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Joint TDOA and AOA location algorithm

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Journal of Systems Engineering and Electronics 2013年第2期24卷 183-188页

作者： Congfeng Liu jie Yang Fengshuai wang Institute of Electronic Countermeasure Xidian University School of Communication and Information Xi'an University of Posts and Telecommunications The 54th Institute of China Electronics Technology Group Corporation

For the joint time difference of arrival（TDOA） and angle of arrival（AOA） location scene,two methods are proposed based on the rectangular coordinates and the polar coordinates,*** problem is solved perfectly by calculating the target position with the joint TDOA and AOA *** the condition of rectangular coordinates,first of all,it figures out the radial range between target and reference stations,then calculates the location of the *** the case of polar coordinates,first of all,it figures out the azimuth between target and reference stations,then figures out the radial range between target and reference stations,finally obtains the location of the ***,simulation analyses show that the theoretical analysis is correct,and the proposed methods also provide the application of the joint TDOA and AOA location algorithm with the theoretical basis.

关键词： passive location joint time difference of arrival (TDOA)and angle of arrival (AOA) location direct solution method perfor-mance analysis.

AN EXTENDED AGGREGATED RATIO ANALYSIS IN DEA

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Journal of Systems Science and Systems Engineering 2011年第2期20卷 249-256页

作者： Malin SONG jie WU Yumei wang School of Statistics and Applied Mathematics Anhui University of Finance & Economics Bengbu 233030 China School of Management University of Science & Technology of China HefeL 230026 China

Data Envelopment Analysis（DEA） and Ratio Analysis（RA） are two widely used methods for measuring units＇ productivity and any other criteria that could be assessed based on the available input and output variables.A number of researchers have studied DEA and RA and noted the positive and negative differences between *** ratio analysis（ARA） model,which provide an important linkage between DEA and RA theory,is equivalent to the CCR DEA model,and this equivalence property offers a great deal of opportunities for DEA to be interpreted and applied in different *** paper extends the results of ARA model and proposes an extended aggregated ratio analysis（EARA） model,similar as the development from CCR model to BCC model in DEA *** proposed model can offer an insight into the characteristic of returns to scale,playing the corresponding role as BCC model *** numerical example is revisited in the paper and the results are compared.

关键词： Data Envelopment Analysis(DEA) aggregated ratio analysis efficiency evaluation returns to scale

电针预处理对促排卵大鼠子宫组织核心时钟基因Bmal1表达节律的影响

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针刺研究 2024年第7期49卷 743-750页

作者：朱钱刘静玉郝赛楠王照弦夏良君沈洁程洁李茜夏有兵南京中医药大学针灸推拿学院·养生康复学院南京210023 南京中医药大学针药结合教育部重点实验室南京210023 徐州医科大学江苏徐州221004

目的:观察电针预处理对促排卵大鼠子宫组织中时钟基因Bmal1表达节律的影响,探讨电针预处理提高促排卵大鼠植入期子宫内膜容受性的作用机制。方法:将72只雌性SD大鼠按随机数字表法分为正常组、模型组和预电针组,每组24只。除正常组外,其... 详细信息

目的:观察电针预处理对促排卵大鼠子宫组织中时钟基因Bmal1表达节律的影响,探讨电针预处理提高促排卵大鼠植入期子宫内膜容受性的作用机制。方法:将72只雌性SD大鼠按随机数字表法分为正常组、模型组和预电针组,每组24只。除正常组外,其余2组大鼠腹腔注射孕马血清促性腺激素48 h后腹腔注射人绒毛促性腺激素制备促排卵模型。预电针组选取“关元”“三阴交”,于造模前两个动情周期每日21:00电针干预,每次15 min,直至造模结束。正常组大鼠动情期与输精管结扎雄鼠合笼,其余两组造模结束当日合笼。3组大鼠于合笼成功后第5天4:00起每隔4 h每批每组4只进行取材,共分6批。HE染色观察子宫内膜厚度、腺体和血管数目及组织形态变化;ELISA法检测血清雌二醇(E2)与孕酮(Pg)含量;实时荧光定量PCR法检测子宫核心时钟基因Bmal1和子宫内膜容受性因子HoxA10、白血病抑制因子(LIF)的mRNA表达;Western blot法检测子宫组织HoxA10、LIF蛋白表达。结果:与正常组相比,模型组子宫内膜厚度变薄(P<0.01),腺体和血管的数量显著减少(P<0.01,P<0.05);子宫Bmal1节律表达峰值和谷值的表达时点与正常组相反,12:00和16:00时Bmal1 mRNA表达下降(P<0.01);血清E2、Pg含量显著提高(P<0.01,P<0.05);内膜容受性因子HoxA10和LIF的mRNA和蛋白表达水平显著降低(P<0.01,P<0.05)。与模型组相比,预电针组子宫内膜厚度、腺体和血管的数量均显著增加(P<0.05);子宫Bmal1节律表达的峰谷值回调,其表达水平也有所增加,其中12:00时3组的表达差异最为显著,12:00时预电针组Bmal1表达较模型组显著升高(P<0.05);血清Pg含量显著降低(P<0.05);容受性因子HoxA10和LIF的mRNA和蛋白水平升高(P<0.05,P<0.01)。结论:电针预处理能够改善种植窗口期子宫内膜容受性,其机制可能是调节子宫组织时钟基因Bmal1的节律表达,纠正促排导致的时钟基因表达的节律紊乱。

