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Advances in Cervical Artificial Disc Replacement for Cervical Spondylosis

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Expert Review of Chinese Medical

Expert Review of Chinese Medical 2024年第1期2卷 27-31页

作者： bin fan fanghe Luo Yue Ma The First Clinical Medical College of Mudanjiang Medical College

Anterior cervical decompression and fusion(ACDF)treatment for cervical spondylosis has been more than half a century,and achieved good clinical results.However,with the continuous extension of follow-up time,the fusion segment-associated postoperative complications emerged gradually.Reserved cervical stability and activity,the concept of non-fusion was born.As a non-fusion technique,cervical artificial disc replacement(CADR)developed rapidly.With the continuous development of artificial prosthesis materials and design concepts,and specification and proficiency of surgical procedures,CADR has achieved better short and mid-term clinical efficacy than ACDF.Compared with ACDF,the main advantages of CADR are that the postoperative recovery is quick,the activity and stability of cervical vertebra are maintained,the height of cervical intervertebral space is restored,and the stress of adjacent segments and the rate of surgical renovation are reduced.In clinical work,as an emerging technology,CADR requires spine surgeons to control the surgical indications,contraindications,and patients'conditions strictly.This article reviews the research progress of CADR in order to provide new ideas for clinical treatment of cervical spondylosis.

关键词： cervical artificial disc replacement anterior cervical decompression and fusion adjacent segment degeneration cervical spondylosis research progress

Rolling Shutter Camera:Modeling,Optimization and Learning

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Machine Intelligence Research 2023年第6期20卷 783-798页

作者： bin fan Yuchao Dai Mingyi He School of Electronics and Information Northwestern Polytechnical UniversityXi’an710129China

Most modern consumer-grade cameras are often equipped with a rolling shutter mechanism,which is becoming increasingly important in computer vision,robotics and autonomous driving applications.However,its temporal-dynamic imaging nature leads to the rolling shutter effect that manifests as geometric distortion.Over the years,researchers have made significant progress in developing tractable rolling shutter models,optimization methods,and learning approaches,aiming to remove geometry distortion and improve visual quality.In this survey,we review the recent advances in rolling shutter cameras from two aspects of motion modeling and deep learning.To the best of our knowledge,this is the first comprehensive survey of rolling shutter cameras.In the part of rolling shutter motion modeling and optimization,the principles of various rolling shutter motion models are elaborated and their typical applications are summarized.Then,the applications of deep learning in rolling shutter based image processing are presented.Finally,we conclude this survey with discussions on future research directions.

关键词： Rolling shutter motion modeling image correction temporal super-resolution deep learning

Immunomodulatory Function of Pien Tze Huang in T Cell-Mediated Anti-tumor Activity against B16-F10,MC38 and Hep1-6 Tumor Models

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Chinese Journal of Integrative Medicine 2024年第4期30卷 348-358页

作者： FU Yu-bing LIU Chen-feng WANG Jin-jia JI Xiao-lin TANG Rong-han LIAO Kun-yu CHEN Ling-yue HONG Ya-zhen fan bin-bin WANG Shi-cong LIU Wen-Hsien State Key Laboratory of Cellular Stress Biology School of Life SciencesFaculty of Medicine and Life ScienceXiamen UniversityXiamenFujian Province(361102)China Fujian Pien Tze Huang Enterprise Key Laboratory of Natural Medicine Research and Development ZhangzhouFujian Province(363000)China

Objective To investigate the anti-tumor effects of Pien Tze Huang(PZH)in mouse models of B16–F10 melanoma,MC38 colorectal cancer,Hep1-6 hepatocellular carcinoma and chemically induced hepatocellular carcinoma model.Methods Various tumor models,including B16–F10,MC38 and Hep1-6 tumor hypodermic inoculation models,B16–F10 and Hep1-6 pulmonary metastasis models,Hep1-6 orthotopic implantation model,and chemically induced hepatocellular carcinoma model,were utilized to evaluate the anti-tumor function of PZH.Tumor growth was assessed by measuring tumor size and weight of solid tumors isolated from C57BL/6 mice.For cell proliferation and death of tumor cells in vitro,as well as T cell activation markers,cytokine production and immune checkpoints analysis,single-cell suspensions were prepared from mouse spleen,lymph nodes,and tumors after PZH treatment.Results PZH demonstrated significant therapeutic efficacy in inhibiting tumor growth(P0.05).Nevertheless,PZH exhibited a remarkable ability to enhance T cell activation and the production of interferon gamma,tumor necrosis factor alpha,and interleukin 2 in CD4^(+)T cells in vitro(P<0.01 or P<0.05).Importantly,PZH substantially inhibited T cell exhaustion and boosted cytokine production by tumor-infiltrating CD8^(+)T cells(P<0.01 or P<0.05).Conclusion This study has confirmed a novel immunomodulatory function of PZH in T cell-mediated anti-tumor immunity,indicating that PZH holds promise as a potential therapeutic agent for cancer treatment.

