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A novel flexible nerve guidance conduit promotes nerve regeneration while providing excellent mechanical properties

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Neural Regeneration Research 2025年第7期20卷 2084-2094页

作者： Tong Li Quhan Cheng Jingai Zhang Boxin Liu Yu Shi Haoxue Wang Lijie Huang Su Zhang Ruixin Zhang Song Wang Guangxu lu Peifu Tang Zhongyang Liu Kai Wang Department of Orthopedics the Fourth Medical Center of Chinese PLA General HospitalBeijingChina Department of Training and Sports Medicine Characteristic Medical Center of Chinese People’s Armed Police ForceTianjinChina Medical School of Chinese PLA BeijingChina Key Laboratory of Bioactive Materials for the Ministry of Education College of Life SciencesNankai UniversityTianjinChina Department of Orthopedics Tianjin HospitalTianjinChina Department of Rehabilitation Medicine Er Quan Hospital of PAPWuxiJiangsu ProvinceChina

Autografting is the gold standard for surgical repair of nerve defects>5 mm in length;however,autografting is associated with potential complications at the nerve donor *** an alternative,nerve guidance conduits may be *** ideal conduit should be flexible,resistant to kinks and lumen collapse,and provide physical cues to guide nerve *** designed a novel flexible conduit using electrospinning technology to create fibers on the innermost surface of the nerve guidance conduit and employed melt spinning to align ***,we prepared disordered electrospun fibers outside the aligned fibers and helical melt-spun fibers on the outer wall of the electrospun fiber *** presence of aligned fibers on the inner surface can promote the extension of nerve cells along the *** helical melt-spun fibers on the outer surface can enhance resistance to kinking and compression and provide *** novel conduit promoted nerve regeneration and functional recovery in a rat sciatic nerve defect model,suggesting that it has potential for clinical use in human nerve injuries.

关键词： aligned fibers anti-kinking helical fibers nerve guidance conduit nerve regeneration peripheral nerve injury topological guidance

Role of nutrition in diabetes mellitus and infections

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World Journal of Clinical Cases 2025年第3期13卷 1-8页

作者： Xue-lu Yu Li-Yun Zhou Xiao Huang Xin-Yue Li Ming-Ke Wang Ji-Shun Yang Naval Medical Center of PLA Naval Medical UniversityShanghai 200052China

In this editorial,we have commented on the article that has been published in the recent issue of World Journal of Clinical *** authors have described a case of unilateral thyroid cyst and have opined that the acute onset of infection may be linked to diabetes mellitus(DM).We have focused on the role of nutrition in the association between DM and *** with DM are at a high risk of infection,which could also be attributed to nutrition-related *** interventions for patients with diabetes are mainly based on a low-calorie diet,which can be achieved by adhering to a low-carbohydrate ***,dietary fiber supplementation is recommended to maintain the diversity of the gut ***,high-quality protein can prevent the increased risk of infection due to *** of vitamins C,vitamins A,vitamins D,and folic acid improves blood sugar control and facilitates immune *** deficiencies augment the risk of infection,but the relationship with diabetes is mostly U-shaped and a good intake should be maintained.

关键词： Diabetes mellitus Infection Macronutrients Vitamins Minerals

Based on non-targeted metabolomics for differential components screening of Rosae Chinensis Flos and Rosae Rugosae Flos and their quality evaluation

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Traditional Medicine Research 2025年第2期10卷 1-15页

作者： Xu Liang Ni-Hui Zhang Zhi-Lai Zhan Guang-lu Chang Yan Gao Xia Li Wen-Yuan Gao School of Pharmaceutical Science and Technology Faculty of MedicineTianjin UniversityTianjin 300193China State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs China Academy of Chinese Medical SciencesBeijing 100700China Key Laboratory of Modern Chinese Medicine Resources Research Enterprises Tianjin 300402China

Background:Rosa chinensis *** Rosa rugosa *** not only of ornamental value,but also edible flowers and the flower buds have been listed in the Chinese Pharmacopoeia as traditional *** two plants have some differences in efficacy,but the flower buds are easily confused for similar *** addition,large-scale cultivation of ornamental rose flowers may lead to a decrease in the effective components of medicinal ***,it is necessary to study the chemical composition and make quality evaluation of Rosae Chinensis Flos(Yueji)and Rosae Rugosae Flos(Meigui).Methods:In this study,40 batches of samples including Meigui and Yueji from different regions in China were collected to establish high-performance liquid chromatography ***,the fingerprints data was analyzed using principal component analysis,hierarchical cluster analysis,and partial least squares discriminant analysis analysis chemometrics to obtain information on intergroup differences,and non-targeted metabolomic techniques were applied to identify and compare chemical compositions of samples which were chosen from groups with large *** compounds were screened by orthogonal partial least-squares discriminant analysis and S-plot,and finally multi-component quantification was performed to comprehensively evaluate the quality of Yueji and ***:The similarity between the fingerprints of 40 batches roses and the reference print R was 0.73 to 0.93,indicating that there were similarities and differences between the *** principal component analysis and hierarchical cluster analysis of fingerprints data,the samples from different origins and varieties were intuitively divided into four *** least-squares discriminant analysis analysis showed that Meigui and Yueji cluster into two categories and the model was reliable.A total of 89 compounds were identified by high resolution mass spectrometry,mainly were flavonoids and flavon

