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Solar trough receiver with V-grooved light traps for efficiency improvement

Science China(Technological Sciences) 2025年第1期68卷 142-152页

作者： bin liu Qing LI Yu QIU School of Energy Science and Engineering Central South UniversityChangsha 410083China

Parabolic trough collector is a promising technology for both domestic and industrial heat *** enhance the collector efficiency,a modified trough receiver with dozens of V-grooved light traps incorporated into its lower-half absorber was *** assessing the performance of this receiver,a solar-thermal-stress coupled model was *** this model,firstly,the effects of the V-grooved light traps were *** results reveal that,compared to the conventional trough receiver,the modified trough receivers equipped with different traps can reduce their optical losses by 81.9-138.0 Wm^(-1)(i.e.,15.0%-25.2%),improving their optical efficiencies by 1.60%-2.69%.However,these traps also result in increased thermal loss from the ***,there is no single optimal modified trough receiver that consistently outperforms all other receivers across all possible ***,the MTR30-3 and MTR60-3 receivers emerge as the optimized choices due to their better solar-thermal ***,performance evaluation reveals that the two optimized receivers can enhance the receiver efficiencies within the typical solar irradiance range by 0.02%-2.65%and 0.05%-1.70%when the inlet fluid temperatures are below 488 and 523 K,***,the collector efficiencies can be improved by 0.02%-2.49%and 0.05%-1.60%,***,thermal stress analysis verifies that the two optimized receivers remain within safe limits under all typical *** that the heating temperature of a typical solar collector for domestic or industrial heat supply is typically below 523 K,the integration of the two optimized receivers has the capability to effectively enhance the overall collector efficiency.

关键词： parabolic trough collector receiver V-grooved light trap solar-thermal-stress coupled model efficiency improvement

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Inhibiting ceramide synthase 5 expression in microglia decreases neuroinflammation after spinal cord injury

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Neural Regeneration Research 2025年第10期20卷 2955-2968页

作者： Wei Zhang Yubao Lu Ruoqi Shen Yingjie Wu Chenrui liu Xingxing Fang Liangming Zhang bin liu Limin Rong Department of Spine Surgery The Third Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdong ProvinceChina National Medical Products Administration(NMPA)Key Laboratory for Quality Research and Evaluation of Cell Products GuangzhouGuangdong ProvinceChina Guangdong Provincial Center for Quality Control of Minimally Invasive Spine Surgery GuangzhouGuangdong ProvinceChina Guangdong Provincial Center for Engineering and Technology Research of Minimally Invasive Spine Surgery GuangzhouGuangdong ProvinceChina

Microglia,the resident monocyte of the central nervous system,play a crucial role in the response to spinal cord ***,the precise mechanism remains *** investigate the molecular mechanisms by which microglia regulate the neuroinflammatory response to spinal cord injury,we performed single-cell RNA sequencing dataset analysis,focusing on changes in microglial *** found that the MG1 subpopulation emerged in the acute/subacute phase of spinal cord injury and expressed genes related to cell pyroptosis,sphingomyelin metabolism,and neuroinflammation at high ***,we established a mouse model of contusive injury and performed intrathecal injection of siRNA and molecular inhibitors to validate the role of ceramide synthase 5 in the neuroinflammatory responses and pyroptosis after spinal cord ***,we established a PC12-BV2 cell co-culture system and found that ceramide synthase 5 and pyroptosis-associated proteins were highly expressed to induce the apoptosis of neuron *** ceramide synthase 5 expression in a mouse model of spinal cord injury effectively reduced ***,ceramide synthase 5-induced pyroptosis was dependent on activation of the NLRP3 signaling *** ceramide synthase 5 expression in microglia in vivo reduced neuronal apoptosis and promoted recovery of neurological ***2g7 formed a“bridge”between sphingolipid metabolism and ceramide synthase 5-mediated cell death by inhibiting the NLRP3 signaling ***,these findings suggest that inhibiting ceramide synthase 5 expression in microglia after spinal cord injury effectively suppressed microglial pyroptosis mediated by NLRP3,thereby exerting neuroprotective effects.

