检索结果-南通市图书馆

维普期刊数据库博看期刊

Experimental and Computational Analysis of the Solution and Solid-State Conformations of Hexadepsipeptides from Beauveria felina

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Chemistry 2022年第3期40卷 378-384页

作者： Feng-Yu Du Attila Mandi Xiao-Ming Li Ling-Hong meng Tibor kurtan bin-Gui Wang CAS&Shandong Province key Laboratory of Experimental Marine Biology Institute of OceanologyChinese Academy of Sciencesand Laboratory of Marine Biology and BiotechnologyQingdao National Laboratory for Marine Science and TechnologyNonhoi Rood 7QingdaoShandong 266071China College of Chemistry and Pharmacy Qingdao Agricultural UniversityQingdooShandong 266109China Department of Organic Chemistry University of DebrecenPOB 4004002 DebrecenHungary College of Marine Science University of Chinese Academy of SciencesYuquon Rood 19ABeijing 100049China Center for Ocean mego-Science Chinese Academy of SciencesNonhoi Road 7t QingdaoShandong 266071China

Chemical investigation of Beouverio felina,a marine-derived entomopathogenic fungus,obtained two new destruxin hexadepsipeptides(1 and 2)containing an/.-Ala^(5)residue instead of the usual A/-me-L-Ala^(5).Interestingly,the presence of the/.-Ala^(5)residue enabled two slowly-exchanging solution conformers with cis/trons(ILE^(3))-(A/-me-Val^(4))amide bond for 1 and 2 with 1.5:1 and 1:1 cis/trans ratios,respectively,while only the conformer with c/s amide bond was found in the *** solution and solid-state conformers were studied by nMR,X-ray diffraction and solution and solid-state ECD measurements,as well as by TDDFT-ECD ***(conformational)parameter-activity correlations suggested that the extended destruxin geometry with the preferred c/s(ILE^(3))-(A/-me-Val^(4))bond probably resulted in improved bioactivity and reduced toxicity for the destruxin *** was the first report on the interconversion phenomenon of cis/trans amide bonds of destruxin class,which could give insights in the development of bioactive destruxin agents with lower toxicity.

关键词： Beouveria felina natural products Destruxin hexadepsipeptides Structure elucidation Conformation analysis

窄带光成像放大内镜联合卢戈氏碘染色试验在食管早癌浸润深度预测中的应用研究

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中国医疗器械信息 2024年第6期30卷 79-81页

作者：刘炎陆晶赖文斌福建医科大学附属闽东医院消化内科福建福安355000

目的:分析窄带光成像放大内镜(nBI-me)联合卢戈氏碘染色试验(LCE)在食管早癌浸润深度预测中的应用。方法:回顾性分析2019年1月~2022年10月在本院收治的疑似食管早癌并行ESD治疗的患者共58例,分别采用nBI-me(n=26)和nBI-me联合LCE(n=32)... 详细信息

目的:分析窄带光成像放大内镜(nBI-me)联合卢戈氏碘染色试验(LCE)在食管早癌浸润深度预测中的应用。方法:回顾性分析2019年1月~2022年10月在本院收治的疑似食管早癌并行ESD治疗的患者共58例,分别采用nBI-me(n=26)和nBI-me联合LCE(n=32)检查。以病理检查的结果作为检验的标准,使用kappa(k值)一致性分析nBI-me联合LCE检查对食管早癌以及浸润深度的临床诊断应用价值。结果:nBI-me联合LCE的检出率明显高于单纯nBI-me检查(90.63%vs 69.23%),PnBI-me、nBI-me联合LCE预测浸润深度的准确率各为83.33%、89.66%,敏感度各为86.67%、91.67%,特异度各为66.67%、80.00%,kappa值各为0.471、0.664。结论:nBI-me与LCE联合应用于食管早癌的诊断与浸润深度的预测有一定的价值。

关键词：窄带光成像放大内镜卢戈氏碘染色试验食管早癌浸润深度

Efficient separation of C_(4) olefins using tantalum pentafluor oxide anion-pillared hybrid microporous material

