检索结果-南通市图书馆

Two-photon polymerization-based 4D printing and its applications

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Extreme Manufacturing 2024年第1期6卷 1-25页

作者： bingcong Jian Honggeng li Xiangnan He rong Wang Hui Ying Yang Qi Ge Shenzhen Key Laboratory of Soft Mechanics&Smart Manufacturing Southern University of Science and TechnologyShenzhen 518055People’s Republic of China Department of Mechanical and Energy Engineering Southern University of Science and TechnologyShenzhen 518055People’s Republic of China Pillar of Engineering Product Development Singapore University of Technology and Design8 Somapah RoadSingapore 487372Singapore

Two-photon polymerization(TPP)is a cutting-edge micro/nanoscale three-dimensional(3D)printing technology based on the principle of two-photon absorption.TPP surpasses the diffraction limit in achieving feature sizes and excels in fabricating intricate 3D micro/nanostructures with exceptional resolution.The concept of 4D entails the fabrication of structures utilizing smart materials capable of undergoing shape,property,or functional changes in response to external stimuli over time.The integration of TPP and 4D printing introduces the possibility of producing responsive structures with micro/nanoscale accuracy,thereby enhancing the capabilities and potential applications of both technologies.This paper comprehensively reviews TPP-based 4D printing technology and its diverse applications.First,the working principles of TPP and its recent advancements are introduced.Second,the optional4D printing materials suitable for fabrication with TPP are discussed.Finally,this review paper highlights several noteworthy applications of TPP-based 4D printing,including domains such as biomedical microrobots,bioinspired microactuators,autonomous mobile microrobots,transformable devices and robots,as well as anti-counterfeiting microdevices.In conclusion,this paper provides valuable insights into the current status and future prospects of TPP-based4D printing technology,thereby serving as a guide for researchers and practitioners.

关键词： two-photonpolymerization 4D printing nano/micro fabrication microrobot

Gastric microbiota transplantation as a potential treatment for immune checkpoint inhibitor-associated gastritis

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2024年第24期30卷 3123-3125页

作者： Bo-Tong Ma li-Xuan Sang bing Chang Department of Gastroenterology The First Affiliated Hospital of China Medical UniversityShenyang 110001Liaoning ProvinceChina Department of Gastroenterology Shengjing Hospital of China Medical UniversityShenyang 110022Liaoning ProvinceChina

Immune-related adverse events(irAEs)are complications of the use of immune checkpoint inhibitors(ICIs).ICI-associated gastritis is one of the main irAEs.The gastric microbiota is often related to the occurrence and development of many gastric diseases.Gastric microbiota adjustment may be used to treat gastric disorders in the future.Faecal microbiota transplantation can alter the gut microbiota of patients and has been used for treating ICI-associated colitis.Therefore,we propose gastric microbiota transplantation as a supplementary treatment for patients with ICI-associated gastritis who do not respond well to conventional therapy.

关键词： Immune checkpoint inhibitor Immune-related adverse events Gastritis Gastric microbiota transplantation Probiotics

Acute suppurative terminal cholangitis:Clinical characteristics of a new subtype of acute cholangitis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hepatobiliary & Pancreatic Diseases International 2024年第3期23卷 293-299页

作者： rong-Tao Zhu Ye li Chi-Xian Zhang Wei-Jie Wang Ruo-Peng liang Jian li Kai Bai Yu-ling Sun Department of Hepatobiliary and Pancreatic Surgery the First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450052China Zhengzhou Key Laboratory of Hepatobiliary and Pancreatic Diseases Zhengzhou 450052China Institute of Hepatobiliary and Pancreatic Diseases Zhengzhou UniversityZhengzhou 450052China Department of Pathology the First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450052China

Background:Acute suppurative terminal cholangitis(ASTC)is rarer than acute obstructive cholangitis and is not well studied.To explore this subtype of acute cholangitis,we described our clinical experience with ASTC.Methods:We performed a retrospective review of patients with ASTC admitted to our center from September 2014 to August 2020.We analyzed their clinical characteristics,including etiology,clinical manifestations,imaging features,treatment and prognosis.Results:A total of 32 ASTC patients were included in the analysis.The majority of the patients had a history of biliary operations,and clinical manifestations were occult and atypical.The positive rate of bacterial culture was 46.9%.All the patients had typical imaging features on computed tomography and magnetic resonance imaging.Treatment with effective antibiotics was provided as soon as diagnosis was established.After treatment,most patients had a good outcome.Elevated levels of total bilirubin,aspartate aminotransferase,procalcitonin and gamma-glutamyltransferase were the characteristics of critically ill patients and were associated with relatively poor prognosis.Conclusions:Our results demonstrated that ASTC should be recognized as a new subtype of acute cholangitis,and that earlier diagnosis and more personalized treatments are needed.