关键词： ceramide synthase 5 gasdermin D microglia neuroinflammation NLRP3 nuclear factor kappa B Pla2g7 pyroptosis sphingomyelin metabolism spinal cord injury

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A promising approach for quantifying focal stroke modeling and assessing stroke progression:optical resolution photoacoustic microscopy photothrombosis

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Neural Regeneration Research 2025年第7期20卷 2029-2037页

作者： Xiao Liang Xingping Quan Xiaorui Geng Yujing Huang Yonghua Zhao Lei Xi Zhen Yuan Ping Wang bin liu Faculty of Health Sciences University of MacaoMacao Special Administrative RegionChina Center for Cognitive and Brain Sciences University of MacaoMacao Special Administrative RegionChina Department of Biomedical Engineering Southern University of Science and TechnologyShenzhenGuangdong ProvinceChina State Key Laboratory of Quality Research in Chinese Medicine Institute of Chinese Medical SciencesUniversity of MacaoTaipaMacao Special Administrative RegionChina Department of Emergency Zhujiang HospitalSouthern Medical UniversityGuangzhouGuangdong ProvinceChina

To investigate the mechanisms underlying the onset and progression of ischemic stroke,some methods have been proposed that can simultaneously monitor and create embolisms in the animal cerebral ***,these methods often require complex systems and the effect of age on cerebral embolism has not been adequately studied,although ischemic stroke is strongly *** this study,we propose an optical-resolution photoacoustic microscopy-based visualized photothrombosis methodology to create and monitor ischemic stroke in mice simultaneously using a 532 nm pulsed *** observed the molding process in mice of different ages and presented age-dependent vascular embolism ***,we integrated optical coherence tomography angiography to investigate age-associated trends in cerebrovascular variability following a *** imaging data and quantitative analyses underscore the differential cerebrovascular responses to stroke in mice of different ages,thereby highlighting the technique's potential for evaluating cerebrovascular health and unraveling age-related mechanisms involved in ischemic strokes.

关键词： age-dependent cerebral cortex ischemic stroke mouse model optical coherence tomography angiography photoacoustic microscopy photothrombosis vascular imaging

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Clinical effects of phospholipase D2 in attenuating acute pancreatitis

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World Journal of Gastroenterology 2025年第2期31卷 52-60页

作者： Jin-Wei Niu Guo-Chao Zhang Wu Ning Hai-bin liu Hua Yang Chao-Feng Li Department of General Surgery China-Japan Friendship HospitalBeijing 100029China

BACKGROUND The objective of the current study was to elucidate the clinical mechanism through which phospholipase D2(PLD2)exerted a regulatory effect on neutrophil migra-tion,thereby alleviating the progression of acute *** To elucidate the clinical mechanism through which PLD2 exerted a regulatory effect on neutrophil migration,thereby alleviating the progression of acute *** The study involved 90 patients diagnosed with acute pancreatitis,admitted to our hospital between March 2020 and November 2022.A retrospective analysis was conducted,categorizing patients based on Ranson score severity into mild(n=25),moderate(n=30),and severe(n=35)*** data was collected for each *** blot analysis assessed PLD2 protein expression in patient ***-time reverse transcription polymerase chain reaction was used to evaluate the mRNA expression of chemokine receptors associated with neutrophil *** levels of inflammatory factors in patients were detected using enzyme-linked immunosorbent *** migration tests were conducted to compare migration of neutrophils across groups and analyze the influence of PLD2 on neutrophil *** Overall data analysis did not find significant differences between patient groups(P>0.05).The expression of PLD2 protein in the severe group was lower than that in the moderate and mild groups(P<0.05).The expression level of PLD2 in the moderate group was also lower than that in the mild group(P<0.05).The severity of acute pancreatitis is negatively correlated with PLD2 expression(r=-0.75,P=0.002).The mRNA levels of C-X-C chemokine receptor type 1,C-X-C chemokine receptor type 2,C-C chemokine receptor type 2,and C-C chemokine receptor type 5 in the severe group are significantly higher than those in the moderate and mild groups(P<0.05),and the expression levels in the moderate group are also higher than those in the mild group(P<0.05).The levels of C-reactive protein,tumo

关键词： Phospholipase D2 Neutrophil migration Acute pancreatitis Retrospective analysis Inflammatory response

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Fucoxanthin improves serum lipids,liver metabolism and gut microbiota in hyperlipidemia mice

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Food Science and Human Wellness 2025年第1期14卷 236-249页

作者： Yonghui Zhou Jingyi Zhang Kun Xu Weihao Zhang Feng Chen bin liu bingbing Guo Faculty of Environment and Life Beijing University&TechnologyBeijing 100124China Shenzhen Key Laboratory of Marine Microbiome Engineering Institute for Carbon NeutralityInstitute for Advanced StudyShenzhen UniversityShenzhen 518060China

Fucoxanthin,a kind of exclusively algae-derived carotenoids,could reduce lipid content and regulate gut microbiota composition in obese mice,showing potential in preventing *** study aimed to illustrate fucoxanthin efficacy in modulating lipid metabolism in serum and liver of high-fat-induced hyperlipidemia mice,as well as investigate the underlying association with gut microbiota *** showed that fucoxanthin significantly reduced body weight gain and body white fat of the *** the serum,total triglycerides(TG),total cholesterol(TC)contents were significantly decreased and high-densitylipoprotein cholesterol levels was significantly ***,fucoxanthin remarkedly prevented lipid accumulation in the ***,metabolomics results showed that lipids and lipid-like molecules were significantly downregulated compared with the control,indicating the advance of hepatic lipid *** acids profile in the liver was also greatly changed by ***,fucoxanthin remodeled gut microbiota composition and promoted the relative abundance of Desulfovibrio,Blautia and Clostridia ***,correlation analysis revealed that these gut microbiota changes were closely related with hepatic metabolites/metabolism and serum ***,this study showed great potential of fucoxanthin in improving serum lipids profile,hepatic lipids and bile acids metabolism of hyperlipidemia mice,which was associated with gut microbiota alteration.

