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Technical and economic analysis of Ni-containing hot metal production with laterite in blast furnaces

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Baosteel Technical Research 2012年第2期6卷 27-31页

作者： ZHANG Youping CHU bin chen Yan chen Xiangming MA Teng Ironmaking and Sustainability Division Research InstituteBaoshan Iron&Steel Co.Ltd.Shanghai 201900China Stainless Steel Business Unit Baoshan Iron&Steel Co.Ltd.Shanghai 200431China Alloy Developing and Trading Department Baosteel Resources Co.Ltd.Shanghai 200122China

In recent years, many Ni-containing materials manufactured from laterite have played a significant role in supporting the rapid development of the stainless steel industry in China. Currently ,pyrometallurgy is the main process for laterite smelting, where blast furnaces are employed to make Ni-containing hot metal. With the aim of giving some references for making good use of laterite, technical and economic analysis was conducted in this paper, based on the discussion of the key technologies of Ni-containing hot metal production with laterite （50.4% Fe） in blast furnaces.

关键词： latefite blast furnace Ni-containing hot metal technology and economy

Optimization of magnetic resonance sequences in lymph node staging of nasopharyngeal carcinoma

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Chinese Medical Journal 2010年第4期000卷 443-446页

作者： chen Yun-bin HU Chun-miao PAN Jian-ji MAO Yu WEI Wei Department of Radiology Fujian Medical University Teaching Hospital Fujian Provincial Tumor Hospital Fuzhou Fujian 350014 China Department of Radiotherapy Fujian Medical University Teaching Hospital Fujian Provincial Tumor Hospital Fuzhou Fujian 350014 China

Background Detection rate of retropharyngeal lymph node metastasis in patients with nasopharyngeal carcinoma （NPC） needs to be improved. The purpose of this study was to compare three magnetic resonance （MR） sequences for detecting lymph nodes in patients with NPC. Methods Between July 2007 and March 2008, MR staging of pre-treated tumor was conducted on 120 patients with pathologically confirmed NPC. The outcome of three different sequences for MR NPC staging were compared： coronal short T1 inversion recovery （STIR）, axial proton density fat-suppressed （PDWI fs）, and coronal contrast enhanced fast spin echo T1 weighted fat-suppressed （CE FSE TlWl fs）. Nodal classification method （1999） was applied to count the number of retropharyngeal and cervical lymph nodes discovered by each MR sequence. Paired t tests were used for statistical analysis. Results A total of 2575 lymph nodes were found using coronal STIR sequence; 1816 lymph nodes for coronal CE FSE TIWI fs sequence and 2638 lymph nodes for axial PDWl fs sequence. Significant differences existed in the number of lymph nodes detected by axial PDWI fs and coronal CE FSE T1WI fs sequence （paired t test, P 〈0.05）, with the former sequence getting higher numbers. Statistical differences also existed between coronal STIR and coronal CE FSE TlWl fs sequence （paired ttest, P 〈0.05）, with the former sequence getting higher numbers. No significant difference was found between coronal STIR sequence and axial PDWI fs sequence （paired ttest, P 〉0.05）. Conclusions For the detection of retropharyngeal and cervical lymph nodes, coronal STIR sequence and axial PDWI fs sequence have similar performance and both sequences showed better detection than CE FSE TIWI fs sequence. Furthermore, by combining coronal STIR sequence and axial PDWI fs sequence, we can improve the detection of lymph nodes in NPC N-staging before treatment, especially for lymph nodes located in the thoracic entrance.

