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Assessing myocardial indices and inflammatory factors to determine anxiety and depression severity in patients with chronic heart failure

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World Journal of Psychiatry 2024年第1期14卷 53-62页

作者： Li Zhang Qiang wang Hong-Sheng Cui Yuan-Yuan Luo Department of Cardiology Jingzhou HospitalYangtze UniversityJingzhou 434020Hubei ProvinceChina Department of Intensive Care Unit The First Affiliated Hospital of Guangzhou University of Chinese MedicineGuangzhou 510000Guangdong ProvinceChina

BACKGROUND Patients with chronic heart failure(CHF)have a progressive disease that is associated with poor quality of life and high *** patients experience anxiety and depression(A&D)symptoms,which can further accelerate disease *** hypothesized that indicators of myocardial function and inflammatory stress may reflect the severity of A&D symptoms in patients with *** in these biomarkers could potentially predict whether A&D symptoms will deteriorate further in these *** To measure changes in cardiac and inflammatory markers in patients with CHF to determine A&D severity and predict *** We retrospectively analyzed 233 patients with CHF treated at the Jingzhou Hospital,Yangtze University between 2018-2022 and grouped them according to Self-Rating Anxiety Scale(SAS)and Self-Rating Depression Scale(SDS)*** compared clinical data in the no-A&D,mild-A&D,moderate-A&D,and severe-A&D groups,the SAS and SDS scores with the New York Heart Association(NYHA)functional classification,and cardiac markers and inflammatory factors between the no/mild-A&D and moderate/severe-A&D *** analysis was performed on the markers with P0.05).In addition,we found that higher NYHA classes were associated with higher the SAS and SDS scores(P<0.05).Regression analysis showed that LVEF,NTproBNP,and IL-6 were independent risk factors for A&D severity(P<0.05).Among them,NT-pr

关键词： Chronic heart failure Anxiety Depression Cardiac markers Inflammatory factors Prediction

Role Dynamic Allocation of Human-Robot Cooperation Based on Reinforcement Learning in an Installation of Curtain Wall

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工程与科学中的计算机建模(英文) 2024年第1期138卷 473-487页

作者： Zhiguang Liu Shilin wang Jian Zhao Jianhong Hao Fei Yu School of Control and Mechanical Engineering Tianjin Chengjian UniversityTianjin300384China Comprehensive Business Department CATARC(Tianjin)Automotive Engineering Research Institute Co.Ltd.300339China School of Mechanical Engineering Hebei University of TechnologyTianjin300130China

A real-time adaptive roles allocation method based on reinforcement learning is proposed to improve humanrobot cooperation performance for a curtain wall installation *** method breaks the traditional idea that the robot is regarded as the follower or only adjusts the leader and the follower in *** this paper,a self-learning method is proposed which can dynamically adapt and continuously adjust the initiative weight of the robot according to the change of the ***,the physical human-robot cooperation model,including the role factor is ***,a reinforcement learningmodel that can adjust the role factor in real time is established,and a reward and actionmodel is *** role factor can be adjusted continuously according to the comprehensive performance of the human-robot interaction force and the robot’s Jerk during the repeated ***,the roles adjustment rule established above continuously improves the comprehensive *** of the dynamic roles allocation and the effect of the performance weighting coefficient on the result have been *** results show that the proposed method can realize the role adaptation and achieve the dual optimization goal of reducing the sum of the cooperator force and the robot’s Jerk.

关键词： Human-robot cooperation roles allocation reinforcement learning

Lithiated Graphdiyne Quantum Dots for Stable Lithium Metal Anodes

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CCS Chemistry 2024年第5期6卷 1300-1311页

作者： Han Shen Congying Song Fan wang Guoxing Li Yuliang Li Shandong Provincial Key Laboratory for Science of Material Creation and Energy Conversion Science Center for Material Creation and Energy ConversionInstitute of Frontier and Interdisciplinary ScienceShandong UniversityQingdao 266237 Key Laboratory of Organic Solids Institute of ChemistryChinese Academy of SciencesBeijing 100190 University of Chinese Academy of Sciences Beijing 100049

Here,a facile strategy is proposed for the preparation of lithiated graphdiyne quantum dots(GDY-Li QDs)with conjugated sp-and sp2-hybridized carbons by the self-assembly technique ofπ–πstacking of lithiated hexaethynylbezene under mild *** as-prepared GDY-Li QDs,containing stacked multialkynyl aromatic backbone and abundant lithium(Li),show an average diameter of about 2.6 nm and good dispersion in the *** distinctive structures endow GDY-Li QDs with superior properties that cannot be matched by traditional QDs,such as strong ion adsorption,Li-ion self-concentration,high Li-ion conductivity,the nanoconfinement effect,and ion solvation *** from these features,GDY-Li QDs can stabilize Limetal anodes to effectively suppress Li-dendrite growth and significantly improve its Li plating/stripping coulombic efficiency(99.3%in the carbonate electrolyte).The full cells with GDY-Li QDs protected Li-metal anodes,and LiNi0.8Co0.1Mn0.^(1)O_(2)cathodes delivered high capacity and excellent cycling stability at high rates,which demonstrates the great potential of GDY-Li QDs for application in fast-charging Li-metal batteries.