关键词：电针预处理控制性超排卵昼夜节律时钟基因 Bmal1

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青海草原毛虫IR基因的鉴定及组织表达分析

草地学报 2024年第5期32卷 1392-1400页

作者：刘占玲寇桂香南彦斌王克鑫周渊涛青海大学农牧学院青海西宁810016

本研究利用生物信息学分析及qRT-PCR技术,对GqinIRs基因进行鉴定及表达谱分析。本研究共鉴定出12个GqinIRs基因,生物信息学分析发现青海草原毛虫IRs属于两性蛋白,除GqinIR7、GqinIR8a、GqinIR10a、GqinIR75a、GqinIR76b都具有信号肽,具... 详细信息

本研究利用生物信息学分析及qRT-PCR技术,对GqinIRs基因进行鉴定及表达谱分析。本研究共鉴定出12个GqinIRs基因,生物信息学分析发现青海草原毛虫IRs属于两性蛋白,除GqinIR7、GqinIR8a、GqinIR10a、GqinIR75a、GqinIR76b都具有信号肽,具有2~4个跨膜结构域,二三级结构主要由α螺旋和无规则卷曲组成;系统进化表明青海草原毛虫IR与东方黏虫和疆夜蛾亲缘关系较近。基因表达谱分析表明,鉴定的青海草原毛虫12个IR基因在雌雄不同组织体现不同的表达水平(P<0.05)。本研究为进一步研究青海草原毛虫离子型受体蛋白对外界气味分子的识别及反应机制提供重要依据,并且为深入研究青海草原毛虫嗅觉机制奠定基础。

关键词：青海草原毛虫离子型受体生物信息学分析表达谱分析

Analysis of the spanwise vortex of open channel flows based on the Omega-Liutex vortex identification method

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Journal of Hydrodynamics 2022年第1期34卷 148-155页

作者： bin Li Wen-jun Yang jie Li Si-yu Jing Yue Chen Changjiang River Scientific Research Institute Wuhan430010China Fujian College of Water Conservancy and Electric Power Sanming353000China Department of Water Conservancy and Hydropower Engineering Hohai UniversityNanjing210098China

In this paper, a particle imaging velocimetry (PIV) system of high-temporal-spatial resolution is used to investigate the spanwise vortex distribution of fully developed turbulent flows in an open channel and its relationship with the turbulence. The distributions of the time-averaged velocity, the turbulence intensity and the Reynolds stress are obtained in the longitudinal profile. The third-generation vortex identification method (based on the Omega-Liutex vector) is applied to accurately identify and analyze the vortex in the spanwise direction. The results suggest that the vortex density increases with the Reynolds number at a given aspect ratio (B / H) of the flow. The distribution trend of the spanwise vortex density in the vertical direction remains unchanged for different discharges. Specifically, the vortex density increases along the vertical direction and reaches the peak at y / H = 0.15, then decreases and reaches the bottoms at the flow surface.

关键词： Open channel turbulent flows spanwise vortex Reynolds number particle imaging velocimetry(PIV) aspect ratio

World Federation of Acupuncture-Moxibustion Societies(WFAS)Clinical Practice Guideline on Acupuncture and Moxibustion:Migraine recommendation summaries

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World Journal of Acupuncture-Moxibustion 2024年第3期34卷 204-212页