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Chemical Engineering 2022年第2期35卷 49-54页

作者： bin Gao Zhaoqiang Zhang Jianbo Hu Jiyu Cui Liyuan Chen Xili Cui Huabin Xing key Laboratory of Biomass Chemical Engineering of Ministry of Education College of Chemical and Biological EngineeringZhejiang UniversityHangzhou 310027China Hangzhou Global Scientific and Technological Innovation Center Zhejiang UniversityHangzhou 311215China

With the increasing demand for synthetic rubber,the purification of 1,3-butadiene(C_(4)H_(6))is of great industrial ***,the successful removal of n-butene(n-C_(4)H_(8))and iso-butene(iso-C_(4)H_(8))from 1,3-butadiene(C_(4)H_(6))was realized by synthesizing a novel taOF_(5)^(2-) anion-pillared ultramicroporous material taOFFIVE-3-ni(also referred to as ZU-96,taOFFIVE=taOF_(5)^(2-),3=pyrazine).Single-component adsorption isotherms show that taOFFIVE-3-ni can achieve the exclusion of n-C_(4)H_(8) and iso-C_(4)H_(8) in the low pressure region(0–30 kPa),and uptake C_(4)H_(6) with a high capacity of 92.78 cm^(3)·cm^(-3)(298 k and 100 kPa).The uptake ratio of C_(4)H_(6)/iso-C_(4)H_(8) on taOFFIVE-3-ni was 20.83(298 k and 100 kPa),which was the highest among the state-of-the-art adsorbents reported so *** the rotation of anion and pyrazine ring,the pore size changes continuously,which makes smaller-size C_(4)H_(6) enter the channel while larger-size n-C_(4)H_(8) and iso-C_(4)H_(8) are completely *** excellent breakthrough performance of taOFFIVE-3-ni shows great potential in industrial separation of C4 *** specific adsorption binding sites within ZU-96 was further revealed through the modeling calculation.

关键词： Adsorptive separation C4 olefin 13-Butadiene Anion-pillared hybrid microporous material

The integrated monitoring system for running parameters of key mining equipment based on condition monitoring technology

在线全文

学校读者我要写书评

暂无评论

Journal of Coal Science & Engineering(China) 2010年第1期16卷 108-112页

作者： bin Guang-fu LI Xue-jun BALBIR S Dhillon HUAnG Zhen-yu GUO Deng-ta key Lab of Health Maintenance for mechanical Equipment of Hunan Province Hunan University of Science and Technology Xiangtan 411201 China Department of mechanical Eng. Univ/Ottawa Ottawa K1B 6N5 Canada Xiangtan Liangchuan Coal Mine Machine Co. Ltd. Xiangtan 411104 China Xiangtan Electric Manufacturing Corporation Ltd. Xiangtan 411101 China

An integrated monitoring system for running parameters of key mining equipmenton the basis of condition monitoring technology and modern communication networktechnology was *** system consists of a client computer with functions ofsignal acquisition and processing, and a host computer in the central control *** acquisition module of the client computer can collect the running parameters fromvarious monitoring terminals in *** DSP high-speed data processing system ofthe main control module can quickly achieve the numerical calculation for the *** signal modulation and signal demodulation are completed by the frequencyshift keying circuit and phase-locked loop frequency circuit, ***, the signalis sent to the host computer for logic estimation and diagnostic analysis using the networkcommunication technology, which is helpful for technicians and managers to control therunning state of equipment.