关键词： graphdiyne quantum dots lithiation lithium metal anodes ion distribution

Divergent total synthesis of marine meroterpenoids(+)-dysidavarones A–C

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Chinese Chemical Letters 2024年第3期35卷 234-238页

作者： Qunlong Zhang Yang Kuang Le Chang Jingyi Kang Bingjian wang Chuanke Chong Zhaoyong Lu State Key Laboratory of Medicinal Chemical Biology College of PharmacyNankai UniversityTianjin 300350China

Here,we report a concise and divergent enantioselective total synthesis of marine sesquiterpene quinone meroterpenoids(+)-dysidavarones A–C(1–3)using predysidavarone 6 as a key common *** highly strained and bridged eight-membered carbocycle of predysidavarone 6 was constructed by a one-pot intermolecular alkylation and intramolecular arylation of Wieland–Miescher ketone derivative 11 and benzyl bromide *** total synthesis of(+)-dysidavarones A–C(1–3)was achieved from predysidavarone 6 in a divergent manner by a late-stage introduction of the ethoxy group,which reveals the possible source of the ethoxy group within(+)-dysidavarones A–C(1–3)and provides a late-stage modifiable route for the synthesis of dysidavarone analogs for further anti-cancer activity evaluation.

关键词： Total synthesis Natural product Dysidavarones A–C Sesquiterpene quinone Meroterpenoid

THE OPTIMAL LARGE TIME BEHAVIOR OF3D QUASILINEAR HYPERBOLIC EQUATIONS WITH NONLINEAR DAMPING

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Acta Mathematica Scientia 2024年第3期44卷 1064-1095页

作者：王涵张映辉 School of Mathematics and Statistics Guangxi Normal UniversityGuilin541004China

We are concerned with the large-time behavior of 3D quasilinear hyperbolic equations with nonlinear *** main novelty of this paper is ***,we prove the optimal decay rates of the second and third order spatial derivatives of the solution,which are the same as those of the heat equation,and in particular,are faster than ones of previous related ***,for well-chosen initial data,we also show that the lower optimal L^(2) convergence rate of the k(∈[0,3])-order spatial derivatives of the solution is(1+t)^(-(2+2k)/4).Therefore,our decay rates are optimal in this *** proofs are based on the Fourier splitting method,low-frequency and high-frequency decomposition,and delicate energy estimates.

关键词： quasilinear hyperbolic equations large time behavior optimal decay rates

Mechanisms of hyponatremia and diabetes insipidus after acute spinal cord injury:a critical review

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Chinese Neurosurgical Journal 2024年第1期10卷 42-47页

作者： Lianhua Li Yanhui Guo Chen Chen Zhonghe wang Zhi Liu Department of Orthopedics the Fourth Medical Center of PLA General HospitalBeijingChina

The incidence of hyponatremia after spinal cord injury was reported to be between 25 and 80%.Hyponatremia can lead to a variety of clinical symptoms,from mild to severe and even *** is often associated with diabetes insipidus,which refers to insufficient arginine vasopressin(AVP)secretion or defective renal response to AVP,with clinical manifestations of syndromes such as hypoosmolality,polydipsia,and *** mechanistic studies on hyponatremia and diabetes insipidus after acute spinal cord injury have been performed in isolation,without integrating the above two symptoms into different pathological manifestations that occur in the same injury state and without considering the acute spinal cord injury patient’s condition as a *** therapeutic principles of CSWS and SIADH are in opposition to one *** is not easy to identify the mechanism of hyponatremia in clinical practice,which makes selecting the treatment *** to the existing theories,treatments for hyponatremia and diabetes insipidus together are contraindicated,whether the mechanism of hyponatremia is thought to be CSWS or *** this paper,we review the mechanism of these two pathological manifestations and suggest that our current understanding of the mechanisms of hyponatremia and diabetes insipidus after high acute cervical SCI is insufficient,and it is likely that there are other undetected pathogenetic mechanisms.