关键词： Pien Tze Huang metastasis anti-tumor immunity T cell activation T cell exhaustion immune checkpoints Chinese medicine

Stress sensitivity of coal reservoir and its impact on coalbed methane production in the southern Qinshui Basin, north China

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Frontiers of Earth Science 2023年第1期17卷 4-17页

作者： Huimin JIA Yidong CAI Qiujia HU Cong ZHANG Feng QIU bin fan Chonghao MAO CBM Exploration and Development Branch PetroChina Huabei Oilfeld CompanyChangzhi 046000China School of Energy Resources China University of GeosciencesBeijing 100083China

Stress sensitivity has significant negative effects on the permeability and production of coalbed methane(CBM)reservoirs.To effectively minimize these negative effects,the degree of stress sensitivity during the CBM production process should be carefully studied.In this work,the curvature of the stress-sensitivity curve was adopted to explore the degree of stress sensitivity,dividing the stress-sensitivity curve and the drainage process into five stress stages:sharp decrease,rapid decrease,low-speed decrease,slower decrease and harmless with four critical stress points—transition,sensitivity,relief and harmless.The actual stages were determined by the initial permeability,stress-sensitivity coefficient and difference between the reservoir pressure and desorption pressure.The four critical stress points did not completely exist in the stress-sensitivity curve.With an increase in the initial permeability of coal,the number of existing critical stresses increases,leading to different gas-water drainage strategies for CBM wells.For reservoirs with a certain stress-sensitivity coefficient,the permeability at the sensitive stress point was successively greater than that at the transition,relief and the harmless stresses.When the stress-sensitivity coefficient is different,the stage is different at the beginning of drainage,and with an increase in the stress-sensitivity coefficient,the decrease rate of the permeability increases.Therefore,the stress-sensitivity coefficient determines the ability to maintain stable CBM production.For well-fractured CBM reservoirs,with a high stress-sensitivity coefficient,permeability damage mainly occurs when the reservoir pressure is less than the relief stress;therefore,the depressurization rate should be slow.For CBM reservoirs with fewer natural fractures,the reverse applies,and the depressurization rate can be much faster.The higher the difference between the reservoir and desorption pressures,the higher the effective stress and permeability damage after desorption,resulting in a m

关键词： coalbed methane stress sensitivity curvature stages division drainage

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光学元件磁流变加工不确定度误差工艺方法

红外与激光工程 2024年第3期53卷 203-212页

作者：高博范斌王佳吴湘辛强光场调控科学技术全国重点实验室四川成都610209 中国科学院先进光学研制中心四川成都610209 中国科学院光电技术研究所四川成都610209 中国科学院大学北京100049

为减少磁流变抛光过程中误差对加工精度的影响,实现光学元件磁流变高精度加工,采用一种不确定度误差工艺方法对加工中的误差进行抑制。通过对磁流变加工过程中的位置误差和去除函数误差进行不确定度分析,在理论分析与实验分析的基础上... 详细信息

为减少磁流变抛光过程中误差对加工精度的影响,实现光学元件磁流变高精度加工,采用一种不确定度误差工艺方法对加工中的误差进行抑制。通过对磁流变加工过程中的位置误差和去除函数误差进行不确定度分析,在理论分析与实验分析的基础上进行验证实验。由仿真与实验结果可知,加工中面形误差与中频误差均存在3.5 nm的不确定度误差值,通过验证实验,得到了加工后的面形误差RMS值为20 nm,中频误差RMS值为14 nm。结果表明,采用误差不确定度的方法可优化加工工艺流程,减少误差对加工过程的影响,可以达到不确定度下的面形精度。该方法为磁流变高精度确定性加工以及面形误差与中频误差的抑制问题提供了一种解决方案。

关键词：光学加工面形误差磁流变抛光中频误差

Anaerobic treatment of source-separated domestic bio-wastes with an improved upflow solid reactor at a short HRT

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Journal of Environmental Sciences 2018年第4期30卷 255-264页

作者： Hongliang Wang Shikun Zhu Bo Qu Yu Zhang bin fan State Key Laboratory of Environmental Aquatic Chemistry Research Center for Eco-Environmental Sciences Chinese Academy of SciencesBeijing 100085 China University of Chinese Academy of Science Beijing 100049 China

Anaerobic treatment is the core technology for resource and energy recovery from source-separated domestic bio-wastes. The higher efficiency of an improved upflow solid reactor（IUSR） designed in this study was demonstrated in the treatment of concentrated black water and kitchen waste. The highest methane production of 48 L/person/day was achieved at the hydraulic retention time（HRT） of 7 days, while the other measures of performance at the HRT of 8.3 days were better than at the HRT of 7 or 10 days, achieving a methane production of 43 L/person/day, removal of total chemical oxygen demand（TCOD）of 89%, removal of soluble chemical oxygen demand（SCOD） of 92%, and conversion of chemical oxygen demand（COD） to methane of 71%. It is not recommended to decrease HRT lower than 7 days due to the instability of the initial period. The concentrations of volatile fatty acids（VFAs） in the IUSR were less than 10 mg/L, indicating that the anaerobic process was stable. Sludge bed development showed that sludge bed with high microbial activity was formed in the bottom and that the precipitation zone of effluents formed should preferably occupy 30% of the height of the IUSR. The effluents of the IUSR could be used for irrigation in agriculture in combination with a settling tank accompanied by disinfection to remove solids and pathogens.

