检索结果-南通市图书馆

Clean Energy 2019年第3期3卷 217-221页

作者： Xinxian Jiang Boyan Li binbin song Shuwang Zhang Yang Qiu Ying Zhao Dalong Zhong R&D Department NICE Solar PV Research LtdBeijing 102209China Beijing Engineering Research Center of Nano-Structure Thin-Film Solar Cell Beijing 102209China

In this paper,pure titanium(Ti)thin films deposited by radio frequency sputtering were used as a diffusion barrier layer in a flexible copper indium gallium selenium(CIGS)solar cell on a stainless-steel foil and characterized by X-ray diffraction,scanning electron microscopy and second ion mass spectroscopy measurement methods.The influences of the magnetron sputtering pressure on the surface morphology and preferred crystal orientation of Ti films are discussed.It was found that the Ti film showed a(001)preferred orientation and smooth surface topography at lower deposition pressure,while(002)preferred orientation and relatively rough surface topography at higher deposition pressure.In addition,Ti films made with different process pressures were deposited as the barriers and the second ion mass spectroscopy results indicated that a Ti film with the thickness of 200 nm was able to effectively block Fe and Cr diffusion from the stainless-steel foil into the CIGS absorber across the molybdenum back contact.The Ti barrier significantly improved the conversion efficiency of the CIGS solar cell.

关键词： solar cell thin film flexible CIGS solar cell barrier layer

Clinical Internship Teaching Management During the COVID-19 Epidemic

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Contemporary Educational Research 2023年第10期7卷 19-24页

作者： Hai Zeng binbin song Qingbo Qiao Xue Zhao Rui Ma Dan Zhao Xiuyan Wang Hongqi Hospital Affiliated to Mudanjiang Medical University Mudanjiang 157011Heilongjiang ProvinceChina Mudanjiang Medical University Mudanjiang 157011Heilongjiang ProvinceChina

Against the backdrop of the global COVID-19 pandemic,the teaching and management of clinical medical interns have been facing tremendous challenges.When interns majoring in clinical medicine enter the internship position,they lack self-protection awareness and have limited ability to respond to unexpected public health events.This article explores the cognitive situation,existing problems,and improvement measures of clinical medical interns in the post-epidemic era.Therefore,this article proposes a series of improvement measures,including strengthening epidemic training and education for interns,enhancing personal protective awareness,and lastly achieving the role transition from intern to doctor.

关键词： COVID-19 Clinical medicine Internship Teaching management

MITF基因缺失突变致Waardenburg综合征2A型1例

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

临床与病理杂志 2024年第1期44卷 141-146页

作者：宋彬彬邓幼平武汉大学中南医院儿科武汉430071

Waardenburg综合征(Waardenburg syndrome,WS)是一种常染色体显形遗传疾病,以毛发、皮肤、眼睛色素异常以及感音神经性听力障碍为特征。本文报告1例8月龄男患儿,表现为先天性耳聋伴双侧虹膜灰蓝色、毛发颜色偏黄、内眦外移。患儿及其家... 详细信息

Waardenburg综合征(Waardenburg syndrome,WS)是一种常染色体显形遗传疾病,以毛发、皮肤、眼睛色素异常以及感音神经性听力障碍为特征。本文报告1例8月龄男患儿,表现为先天性耳聋伴双侧虹膜灰蓝色、毛发颜色偏黄、内眦外移。患儿及其家系成员均进行基因测序分析。基因检测结果表明患儿存在MITF基因的c.970_972del(p.R324del)杂合变异,为新生变异;患儿父母该位点均无变异。根据美国医学遗传学与基因组学学会(American College of Medical Genetics and Genomics,ACMG)指南判读该变异为致病变异。MITF基因c.970_972del(p.R324del)在WS2A型中为一新发突变位点,是导致该患儿患病的致病基因。

关键词： Waardenburg综合征2A型 MITF基因耳聋突变

维普期刊数据库博看期刊

在线全文

学校读者我要写书评

暂无评论

新工科背景下数字电子技术实验教学模式探索

实验室科学 2024年第3期27卷 68-71页

作者：刘波宋彬彬南开大学电子信息与光学工程学院天津300350 天津理工大学计算机科学与工程学院天津300384

数字电子技术是电子信息专业学生必修的主干课程,也是新工科专创融合的重点。其中数字电路的实验实践环节是培养学生理论联系实际、具备数字系统工程设计能力的关键。以面向实际应用的数字电路课程设计为引导,依托虚拟仿真,验证实操实验... 详细信息

