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火电厂厂级负荷优化控制系统研制及应用

中国电力 2016年第12期49卷 96-100页

作者：牛洪海李兵陈俊南京南瑞继保电气有限公司江苏南京211102

针对目前电网单机发电控制模式无法兼顾电厂机组安全经济运行的现状,分析了厂级负荷控制系统的发展与应用现状,对其系统架构、负荷优化控制模型等关键技术进行了研究。首先提出了一种基于嵌入式装置、双机冗余的厂级负荷控制系统架构,... 详细信息

针对目前电网单机发电控制模式无法兼顾电厂机组安全经济运行的现状,分析了厂级负荷控制系统的发展与应用现状,对其系统架构、负荷优化控制模型等关键技术进行了研究。首先提出了一种基于嵌入式装置、双机冗余的厂级负荷控制系统架构,在满足电网控制实时性要求的同时实现了电厂信息的高度集成,进而在常规以全厂煤耗量最小为目标的负荷经济分配模型基础上,综合考虑电网调频需要,建立了AGC模式下的火电机组负荷在线优化控制模型。仿真结果表明,可降低全厂发电标煤耗约0.3 g/(k W·h)。最后对厂级负荷优化控制系统的主要功能进行了阐述,可为厂级负荷优化控制系统的改造与实施提供借鉴。

关键词：火电机组自动发电控制厂级负荷控制系统架构控制策略节能

Targeting cholesterol trafficking to mitigate axonal degeneration in hereditary spastic paraplegia

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Neural Regeneration Research 2025年第5期20卷 1397-1398页

作者： Zhenyu chen Xue-jun Li Department of Biomedical Sciences University of Illinois College of Medicine RockfordRockfordILUSA Department of Bioengineering University of Illinois at ChicagoChicagoILUSA

Axonal degeneration underlies many debilitating diseases including hereditary spastic paraplegia(HSP),a genetically and clinically diverse group of disorders characterized by spasticity and weakness of the lower *** is one significant cause of chronic neurodisability due to the lack of effective treatments and a wide range of onset ages from early childhood to 70 years.

关键词： degeneration diseases hereditary

Peripheral blood RNA biomarkers can predict lesion severity in degenerative cervical myelopathy

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Neural Regeneration Research 2025年第6期20卷 1764-1775页

作者： Zhenzhong Zheng Jialin chen Jinghong Xu Bin Jiang Lei Li Yawei Li Yuliang Dai bing Wang Department of Spine Surgery The Second Xiangya Hospital of Central South UniversityChangshaHunan ProvinceChina

Degenerative cervical myelopathy is a common cause of spinal cord injury,with longer symptom duration and higher myelopathy severity indicating a worse *** numerous studies have investigated serological biomarkers for acute spinal cord injury,few studies have explored such biomarkers for diagnosing degenerative cervical *** study involved 30 patients with degenerative cervical myelopathy(51.3±7.3 years old,12 women and 18 men),seven healthy controls(25.7±1.7 years old,one woman and six men),and nine patients with cervical spondylotic radiculopathy(51.9±8.6 years old,three women and six men).Analysis of blood samples from the three groups showed clear differences in transcriptomic *** analysis identified 128 differentially expressed genes that were enriched in patients with neurological *** least absolute shrinkage and selection operator analysis,we constructed a five-gene model(TBCD,TPM2,PNKD,EIF4G2,and AP5Z1)to diagnose degenerative cervical myelopathy with an accuracy of 93.5%.One-gene models(TCAP and SDHA)identified mild and severe degenerative cervical myelopathy with accuracies of 83.3%and 76.7%,*** of two immune cell types(memory B cells and memory-activated CD4^(+)T cells)predicted levels of lesions in degenerative cervical myelopathy with 80%*** results suggest that peripheral blood RNA biomarkers could be used to predict lesion severity in degenerative cervical myelopathy.

关键词： biomarkers candidate genes degenerative cervical myelopathy gene expression analysis immune cell types neurological disabilities peripheral blood RNA profiles spinal cord injury

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数据广播环境下移动实时事务的有效并发控制

计算机科学 2008年第4期35卷 54-59页

作者：李国徽杨兵向军陈辉华中科技大学计算机学院武汉430074

在无线数据广播环境下,从移动客户机到数据库服务器的上行带宽非常有限。传统的并发控制协议不适合这种不对称通讯环境。本文结合乐观并发控制协议和时标排序协议提出一种并发控制协议。只读事务满足弱一致性,包含所有更新事务和一个移... 详细信息

