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First case of forearm crisscross injury in children:A case report

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World Journal of Clinical Cases 2021年第25期9卷 7478-7483页

作者： Yi-Kun Jiang yan-bing wang Chuan-Gang Peng Ji Qu Dan-Kai Wu Department of Orthopedics The Second Hospital of Jilin UniversityChangchun 130000Jilin ProvinceChina

BACKGROUND Forearm crisscross injury is rare in children;there is no relevant literature so *** lack experience and knowledge in treating this type of crisscross *** report a case of forearm crisscross injury in a child for the first time and analyze its *** SUMMARY An 8-year-old boy experienced pain in his left forearm when he accidentally fell while *** examination revealed swelling and deformity of the left *** performed imaging and the results revealed left radial head dislocation,left distal radial epiphyseal separation from the shaft,and interruption of the continuity of the dorsal cortex of the left distal *** and lateral X-ray films showed that the radius and ulna were crisscrossed.A diagnosis of superior radioulnar joint dislocation,left distal radial epiphyseal injury,and left distal ulnar fracture was *** unsuccessful manual reduction,we adopted a minimally invasive procedure and *** a 14-wk period of follow-up,the patient had good left upper limb function,no complaints of pain or limited range of motion,and good follow-up *** This is the first report of a child with a forearm crisscross injury in which the mechanism and the differences from adult crisscross injury are *** invasive surgery with intramedullary fixation can achieve a good therapeutic *** case provides a reference for the treatment of similar patients in the future.

关键词： Children Forearm Cross injury Fracture Case report

Anti-tumor effects of combined doxorubicin and siRNA for pulmonary delivery

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Chinese Chemical Letters 2017年第4期28卷 807-812页

作者： Cai-Na Xu Hua-Yu Tian yan-bing wang yang Du Jie Chen Lin Lin Zhao-Pei Guo Xue-Si Chen Key Laboratory of Polymer Ecomaterials Changchun Institute of Applied Chemistry Chinese Academy of Sdences Changchun 130022 China

Direct administration of drugs and genes to the lungs by pulmonary delivery offers a potential effective therapy for lung *** this study,combined doxorubicin（DOX） and Bcl2 siRNA was employed for cancer therapy using polyethylenimine（PEI） as the carrier of Bcl2 *** of the DOX and siRNA possessed high cellular uptake efficiency in B16F10 cells,which was proved by FCM and CLSM ***-time PCR showed that PEI/Bcl2 siRNA exhibited high gene silencing efficiency with 70%Bcl2 mRNA being knocked *** combination of DOX and siRNA could enhance the cell proliferation inhibition and the cell apoptosis against B16F10 cells compared to free DOX or PEI/Bcl2 ***,the biodistribution of DOX and siRNA via pulmonary administration was studied in mice with B16F10 metastatic lung *** results showed that most of the DOX and siRNA were accumulated in lungs and lasted at least for 3 days,which suggested that combined DOX and siRNA by pulmonary administration may have high anti-tumor effects for metastatic lung cancer treatment in vivo.

关键词： Pulmonary delivery Anti-tumor effects Metastatic lung cancer Combined DOX and siRNA therapy Synergistic anti-tumor

Features of gastric cancer by anatomic subsite in northern China: A multi-center Health Science Report database study

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World Journal of Gastrointestinal Oncology 2022年第11期14卷 2238-2252页

作者： Rui-Ze Qu yan-Peng Ma Xiao-Yuan Bao Li-Yuan Tao Xin Zhou Si-Yi Lu Yi Zhang bing-yan wang Fei Li Lin Tuo Zhi-Peng Zhang Wei Fu Department of General Surgery Cancer CenterPeking University Third HospitalBeijing 100191China Medical Informatics Center Peking University Health Science CenterBeijing 100191China Research Center of Clinical Epidemiology Peking University Third HospitalBeijing 100191China Department of Hospital Management Peking University Health Science CenterBeijing 100191China