作者： Wen-qian MA Shuo CUI Jing HU Zhong-jie CHEN Jin HUO Ya-ping LIU Xiao-yu wang Zi-wei SONG Qi GAO Shu-hua MA Yi ZHANG Zhong-chao WU Ji-ping ZHAO Xiang-hong JING Xiao-dong WU Yu-tong FEI bin XU Shao-zong CHEN Cheng QIAN Chun-gui YANG Dong-qing ZHANG Ling ZHAO bin LI Filomena Petti Aldo Liguori Carlos Llopis Claudia Skopalik Zhao DONG Jian YIN Zhen HUA Dong-sheng wang Gerd Lutterjohann Yue JIAO Jing-jing wang Institute of Acupuncture and moxibustion China Academy of Chinese Medical SciencesBeijing 100700China Experimental Research Center China Academy of Chinese Medical SciencesBejing100700China Dongzhimen Hospital Beijing University of Chinese MedicineBeijing 100007China School of Traditional Chinese Medicine Beijing University of Chinese MedicineBeijing 100105China Key Laboratory of the Ministry of Education for the Integration of Needle and Medicine Nanjing University of Chinese MedicineNanjing 210023China School of Acupuncture-moxibustion and Tuina Mossage Shandong University of Traditional Chinese MedicineJinan 250355China Shenzhou Open University of Traditional Chinese medicine Noord-Holland 671011 EKNetherlands Chinese Medicine Society Sweden Stockholm 10653Sweden School of Acupuncture-moxibustion and Tuina Mossage Chengdu University of Traditional Chinese MedicineChengdu 610075China Acupuncture-moxibustion Department of Beijing Hospital of Traditional Chinese Mediane Bejing 100010China Istituto Paracelso Rome 00153Italy European Foundation of Traditional Chinese Medicine Madrid 28000Spain Department of Neurology First Medical Center of Chinese PLA General HospitalBeijing 100039China Department of Neurology of Beijing Hospital Beijing 100853China Anesthesiology Department and pain diagnosis and treatment center Beijing HospitalBejing 100853China Division of Psychology of Beijing Normal University Beijing 100091China German Medical Association for Acupuncture(DAGfA) Munich 80801Germany Tsinghua University Hospital Bejing 100084China

Clinical Practice Guideline on Acupuncture and Moxibustion:Migraine(WFAS 007.9-2023)is a clinical practice guideline officially released by the World Federation of Acupuncture-Moxibustion Societies(WFAS)on October 9,2023,and is the first international guideline on the treatment of migraine with *** international standard was developed under the guidance of rigorous evidence-based methodology,and it contains guideline purpose,scope,applicable population,applicable settings,overview of acupuncture for migraine,guideline development process and *** promoting the understanding and application of this guideline,this article summarizes a total of 18 recommendations in order to assist clinical decisions for migraine with acupuncture.

关键词： Acupuncture acupuncture Moxibustion

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HiFAST:An H?data calibration and imaging pipeline for FAST

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Science China(Physics,Mechanics & Astronomy) 2024年第5期Mechanics & Astronomy) .卷 186-203页

作者： Yingjie Jing jie wang Chen Xu Ziming Liu Qingze Chen Tiantian Liang Jinlong Xu Yixian Cao Jing wang Huijie Hu Chuan-Peng Zhang Qi Guo Liang Gao Mei Ai Hengqian Gan Xuyang Gao Jinlin Han Ligang Hou Zhipeng Hou Peng Jiang Xu Kong Fujia Li Zerui Liu Li Shao Hengxing Pan Jun Pan Lei Qian Jinghai Sun Ningyu Tang Qingliang Yang Bo Zhang Zhiyu Zhang Ming Zhu National Astronomical Observatories Chinese Academy of Sciences Institute for Frontiers in Astronomy and Astrophysics Beijing Normal University School of Astronomy and Space Science University of Chinese Academy of Sciences Guizhou Radio Astronomical Observatory Guizhou University Max Planck Institute for Extraterrestrial Physics Kavli Institute for Astronomy and Astrophysics Peking University Institute of Computational Cosmology Department of PhysicsUniversity of Durham CAS Key Laboratory of FAST National Astronomical ObservatoriesChinese Academy of Sciences Deep Space Exploration Laboratory/Department of Astronomy University of Science and Technology of China School of Astronomy and Space Science University of Science and Technology of China Astrophysics Department of PhysicsUniversity of Oxford College of Earth Sciences Guilin University of Technology Department of Physics Anhui Normal University School of Astronomy and Space Science Nanjing University Key Laboratory of Modern Astronomy and Astrophysics Nanjing University

The Five-hundred-meter Aperture Spherical radio Telescope（FAST） has the largest aperture and a 19-beam L-band receiver,making it powerful for investigating the neutral hydrogen atomic gas（H?） in the *** present HiFAST（https://***）,a dedicated,modular,and self-contained calibration and imaging pipeline for processing the H?data of *** pipeline consists of frequency-dependent noise diode calibration,baseline fitting,standing wave removal using an FFT-based method,flux density calibration,stray radiation correction,and gridding to produce data *** modules can be combined as needed to process the data from most FAST observation modes:tracking,drift scanning,On-The-Fly mapping,and most of their *** HiFAST,the root-mean-square（RMS） noises of the calibrated spectra from all 19 beams were only slightly（～5%） higher than the theoretical *** results for the extended source M33 and the point sources are consistent with the results from *** moment maps（0,1 and 2） of M33 agree well with the results from the Arecibo Galaxy Environment Survey（AGES） with a fractional difference of less than 10%.For a common sample of 221 sources with signal-to-noise ratio S/N>10 from the Arecibo Legacy Fast ALFA（ALFALFA） survey,the mean value of fractional difference in the integrated flux density,Sint,between the two datasets is approximately 0.005%,with a dispersion of 15.4%.Further checks on the integrated flux density of 23 sources with seven observations indicate that the variance in the flux density of the source with luminous objects(Sint>2.5 Jy km s-1) is less than 5%.Our tests suggest that the FAST telescope,with the efficient,precise,and user-friendly pipeline HiFAST,will yield numerous significant scientific findings in the investigation of the H? in the universe.