在无线数据广播环境下,从移动客户机到数据库服务器的上行带宽非常有限。传统的并发控制协议不适合这种不对称通讯环境。本文结合乐观并发控制协议和时标排序协议提出一种并发控制协议。只读事务满足弱一致性,包含所有更新事务和一个移动只读事务的可串行化图是非循环的。使用本文提出的并发控制协议,移动只读事务能够自主执行,移动更新事务能够较早地检测到数据冲突。模拟试验显示,我们提出的协议相对其它已经存在的并发控制协议来说,能够更好地满足事务截止期。

关键词：数据广播移动实时事务乐观并发控制可串行化

Effects of Bifidobacterium lactis BLa80 on fecal and mucosal flora and stem cell factor/c-kit signaling pathway in simulated microgravity rats

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World Journal of Gastroenterology 2025年第1期31卷 93-109页

作者： Ping Zhang Ying Zhu Pu chen Tong Zhou Zhe-Yi Han jun Xiao Jian-Feng Ma Wen Ma Peng Zang Ying chen Graduate School Hebei North UniversityZhangjiakou 075000Hebei ProvinceChina Key Laboratory of Aerospace Nutrition and Food Engineering China Astronaut Research and Training CenterBeijing 100094China Department of Gastroenterology The Air Force Medical CenterBeijing 100142China Department of Blood Transfusion Air Force Medical CenterBeijing 100142China

BACKGROUND Simulated microgravity environment can lead to gastrointestinal motility *** pathogenesis of gastrointestinal motility disorders is closely related to the stem cell factor(SCF)/c-kit signaling pathway associated with intestinal flora and Cajal stromal ***,intestinal flora can also affect the regulation of SCF/c-kit signaling pathway,thus affecting the expression of Cajal stromal *** cells are the pacemakers of gastrointestinal *** To investigate the effects of Bifidobacterium lactis(***)BLa80 on the intestinal flora of rats in simulated microgravity and on the gastrointestinal motility-related SCF/c-kit *** The internationally recognized tail suspension animal model was used to simulate the microgravity environment,and 30 rats were randomly divided into control group,tail suspension group and drug administration tail suspension group with 10 rats in each group for a total of 28 *** tail group was given *** BLa80 by intragastric administration,and the other two groups were given water intragastric administration,the concentration of intragastric administration was 0.1 g/mL,and each rat was 1 mL/***&eosin staining was used to observe the histopathological changes in each segment of the intestine of each group,and the expression levels of SCF,c-kit,extracellular signal-regulated kinase(ERK)and p-ERK in the gastric antrum of each group were detected by Western blotting and *** fecal flora and mucosal flora of rats in each group were detected by 16S *** Simulated microgravity resulted in severe exfoliation of villi of duodenum,jejunum and ileum in rats,marked damage,increased space between villi,loose arrangement,shortened columnar epithelium of colon,less folds,narrower mucosal thickness,reduced goblet cell number and crypts,and significant improvement after probiotic *** microgravity reduced the expressions of SCF and c-kit,and increased the express

关键词： Simulated microgravity Rat Intestinal flora Gastrointestinal motility Stem cell factor/c-kit signaling pathway

浙江省杭州市595例无主患者4种感染性血清标志物检测结果分析

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疾病监测 2017年第4期32卷 300-302页

作者：钟春燕陈宝炳陈君陈松杭州市第三人民医院浙江杭州310009

目的了解浙江省杭州市无主患者乙型肝炎病毒(HBV)、丙型肝炎病毒(HCV)、梅毒螺旋体(TP)及人类免疫缺陷病毒(HIV)的感染状况。方法对2015年1-12月杭州市第三人民医院收治的595例无主患者,进行血清HBV表面抗原(HBsAg)、HCV抗体(抗-HCV)、T... 详细信息

目的了解浙江省杭州市无主患者乙型肝炎病毒(HBV)、丙型肝炎病毒(HCV)、梅毒螺旋体(TP)及人类免疫缺陷病毒(HIV)的感染状况。方法对2015年1-12月杭州市第三人民医院收治的595例无主患者,进行血清HBV表面抗原(HBsAg)、HCV抗体(抗-HCV)、TP抗体(抗-TP)检测以及HIV抗体(抗-HIV)筛查及确认试验,并对结果进行统计分析。结果 595例无主患者中,HBsAg阳性63例(10.59%),抗-HCV阳性19例(3.19%),抗-TP阳性29例(4.87%),抗-HIV阳性4例(0.67%),均高于普通住院患者,其中抗-HCV及抗-TP阳性率差异有统计学意义(χ~2=5.765,P=0.016;χ~2=14.053,P=0.001)。不同性别及年龄段无主患者4种血清标志物的阳性率差异均无统计学意义(P>0.05)。结论对无主患者进行HBsAg、抗-HCV、抗-TP及抗-HIV检测对减少医疗纠纷及加强医护人员自我保护意识、降低职业暴露风险具有重要意义。