关键词：综合监测系统状态监测技术运行参数关键参数采矿设备基础计算机采集通信网络技术

Weighted Multi-sensor Data Level Fusion method of Vibration Signal Based on Correlation Function

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of mechanical Engineering 2011年第5期24卷 899-904页

作者： bin Guangfu JIAnG Zhinong LI Xuejun DHILLOn B S Diagnosis and Self-recovery Engineering Research Center Beijing University of Chemical Technology Beijing 100029 China Hunan Provincial key Laboratory of Health Maintenance for mechanical Equipment Hunan University of Science and Technology Xiangtan 411201 China Department of mechanical Engineering University of Ottawa 161 Louis Pasteur Ottawa K1B 6N5 Canada

As the differences of sensor＇s precision and some random factors are difficult to control,the actual measurement signals are far from the target signals that affect the reliability and precision of rotating machinery fault *** traditional signal processing methods,such as classical inference and weighted averaging algorithm usually lack dynamic adaptability that is easy for trends to cause the faults to be misjudged or left *** enhance the measuring veracity and precision of vibration signal in rotary machine multi-sensor vibration signal fault diagnosis,a novel data level fusion approach is presented on the basis of correlation function analysis to fast determine the weighted value of multi-sensor vibration *** approach doesn＇t require knowing the prior information about sensors,and the weighted value of sensors can be confirmed depending on the correlation measure of real-time data tested in the data level fusion *** gives greater weighted value to the greater correlation measure of sensor signals,and vice *** approach can effectively suppress large errors and even can still fuse data in the case of sensor failures because it takes full advantage of sensor＇s own-information to determine the weighted ***,it has good performance of anti-jamming due to the correlation measures between noise and effective signals are usually *** the simulation of typical signal collected from multi-sensors,the comparative analysis of dynamic adaptability and fault tolerance between the proposed approach and traditional weighted averaging approach is ***,the rotor dynamics and integrated fault simulator is taken as an example to verify the feasibility and advantages of the proposed approach,it is shown that the multi-sensor data level fusion based on correlation function weighted approach is better than the traditional weighted average approach with respect to fusion precision and dynamic ***,the approac

关键词： vibration signal multi-sensor data level fusion correlation function weighted value

Dose rate effects on shape memory epoxy resin during 1 me V electron irradiation in air

在线全文

学校读者我要写书评

暂无评论

Journal of Materials Science & Technology 2021年第8期67卷 61-69页

作者： Longyan Hou Yiyong Wu Debin Shan bin Guo Yingying Zong State key Laboratory of Advanced Welding and Joining Harbin Institute of TechnologyHarbin 150001China national key Laboratory of Materials Behavior and Evaluation Technology in Space Environments Harbin Institute of TechnologyHarbin 150001China

The effects of 1 me V electron irradiation in air at a fixed accumulated dose and dose rates of 393.8,196.9,78.8,and 39.4 Gy s^(-1)on a shape memory epoxy(SmeP)resin were *** low-dose-rate irradiation,accelerated degradation of the shape memory performance was observed;specifically,the shape recovery ratio decreased exponentially with increasing irradiation time(that is,with decreasing dose rate).In addition,the glass transition temperature of the SmeP,as measured by dynamic mechanical analysis,decreased overall with decreasing dose *** dose rate effects of 1 me V electron irradiation on the SmeP were confirmed by structural analysis using electron paramagnetic resonance(EPR)spectroscopy and Fourier transform infrared(FTIR)*** EPR spectra showed that the concentration of free radicals increased exponentially with increasing irradiation ***,the FTIR spectra showed higher intensities of the peaks at 1660 and 1720 cm^(-1),which are attributed to stretching vibrations of amide C=O and ketone/acid C=O,at lower dose *** intensities of the IR peaks at 1660 and 1720 cm^(-1) increased exponentially with increasing irradiation time,and the relative intensity of the IR peak at 2926 cm^(-1)decreased exponentially with increasing irradiation *** solid-state13 C nuclear magnetic resonance(nMR)spectra of the SmeP before and after 1 me V electron irradiation at a dose of 1970 k Gy and a dose rate of 78.8 Gy s^(-1) indicated damage to the CH_(2)–n groups and aliphatic isopropanol *** result is consistent with the detection of nitrogenous free radicals,a phenoxy-type free radical,and several types of pyrolytic carbon radicals by *** the subsequent propagation process,the free radicals produced at lower dose rates were more likely to react with oxygen,which was present at higher concentrations,and form the more destructive peroxy free radicals and oxidation products such as acids,amides,and *** increase in peroxy