关键词： nasopharyngeal carcinoma neoplasm staging short TI inversion-recovery proton density weighted image magnetic resonance imaging sequence

Cancer cell employs a microenvironmental neural signal transactivating nucleus-mitochondria coordination to acquire stemness

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Signal Transduction and Targeted Therapy 2023年第8期8卷 3818-3836页

作者： bin He Rui Gao Shasha Lv Ailin chen Junxiu Huang Luoxuan Wang Yunxiu Feng Jiesi Feng bing Liu Jie Lei bing Deng bin He Bai Cui Fei Peng Min Yan Zifeng Wang Eric W-F Lam Bilian Jin Zhiming Shao Yulong Li Jianwei Jiao Xi Wang Quentin Liu State Key Laboratory of Oncology in South China Sun Yat-sen University Cancer CenterGuangzhou 510060PR China Department of Medical Oncology The Seventh Affiliated HospitalSun Yat-sen UniversityShenzhen 510275PR China Institute of Cancer Stem Cell Cancer CenterDalian Medical UniversityDalian 116023PR China Zhongshan School of Medicine Sun Yat-sen UniversityGuangzhou 510080PR China State Key Laboratory of Membrane Biology Peking University School of Life SciencesBeijing 100871PR China Department of Surgery and Cancer Imperial College LondonLondon W120NNUK Department of Breast Surgery Precision Cancer Medicine CenterFudan University Shanghai Cancer CenterShanghai 200032PR China State Key Laboratory of Stem Cell and Reproductive Biology Institute of ZoologyChinese Academy of SciencesBeijing 100101PR China

Cancer cell receives extracellular signal inputs to obtain a stem-like status,yet how tumor microenvironmental(TME)neural signals steer cancer stemness to establish the hierarchical tumor architectures remains ***,a pan-cancer transcriptomic screening for 10852 samples of 33 TCGA cancer types reveals that cAMP-responsive element(CRE)transcription factors are convergent activators for cancer *** of transcriptomic profiles,specification of neural markers and illustration of norepinephrine dynamics uncover a bond between TME neural signals and cancer-cell CRE ***,neural signal norepinephrine potentiates the stemness of proximal cancer cells by activating cAMP-CRE axis,where ATF1 serves as a conserved *** activation by norepinephrine,ATF1 potentiates cancer stemness by coordinated trans-activation of both nuclear pluripotency factors MYC/NANOG and mitochondrial biogenesis regulators NRF1/TFAM,thereby orchestrating nuclear reprograming and mitochondrial ***,single-cell transcriptomes confirm the coordinated activation of nuclear pluripotency with mitochondrial biogenesis in cancer stem-like *** findings elucidate that cancer cell acquires stemness via a norepinephrine-ATF1 driven nucleus-mitochondria collaborated program,suggesting a spatialized stemness acquisition by hijacking microenvironmental neural signals.

关键词： Cancer neural architectures

利用非线性高斯-赫尔默特模型与抗差估计的点云拟合方法

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武汉大学学报（信息科学版） 2024年第7期49卷 1201-1211页

作者：赵志胜陈宇王彬南京工业大学测绘科学与技术学院江苏南京211816

目前已有的点云拟合方法大多是在线性的高斯-马尔可夫(Gauss-Markov,GM)或变量误差(errors-in-variables,EIV)模型基础上提出的,无法严格适用于非线性的曲面拟合问题。将点云拟合的数学模型统一抽象为更具一般性的非线性高斯-赫尔默特(G... 详细信息

目前已有的点云拟合方法大多是在线性的高斯-马尔可夫(Gauss-Markov,GM)或变量误差(errors-in-variables,EIV)模型基础上提出的,无法严格适用于非线性的曲面拟合问题。将点云拟合的数学模型统一抽象为更具一般性的非线性高斯-赫尔默特(Gauss-Helmert,GH)模型,并针对数据存在粗差的情况,引入等价权抗差方案,提出了一种基于抗差非线性GH(robust nonlinear GH,RGH)模型的点云拟合方法。该方法首先从原始观测值的误差出发,将导出的点坐标的协方差阵作为先验随机模型,然后利用标准化残差和中位数构造权函数,进行抗差迭代计算。结果表明,当数据包含粗差时,RGH模型获得的球面仿真数据的参数均方根误差分别仅为随机抽样一致性(random sample consensus,RANSAC)算法的25.77%~30.67%,实测数据的参数标准差分别仅为RANSAC方法的4.63%~5.49%,验证了所提方法在点云拟合的精度和稳健性方面具有显著优势。