关键词： Mechanism Hyponatremia Diabetes insipidus Spinal cord injury

Physical Prediction Model of Compound Hydrodynamic Unload-Load Response Ratio and Its Application in Reservoir Colluvium Landslide

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Journal of Earth Science 2024年第4期35卷 1304-1315页

作者： Lu Guo Keqiang He Honghua Liu Fandi Meng Xuchun wang School of Civil Engineering Qingdao University of TechnologyQingdao266520China Key Laboratory of Geological Safety of Coastal Urban Underground Space Ministry of Natural ResourcesQingdao266071China

It is well known that the deformation and damage of reservoir colluvium landslides are often determined by the combined dynamics of reservoir water level change and *** on the systematic analysis of the change law of reservoir water level,rainfall and displacements of reservoir colluvium landslide,this paper proposes the compound hydrodynamic action of rainfall and reservoir water as the unload-load parameter,and the landslide displacement as the unload-load response *** on this,a physical prediction model of the compound hydrodynamic unload-load response ratio of reservoir colluvium landslide was established,and the quantitative relationship between the compound hydrodynamic unload-load response ratio and its stability evolution was in-depth analyzed and *** the basis of the above research,taking Shuping landslide,a typical hydrodynamic pressure landslide as an example,the unload-load response ratio model is used to systematically evaluate and predict the stability evolution law and the change trend of the landslide under compound hydrodynamic *** prediction result shows that the variation law of the compound hydrodynamic unload-load response ratio is consistent with the dynamic evolution law of its ***,the above studies show that the compound hydrodynamic unload-load response ratio parameter is an effective displacement dynamic evaluation parameter for reservoir colluvium landslides,so it can be used in the prediction of the reservoir colluvium landslides.

关键词： landslides reservoir colluvium landslide compound hydrodynamics unload-load response ratio Shuping landslide stability evaluation

Manganese-Catalyzed Regioselective Hydroboration of Quinolines via Metal-Ligand Cooperation

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CCS Chemistry 2024年第6期6卷 1535-1546页

作者： Yujie wang Hengxu Li Haobo Yang Mingjie Fan Qiang Liu Center of Basic Molecular Science(CBMS) Department of ChemistryTsinghua UniversityBeijing 100084

Selective reduction of readily available N-heteroarenes is important in both organic synthesis and chemical ***,we describe ligand-controlled regiodivergent hydroboration of quinolines using well-defined amido-manganese catalysts,with an emphasis on the rarely reported 1,*** studies showed that 1,2-hydroboration of quinoline was kinetically favorable and reversible,whereas 1,4-hydroboration was under thermodynamic *** a 1-methyimidazolebased pincer amido-manganese complex as the catalyst,cooperative C-H…N andπ…πnoncovalent interactions between the 1-methyimidazole moiety and quinoline substrates enabled kinetic accessibility of 1,4-hydroboration,giving thermodynamically favored 1,4-hydroborated quinolines as the major *** this basis,Mn-catalyzed 1,4-hydroboration of a series of substituted quinolines proceeded smoothly in high yields.A high turnover number of 2500 was achieved in this reaction with satisfying *** transformation could be further applied to the C3-selective functionalization of quinolines,highlighting the synthetic utility of this *** contrast,using a pyridine-based pincer amido-manganese complex as the catalyst,which lacked the C-H…N interaction,the free-energy barrier for 1,4-hydroboration significantly increased through a N-B…N interaction between the“HMn-NB”species and quinoline,resulting in the kinetically favored 1,2-hydroboration product with excellent regioselectivity.

关键词： catalytic hydroboration N-heteroarenes regioselectivity manganese catalysis metal-ligand cooperation

Emergency physicians’ occupational risks in China

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World Journal of Emergency Medicine 2024年第3期15卷 232-234页

作者： Huaying Jiang Jia Chang Rong Huang Xiayi Liang Manning Song Hejing Yuan Shuo wang School of Chinese Materia Medica Beijing University of Chinese MedicineBeijing 100105China Operation Room Beijing Chaoyang HospitalCapital Medical UniversityBeijing 100020China School of Marxism Beijing University of Chinese MedicineBeijing 100105China Department of Infectious Diseases(Fever Clinic) Beijing Hospital of Traditional Chinese MedicineCapital Medical UniversityBeijing 100010China

With the rapid development of emergency medicine,emergency physicians are working around the clock,[1]including additional workloads due to sudden public health emergencies and *** risks for emergency physicians are s... 详细信息

关键词： physician acute occupational