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Applying Logic Programming to Knowledge Discovery on the Internet

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Wuhan University Journal of Natural Sciences 2001年第Z1期6卷 320-325页

作者： Cheng Xi,Feng Gang,Hou yin bin Institute of Computer Information and Technology , Xi’an Jiaotong University, Xi’an 710049, China Institute of Computer Information and Technology Xi’an Jiaotong University Xi’an China

LP (Logic Programming) has been successfully applied to knowledge discovery in many fields. The execution of the LP is based on the evaluation of the first order predicate. Usually the information involved in the predicates are local and homogenous, thus the evaluation process is relatively simple. However, the evaluation process become much more complicated when applied to KDD on the Internet where the information involved in the predicates maybe heterogeneous and distributed over many different sits. Therefor, we try to attack the problem in a multi agent system's framework so that the logic program can be written in a site independent style and deal easily with heterogeneous represented information.

关键词： logic programming knowledge discovery internet

Max-Min Adaptive Ant Colony Optimization Approach to Multi-UAVs Coordinated Trajectory Replanning in Dynamic and Uncertain Environments

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Journal of Bionic Engineering 2009年第2期6卷 161-173页

作者： Hai-bin Duan,Xiang-yin Zhang,Jiang Wu,Guan-jun MaSchool of Automation Science and Electrical Engineering,Beihang University,Beijing 100191,P.R.China [a]School of Automation Science and Electrical Engineering Beihang University Beijing 100191 P. R. China

Multiple Uninhabited Aerial Vehicles (multi-UAVs) coordinated trajectory replanning is one of the most complicated global optimum problems in multi-UAVs coordinated control. Based on the construction of the basic model of multi-UAVs coordinated trajectory replanning, which includes problem description, threat modeling, constraint conditions, coordinated function and coordination mechanism, a novel Max-Min adaptive Ant Colony Optimization (ACO) approach is presented in detail. In view of the characteristics of multi-UAVs coordinated trajectory replanning in dynamic and uncertain environments, the minimum and maximum pheromone trails in ACO are set to enhance the searching capability, and the point pheromone is adopted to achieve the collision avoidance between UAVs at the trajectory planner layer. Considering the simultaneous arrival and the air-space collision avoidance, an Estimated Time of Arrival (ETA) is decided first. Then the trajectory and flight velocity of each UAV are determined. Simulation experiments are performed under the complicated combating environment containing some static threats and popup threats. The results demonstrate the feasibility and the effectiveness of the proposed approach.

关键词： Multiple Uninhabited Aerial Vehicles (multi-UAVs) Ant Colony Optimization (ACO) trajectory replanning collision avoidance Estimated Time of Arrival (ETA)

Effects of bilateral subthalamic nucleus deep brain stimulation on motor symptoms in Parkinson’s disease: a retrospective cohort study

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Neural Regeneration Research 2021年第5期16卷 905-909页

作者： Guo-Xiong Cheng Shu-bin yin ying-Hao Yang Yuan-Hu Hu Chih-Yang Huang Qian-Ming Yao Wei-Jen Ting Deparment of Neurosurgery The First Affiliated Hospital of Guangzhou Medical UniversityGuangzhouGuangdong ProvinceChina Deparment of Neurosurgery The Sixth Affiliated Hospital of Guangzhou Medical UniversityQingyuanGuangdong ProvinceChina Graduate Institute of Basic Medical Science China Medical UniversityTaichungTaiwanChina Department of Health and Nutrition Biotechnology Asia UniversityTaichungTaiwanChina College of Medicine Hualien Tzu Chi HospitalBuddhist Tzu Chi Medical FoundationTzu Chi UniversityHualienTaiwanChina Medical Research Center for Exosome and Mitochondria Related Diseases China Medical University and HospitalTaichungTaiwanChina