BACKGROUND The features of gastric cancer based on the anatomic site remain unknown in northern China *** To analyze gastric cancer features and associated trends based on the anatomical site in northern China *** This cross-sectional study used incident gastric cancer case data from 10 Peking University-affiliated hospitals(2014 to 2018).The clinical and prevailing local features were *** A total of 10709 patients were enrolled,including antral(42.97%),cardia(34.30%),and stomach body(18.41%)gastric cancer *** in the cardia had the highest male:female ratio,proportion of elderly patients,and patients with complications,including hypertension,diabetes,cerebrovascular,and coronary diseases(P<0.001).gastric cancer involving the antrum showed the lowest proportion of patients from rural areas and accounted for the highest hospitalization rate and cost(each P<0.001).The proportion of patients with cancer involving the cardia increased with an increase in the number of gastroesophageal reflux disease cases during the same period(P<0.001).Multivariate analysis revealed that tumor location in the cardia increased the risk of inhospital mortality(P=0.046).Anatomical subsite was not linked to postoperative *** The features of gastric cancer based on the anatomical site differ between northern China and other regions,both globally and within the *** factors may account for these differences and should affect policy-making and clinical practice.

关键词： Feature Gastric cancer Anatomical site Northern China

Network analysis identifies common genes associated with obesity in six obesity-related alseases

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2017年第8期18卷 727-732页

作者： Li-ning SU yan-bing wang Chun-guang WNAG Hui-ping WEI Department of Biology Hebei North University Zhangjiakou 075029China Department of Public Sports Hebei North University Zhangjiakou075029 China Department of Cardiac Function Examination the First AffiliatedHospital Hebei North University Zhangjiakou 075061 China

Obesity has been reported to be associated withmany diseases. However, common obesity-inducedbiological processes have not been evaluated acrossthese diseases. We identified genes associated withobesity and obesity-related diseases, and used them toconstruct protein-protein interaction networks. We alsoanalyzed gene ontology （GO） in those genes over-lapping between obesity and disease. Our work iden-tifies gene modules common to obesity and obesity-related diseases, which can provide a basis for under-standing the process of how obesity induces disease.

关键词：浙江大学学报英文版

Successful thrombolytic therapy following emergent pulmonary embolectomy: a case report

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中华医学杂志(英文版) 2005年第17期 84-86页

作者： XU Chang-xian, wang Zi-bing, ZHANG yan-an, wang Xu-jian, XIN Hong-yan, HUO Yu-feng, LI Jian and yanG Chuan-binDepartment of Cardiovascular Surgery, Second Hospital of Shandong University, Jinan 250033, ChinaDepartment of Cardiovascular Surgery, Shandong Chest Hospital,Jinan 250013, China

Silk damping in scalar-induced gravitational waves: a novel probe for new physics

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 79-85页

作者： yan-Heng Yu Sai wang Theoretical Physics Division Institute of High Energy Physics Chinese Academy of Sciences School of Physics University of Chinese Academy of Sciences

Silk damping is well known in the study of cosmic microwave background（CMB） and accounts for suppression of the angular power spectrum of CMB on large angular multipoles. In this article, we study the effect of Silk damping on the scalar-induced gravitational waves（SIGWs）. Resulting from the dissipation of cosmic fluid, the Silk damping notably suppresses the energydensity spectrum of SIGWs on scales comparable to a diffusion scale at the decoupling time of weakly-interacting particles. The effect offers a novel observable for probing the underlying particle interaction, especially for those mediated by heavy gauge bosons beyond the standard model of particles. We anticipate that pulsar timing arrays are sensitive to gauge bosons with mass ～10～3-10～4 GeV, while space-and ground-based interferometers to those with mass ～10～7-1012GeV, leading to essential complements to on-going and future experiments of high-energy physics.

关键词： scalar-induced gravitational waves Silk damping new physics

High-energy-density lithium manganese iron phosphate for lithium-ion batteries: Progresses, challenges, and prospects

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Journal of Energy Chemistry 2025年第1期100卷 1-17页

作者： Bokun Zhang Xiaoyun wang Shuai wang yan Li Libo Chen Handong Jiao Zhijing Yu Jiguo Tu State Key Laboratory of Advanced Metallurgy University of Science and Technology Beijing Research Institute for Intelligent Wearable Systems The Hong Kong Polytechnic University Institute of Advanced Structure Technology Beijing Institute of Technology