关键词： Shape memory epoxy resin Shape memory effect Electron irradiation Dose rate effect Free radical Chain scission

Photoluminescence properties and thermal stability of Eu^(3+)-activated La_(7)ta_(3)W_(4)O_(30) red-emitting phosphors for near-UV-excited w-LEDs

在线全文

学校读者我要写书评

暂无评论

Journal of Rare Earths 2021年第8期39卷 905-912页

作者： Yu Ren bin Deng Ting Liang Shuang Shu Junlan Guo Shoucheng Zhao Ruijin Yu College of Chemistry&Pharmacy Northwest A&F UniversityYangling 712100China College of Chemistry&Biology and Environmental Engineering Xiangnan UniversityChenzhou 423043China Hunan Provincial key Laboratory o/Xiangnan Rare-Precious metals Compounds Research and Application Xiangtan UniversityChenzhou 423043China College of Materials and Chemical Engineering Key Laboratory of Inorganic Nonmetallic Crystalline and Energy Conversion MaterialsChina Three Gorges UniversityYichang 443002China

novel trivalent europium(Eu^(3+))-activated La_(7)ta_(3)W_(4)O_(30):xEu^(3+)(x=0.5 mol%-40 mol%) red-emitting phosphors were synthesized by means of a high-temperature solid-state *** structure,morphology,photoluminescence,thermal-stability properties,lifetime,and color-rendering of the prepared phosphors were investigated in *** La_(7)ta_(3)W_(4)O_(30):Eu^(3+) phosphors show five emission peaks under near-ultraviolet(n-UV) at 397 nm,and these peaks are ascribed to the transitions of ^(5)D0-^(7)Fj(j=0,1,2,3 and 4) by Eu^(3+) *** optimal doping concentration of Eu^(3+) is 20 mol%,and the critical distance of the energy transfer between the Eu^(3+)ions was calculated to be 1.768 *** quenching temperature(T_(0.5)) of La_(7)ta_(3)W_(4)O_(30):20 mol%Eu^(3+) is about 440 *** quantum yield(QY) was measured to be 85.85%.The fabricated white-light-emitting diodes(w-LEDs) possess high color-rendering index(R_(a)) of 90,and high correlated color temperature(CCT) of 5810 k,*** Commission Internationale de L’Eclairage(CIE) coordinates are(0.311,0.322).Therefore,the prepared phosphor has a promising application for w-LEDs.

关键词： Luminescence Phosphor Tungstate La_(7)ta_(3)W_(4)O_(30) Rare earths

meTTL14 is a chromatin regulator independent of its RnA n^(6)-methyladenosine methyltransferase activity

在线全文

学校读者我要写书评

暂无评论

Protein & Cell 2023年第9期14卷 683-697页

作者： Xiaoyang Dou Lulu Huang Yu Xiao Chang Liu Yini Li Xinning Zhang Lishan Yu Ran Zhao Lei Yang Chuan Chen Xianbin Yu Boyang Gao meijie Qi Yawei Gao bin Shen Shuying Sun Chuan He Jun Liu Department of Chemistry and Institute for Biophysical Dynamics University of ChicagoChicagoIL 60637USA Howard Hughes medical Institute ChicagoIL 60637USA State key Laboratory of Protein and Plant Gene Research Peking-Tsinghua Center for Life SciencesSchool of Life SciencesPeking UniversityBeijing 100871China Department of Physiology and Brain Science Institute Johns Hopkins University School of MedicineBaltimoreMD 21205USA Institute for Regenerative medicine Shanghai East HospitalShanghai Key Laboratory of Signaling and Disease ResearchFrontier Science Center for Stem Cell ResearchSchool of Life Sciences and TechnologyTongji UniversityShanghai 200120China The Institute of Translational medicine School of MedicineZhejiang UniversityHangzhou 310029China Division of Life Sciences and medicine Center for Reproductive MedicineThe First Affiliated Hospital of USTCUniversity of Science and Technology of ChinaHefei230000China Clinical and Translational Research Center of Shanghai First Maternity&Infant Hospital Shanghai Key Laboratory of Signaling and Disease ResearchFrontier Science Center for Stem Cell ResearchSchool of Life Sciences and TechnologyTongji UniversityShanghai 200092China State key Laboratory of Reproductive medicine Center for Global HealthGusu SchoolWomen's Hospital of Nanjing Medical UniversityNanjing Maternity and Child Health Care HospitalNanjing Medical UniversityNanjing211166China Department of Biochemistry and Molecular Biology University of ChicagoChicagoIL 60637USA