关键词： Fucoxanthin Lipids Hyperlipidemia Liver metabolism Gut microbiota

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Assembly between diverse polycations and diamond-like anionic frameworks in salt-inclusion phosphides enables excellent nonlinear optical properties

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Science China Chemistry 2025年

作者： Ming-Shu Zhang Shao-Min Pei bin-Wen liu Xiao-Ming Jiang Guo-Cong Guo State Key Laboratory of Structural Chemistry Fujian Institute of Research on the Structure of MatterChinese Academy of Sciences University of Chinese Academy of Sciences Fujian Science&Technology Innovation Laboratory for Optoelectronic Information of China

Diamond-like （DL） structure facilitates optimal superposition of the second-order polarizability in tetrahedra,rendering it a widely adopted template for nonlinear optical （NLO） *** phosphides,serving as potential employers for infrared（IR） NLO materials,have persisted in an underdeveloped state for a considerable duration due to the difficulty of *** this work,we strategically opted for the[Sr4Br]tetrahedra and[Ba2Sr4Br2]∞chain as polycations,leading to the successful formation of two novel salt-inclusion phosphides featuring DL anionic frameworks:[Ba2Sr4Br2][Sr4Br][In5Si31P52]（1） and[Sr4Br][In2Si11P19]（2）.Both phosphides exhibit the remarkable structural characteristics of T3-supertetrahedra,which is rarely observed in IR nonlinear optical （NLO） ***,a tenfold enhancement in the intensity of phase-matching secondharmonic generation （SHG） is observed in phosphide 2 （2.1×AgGaS2） compared to that in 1 （0.2×AgGaS2）,which can potentially be attributed to the significant distinct distorted degrees and stacking methods demonstrated by[InP4],[SiP4]and[In/SiP4]tetrahedra impacted by ***,both phosphides 1 and 2 display moderate optical bandgaps （1.70 and1.87 eV）,large laser-induced damage thresholds （LIDT,6.0 and 5.0×AGS@2090 nm）,and excellent infrared *** present study provides a novel avenue for the flourishing development of diamond-like structures and salt-inclusion phosphides.

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A Method to Assess the Applicability and Accuracy of the Modified Gaussian Model(MGM) on the Rock Samples' Spectral Interpretation

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Research in Astronomy and Astrophysics 2025年第1期25卷 175-183页

作者： Fang Gao bin liu Qin Zhou Chun-Lai Li Key Laboratory of Lunar and Deep Space Exploration Chinese Academy of Sciences National Astronomical Observatories Chinese Academy of Sciences University of Chinese Academy of Sciences

The Chang’e-4 mission obtained spectral data of multiple rock targets on the lunar *** Modified Gaussian Model (MGM) is usually applied to the spectral interpretation of powder samples,its applicability and accuracy on the rock targets remain to be further *** rock slice of lunar meteorite NWA 4734 is used to conduct comprehensive analysis of the petrography,mineralogy and laboratory spectroscopy,which will provide important ground truth for the MGM interpretation of lunar in situ spectra of rock ***,a scanning electron microscope (SEM),Energy Dispersive Spectrometer (EDS),and Electron Probe Micro-Analyzer (EPMA) analysis results indicate that:(1) almost all plagioclase in NWA 4734 have been converted to maskelynites,which indicate that the meteorite has undergone severe impact metamorphism;(2) the chemical composition of pyroxene and olivine is significantly heterogeneous,showing a distribution characteristic of magnesium-rich core and iron-rich rim,further indicating that NWA 4734 has undergone multiple crystallization and ***,this article focuses on the rock slice of NWA 4734's greyscale image of the Back Scattering Electron (BSE),and obtains the proportion of High-Calcium Pyroxene (HCP) in the total pyroxenes of this sample by calculating the area percentage using the pixel counting *** result shows that the proportion of HCP is 72%±5.4%,which can be used as a ground truth to evaluate the interpretation applicability and accuracy of MGM.A field spectrometer (ASD) is used to measure the visible and near-infrared reflectance spectra (450–2500 nm) of the rock slice from NWA 4734 in the same area as the BSE image obtained by SEM,and MGM is used to deconvolve the ASD spectra,and the average proportion of HCP is estimated to be 71%±10.1%.The results between the MGM and the pixel counting are comparable within the error range,which demonstrates the applicability of MGM on interpretation of the rock samples on the lu