数字电子技术是电子信息专业学生必修的主干课程,也是新工科专创融合的重点。其中数字电路的实验实践环节是培养学生理论联系实际、具备数字系统工程设计能力的关键。以面向实际应用的数字电路课程设计为引导,依托虚拟仿真,验证实操实验,参加创新竞赛为提升,形成应用导向、理论支持、实践验证和以赛促教相结合的闭环实验教学模式,对于改进工程教育模式,特别是提高电子信息专业学生的实践能力和创新能力,具有重要的理论和实践意义。

关键词：数字电子技术实验教学模式新工科课程设计创新创业

The studies of PLGA nanoparticles loading atorvastatin calcium for oral administration in vitro and in vivo

在线全文

学校读者我要写书评

暂无评论

Asian Journal of Pharmaceutical Sciences 2017年第3期12卷 285-291页

作者： Zhenbao Li Wenhui Tao Dong Zhang Chunnuan Wu binbin song Shang Wang Tianyang Wang Mingming Hu Xiaohong Liu Yongjun Wang Yinghua Sun Jin Sun School of Pharmacy Shenyang Pharmaceutical UniversityNo.103Wenhua RoadShenyang 110016China Tianjin Medical University Cancer Hospital Tianjin 300060China China Resources Double-crane Pharmaceutical Co. Ltd.No.1Wangjing Lize East RoadChaoyang DistrictBeijingChina. Municipal Key Laboratory of Biopharmaceutics School of PharmacyShenyang Pharmaceutical UniversityNo.103Wenhua RoadShenyang 110016China

A biodegradable poly(lactic-co-glycolic acid) loading atorvastatin calcium(AC) nanoparticles(AC-PLGA-NPs) were prepared by probe ultrasonication and evaporation method aiming at improving the oral bioavailability of AC. The effects of experimental parameters, including stabilizer species, stabilizer concentration and pH of aqueous phase, on particle size were also evaluated. The resultant nanoparticles were in spherical shape with an average diameter of 174.7 nm and a narrow particle size distribution. And the drug loading and encapsulation efficiency were about 8% and 71%, respectively. The particle size and polydispersion were almost unchanged in 10 days. The release curves of AC-PLGA-NPs in vitro displaying sustained release characteristics indicated that its release mechanisms were matrix erosion and diffusion. The pharmacokinetic study in vivo revealed that the Cmax and AUC0-∞ of AC-PLGA-NPs in rats were nearly 3.7-fold and 4.7-fold higher than that of pure atorvastatin calcium suspension. Our results demonstrated that the delivery of AC-PLGANPs could be a promising approach for the oral delivery of AC for enhanced bioavailability.

关键词： Atorvastatin calcium AC-PLGA-NPs Probe ultrasonication and evaporation method Oral bioavailability

Ultra-large mode area multi-core orbital angular momentum transmission fiber designed by neural network and optimization algorithms

在线全文

学校读者我要写书评

暂无评论

Optoelectronics Letters 2023年第12期19卷 744-751页

作者： GU Zhiwei HUANG Wei ZHANG Ran FAN Junjie song binbin Key Laboratory of Computer Vision and Systems(Ministry of Education) School of Computer Science and EngineeringTianjin University of TechnologyTianjin 300384China Engineering Research Center of Learning-Based Intelligent System(Ministry of Education) Tianjin University of TechnologyTianjin 300384China

A large mode area multi-core orbital angular momentum(OAM)transmission fiber is designed and optimized by neural network and optimization algorithms.The neural network model has been established first to predict the optical properties of multi-core OAM transmission fibers with high accuracy and speed,including mode area,nonlinear coefficient,purity,dispersion,and effective index difference.Then the trained neural network model is combined with different particle swarm optimization(PSO)algorithms for automatic iterative optimization of multi-core structures respectively.Due to the structural advantages of multi-core fiber and the automatic optimization process,we designed a number of multi-core structures with high OAM mode purity(>95%)and ultra-large mode area(>3000µm^(2)),which is larger by more than an order of magnitude compared to the conventional ring-core OAM transmission fibers.