关键词：点云拟合粗差非线性GH模型抗差估计标准化残差

Autogenous tibial strut grafts used in severe kyphoscoliosis: surgical policies and preliminary results

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Chinese Medical Journal 2005年第15期118卷 1245-1250页

作者： chen Hui QIU Yong WANG bin YU Yang ZHU Ze-zhang ZHU Li-hua Department of Spine Gulou Hospital Nanjing University Medical School Nanjing 210008 China

Background Surgery for severe kyphoscoliosis is frequently unsatisfying because of loss of correction, high rate of pseudarthrosis and neurological complications. Several authors reported that the anterior fusion with strut grafts might improve the surgical outcome. This article describes and assesses the surgical strategies and the application of autogenous tibial strut in the treatment of severe kyphoscoliosis. Methods Severe kyphoscoliosis patients （n = 39 ） admitted from April 1998 to September 2003 formed the study group. Different surgical strategies had been used according to the flexibility, neurological function and curve level. All patients received staged anterior and posterior surgery with a tibial strut used in the anterior fusion. The patients were followed up for 9 months to 6 years （ mean 37 months）. Results The mean preoperative and postoperative kyphosis was 82° and 52° respectively, and the mean seoliosis was 84° and 44° respectively. Complications included pseudarthrosis （2 eases, one with graft fracture and the other with hook displacement） , posterior elements fractures （4） , pleura penetrations （3, in the plastic surgery of the thoracic cage） , dura tear （2） , exudative pleuritis （2, in the anterior surgery） , and tibia fracture of the harvesting site （ 1 ）. The mean loss of correction in coronal and sagittal plane was 6° and 7° respectively. Except for 1 ease, the patients with incomplete paraplegia showed improvements to varying extents. Conclusion Autogenous tibial strut can provide excellent support to the kyphoscoliotic spine： it reduces pseudarthrodic rate, loss of correction and complications of graft harvest, it also prevents the occurrence of neurological impairment.

关键词： kyphoscoliosis tibial strut autogenous

Stimuli-responsive polymeric nanomaterials for rheumatoid arthritis therapy

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Biophysics Reports 2020年第5期6卷 193-210页

作者： Yingsi Xie Ruslan G.Tuguntaev Cong Mao Haoting chen Ying Tao Shixiang Wang bin Yang Weisheng Guo Translational Medicine Center Key Laboratory of Molecular Target & Clinical Pharmacology School of Pharmaceutical Sciences & the Second Affiliated Hospital Guangzhou Medical University Université Paris 13 99 avenue Jean Baptiste Clément Department of cardiovascular medicine the Third Affiliated Hospital Guangzhou Medical University The Sixth Affiliated Hospital Department of Biomedical Engineering School of Basic Medical Sciences Guangzhou Medical University

Rheumatoid arthritis(RA) is a long-term inflammatory disease derived from an autoimmune disorder of the synovial membrane. Current therapeutic strategies for RA mainly aim to hamper the macrophages’ proliferation and reduce the production of pro-inflammatory cytokines. Therefore, the accumulation of therapeutic agents targeted at the inflammatory site should be a crucial therapeutic strategy. Nowadays, the nanocarrier system incorporated with stimuli-responsive property is being intensively studied, showing the potentially tremendous value of specific therapy. Stimuli-responsive(i.e., p H, temperature, light, redox, and enzyme) polymeric nanomaterials, as an important component of nanoparticulate carriers, have been intensively developed for various diseases treatment. A survey of the literature suggests that the use of targeted nanocarriers to deliver therapeutic agents(nanotherapeutics) in the treatment of inflammatory arthritis remains largely unexplored. The lack of suitable stimuli-sensitive polymeric nanomaterials is one of the limitations. Herein, we provide an overview of drug delivery systems prepared from commonly used stimuli-sensitive polymeric nanomaterials and some inorganic agents that have potential in the treatment of RA. The current situation and challenges are also discussed to stimulate a novel thinking about the development of nanomedicine.