关键词： Rosa chinensis Jacq. Rosa rugosa Thunb. metabolomics chemometrics multiple component quantification quality evaluation

社会福利水平与资源消耗耦合协调的时空演化及驱动因素

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生态经济 2025年第1期41卷 185-194页

作者：王璐方行明成都大学马克思主义学院四川成都610100 西南财经大学中国西部经济研究院四川成都611100

基于2004—2020年中国省级面板数据,通过构建耦合协调度模型测算社会福利水平与资源消耗之间的协调程度。然后,构建空间杜宾模型实证检验两者耦合协调发展的驱动机制并对各驱动因素的空间效应进行分解。研究结果显示:(1)研究期间内,中... 详细信息

基于2004—2020年中国省级面板数据,通过构建耦合协调度模型测算社会福利水平与资源消耗之间的协调程度。然后,构建空间杜宾模型实证检验两者耦合协调发展的驱动机制并对各驱动因素的空间效应进行分解。研究结果显示:(1)研究期间内,中国社会福利水平与资源消耗之间的耦合协调度整体呈上升趋势,仅个别年份存在回落现象;西部地区耦合协调度低于东、中部地区,而中部地区后来居上,于2017年反超东部地区;上海、北京耦合协调度一直处于领先水平,天津2015年后耦合协调度递减明显。(2)经济规模、产业结构、技术进步、能源消费结构、能源强度、外商投资以及政府规模显著驱动社会福利水平与资源消耗耦合协调发展。(3)社会福利水平与资源消耗耦合协调发展的过程中对周边地区存在正向空间溢出效应,各驱动因素对耦合协调度的影响也存在空间溢出效应。其中,产业结构、技术进步与能源消费结构的直接效应与间接效应方向相反。

关键词：社会福利水平资源消耗耦合协调度驱动因素空间效应分解

2022年泸定6.8级地震房屋震害及其统计分析

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地震研究 2025年第1期48卷 123-131页

作者：孙路刘金龙湖州职业技术学院建筑工程学院浙江湖州313000 湖州市绿色建筑技术重点实验室浙江湖州313000 中国地震局工程力学研究所中国地震局地震工程与工程振动重点实验室黑龙江哈尔滨150080

2022年四川省甘孜州泸定县发生6.8级地震。依据现场调查资料,介绍了震区房屋的主要结构类型及其建造特点,总结了各类房屋结构的典型震害现象,探讨了各类房屋典型震害特征的产生机理。通过震害数据的统计分析,建立了本次地震中各类结构... 详细信息

2022年四川省甘孜州泸定县发生6.8级地震。依据现场调查资料,介绍了震区房屋的主要结构类型及其建造特点,总结了各类房屋结构的典型震害现象,探讨了各类房屋典型震害特征的产生机理。通过震害数据的统计分析,建立了本次地震中各类结构房屋的震害矩阵,并与其他学者的研究成果进行了对比,研究了不同房屋类型各地震破坏等级分布规律,给出了砖混结构房屋的地震易损性曲线。根据本次地震的震害特点,给出了提升房屋抗震能力的建议。

关键词：泸定6.8级地震房屋震害抗震能力

数字赋能乡村公共文化事业高质量发展——以乡村图书馆建设为例

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三峡大学学报（人文社会科学版） 2025年第1期47卷 65-71页

作者：卢迪曲阜师范大学马克思主义学院山东济宁273100

数字赋能乡村公共文化事业高质量发展是全面推进乡村振兴战略的基本要求,也是逐步实现人民群众精神文化生活共同富裕的题中之义。乡村图书馆是乡村公共文化服务体系的重要组成部分,在数字赋能过程中要以民需导向的服务理念、技术支撑的... 详细信息

数字赋能乡村公共文化事业高质量发展是全面推进乡村振兴战略的基本要求,也是逐步实现人民群众精神文化生活共同富裕的题中之义。乡村图书馆是乡村公共文化服务体系的重要组成部分,在数字赋能过程中要以民需导向的服务理念、技术支撑的转型升级、人文铸魂的角色定位、数字乡村的建设助力作为建设的数智图景,同时在基础设施、智慧人才、数字素养、长效机制等方面存在着发展的现实梗阻。因此,在数字赋能乡村图书馆建设过程中要从推进数字化基础设施建设、加强智慧人才的人力储备、全方位提升乡村数字素养、优化数字转型的顶层设计这四个方面入手。

关键词：数字赋能乡村公共文化乡村图书馆

Lipomatous ependymoma with ZFTA:RELA fusion-positive:A case report

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World Journal of Clinical Cases 2025年第1期13卷 48-55页

