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Laser Cleaning Techniques for Removing Surface Particulate Contaminants on Sol-Gel SiO_(2) Films

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Chinese Physics Letters 2011年第7期28卷 133-136页

作者： ZHANG Chun-Lai LI Xi-bin WANG Zhi-Guo LIU Chun-Ming XIANG Xia LV Hai-bing yuan Xiao-Dong ZU Xiao-Tao School of Physical Electronics University of Electronic Science and Technology of ChinaChengdu 610054 Research Center of Laser Fusion China Academy of Engineering PhysicsMianyang 621900

Dry laser cleaning(DLC)and laser shockwave cleaning(LSC)are used to remove the particulate contamination from SiO_(2) sol−gel optical *** results show that the LSC with a shockwave initiated by plasma formation under a focused laser beam pulse offers much better efficiency than *** particles up to 10µm on SiO_(2 )films can be removed without substrate damage at a gap distance of 0.5 mm,and a more uniform surface microstructure can be obtained after ***,it is demonstrated that the transmittance of contaminated SiO2 films can be restored to the as-deposited value after the LSC on dispersed-particle *** has potential applications in engineering-oriented large components.

关键词： removed remove moving

非晶硅薄膜晶体管中不饱和输出电流的数值仿真

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华南理工大学学报（自然科学版） 2009年第1期37卷 15-18,33页

作者：刘远姚若河李斌华南理工大学电子与信息学院广东广州510640

针对氢化非晶硅薄膜晶体管中的输出电流不饱和现象,采用半导体器件模拟软件对非晶硅薄膜晶体管的输出特性进行了数值仿真,并探讨了不饱和输出电流的产生机理.仿真结果表明:在长沟道器件中,随着漏源电压的增加,体电流的传输机制将转变为... 详细信息

针对氢化非晶硅薄膜晶体管中的输出电流不饱和现象,采用半导体器件模拟软件对非晶硅薄膜晶体管的输出特性进行了数值仿真,并探讨了不饱和输出电流的产生机理.仿真结果表明:在长沟道器件中,随着漏源电压的增加,体电流的传输机制将转变为空间电荷限制传导,此即为器件中产生不饱和输出电流的主要原因;而在短沟道器件中,还需要同时考虑漏致势垒降低效应的影响.

关键词：非晶硅薄膜晶体管不饱和输出电流数值仿真空间电荷限制传导漏致势垒降低

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Evaluation of an extracellular matrix-derived acellular biphasic scaffold/cell construct in the repair of a large articular high-load-bearing osteochondral defect in a canine model

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Chinese Medical Journal 2011年第23期124卷 3930-3938页

作者： YANG Qiang PENG Jiang LU Shi-bi GUO Quan-yi ZHAO bin ZHANG Li WANG Ai-yuan XU Weng-jing XIA Qun MA Xin-long HU Yong-cheng XU Bao-shan Institute of Orthopedics Chinese People＇s Liberation Army General Hospital Beijing 100853 China

Osteochondral lesion repair is a challenging area of orthopedic surgery. Here we aimed to develop an extracellular matrix-derived, integrated, biphasic scaffold and to investigate the regeneration potential of the scaffold loaded with chondrogenically-induced bone marrow-derived mesenchymal stem cells （BMSCs） in the repair of a large, high-load-bearing, osteochondral defect in a canine model. Methods The biphasic scaffolds were fabricated by combining a decellularization procedure with a freeze-drying technique and characterized by scanning electron microscopy （SEM） and micro-computed tomography （micro-CT）. Osteochondral constructs were fabricated in vitro using chondrogenically-induced BMSCs and a biphasic scaffold, then assessed by SEM for cell attachment. Osteochondral defects （4.2 mm （diameter） ×6 mm （depth）） were created in canine femoral condyles and treated with a construct of the biphasic scaffold/chondrogenically-induced BMSCs or with a cell-free scaffold （control group）. The repaired defects were evaluated for gross morphology and by histological, biochemical, biomechanical and micro-CT analyses at 3 and 6 months post-implantation. Results The osteochondral defects of the experimental group showed better repair than those of the control group. Statistical analysis demonstrated that the macroscopic and histologic grading scores of the experimental group were always higher than those of the control group, and that the scores for the experimental group at 6 months were significantly higher than those at 3 months. The cartilage stiffness in the experimental group （6 months） was （6.95±0.79） N/mm, 70.77% of normal cartilage; osteochondral bone stiffness in the experimental group was （158.16±24.30） N/mm, 74.95% of normal tissue; glycosaminoglycan content of tissue-engineered neocartilage was （218±21.6） tJg/mg （dry weight）, 84.82% of native cartilage. Micro-CT analysis of the subchondral bone showed mature trabecular bone regularly formed at 3 and 6 months, with n