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PRB颗粒填料对Cd^(2+)的吸附特征及其孔隙结构动态演变规律

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中南大学学报（自然科学版） 2024年第7期55卷 2504-2515页

作者：江杰王树飞罗豪豪苏建曹斐姝廖长君陈俊霖广西大学土木建筑工程学院广西南宁530004 广西博世科环保科技股份有限公司广西南宁530001 自然资源部南方石山地区矿山地质环境修复工程技术创新中心广西南宁530028

以PRB复合颗粒填料(CGF)开展动态吸附试验,探究其对Cd^(2+)的动态吸附规律与主要影响因素;借助可视化手段与孔隙网络模型(PNM),探究吸附前后CGF的几何特征与孔隙结构演变规律,明确填料消蚀与孔隙堵塞的动态平衡关系。研究结果表明:当泵... 详细信息

以PRB复合颗粒填料(CGF)开展动态吸附试验,探究其对Cd^(2+)的动态吸附规律与主要影响因素;借助可视化手段与孔隙网络模型(PNM),探究吸附前后CGF的几何特征与孔隙结构演变规律,明确填料消蚀与孔隙堵塞的动态平衡关系。研究结果表明:当泵速为10 r/min、质量浓度为50 mg/L时CGF的平衡吸附量最大,达到了1.81 mg/g;泵速对穿透曲线的影响最大,且低流量更有利于CGF对Cd^(2+)的吸附。吸附后孔隙率提高了7.79%,分形维数最多下降了7.95%,孔隙堵塞对分形维数影响较大;CGF溶蚀降低了表面积与平均等效直径,但球度在1.4~1.6范围的颗粒占比提高到75.9%。吸附后平均配位数由10.43降低至8.65,降低了17.07%;同时参与配位的“棍体”与“球体”数量分别降低了43.28%与31.63%。CGF消蚀导致动态柱中部发生堵塞,降低了孔隙与喉道的连接,但并未出现“实质性”堵塞,PNM仍保持良好的连通性能。

关键词：可渗透反应墙(PRB) 动态吸附填料消蚀孔隙堵塞最大球算法

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电裂解芯片及其在细菌核酸分析中的应用

分析测试学报 2024年第3期43卷 373-381页

作者：程洁蔡霜霜王其友陈缵光童艳丽中山大学药学院广东广州510006 南方医科大学附属第三医院广东广州510500 广东省第二人民医院广东广州510310

近年来,由于各种细菌引起的疾病不断爆发,细菌核酸检测已成为常用的实验室诊断方法。细菌核酸提取是细菌分类和鉴定的关键步骤,也是医学诊断、药物筛选的重要技术之一。目前的细菌核酸提取以化学裂解方法为主,其存在明显的缺点,如样品... 详细信息

近年来,由于各种细菌引起的疾病不断爆发,细菌核酸检测已成为常用的实验室诊断方法。细菌核酸提取是细菌分类和鉴定的关键步骤,也是医学诊断、药物筛选的重要技术之一。目前的细菌核酸提取以化学裂解方法为主,其存在明显的缺点,如样品量大、化学试剂污染等。因此,研究快速、简单、无化学污染的检测装置具有重要意义。该研究设计了一种微流控芯片在直流电场下裂解各种细菌并提取核酸。研究了电场强度、电极间距、裂解时间、氧化铟锡电极方阻及电极宽度对核酸提取的影响。结果表明,在3.0 kV/mm的电场强度下,该芯片可在3 s内裂解大肠杆菌、金黄色葡萄球菌、表皮葡萄球菌、枯草芽孢杆菌、肺炎克雷伯氏菌、鼠伤寒沙门氏菌和铜绿假单胞菌等多种细菌,并释放出核酸。提取的核酸无需纯化,可直接用于PCR检测。该芯片与实时荧光定量PCR联用检测细菌DNA的线性范围为10-18~10^(-10)mol/L,检出限低至4.2×10^(-18)mol/L。不同类型的细菌需根据其性质适当调整最佳裂解条件。该研究为病原体分析和细菌感染的医学诊断提供了一种简单、快速、高效且无化学试剂污染的核酸提取方法。

关键词：微流控芯片电裂解核酸提取直流电场多种细菌