关键词： Acute suppurative terminal cholangitis Acute cholangitis Gram-negative bacterial infections Diagnosis Treatment

Effects of Bisphenol A and Its Substitute, Bisphenol F, on the Gut Microbiota in Mice

在线全文

学校读者我要写书评

暂无评论

Biomedical and Environmental Sciences 2024年第1期37卷 19-30页

作者： MENG li Ying TAO Wen Fu li Jing ZHU Min ZHONG De Bin ZHOU Jing QIN Xue WEI rong Guo Department of Clinical Laboratory The First Affiliated Hospital of Guangxi Medical UniversityNanning 530021GuangxiChina Department of Clinical Laboratory The Fifth Affiliated Hospital of Guangxi Medical UniversityNanning 530021GuangxiChina Jiangsu Key Laboratory of Environmental Engineering Jiangsu Academy of Environmental SciencesNanjing 210000JiangsuChina

Objective The aim of this study was to assess the impact of bisphenol A(BPA)and its substitute,bisphenol F(BPF),on the colonic fecal community structure and function of mice.Methods We exposed 6–8-week-old male C57BL/6 mice to 5 mg/(kg∙day)and 50μg/(kg∙day)of BPA or BPF for 14 days.Fecal samples from the colon were analyzed using 16S rRNA sequencing.Results Gut microbiome community richness and diversity,species composition,and function were significantly altered in mice exposed to BPA or BPF.This change was characterized by elevated levels of Ruminococcaceae UCG-010 and Oscillibacter and decreased levels of Prevotella 9 and Streptococcus.Additionally,pathways related to carbohydrate and amino acid metabolism showed substantial enrichment.Conclusion Mice exposed to different BP analogs exhibited distinct gut bacterial community richness,composition,and related metabolic pathways.Considering the essential role of gut bacteria in maintaining intestinal homeostasis,our study highlights the intestinal toxicity of BPs in vertebrates.

关键词： Bisphenol A(BPA) Bisphenol F(BPF) 16S rRNA Microbiota

Upadacitinib for refractory ulcerative colitis with primary nonresponse to infliximab and vedolizumab:A case report

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2024年第9期12卷 1685-1690页

作者： Xuan Xu Jing-Wen Jiang bing-Yun Lu Xia-Xi li Department of Gastroenterology Shenzhen HospitalSouthern Medical UniversityShenzhen 518100Guangdong ProvinceChina The First Clinical Medical School Southern Medical UniversityGuangzhou 510515Guangdong ProvinceChina

BACKGROUND Many patients with ulcerative colitis(UC)do not respond well to,or tolerate conventional and biological therapies.There is currently no consensus on the treatment of refractory UC.Studies have demonstrated that the selective Janus kinase 1 inhibitor upadacitinib,a small-molecule drug,is effective and safe for treating UC.However,no studies have revealed that upadacitinib is effective in treating refractory UC with primary nonresponse to infliximab and vedolizumab.CASE SUMMARY We report the case of a 44-year-old male patient with a chief complaint of bloody diarrhoea with mucus and pus,in addition to dizziness.The patient had recurrent disease after receiving mesalazine,prednisone,azathioprine,infliximab and vedolizumab over four years.Based on the endoscopic findings and pathological biopsy,the patient was diagnosed with refractory UC.In particular,the patient showed primary nonresponse to infliximab and vedolizumab.Based on the patient’s history and recurrent disease,we decided to administer upadacitinib.During hospitalisation,the patient was received upadacitinib under our guidance.Eight weeks after the initiation of upadacitinib treatment,the patient’s symptoms and endoscopic findings improved significantly.No notable adverse reactions have been reported to date.CONCLUSION Our case report suggests that upadacitinib may represent a valuable strategy for treating refractory UC with primary nonresponse.

关键词： Upadacitinib Refractory ulcerative colitis Primary nonresponse Infliximab Vedolizumab Case report

Perioperative nutrition optimization:a review of the current literature

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of Nursing 2024年第2期11卷 127-137页

作者： Jin-Shuai li Wei-bing Shuang First Clinical Medical College Shanxi Medical UniversityTaiyuanShanxi 030001China Department of Urology The First Hospital of Shanxi Medical UniversityTaiyuanShanxi 030001China

Objective:This article aims to elaborate the recent research status of perioperative nutrition optimization,in order to help clinical practice.Methods:This study employed a comprehensive and systematic method to search prominent databases,including PubMed and Web of Science,using carefully selected keywords.Following meticulous screening,the inclusion of high-quality studies was prioritized,and a thorough review of the references was conducted to comprehensively analyze the latest evidence on perioperative nutrition optimization.Results:The main contents include preoperative nutritional risk screening and assessment,nutritional support pathway,immune enhancing nutrition,preoperative and postoperative nutritional management,as well as personalized nutrition optimization strategies for specific populations(such as children,bariatric surgery patients,and cancer patients).Conclusions:In clinical practice,the importance of perioperative nutrition should be emphasized,and personalized nutrition management plans should be developed based on the characteristics and needs of patients.Further research and promotion of perioperative nutrition optimization strategies will help improve the overall prognosis and quality of life of surgical patients.