关键词： osteochondral tissue engineering extracellular matrix bone marrow-derived mesenchymal stem cell biphasic scaffold micro-computed tomography

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连续激光光腔衰荡法精确测量高反射率

中国激光 2006年第9期33卷 1247-1250页

作者：龚元李斌成中国科学院光电技术研究所

提出了基于宽谱半导体激光器连续激光光腔衰荡法测量高反射率的方法,给出了方波调制连续激光光腔衰荡法理论。采用锁相技术记录光腔输出信号一次谐波的振幅和相位,由振幅和相位随调制频率的变化曲线分别拟合衰荡时间。给出了不同腔长下... 详细信息

提出了基于宽谱半导体激光器连续激光光腔衰荡法测量高反射率的方法,给出了方波调制连续激光光腔衰荡法理论。采用锁相技术记录光腔输出信号一次谐波的振幅和相位,由振幅和相位随调制频率的变化曲线分别拟合衰荡时间。给出了不同腔长下两种拟合方式分别得到的衰荡时间,最终确定腔镜反射率为99.70%,误差小于0.01%。由频域拟合方式得到反射率结果,使可靠性得到提高。与脉冲激光光腔衰荡法相比,采用连续半导体激光器作光源,大大降低了成本,且由于光束质量高,更有利于提高测量精度。

关键词：测量高反射率光腔衰荡宽谱连续激光

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Polymer Electro-optic Modulator Linear Bias Using the Thermo-optic Effect

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Chinese Physics Letters 2012年第1期29卷 152-155页

作者： SUN Xiao-Qiang CHEN Chang-Ming LI Xiao-Dong WANG Xi-bin YANG Tian-Fu ZHANG Da-Ming WANG Fei XIE Zhi-yuan Changchun Institute of Applied Chemistry Chinese Academy of SciencesChangchun 130022 State Key Laboratory on Integrated Optoelectronics Jilin UniversityChangchun 130012

A quasi-rectangular waveguide polymer MacH^(-)Zehnder (M-Z) electro-optic (EO) modulator based on an organic/inorganic hybrid material with thermal bias control is fabricated and *** bias for the modulator is obtained through thermo-optic *** optical output is adjusted by changing phase difference between the two arms of the M-Z interferometer.A power consumption of 16.1 m W for π phase change is observed owing to the application of silica *** approach is proved to be effective to suppress direct current drift in polymer EO modulators.

关键词： modulator interferometer waveguide

Preliminary application of 3D-printed coplanar template for iodine-125 seed implantation therapy in patients with advanced pancreatic cancer

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World Journal of Gastroenterology 2018年第46期24卷 5280-5287页

作者： Wei Huang Jian Lu Ke-Min Chen Zhi-yuan Wu Qing-bin Wang Jing-Jing Liu Ju Gong Zhi-Jin Chen Xiao-Yi Ding Zhong-Min Wang Department of Interventional Radiology Ruijin HospitalShanghai Jiao Tong University School of Medicine Department of Radiology Ruijin Hospital Luwan BranchShanghai Jiao Tong University School of Medicine Department of Radiology Ruijin HospitalShanghai Jiao Tong University School of Medicine

AIM To evaluate a 3 D-printed coplanar template for iodine-125 seed implantation therapy in patients with pancreatic cancer. METHODS A retrospective analysis of our database was performed, and a total of 25 patients with pancreatic cancer who underwent iodine-125 seed implantation between January 2014 and November 2017 were analyzed. Of these, 12 implantations were assisted by a 3 D-printed coplanar template(group A), and 13 implantations performed freehand were selected as a control group(group B). A 3 D coplanar template was designed and printed according to a preoperative CT scan and treatment planning system. The iodine-125 seeds were then implanted using the template as a guide. Dosimetric verification was performed after implantation. Pre-and postoperative D90, V100, and V150 were calculated. The success rate of iodine-125 seed implantation, dosimetric parameters, and complications were analyzed and compared between the two *** Iodine-125 seed implantation was successfully performed in both groups. In group A, the median pre-and postoperative D90 values were 155.32 ± 8.05 Gy and 154.82 ± 16.43 Gy, respectively; the difference between these values was minimal and not statistically significant(P > 0.05). Postoperative V100 and V150 were 91.05% ± 4.06% and 64.54% ± 13.40%, respectively, which met the treatment requirement. A better dosimetric parameter was observed in group A than in group B, and the difference was statistically significant(V100: 91.05% ± 4.06% vs 72.91% ± 13.78%, P < 0.05). No major procedure-related complications were observed in either group. For group A, mild hemorrhage was observed in 1 patient with a peritoneal local hematoma due to mesenteric vein damage from the iodine-125 seed implantation needle. The hematoma resolved spontaneously without treatment. Postoperative blood amylase levels remained within the normal range for all *** A 3 D-printed coplanar template appears to be a safe and effective iodine-125 seed