关键词：无主患者乙型肝炎病毒表面抗原丙型肝炎病毒抗体梅毒抗体人类免疫缺陷病毒抗体

准分子激光角膜表层手术与基质层手术对眼波前像差的比较

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国际眼科杂志 2011年第1期11卷 51-55页

作者：李俏李莹龙琴艾凤荣罗岩陈秉钧丁欣中国医学科学院北京协和医院眼科中国北京市100730

目的:比较分析角膜表层与基质层屈光手术后高阶像差及其变化值。方法:行准分子激光治疗的近视眼患者100例200眼,其中接受LASIK手术50例100眼,接受新型表层手术(ASA)50例100眼。LASIK手术组术前等效球镜度(SE)为-1.25～-9.25(平均-5.75±... 详细信息

目的:比较分析角膜表层与基质层屈光手术后高阶像差及其变化值。方法:行准分子激光治疗的近视眼患者100例200眼,其中接受LASIK手术50例100眼,接受新型表层手术(ASA)50例100眼。LASIK手术组术前等效球镜度(SE)为-1.25～-9.25(平均-5.75±1.74)D,ASA手术组术前SE为-2～-9.25(平均-5.42±1.81)D。术前及术后1,3,6mo检查裸眼视力(UCVA)、最佳矫正视力(BSCVA)、球镜及柱镜度数、SE以及波前像差等。结果:C7,C12,RMS3,RMS4,RMS5,RMS6和RMSh的变化值均和球镜度变化值、SE变化值的绝对值显著正相关。术后1mo,ASA组C7绝对值、RMSh,RMS3和RMS6均显著小于LASIK组;术后3mo时,ASA组C7和C14显著小于LASIK组,LASIK组C12显著小于ASA组;术后6mo时,ASA组仅C14显著优于LASIK组。术后1mo时,ASA组RMS3,RMS5,RMS6和RMSh的变化值均显著小于LASIK组,术后3mo时,ASA组RMS6变化值显著小于LASIK组,术后6mo时,ASA组RMS3,RMS6和RMSh的变化值显著小于LASIK组。结论:高阶像差增大程度与球镜度及SE的变化程度正相关。ASA组术后高阶像差及其增大程度均小于LASIK组,术后6mo时两组差异仍显著。

关键词：近视准分子激光原位角膜磨镶术准分子激光上皮下角膜磨镶术微型角膜刀准分子激光原位角膜磨镶术波前像差

从取消药品加成看如何加强治理医药购销领域商业贿赂

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卫生软科学 2017年第8期31卷 32-33页

作者：马路宁谢文梁兵陈军中山大学附属第一医院广东广州510080

阐述了药品加成政策出台的历史沿革及影响,分析取消药品加成并不能完全切断医药之间利益联系的原因,并提出加强医药购销商业贿赂的治理仍然是今后的工作重点。

关键词：药品加成医药购销商业贿赂

Minimum Time Extrema Estimation for Large-Scale Radio-Frequency Identification Systems

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Journal of Computer Science & Technology 2020年第5期35卷 1099-1114页

作者： Xiao-jun Zhu Li-Jie Xu Xiao-bing Wu bing chen College of Computer Science and Technology Nanjing University of Aeronautics and AstronauticsNanjing 211106China Jiangsu Key Laboratory of Dig Data Security and Intelligent Processing Nanjing University of Posts and TelecommunicationsNanjing 210049China Wireless Research Centre University of CanterburyChristchurch 8041New Zealand

We consider the extrema estimation problem in large-scale radio-frequency identification(RFID)systems,where there are thousands of tags and each tag contains a finite *** objective is to design an extrema estimation protocol with the minimum execution *** the standard binary search protocol wastes much time due to inter-frame overhead,we propose a parameterized protocol and treat the number of slots in a frame as an unknown *** formulate the problem and show how to find the best parameter to minimize the worst-case execution ***,we propose two rules to further reduce the execution *** first is to find and remove redundant *** second is to concatenate a frame from minimum value estimation with a frame from maximum value estimation to reduce the total number of *** show that,in a typical scenario,the proposed protocol reduces execution time by 79%compared with the standard binary search protocol.

关键词： radio-frequency identification(RFID)system maximum value estimation minimum value estimation time efficient protocol