关键词： enteral nutrition immune enhancing nutrition nutritional screening and assessment parenteral nutrition perioperative

Polyneuropathy, organomegaly, endocrinopathy, M-protein, skin changes syndrome with dilated cardiomyopathy: A case report

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2024年第3期12卷 601-606页

作者： Jia-rong li Lei-Yu Feng Jian-Wei li Yu liao Fei-Qi liu Department of General Medicine Xiangtan Central HospitalXiangtan 411100Hunan ProvinceChina

BACKGROUND Polyneuropathy,organomegaly,endocrinopathy,M-protein,skin changes(POEMS)syndrome is a rare paraneoplastic syndrome that encompass multiple systems.The most common clinical symptoms of POEMS syndrome are pro-gressive sensorimotor polyneuropathy,organ enlargement,endocrine disorders,darkening skin,a monoclonal plasma cell proliferative disorder,and lymph node hyperplasia.The organomegaly consists of hepatosplenomegaly and/or lym-phadenopathy;cases of cardiomyopathy are rare.Diagnoses are often delayed because of the atypical nature of the syndrome,exposing patients to possibly severe disability.Therefore,identifying atypical symptoms can improve the prognosis and quality of life among POEMS syndrome patients.lenalidomide and dexamethasone.CONCLUSION When patients with cardiomyopathy have systemic manifestations such as numb limbs and darkening skin,the POEMS syndrome is the most possible diagnosis.

关键词： Polyneuropathy organomegaly endocrinopathy M-protein skin changes syndrome Dilated cardiomyopathy Lenalidomide Dexamethasone Case report

Design of weak current measurement system and research on temperature impact

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nuclear Science and Techniques 2024年第4期35卷 46-56页

作者： Chu-Xiang Zhao San-Gang li rong-rong Su li Yang Ming-Zhe liu Qing-Yue Xue Shan liao Zhi Zhou Qing-Shan Tan Xian-Guo Tuo Yi Cheng College of Nuclear Technology and Automation Engineering Chengdu University of Technology1#DongsanluErxianqiaoChengdu 610059China Applied Nuclear Technology in Geosciences Key Laboratory of Sichuan Province Chengdu University of Technology1#DongsanluErxianqiaoChengdu 610059China University of Science and Technology of China Hefei 230026China School of Physics and Electronic Engineering Sichuan University of Science and EngineeringZigong 643000China

A dedicated weak current measurement system was designed to measure the weak currents generated by the neutron ionization chamber.This system incorporates a second-order low-pass filter circuit and the Kalman filtering algorithm to effectively filter out noise and minimize interference in the measurement results.Testing conducted under normal temperature conditions has demonstrated the system's high precision performance.However,it was observed that temperature variations can affect the measurement performance.Data were collected across temperatures ranging from -20 to 70℃,and a temperature correction model was established through linear regression fitting to address this issue.The feasibility of the temperature correction model was confirmed at temperatures of -5 and 40℃,where relative errors remained below 0.1% after applying the temperature correction.The research indicates that the designed measurement system exhibits excellent temperature adaptability and high precision,making it particularly suitable for measuring weak currents.

关键词： Weak current measurement system Neutron ionization chamber Kalman filter algorithm Temperature correction model

Convex-up Style of Deformation within Grabens in Regions of Incomplete Crossing Conjugate Normal Faults: A Numerical Simulation Investigation and Case Study

在线全文

学校读者我要写书评

暂无评论

Journal of Earth Science 2024年第3期35卷 839-849页

作者： Zheng li Kai Wang Xiong Xiong bing Zhou School of Geophysics and Geomatics China University of GeosciencesWuhan 430074China State Key Laboratory of Geodesy and Earth’s Dynamics Innovation Academy for Precision Measurement Science and TechnologyChinese Academy of SciencesWuhan 430077China Department of Earth Sicences Khalifa UniversityAbu DhabiUnited Arab Emirates

Crossing conjugate normal faults(CCNFs)are extensively developed in many hydrocarbon-producing basins,generally existing in the form of incomplete CCNFs.Nevertheless,the effect of the non-conjugate zone of the CCNFs on the conjugate relay zone post late tectonic action has not been previously studied.We use 3D elastic-plastic modeling to investigate the influence of incomplete(i.e.,partially intersecting)CCNFs on the pattern of deformation of strata in the intersection region.A series of model simulations were performed to examine the effects of horizontal tectonic extension,fault size,and fault depth on the deformation of conjugate relay zones of incomplete CCNFs.Our analyses yielded the following results.(1)The model of incomplete conjugation predicts a convex-up style of deformation in the conjugate graben region superimposed on overall subsidence under applied horizontal tectonic extension.(2)The degree of convex-up deformation of the conjugate graben depends on the influence of the non-conjugate zone on the conjugate relay zone,which varies with the amount of horizontal tectonic extension,fault size,and fault burial depth.(3)Our results indicate that incomplete CCNFs can form convex-up deformation,similar to that in the Nanpu Sag area and provide a sound understanding of hydrocarbon migration and accumulation.

关键词： incomplete conjugate normal fault conjugate graben convex-up deformation hydrocarbons Nanpu Sag tectonics.