关键词： 3D printing Brachytherapy Iodine-125 Pancreatic cancer

Coaxial radiography guided puncture technique for percutaneous transforaminal endoscopic lumbar discectomy:A randomized control trial

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World Journal of Clinical Cases 2023年第16期11卷 3802-3812页

作者： Li-Ping Chen bin-Song Wen Heng Xu Zheng Lu Lai-Jun Yan Han Deng Hong-Bo Fu Hong-Jie yuan Pei-Pei Hu Department of Pain Management The Affiliated Hospital of Xuzhou Medical CollegeXuzhou 221000Jiangsu ProvinceChina Department of Pain Management Nantong Hospital of Traditional Chinese MedicineNantong 226000Jiangsu ProvinceChina Department of Neurosurgery Haian People's HospitalNantong 226001Jiangsu ProvinceChina

BACKGROUND The coaxial radiography-guided puncture technique(CR-PT)is a novel technique for endoscopic lumbar *** the X-ray beam and the puncturing needle are maintained in a parallel and coaxial direction,the X-ray beam can be used to guide the trajectory angle,facilitating the choice of the puncture site and providing real-time *** puncture technique offers numerous advantages over the conventional anterior-posterior and lateral radiography-guided puncture technique(AP-PT),especially in cases of herniated lumbar discs with a hypertrophied transverse process or articular process,high iliac crest,and narrowed intervertebral *** To confirm whether CR-PT is a superior approach to percutaneous transforaminal endoscopic lumbar discectomy compared to *** In this parallel,controlled,randomized clinical trial,herniated lumbar disc patients appointed to receive percutaneous endoscopic lumbar discectomy treatment were recruited from the Pain Management Department of the Affiliated Hospital of Xuzhou Medical University and Nantong Hospital of Traditional Chinese ***-five participants were enrolled and divided into either a CR-PT group or an AP-PT *** CR-PT group underwent CR-PT,and the AP-PT group underwent *** number of fluoroscopies during puncturing,puncture duration(min),surgery duration(min),VAS score during puncturing,and puncture success rate were *** Sixty-five participants were included,with 31 participants in the CR-PT group and 34 in the AP-PT *** participant in the AP-PT group dropped out due to unsuccessful *** number of fluoroscopies[median(P25,P75)]was 12(11,14)in the CR-PT group vs 16(12,23)in the AP-PT group,while the puncture duration(mean±SD)was 20.42±5.78 vs 25.06±5.46,*** VAS score was 3(2,4)in the CR-PT group vs 3(3,4)in the AP-PT *** subgroup analysis was performed,considering only the participants with L5/S1 segment herniation:9 patients un

关键词： Herniated lumbar disc Coaxial Puncture Anterior-posterior L5/S1

Continuous glucose monitoring defined time-in-range is associated with sudomotor dysfunction in type 2 diabetes

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World Journal of Diabetes 2020年第11期11卷 489-500页

作者： Qing-Yu Guo bin Lu Zhan-Hong Guo Zhou-Qin Feng Yan-Yu yuan Xu-Guang Jin Pu Zang Ping Gu Jia-Qing Shao Department of Endocrinology Jinling HospitalSchool of MedicineNanjing UniversityNanjing 210002Jiangsu ProvinceChina Department of Endocrinology Jinling HospitalNanjing Medical UniversityNanjing 210002Jiangsu ProvinceChina Department of Endocrinology Jinling HospitalSouthern Medical UniversityNanjing 210002Jiangsu ProvinceChina