关键词： astrochemistry instrumentation: spectrographs methods: data analysis

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Weak feedback self-mixing interference fringe slope discrimination method based on deep learning

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Optoelectronics Letters 2025年

作者： ZHAO Yan LIN Maohua DU Shengzhi TONG Jigang liu bin HAN Fangfang School of Electrical Engineering and Automation， Tianjin University of Technology Tianjin Key Laboratory for Control Theory and Applications in Complicated Systems Department of Electrical Engineering， Tshwane University of Technology

In order to identify the tilt direction of the self-mixing interference (SMI) signals under weak feedback regime interfered by noise， a deep learning method is proposed. The one-dimensional U-Net (1D U-Net) neural network can discriminate the direction of self-mixing fringes accurately and quickly. For experimental SMI signals， the 1D U-Net can be used for discriminant direction after a one-step normalization. Simulation and experimental results show that the proposed method is suitable for SMI signals with noise within the whole weak feedback regime， and can maintain a high discrimination accuracy for signals interfered by 5dB noise. Combined with fringe counting method， accurate and rapid SMI signal displacement reconstruction can be realized.

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基于电感复用的准谐振型变换器

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电网技术 2025年第2期49卷 781-789,I0105,I0106页

作者：王昊刘斌许国徐菁涛广西大学电气工程学院广西壮族自治区南宁市530004 广西电力系统最优化与节能技术重点实验室(广西大学) 广西壮族自治区南宁市530004 中南大学自动化学院湖南省长沙市410083 中南大学交通运输工程学院湖南省长沙市410075

针对新能源发电系统对隔离DC-DC变换器宽电压范围的需求,提出一种基于电感复用的宽范围准谐振型变换器。通过引入谐振技术,变换器在合理的参数设计下可以实现一次侧开关管零电压开关(zero voltage switching,ZVS)导通以及二次侧二极管... 详细信息

针对新能源发电系统对隔离DC-DC变换器宽电压范围的需求,提出一种基于电感复用的宽范围准谐振型变换器。通过引入谐振技术,变换器在合理的参数设计下可以实现一次侧开关管零电压开关(zero voltage switching,ZVS)导通以及二次侧二极管零电流开关(zero current switching,ZCS)关断,解决了传统倍流整流变换器ZVS实现和占空比丢失相矛盾的问题;采用电感复用的思想,无须将变压器的励磁电感设计得过小,即可实现宽范围调压,在较窄的开关频率范围内有效提升了电压增益范围;相较于全波整流,优化了变压器的绕组利用率。结合变换器的工作特性,分析推导了所提出变换器的软开关条件和电压增益,继而给出了谐振参数设计方法;最后通过一台800W样机的实验验证了变换器拓扑的可行性与理论分析的正确性。

关键词： DC-DC变换器电感复用宽范围谐振零电压开关零电流开关

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应用改善病情抗风湿药物治疗骨关节炎之争

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协和医学杂志 2025年第1期16卷 13-18页

作者：崔涵姝刘斌青岛大学附属医院风湿免疫科山东青岛266000

骨关节炎(osteoarthritis, OA)是一种退行性关节软骨病变,病理特征为骨赘形成和软骨下骨损伤,可导致患者关节疼痛、僵硬、畸形甚至残疾,并增加其他疾病的发生风险。目前,OA发病的具体分子机制尚不明晰,临床缺乏特异性治疗靶点,现有药物... 详细信息

骨关节炎(osteoarthritis, OA)是一种退行性关节软骨病变,病理特征为骨赘形成和软骨下骨损伤,可导致患者关节疼痛、僵硬、畸形甚至残疾,并增加其他疾病的发生风险。目前,OA发病的具体分子机制尚不明晰,临床缺乏特异性治疗靶点,现有药物疗效有限,且可能引发不良事件,使得OA治疗面临诸多挑战。一些学者认为滑膜炎症是OA疼痛与疾病进展的主要原因,建议将治疗炎性关节炎的改善病情抗风湿药物(disease-modifying anti-rheumatic drugs, DMARDs)用于治疗OA。然而,也有学者持反对观点,认为炎症并非OA核心驱动因素,已有研究结果也不足以支持DMARDs应用于OA的治疗。此外,药物副作用和监测要求限制了DMARDs在OA治疗中的应用,尤其对于患有合并症的老年患者。本文基于OA炎症与疼痛机制,结合国内外相关研究成果,对这一争论进行分析和讨论。

关键词：骨关节炎改善病情抗风湿药物治疗甲氨蝶呤

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