关键词： Rheumatoid arthritis Nanotechnology Stimuli-responsive polymers Drug delivery systems

中低品位贵州铝土矿石灰拜尔法溶出赤泥的沉降分离

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中南大学学报（自然科学版） 2014年第4期45卷 1028-1033页

作者：陈滨肖利唐娴敏湖南工业大学冶金工程学院湖南株洲412011

采用铝硅比为5．48的贵州中低品位一水硬铝石型铝土矿进行石灰拜尔法溶出实验，对溶出后赤泥浆液的沉降分离性能进行实验研究，探讨稀释矿浆脱硅时间、稀释矿浆质量浓度和絮凝剂等因素对赤泥浆液沉降分离过程的影响。实验结果表明：贵... 详细信息

采用铝硅比为5．48的贵州中低品位一水硬铝石型铝土矿进行石灰拜尔法溶出实验，对溶出后赤泥浆液的沉降分离性能进行实验研究，探讨稀释矿浆脱硅时间、稀释矿浆质量浓度和絮凝剂等因素对赤泥浆液沉降分离过程的影响。实验结果表明：贵州铝土矿经石灰拜尔法高压溶出、稀释后，当控制溶液氧化铝质量浓度为165g／L左右，赤泥沉降分离料浆固含约为85g／L时，适宜的脱硅时间为2～3h。稀释脱硅后，赤泥浆液添加絮凝剂CM180进行沉降分离效果较好，当其添加量为210g／t时，5min和10min平均沉降速度分别达19．0和12．1mm／min，30min压缩液固比可达5．29。

关键词：一水硬铝石中低品位铝土矿石灰拜尔法赤泥沉降分离絮凝剂

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等离子体改性聚酰亚胺热老化的分子模拟

原子与分子物理学报 2025年第1期42卷 95-100页

作者：丁璨田浩博陈琛三峡大学电气与新能源学院宜昌443002

通过反应分子动力学方法模拟聚酰亚胺的热老化过程,以模拟仿真等离子体改性后的聚酰亚胺材料在热裂解后的性能变化情况.通过研究老化过程中气体产生的情况,研究发现随着温度升高,分子链之间的相互作用力减弱,导致材料的致密性下降,弹性... 详细信息

通过反应分子动力学方法模拟聚酰亚胺的热老化过程,以模拟仿真等离子体改性后的聚酰亚胺材料在热裂解后的性能变化情况.通过研究老化过程中气体产生的情况,研究发现随着温度升高,分子链之间的相互作用力减弱,导致材料的致密性下降,弹性模量降低,材料抵抗外应力的能力减弱.同时,由于温度升高使得聚酰亚胺材料相对介电常数上升,材料绝缘性能下降,击穿强度也被削弱.

关键词：反应分子动力学聚酰亚胺热老化

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中低品位贵州铝土矿石灰拜尔法溶出工艺

中南大学学报（自然科学版） 2014年第5期45卷 1397-1402页

作者：陈滨肖利唐娴敏湖南工业大学冶金工程学院湖南株洲412011

采用铝硅比为5.48的贵州中低品位一水硬铝石型铝土矿进行石灰拜尔法溶出实验,系统地研究石灰添加量、母液苛碱质量浓度和溶出温度等因素对溶出过程的影响。研究结果表明:随着石灰添加量的增大,溶出赤泥铝硅比和钠硅比均呈明显的下降趋势... 详细信息

采用铝硅比为5.48的贵州中低品位一水硬铝石型铝土矿进行石灰拜尔法溶出实验,系统地研究石灰添加量、母液苛碱质量浓度和溶出温度等因素对溶出过程的影响。研究结果表明:随着石灰添加量的增大,溶出赤泥铝硅比和钠硅比均呈明显的下降趋势,增大石灰添加量对降低碱耗效果十分明显。贵州中低品位铝土矿石灰拜尔法适宜的溶出条件如下:石灰添加量为10%,配料分子比为1.45,循环母液苛碱质量浓度为200 g/L左右,溶出温度为270℃左右,溶出时间50 min,在此溶出条件下,溶出液苛性比95%。

关键词：一水硬铝石中低品位铝土矿石灰拜尔法溶出