关键词： network fiber OAM

A statistical analysis of the Kappa-type energy spectrum distribution of radiation belt electrons observed by Van Allen Probes

在线全文

学校读者我要写书评

暂无评论

Earth and Planetary Physics 2024年第2期8卷 368-374页

作者： LuHuai Jiao Xin Ma YuanNong Zhang TaiFeng Jin song Fu binbin Ni Department of Space Physics School of Electronic InformationWuhan UniversityWuhan 430072China

The energy spectrum of energetic electrons is a key factor representing the dynamic variations of Earth’s Van Allen radiation belts.Increased measurements have indicated that the commonly used Maxwellian and Kappa distributions are inadequate for capturing the realistic spectral distributions of radiation belt electrons.Here we adopt the Kappa-type(KT)distribution as the fitting function and perform a statistical analysis to investigate the radiation belt electron flux spectra observed by the Van Allen Probes.By calculating the optimal values of the key KT distribution parameters(i.e.,κandθ2)from the observed spectral shapes,we fit the radiation belt electron fluxes at different L-shells under different geomagnetic conditions.In this manner,we obtain typical values of the KT distribution parameters,which are statistically feasible for modeling the radiation belt electron flux profiles during either geomagnetically quiet or active periods.A comparison of the KT distribution model results with those using the Maxwellian or Kappa distribution reveals the advantage of the KT distribution for studying the overall properties of the radiation belt electron spectral distribution,which has important implications for deepening the current understanding of the radiation belt electron dynamics under evolving geomagnetic conditions.

关键词： radiation belt electron Kappa-type distribution fitting geomagnetic storm

Whole genome sequencing of 10K patients with acute ischaemic stroke or transient ischaemic attack: design, methods and baseline patient characteristics

在线全文

学校读者我要写书评

暂无评论

Stroke & Vascular Neurology 2021年第2期6卷 291-297页

作者： Si Cheng Zhe Xu Yang Liu Jinxi Lin Yong Jiang Yilong Wang Xia Meng Anxin Wang Xinying Huang Zhimin Wang Guohua Chen songdi Wu Zhengchang Jia Yongming Chen Xuerong Qiu Jun Wu binbin song Weizhong Ji Zhongping An Wenjun Xue Lili Zhao Yu Geng Hongyan Li Hao Li Yongjun Wang Department of Neurology Beijing Tiantan HospitalCapital Medical UniversityBeijingChina China National Clinical Research Center for Neurological Diseases BeijingChina Advanced Innovation Center for Human Brain Protection Capital Medical UniversityBeijingChina Department of Neurology The First people's Hospital of TaizhouTaizhouChina Department of Neurology Wuhan First HospitalWuhanChina Department of Neurology The First People's Hospital of Xi'anXi'anChina Department of Neurology The Second People’s Hospital of JinzhongJinzhongChina Department of Neurology WuYuan County People’s HospitalBayannurChina Department of Neurology Qiqihar City Rongjian Stroke Prevention and Treatment InstituteQiqiharChina Department of Neurology Peking University Shenzhen HospitalShenzhenChina Department of Neurology Luoyang Central HospitalLuoyangChina Department of Neurology Qinghai Provincial People's HospitalXiningChina Department of Neurology Tianjin Huanhu HospitalTianjinChina Department of Neurology Pingdingshan First People's HospitalPingdingshanChina Department of Neurology Changzhi People's HospitalChangzhiChina Department of Neurology Zhejiang Provincial People's HospitalHangzhouChina Department of Neurology Xinjiang Uygur Autonomous Region People's HospitalUrumqiChina