作者： Xiao-Yu Zhao Juan-Han Yu Yi-Hua Wang Yi-Xin Liu lu Xu Lin Fu Ning Yi China Medical University The First Hospital of China Medical UniversityShenyang 110001Liaoning ProvinceChina Department of Pathology The First Hospital of China Medical UniversityShenyang 110001Liaoning ProvinceChina Anshan Cancer Hospital Anshan 114000Liaoning ProvinceChina

BACKGROUND Ependymoma with lipomatous differentiation is a rare type of *** ZFTA fusion-positive supratentorial ependymoma is a novel tumor type in the 2021 World Health Organization classification of central nervous system *** fusion-positive lipomatous ependymoma has not been reported to *** SUMMARY We reported a case of a 15-year-old Chinese male who had a sudden convulsion lasting approximately six *** resonance imaging showed a round cystic shadow of approximately 1.9 cm×1.5 cm×1.9 cm under the right parieto-occipital *** examination showed characteristic perivascular pseudorosettes and adipose differentiation in the ***-chemical staining showed that the tumor cells were negative for cytokeratin,NeuN,Syn and p53,but positive for GFAP,vimentin and S-100 ***-ficant punctate intracytoplasmic EMA immunoreactivity was *** level of Ki-67 was about 5%.Genetic analysis revealed ZFTA:RELA fusion.A cranio-tomy with total excision of the tumor was *** follow-up time was 36 months,no evidence of disease recurrence was found in magnetic resonance *** Based on these findings,the patient was diagnosed as a ependymoma with ZFTA fusion and lipomatous *** case report provides information on the microscopic morphological features of ependymoma with ZFTA fusion and lipomatous differentiation,which can help pathologists to make a definitive diagnosis of this tumor.

关键词： Ependymoma Lipomatous Molecular classification Supratentorial ZFTA:RELA fusion Case report

Spatiotemporal characteristics and influencing factors of vegetation water use efficiency on the Tibetan Plateau in 2001–2020

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Journal of Geographical Sciences 2025年第1期 39-64页

作者： HE Chenyang WANG Yanjiao YAN Feng lu Qi School of Ecological and Environmental Science East China Normal University Institute of Ecological Conservation and Restoration Chinese Academy of Forestry National Climate Center China Meteorological Administration

Water use efficiency （WUE）,as a pivotal indicator of the coupling degree within the carbon–water cycle of ecosystems,holds considerable importance in assessment of the carbon–water balance within terrestrial ***,in the context of global warming,WUE evolution and its primary drivers on the Tibetan Plateau remain *** study employed the ensemble empirical mode decomposition method and the random forest algorithm to decipher the nonlinear trends and drivers of WUE on the Tibetan Plateau in 2001–*** indicated an annual mean WUE of 0.8088 gC/mm·m2across the plateau,with a spatial gradient reflecting decrease from the southeast toward the *** manifesting monotonous trends of increase or decrease in WUE accounted for 23.64%and 9.69%of the total,***,66.67%of the region exhibited trend reversals,i.e.,39.94%of the area of the Tibetan Plateau showed transition from a trend of increase to a trend of decrease,and 26.73%of the area demonstrated a shift from a trend of decrease to a trend of *** factors accounted for 70.79%of the variability in *** leaf area index and temperature served as the major driving forces of WUE variation.

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基于耦合界面键合效应的石墨烯磨损研究

原子与分子物理学报 2025年第6期42卷 66-75页

作者：郑云飞卢艳武汉科技大学冶金装备及其控制教育部重点实验室武汉430081 武汉科技大学机械传动与制造工程湖北省重点实验室武汉430081 武汉科技大学精密制造研究院武汉430081

石墨烯作为二维固体润滑材料,其超滑特性不仅是物理作用结果,其化学键结构机制下的摩擦化学现象,是深入理解石墨烯摩擦性能的关键.本文采用分子动力学(MD)方法构建了多重层数石墨烯增强不同粗糙形貌的金属基底模型,实现了其与金刚石尖... 详细信息

石墨烯作为二维固体润滑材料,其超滑特性不仅是物理作用结果,其化学键结构机制下的摩擦化学现象,是深入理解石墨烯摩擦性能的关键.本文采用分子动力学(MD)方法构建了多重层数石墨烯增强不同粗糙形貌的金属基底模型,实现了其与金刚石尖端滑动过程的动态分析,揭示了考虑尖端与石墨烯之间存在界面键时石墨烯层的理化耦合作用下的磨损机理.研究结果表明:当考虑金刚石尖端与石墨烯之间化学键合时,石墨烯发生磨损破裂的临界载荷相对于不考虑界面化学键时的值减小,这是由于界面键的形成会剥离石墨烯导致石墨烯断裂所致;金属基底的粗糙度也是决定石墨烯发生磨损破裂时临界载荷的重要因素之一,当粗糙度增大,临界载荷减小,同时通过增加石墨烯层的层数(增韧)来提高石墨烯发生磨损破裂失效的临界载荷.

关键词：石墨烯层界面键分子动力学磨损破裂

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