BACKGROUND Time in range(TIR),as a novel metric for glycemic control,has robust relevance with diabetic *** peripheral neuropathy(DPN)is characterized by sudomotor *** To explore the relationship between TIR obtained from continuous glucose monitoring(CGM)and sudomotor function detected by SUDOSCAN in subjects with type 2 *** The research enrolled 466 inpatients with type 2 *** subjects underwent 3-d CGM and *** was assessed with electrochemical skin conductance in hands(HESC)and feet(FESC).Average feet ESC<60μS was defined as sudomotor dysfunction(+),otherwise it was sudomotor dysfunction(-).TIR refers to the percentage of time when blood glucose is between 3.9-10 mmol/L during 1 d *** Among the enrolled subjects,135(28.97%)presented with sudomotor *** with sudomotor dysfunction(+)showed a decreased level of TIR(P<0.001).Compared to the lowest tertile of TIR,the middle and the highest tertiles of TIR was associated with an obviously lower prevalence of sudomotor dysfunction(20.51%and 21.94%vs 44.52%)(P<0.001).In addition,with the increase of TIR,HESC and FESC increased(P<0.001).Regression analysis demonstrated that TIR was inversely and independently linked with the prevalence of sudomotor dysfunction after adjusting for confounding values(odds ratio=0.979,95%CI:0.971-0.987,P<0.001).CONCLUSION The tight glycemic control assessed by TIR is of vitally protective value for sudomotor dysfunction in type 2 diabetes mellitus.

关键词： Time in range Sudomotor dysfunction SUDOSCAN Diabetic peripheral neuropathy Continuous glucose monitoring Diabetes mellitus Type 2

浙江省龙游县肺结核诊疗“零负担”策略实施效果评估

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中国防痨杂志 2024年第4期46卷 418-423页

作者：王莉燕周慧吴倩郝晓刚陆冰欣陈彬浙江省龙游县疾病预防控制中心传染病防制科龙游324400 浙江省疾病预防控制中心结核病预防控制所杭州310051 浙江省衢州市疾病预防控制中心艾滋病结核病防制科衢州324000

目的:比较浙江省龙游县肺结核诊疗“零负担”策略实施前后各项肺结核防治指标的变化情况,为制订新时期肺结核防控措施提供科学依据。方法:通过“中国疾病预防控制信息系统”子系统“结核病管理信息系统”收集2016—2022年浙江省衢州市各... 详细信息

目的:比较浙江省龙游县肺结核诊疗“零负担”策略实施前后各项肺结核防治指标的变化情况,为制订新时期肺结核防控措施提供科学依据。方法:通过“中国疾病预防控制信息系统”子系统“结核病管理信息系统”收集2016—2022年浙江省衢州市各县(市、区)和与龙游县接壤县区(包括遂昌县、兰溪市、婺城区、建德市)的肺结核报告发病数据,以及现住址为龙游县的肺结核患者的本县收治率和治疗转归数据;常住人口数来源于当地统计年鉴;龙游县肺结核患者诊疗费用数据来自龙游县人民医院信息管理系统;肺结核患者的中断治疗率、政策满意度调查由定点医院与社区随访医生调查收集。比较龙游县肺结核诊疗“零负担”策略实施前(2016—2018年)和实施后(2020—2022年)肺结核患者诊疗费用、肺结核报告发病率、本县收治率、治疗转归等指标情况,分析该策略的实施效果。结果:肺结核患者个人支付费用总额在“零负担”策略实施前分别为:2016年830322.45元,2017年833450.10元,2018年792879.99元,患者人均自付费用分别为3075.27元、3281.30元、3523.91元。“零负担”策略实施后,普通肺结核患者个人支付费用比例降低到0,县财政兜底费用逐年下降(2020—2022年分别为492160.29、401349.56、389319.42元)。2016年龙游县肺结核报告发病率为74.17/10万(270/36.4万),到2022年降低至47.21/10万(169/35.8万),差异有统计学意义(χ_(趋势)^(2)=43.962,P<0.001);报告肺结核患者本地收治率由2016年的74.81%(202/270)明显提高到2022年的93.49%(158/169),差异有统计学意义(χ_(趋势)^(2)=64.483,P<0.001);报告肺结核患者中断治疗率由2016年的6.30%(17/270)明显降低到2022年的1.18%(2/169),差异有统计学意义(χ_(趋势)^(2)=17.965,P=0.003)。结论:浙江省龙游县肺结核诊疗“零负担”策略的实施降低了肺结核患者医疗负担,提高了肺结核患者本地收治率,降低了患者中断治疗率及总体肺结核报告发病率,策略实施效果初显。

关键词：结核,肺费用,医疗卫生政策评价研究

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