wei Guo Fang-Xing Xiao Yangming Lin Xiamen Key Laboratory of Rare Earth Photoelectric Functional Materials Xiamen Institute of Rare Earth MaterialsHaixi InstituteChinese Academy of SciencesXiamen 361021FujianChina CAS Key Laboratory of Urban Pollutant Conversion Institute of Urban EnvironmentChinese Academy of SciencesXiamen 361021FujianChina Fujian Institute of Research on the Structure of Matter Chinese Academy of SciencesFuzhou 350002FujianChina College of Materials Science and Engineering Fuzhou UniversityNew CampusMinhou 350108FujianChina College of Chemistry and Materials Science Fujian Normal UniversityFuzhou 350117FujianChina

Fe-N-doped carbon materials(Fe-N-C)are promising candidates for oxygen reduction reaction(ORR)relative to Pt-based catalysts in proton exchange membrane fuel cells(PEMFCs).However,the intrinsic contributions of Fe-N_(4)moiety with different chemical/spin states(e.g.D1,D2,D3)to ORR are unclear since various states coexist *** the present work,Fe-N-C core-shell nanocatalyst with single lowspin Fe(Ⅱ)-N_(4)species(D1)is synthesized and identified with ex-situ ultralow temperature Mossbauer spectroscopy(T=1.6 K)that could essentially differentiate various Fe-N_(4)states and invisible Fe-O *** quantifying with CO-pulse chemisorption,site density and turnover frequency of Fe-N-C catalysts reach 2.4×10^(-9)site g^(-1)and 23 e site~(-1)s^(-1)during the ORR,***-wave potential(0.915V_(RHE))of the Fe-N-C catalyst is more positive(approximately 54 mV)than that of Pt/***,we observe that the performance of PEMFCs on Fe-N-C almost achieves the 2025 target of the US Department of Energy by demonstrating a current density of 1.037 A cm^(-2)combined with the peak power density of 0,685 W cm^(-2),suggesting the critical role of Fe(Ⅱ)-N_(4)site(D1).After 500 h of running,PEMFCs still deliver a power density of 1.26 W cm^(-2)at 1.0 bar H_(2)-O_(2),An unexpected rate-determining step is figured out by isotopic labelling experiment and theoretical *** work not only offers valuable insights regarding the intrinsic contribution of Fe-N_(4)with a single spin state to alkaline/acidic ORR,but also provides great opportunities for developing high-performance stable PEMFCs.

关键词： Fuel cells Oxygen reduction reaction Non-platinum group metals(PGMs) Isotopic labelling Active site TOF

A Novel Design of a Pre-separation Panel Structure to Protect Against the Impact of an Explosion in an Aircraft Plenum Chamber

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Acta Mechanica Solida Sinica 2024年第1期37卷 166-180页

作者： Zongxing liu Xiang Yang Jun liu School of Aeronautics Northwestern Polytechnical UniversityXi'an 710072China COMAC Shanghai Aircraft Design and Research Institute Shanghai 201210China

To reduce the damage of the pressurizing panel structure of a fuselage caused by an explosion at the“least risk bomb location”in an aircraft structure,a new pre-separation panel structure was designed to resist blast ***,the dynamic strain response and morphology of impact damage of the new pre-separation panel were measured in an impact damage ***,the commercial software LS-DYNA was used to calculate the propagation of the blast shock wave,and the results were compared with empirical equations to verify the rationality of the numerical calculation ***,the fluid–structure coupling method was used to calculate the damage process of the pre-separation panel structure under the impact of an explosion wave and an impact *** calculated results were in good agreement with the test results,which showed the rationality of the calculation method and the *** residual strength of the damaged pre-separation panel was significantly higher than that of the original damaged *** results show that the new pre-separation panel structure is reasonable and has certain significance for guiding the design of plenum chambers with strong resistance to implosion for aircraft fuselages.

关键词： Pre-separation panel structure Explosive response Residual strength Aircraft plenum chamber Least risk bomb location