The soaring demand for smart portable electronics and electric vehicles is propelling the advancements in high-energy–density lithium-ion *** manganese iron phosphate (LiMnxFe1-xPO4) has garnered significant attention as a promising positive electrode material for lithium-ion batteries due to its advantages of low cost,high safety,long cycle life,high voltage,good high-temperature performance,and high energy *** LiMnxFe1-xPO4has made significant breakthroughs in the past few decades,there are still facing great challenges in poor electronic conductivity and Li-ion diffusion,manganese dissolution affecting battery cycling performance,as well as low tap *** review systematically summarizes the reaction mechanisms,various synthesis methods,and electrochemical properties of LiMnxFe1-xPO4to analyze reaction processes accurately and guide material ***,the main challenges currently faced are concluded,and the corresponding various modification strategies are discussed to enhance the reaction kinetics and electrochemical performance of LiMnxFe1-xPO4,including multi-scale particle regulation,heteroatom doping,surface coating,as well as microscopic morphology ***,in view of the current research challenges faced by intrinsic reaction processes,kinetics,and energy storage applications,the promising research directions are *** importantly,it is expected to provide key insights into the development of high-performance and stable LiMnxFe1-xPO4materials,to achieve practical energy storage requirements.

关键词： Lithium manganese iron phosphate High energy density Lithium-ion batteries Reaction mechanism Tap density

钛网结合异体骨移植和人骨形成蛋白在上颌前牙种植前牙槽嵴骨增量中的应用研究(附1例报告)

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中国实用口腔科杂志 2014年第1期7卷 24-27页

作者： bing-yan wang Robin Weltman Jared Abramian 李琛潘亚萍美国德克萨斯健康研究中心牙学院美国德克萨斯州休斯敦77054 中国医科大学附属口腔医院牙周科辽宁省口腔医学研究所沈阳110002

萎缩的牙槽嵴对于种植牙而言是一个不利的因素,在植入种植体之前牙槽骨嵴增量手术能够使骨的体积增加。在上颌前牙区,牙槽嵴增量不仅有利于后期种植体的植入而且可以获得更好美学效果。本文详述用钛网结合异体骨移植和人骨形成蛋白治疗... 详细信息

萎缩的牙槽嵴对于种植牙而言是一个不利的因素,在植入种植体之前牙槽骨嵴增量手术能够使骨的体积增加。在上颌前牙区,牙槽嵴增量不仅有利于后期种植体的植入而且可以获得更好美学效果。本文详述用钛网结合异体骨移植和人骨形成蛋白治疗上前牙区部分牙缺失部位的颊舌向骨缺损。通过这种方法可获得一定的骨增量,8个月后植入种植体,在植入种植体后4个月行二期手术和临时修复,4个月后进行永久修复,追踪时间为2年。

关键词：牙槽嵴增量钛网骨形成蛋白骨移植种植

A Novel Model for Describing Rail Weld Irregularities and Predicting Wheel-Rail Forces Using a Machine Learning Approach

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Computer Modeling in Engineering & Sciences 2025年第1期142卷 555-577页

作者： Linlin Sun Zihui wang Shukun Cui Ziquan yan Weiping Hu Qingchun Meng State Key Laboratory of High-Speed Railway Track System China Academy of Railway Sciences Corporation LimitedBeijing100081China Railway Engineering Research Institute China Academy of Railway Sciences Corporation LimitedBeijing100081China School of Aeronautic Science and Engineering Beihang UniversityBeijing100191China

Rail weld irregularities are one of the primary excitation sources for vehicle-track interaction dynamics in modern high-speed *** can cause significant wheel-rail dynamic interactions,leading to wheel-rail noise,component damage,and *** researchers have employed the vehicle-track interaction dynamic model to study the dynamic interactions between wheel and rail induced by rail weld geometry ***,the cosine wave model used to simulate rail weld irregularities mainly focuses on the maximum value and neglects the geometric *** this study,novel theoretical models were developed for three categories of rail weld irregularities,based on measurements of the high-speed railway from Beijing to *** vertical dynamic forces in the time and frequency domains were compared under different running *** forces generated by the rail weld irregularities that were measured and modeled,respectively,were compared to validate the accuracy of the proposed ***,based on the numerical study,the impact force due to rail weld irrregularity is modeled using an Artificial Neural Network(ANN),and the optimum combination of parameters for this model is *** results showed that the proposed model provided a more accurate wheel/rail dynamic evaluation caused by rail weld irregularities than that established in the *** ANN model used in this paper can effectively predict the impact force due to rail weld irrregularity while reducing the computation time.

关键词： Rail weld irregularity high-speed railway vehicle-track coupled dynamics wheel/rail dynamic vertical force artificial neural networks