Deep brain stimulation of the bilateral subthalamic nucleus(STN)is a therapeutic option for patients with Parkinson’s disease(PD)in whom medical therapies have been *** retrospective cohort study analyzed the motor function of 27 patients with advanced PD,from the First Affiliated Hospital of Guangzhou Medical University,China,who received deep brain stimulation of the bilateral subthalamic nucleus and evaluated its therapeutic *** 10-year follow-up data of patients was analyzed in Qingyuan People’s Hospital,Sixth Affiliated Hospital of Guangzhou Medical University,*** follow-up data were divided into two categories based on patients during levodopa treatment(on-medication)and without levodopa treatment(off-medication).Compared with baseline,the motor function of onmedication PD patients improved after deep brain stimulation of the bilateral subthalamic *** 2 years later,the motor function of off-medication PD patients had ***-medication PD patients exhibited better therapeutic effects over the 5 years than offmedication PD ***-medication patients’akinesia,speech,postural stability,gait,and cognitive function worsened only after 5 *** results suggest that the motor function of patients with advanced PD benefitted from treatment with deep brain stimulation of the bilateral subthalamic nucleus over a period up to 5 *** overall therapeutic effects were more pronounced when levodopa treatment was combined with deep brain stimulation of the bilateral subthalamic *** study was approved by Institutional Review Board of Qingyuan People’s Hospital,The Sixth Affiliated Hospital of Guangzhou Medical University,China(approval ***-IRB-A0140)on January 11,2018.

关键词： clinical trial deep brain stimulation dopamine dyskinesia levodopa long-term follow-up neurological function Parkinson’s disease thalamus UPDRS

Docking protein 6 (DOK6) selectively docks the neurotrophic signaling transduction to restrain peripheral neuropathy

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Signal Transduction and Targeted Therapy 2024年第3期9卷 1147-1164页

作者： Yan Guo Pan Xiang Xiaojiao Sun Wei Liu Jiafeng Zhou bin yin Lin Hou Boqin Qiang Huiliang Li Pengcheng Shu Xiaozhong Peng Department of Molecular Biology and Biochemistry Institute of Basic Medical SciencesMedical Primate Research CenterNeuroscience CenterChinese Academy of Medical SciencesSchool of Basic Medicine Peking Union Medical CollegeBeijingChina State Key Laboratory of Common Mechanism Research for Major Diseases Beijing 100005China Wolfson Institute for Biomedical Research University College LondonGower StreetLondon WC1E 6BTUK Chinese Institute for Brain Research Beijing 102206China State Key Laboratory of Respiratory Health and Multimorbidity Beijing 100005China Institute of Laboratory Animal Science Chinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100021China

The appropriate and specific response of nerve cells to various external cues is essential for the establishment and maintenance of neural circuits,and this process requires the proper recruitment of adaptor molecules to selectively activate downstream ***,we identified that DOK6,a member of the Dok(downstream of tyrosine kinases)family,is required for the maintenance of peripheral axons,and that loss of Dok6 can cause typical peripheral neuropathy symptoms in mice,manifested as impaired sensory,abnormal posture,paw deformities,blocked nerve conduction,and ***,Dok6 is highly expressed in peripheral neurons but not in Schwann cells,and genetic deletion of Dok6 in peripheral neurons led to typical peripheral myelin outfolding,axon destruction,and hindered retrograde axonal ***,DOK6 acts as an adaptor protein for selectivitymediated neurotrophic signal transduction and retrograde transport for TrkC and Ret but not for TrkA and ***6 interacts with certain proteins in the trafficking machinery and controls their phosphorylation,including MAP1B,Tau and Dynein for axonal transport,and specifically activates the downstream ERK1/2 kinase pathway to maintain axonal survival and *** finding provides new clues to potential insights into the pathogenesis and treatment of hereditary peripheral neuropathies and other degenerative diseases.

关键词： impaired restrain peripheral

Optimizing Nitrogen Fertilizer Application for Rice Production in the Taihu Lake Region,China

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Pedosphere 2012年第1期22卷 48-57页

作者： DENG Mei-Hua SHI Xiao-Jun TIAN Yu-Hua yin bin ZHANG Shao-Lin ZHU Zhao-Liang S.D.KIMURA State Key Laboratory of Soil and Sustainable Agriculture Institute of Soil ScienceChinese Academy of SciencesNanjing 210008(China) College of Resources and Environments Southwest UniversityChongqing 310047(China) United Graduate School of Agriculture Science Tokyo University of Agriculture and TechnologyTokyo 1838509(Japan)

To determine the optimal amount of nitrogen(N) fertilizer for achieving a sustainable rice production at the Taihu Lake region of China,two-year on-farm field experiments were performed at four sites using various N application *** results showed that 22%-30% of the applied N was recovered in crop and 7%-31% in soils at the rates of 100-350 kg N ha *** losses increased with N application rates,from 44% of the applied fertilizer N at the rate of 100 kg N ha 1 to 69% of the N applied at 350 kg N ha *** volatilization and apparent denitrification were the main pathways of N *** N application rate of 300 kg N ha 1,which is commonly used by local farmers in the study region,was found to lead to a significant reduction in economic and environmental *** the cost for mitigating environmental pollution and the maximum net economic income,an application rate of 100-150 kg N ha 1 would be *** recommended N application rate could greatly reduce N loss from 199 kg N ha 1 occurring at the N application rate of 300 kg N ha 1 to 80-110 kg N ha 1,with the rice grain yield still reaching 7 300-8 300 kg DW ha 1 in the meantime.