Background and purpose Stroke is the second leading cause of death worldwide and the leading cause of mortality and long-term disability in China,but its underlying risk genes and pathways are far from being comprehensively understood.We here describe the design and methods of whole genome sequencing(WGS)for 10914 patients with acute ischaemic stroke or transient ischaemic attack from the Third China National Stroke Registry(CNSR-III).Methods Baseline clinical characteristics of the included patients in this study were reported.DNA was extracted from white blood cells of participants.Libraries are constructed using qualified DNA,and WGS is conducted on BGISEQ-500 platform.The average depth is intended to be greater than 30×for each subject.Afterwards,Sentieon software is applied to process the sequencing data under the Genome Analysis Toolkit best practice guidance to call genotypes of single nucleotide variants(SNVs)and insertion-deletions.For each included subject,21 fingerprint SNVs are genotyped by MassARRAY assays to verify that DNA sample and sequencing data originate from the same individual.The copy number variations and structural variations are also called for each patient.All of the genetic variants are annotated and predicted by bioinformatics software or by reviewing public databases.Results The average age of the included 10914 patients was 62.2±11.3 years,and 31.4%patients were women.Most of the baseline clinical characteristics of the 10914 and the excluded patients were balanced.Conclusions The WGS data together with abundant clinical and imaging data of CNSR-III could provide opportunity to elucidate the molecular mechanisms and discover novel therapeutic targets for stroke.

关键词： patients transient characteristics

电磁脉冲应力下MOSFET器件退化机制研究

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

集成电路与嵌入式系统 2024年第5期24卷 55-59页

作者：宋斌斌王凯鹿祥宾单书珊罗宗兰栗磊赫嘉楠北京芯可鉴科技有限公司北京102200 国网宁夏电力有限公司电力科学研究院银川750011

针对电力应用场景中电磁脉冲导致芯片性能异常退化、芯片内MOSFET(Metal Oxide Semiconductor Field Effect Transistor)等器件失效机理不清晰等问题,本研究采用幅值和宽度分别为8 V和100 ns的TLP(Transmission Line Pulse)脉冲施加至5 ... 详细信息

针对电力应用场景中电磁脉冲导致芯片性能异常退化、芯片内MOSFET(Metal Oxide Semiconductor Field Effect Transistor)等器件失效机理不清晰等问题,本研究采用幅值和宽度分别为8 V和100 ns的TLP(Transmission Line Pulse)脉冲施加至5 V NMOS器件栅氧层,测量了不同脉冲循环次数下器件输出特性曲线I d V d和转移特性曲线I d V g,通过分析不同TLP脉冲条件下跨导的变化规律研究了阈值电压和载流子迁移率随TLP脉冲个数的退化规律。研究结果表明,相同漏电压V d和栅极电压V g下,器件漏电流I d随TLP脉冲次数的增加而升高;TLP脉冲导致阈值电压V T降低显著,施加20000次TLP脉冲后V T降低约25.66%;TLP脉冲造成器件阈值电压的变化量呈指数升高,通过拟合指数为0.11~0.15;TLP脉冲对沟道内载流子迁移率的影响不明显。

关键词：金属氧化物半导体场效应管电磁脉冲阈值电压跨导迁移率

维普期刊数据库博看期刊

Ultrathin GaN Film Derived from Amorphous Ga_(2)O_(3) Film

在线全文

学校读者我要写书评

暂无评论

Journal of Wuhan University of Technology(Materials Science) 2024年第4期39卷 814-818页

作者：王鹏 ZHANG binbin LIU Xiaofei ZHANG Xin TU Rong ZHANG song 李宝文 State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of TechnologyWuhan 430070China State Key Laboratory of Silicate Materials for Architectures School of Materials Science and EngineeringWuhan University of TechnologyWuhan 430070China

It remains a big challenge to synthesize two-dimensional(2D)GaN material for applications in power nanodevices.Traditional synthetic methods require complex equipment and processes and time consuming.Here,we reported a two-step route to prepare polycrystalline 2D GaN film.The amorphous ultrathin Ga_(2)O_(3)film was first exfoliated from the surface of liquid gallium.In a vapor phase reaction,2D Ga_(2)O_(3)film was then converted into 2D GaN film while maintaining the 2D morphology.Raman and high-resolution transmission electron microscope(HRTEM)analysis implies the successful synthesis of wurtzite-type GaN ultrathin film.This simple strategy proposed in this work will provide more opportunities for applications of GaN ultrathin film in many devices.

关键词： GaN Ga_(2)O_(3) liquid gallium