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Evaluation of phytochemical properties and larvicidal activities of Cynodon dactylon, Clerodendrum viscosum, Spilanthes acmella and Terminalia chebula against Aedes aegypti

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Asian Pacific Journal of Tropical Medicine 2019年第5期12卷 224-231页

作者： Ananta Swargiary Manita Daimari Mritunjoy Roy Dipanjali Haloi bijit Ramchiary Department of Zoology Bodoland University Department of Zoology Kokrajhar Govt.College

Objective: To investigate the phytochemical, antioxidant and larvicidal property of Cynodon dactylon, Clerodendrum viscosum, Spilanthes acmella and Terminalia chebula against Aedes ***: Antioxidant capacity of methanolic extract of the plants was studied by 2,2-Diphenyl-1-picryl-hydrazyl-hydrate(DPPH) assay, ferric reducing antioxidant power assay, 2,2'-azinobis-(3-ethylbenzothiazoline-6-sulfonate) assay(ABTS), thiobarbituric acid reactive substance(TBARS) assay, superoxide anion scavenging activity and total antioxidant activity assay following standard *** phenolic content, total flavonoid content, carbohydrate, and plant protein were also estimated following standard *** property of plant extracts were determined following World Health Organization standard ***, glutathione-s-transferase(GST) and acetylcholinesterase(AchE) inhibitory property was also tested ***: Phytochemically, high protein, carbohydrate and phenolic were found in Terminalia chebula, while Cynodon dactylon showed high flavonoid ***, high antioxidant activity was found in Terminalia chebula with IC_(50) values at 13.7, 2.9, 45.2 and 46.0 μg/mL in DPPH, ABTS, TBARS and superoxide anion scavenging activity, *** study showed strongest activity in Spilanthes acmella followed by Cynodon dactylon, and Clerodendrum viscosum and Terminalia *** and AchE of Aedes aegypti larvae showed reduced enzyme activity when pre-incubated with Cynadon dactylon and Spilanthes ***: The methanolic crude extracts of Cynodon dactylon, Clerodendrum viscosum, Spilanthes acmella and Terminalia chebula possess strong antioxidant and larvicidal property against Aedes aegypti and therefore, may be further investigated for the molecular mode of action.

关键词： Larvicide Glutathione S-transferase Acetylcholinesterase Udalguri district Aedes aegypti

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Risk factors of COVID-19 infection among policemen: A case-control study

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Journal of Acute Disease 2020年第6期9卷 263-269页

作者： Neeraj Agarwal bijit biswa. Department of Community and Family Medicine All India Institute of Medical SciencesPatnaBiharIndia

Objective:To investigate the risk factors and protective measures of COVID-19 among policemen in an eastern state of ***:This case-control study was conducted in Bihar,located in the eastern part of *** total,6 confirmed COVID-19 cases(the case group)and 11 negative contacts of these cases(the control group)of Bihar Military Police participated in the ***:All subjects were male with a median age of 51(range:23-60)*** these 6 confirmed cases,5 cases were *** third(33.3%)of the case group and the majority(90.9%)of the control group reported maintenance of physical distance of at least 1 meter with others all the time,which was significantly different(P=0.028).There was no other statistically significant difference between the case group and the control ***:Physical distancing is the most effective public health measure to control contagious diseases like COVID-19,especially in the absence of an effective vaccine in police settings.

关键词： COVID-19 Police Epidemiology Risk factors Protective factors

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Clinicopathological Profile of Lung Cancers at an Institute from South India—A Record Based Retrospective Cohort Study

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Advances in Lung Cancer 2020年第3期9卷 41-54页

作者： Vinod Ramani Choudhury bijit Sarathy Vinu Jayappa Srinivas Belagutti Naik Radheshyam HealthCare Global Enterprise Ltd. Bangalore India Biocon Bangalore India

Introduction: Apart from smoking as the known risk factor for lung cancer, recent developments implicate occupational exposure to carcinogens, indoor air pollution and dietary factors as other causative agents. In our study, we have analyzed the clinical and pathological profile of lung cancer patients treated at our center over a period of 8 years. Aim: To find the demographic and clinicopathological profile of lung cancer patients admitted to the oncology unit. Methods: This retrospective record based analysis includes a cohort of 1248 patients diagnosed with lung cancer, at a tertiary cancer care center in Bangalore, South India. This study includes data of patients admitted during the period 2010 to 2018, retrieved from the Hospital’s emergency medical records (EMR). Their demographic profile, clinical correlates, radiological profile and diagnostic details were studied. Benign tumours, malignant pleural disease and sarcomatoid tumors were excluded from this study. Results: Adenocarcinoma (AC) was detected among 70.4% of patients, Squamous cell carcinoma (SCC) among 15.3% and Small cell lung cancer (SCLC) among 14.3% of lung cancer admissions. Male to female ratio was 2.95:1. It was found that the median age of lung cancer patients was 61 years. >60% of lung cancer patients were from the 51 - 70 year age-group. Across the three types of cancers among the patients in Stage 3B to 4 strata, >35% received palliative chemotherapy and >20% received palliative chemotherapy + radiation. Conclusion: In our study, AC is the most common histological subtype (>70%) of lung cancer. The outcome of lung cancer patients can be considerably impacted by addressing risk factors through preventive measures implemented in the community.

关键词： Lung Neoplasms Adenocarcinoma Squamous Cell Carcinoma Small Cell Lung Carcinoma

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