关键词： Sustainable sanitation Anaerobic treatment Source-separated domestic bio-wastes Improved upflow solid reactor

从微观干预到宏观进路:慢性病疾痛叙事视角下的医务社会工作行动方略

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福建论坛（人文社会科学版） 2024年第5期 114-125页

作者：范斌谢春艳华东理工大学社会与公共管理学院上海市卫生和健康发展研究中心(上海市医学科学技术情报研究所)

人口老龄化和疾病谱改变使得慢性病患者群体日益庞大,慢性病患者的疾痛叙事和叙事治疗也成为医务社会工作研究和实践的重要范式。着眼于慢性病疾痛叙事中的患病经历和临床遭遇,不难发现除了疾病带来的身心痛苦,医药市场、医学权力及医... 详细信息

人口老龄化和疾病谱改变使得慢性病患者群体日益庞大,慢性病患者的疾痛叙事和叙事治疗也成为医务社会工作研究和实践的重要范式。着眼于慢性病疾痛叙事中的患病经历和临床遭遇,不难发现除了疾病带来的身心痛苦,医药市场、医学权力及医疗制度等医疗生态环境是慢性病疾痛叙事的社会根源。医务社会工作对慢性病患者疾痛叙事的研究与实务,不应局限于微观意义上对个体身心痛苦的干预和缓解,还要有更多的社会关怀,去发现和揭露医疗生态环境中存在的问题,进行价值引导和政策倡导,参与构建整合型服务与社区健康共同体,寻找推动医疗制度与医疗生态环境改变的可能性。

关键词：疾痛叙事医务社会工作个体干预医疗生态环境

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合作与创新:社会组织可持续发展的根本途径——基于G省J市A协会的个案研究

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学术论坛 2024年第2期47卷 90-101页

作者：范斌闭珎尔华东理工大学社会与公共管理学院上海200237

针对社会组织研究传统范式中过度强调政府与社会、组织与环境之间“二元对立”的倾向,文章以G省J市A协会为个案,试图从合作博弈和创新理论的双重视角,通过对其转型发展过程的系统考察,阐明合作与创新对社会组织可持续发展的深远意义。... 详细信息

针对社会组织研究传统范式中过度强调政府与社会、组织与环境之间“二元对立”的倾向,文章以G省J市A协会为个案,试图从合作博弈和创新理论的双重视角,通过对其转型发展过程的系统考察,阐明合作与创新对社会组织可持续发展的深远意义。研究发现,A协会之所以能够从一个“草根组织”成功转型为当地发展势头强劲的志愿服务机构,关键在于它主动选择了合作与创新的行动策略。通过这一典型案例发现,一方面,社会组织的合作行为在中国具有独特的政治优势和文化优势,使之能够被纳入国家治理的总体框架而得以有效地实现;另一方面,社会组织创新在中国具有悠久的历史基础、深厚的文化积淀、迫切的现实需要和强大的实践主体,加之创新内容和形式的多元性特征,使之具备了可持续发展的更大可能性和可行性。因此,坚持合作与创新“两条腿走路”,是社会组织谋求可持续发展的必然选择。

关键词：社会组织国家治理基层治理治理现代化可持续发展

数字中国建设水平测度、地区差异及收敛性研究

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统计与决策 2024年第9期40卷 79-84页

作者：李鹏飞范斌华东理工大学社会与公共管理学院上海200237

文章基于数字基础设施建设、数字技术创新、数字经济、数字社会、数字政府、数字化发展环境、网络安全七个维度,构建数字中国建设水平评价指标体系,对2015—2021年我国30个省份数字中国建设水平进行测度。结果表明:数字中国建设水平表... 详细信息

文章基于数字基础设施建设、数字技术创新、数字经济、数字社会、数字政府、数字化发展环境、网络安全七个维度,构建数字中国建设水平评价指标体系,对2015—2021年我国30个省份数字中国建设水平进行测度。结果表明:数字中国建设水平表现出递增趋向但总体水平较低,数字技术创新和数字政府建设水平有待进一步提高;东部、中部、西部地区数字中国建设水平具有显著梯度差,呈现“东部高、西部低”的空间分布格局;区域差异分析结果显示,观测期内数字中国建设水平整体差异表现出“U”型特点,差异主要来源于区域间差异;收敛机制分析结果表明,全国及三大地区数字中国建设水平具有绝对β收敛和条件β收敛特征。

关键词：数字中国区域差异变异系数法数字技术创新

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