meTTL3 and meTTL14 are two components that form the core heterodimer of the main RnA m^(6)A methyltransferase complex(MTC)that installs m^(6)***,depletion of meTTL3 or meTTL14 displayed distinct effects on stemness maintenance of mouse embryonic stem cell(meSC).While comparable global hypo-methylation in RnA m^(6)A was observed in mettl3 or mettl14 knockout meSCs,***14 knockout led to a globally decreased nascent RnA synthesis,whereas mettl3 depletion resulted in transcription upregulation,suggesting that meTTL14 might possess an mA-independent role in gene *** found that meTTL14 colocalizes with the repressive H3k27me3 ***,meTTL14,but not meTTL3,binds H3k27me3 and recruits kDM6B to induce H3k27me3 demethylation independent of *** of meTTL14 thus led to a global increase in H3k27me3 level along with a global gene *** effects of meTTL14 on regulation of H3k27me3 is essential for the transition from self-renewal to differentiation of *** work reveals a regulatory mechanism on heterochromatin by meTTL14 in a manner distinct from meTTL3 and independently of m^(6)A,and critically impacts transcriptional regulation,stemness maintenance,and differentiation ofmeSCs.

关键词： meTTL14 chromatin H3k27me3 m^(6)A-independent meSC differentiation

Geochemistry,Geochronology,Sr-nd Isotopic Compositions of Jiang Tso Ophiolite in the Middle Segment of the Bangong- nujiang Suture Zone and Their Geological Significance

在线全文

学校读者我要写书评

暂无评论

Acta Geologica Sinica(English Edition) 2015年第2期89卷 389-401页

作者： HUAnG Qiangtai LI Jianfeng CAI Zhourong XIA Lianze YUAn Yajuan LIU Huichuan XIA bin School of Marine sciences Sun Yat-Sen University key Laboratory of Offshore Oil Exploration and Development Guangdong University Guangdong Provincial key Laboratory of Marine Resources and Coastal Engineering Guangzhou Institute of Geochemistry Chinese Academy of Sciences School of Earth Science and Geological Engineering Sun Yat-sen University

The Jiang Tso ophiolite, situated in the middle segment of the Bangong- nujiang Suture Zone, is a part of the easternmost Qieli Lake ophiolite subzone and is close to the south of Pung Lake ophiolite. The rock association of Jiang Tso ophiolite is relatively complete and is mainly composed of metamorphic peridotite, gabbro and diabase. Comparing with n-MORB, the ophiolite is high in Mg and low in Ti, k, na, P, and is depleted in nb, ta, Hf, Th and enriched in Rb, Sr and Ba. Geochemical characteristics of the Jiang Tso ophiolite indicate it is of a supra-subduction zone type formed in the spreading ridge of back arc basin. The SHRIMP U-Pb dating of zircons from the gabbro yielded a weighted average age of 188.1±4.1 Ma （MSWD=1.4）, indicating the Jiang Tso ophiolite was formed in the late stage of early Jurassic. The Sr, nd isotopic compositions show that the Tethyan mantle domain is the depleted mantle （DM）, with enriched mantle domain II （EMII）. They have the same Sr, nd isotopic composition with the India Ocean MORB type.

关键词： geochemistry SHRIMP U-Pb dating Sr-nd isotopes tectonic environment Tibet