关键词： economic efficiency environmental efficiency N application rate N loss rice grain yield

Architecture and key technologies of grid geographic information system

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Science China(Technological Sciences) 2008年第S1期51卷 102-113页

作者： FANG Yu,HUANG Zhou,CHEN bin,WU Lun & yin DaFei Institute of Remote Sensing and Geographic Information System,Peking University,Beijing 100871,China Institute of Remote Sensing and Geographic Information System Peking University Beijing 100871 China

The highly efficient and stable collaborative computation platform for geospatial information can be constructed on the basis of Grid computing technology,com-bined with Peer-to-Peer (P2P) computing technology and geospatial database technology. This paper proposed the architecture and key technologies of the Grid GIS (Geographic Information System) incorporated with P2P structure,and corre-spondingly a Grid GIS prototype named Nebula was designed and then imple-mented. Nebula is a suite of middleware for geospatial Grid computing,which could be deployed onto various service nodes in network. Based on Grid protocols and infrastructure,Nebula provides invocation interfaces to users in form of Grid services. By using P2P message based communication mechanism,complex geospatial computation tasks could be accomplished by Nebula in a collaborative way. This paper introduced Nebula's architecture and key modules,and according to experimental data,we discussed the Grid GIS's advantages,application scenar-ios and future directions.

关键词： Grid GIS distributed geospatial computing Peer-to-Peer computing

The Tragic Flavors in The Merchant of Venice

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Sino-US English Teaching 2013年第2期10卷 162-167页

作者： LI Bao-feng yin bin Harbin Engineering University Harbin China

The Merchant of Venice （1914）, as one of the greatest works by Shakespeare, is a comedy. It addresses various themes. It is much more than a study of the struggles between Christians and Jews; it also deals with love and self-sacrifice, hatred and revenge, and friendship and marriage. It is a victory of Christians against Jews. But, at a more profound level, the play is ultimately a tragedy which functions as a cautionary exposure on the social problems of prejudice, hypocrisy and the family relationships. The paper begins by addressing the prejudice that is a dominant theme throughout the play. It also contends that the hypocrisy is prevalent in Venetian society. Then, Shylock, as the tragic hero in the play is analyzed. The final part deals with the problem of family relationships. By exposing grave deficiencies in Venetian Society, the play obliges us to make a critical moral judgment on humanity and establish correct philosophy of life and values

关键词： tragic flavors prejudice hypocrisy family relationships

Current Situation and Protection Measures concerning the Wetland Resources in Yunnan Province

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Asian Agricultural Research 2016年第7期8卷 75-77,83页

作者： bin yin Yong ZHENG School of Tourism and Geographical Sciences Yunnan Normal University School of Life Sciences Yunnan Normal University

Yunnan has various and rich wetland resources because of the special geographical environment. In recent years,Yunnan has made great achievement in the management,protection and development of the wetland resources,but many problems still exist. Based on the threats,this paper puts forward the protection and use measures for the wetland resources in Yunnan by analyzing and studying the wetland resources as well as types and basic features.

关键词： Wetland types Wetland resources Threat Protection measures

Cloning and prokaryotic expression of HGLP cDNA

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Chinese Science Bulletin 2001年第13期46卷 1089-1092页

作者： ZHOU Haijun HUANG Xiaowei ZHOU Yan LI Guangtao yin bin MA Yanling PENG Xiaozhong YUAN Jiangang QIANG Boqin Institute of Basic Medical Sciences Chinese Academy of Medical Sciences&Peking Union Medical CollegeNational Center of Human Genome ResearchBeijing 100005China

A novel cDNA, HGLP, which encodes a G-protein coupled receptor (GPCR) like protein, has been isolated and cloned. The coding region of the human HGLP predicts a 7-transmembrane region protein with motifs of rhodopsin-like GPCR superfamily. Northern blot analysis reveals a 3-kb transcript in various human tissues examined. The N- and C-terminal coding regions of HGLP, which are deduced as non-transmembrane regions, have been amplified by PCR and cloned into pET30a+ vector. Then the re-combinant proteins are highly expressed in E. coli.

关键词： G-protein coupled receptor HGLP cDNA prokaryotic expression.