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Fatal intracranial bleedings in a viper bite:A case report

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Chinese Journal of Traumatology 2023年第2期26卷 121-124页

作者： Alagarasan Naveen Manas Ranjan Sahu Manoj kumar Mohanty Kimi Soumya padhi Ashis Patnaik Department of Forensic Medicine&Toxicology All India Institute of Medical Sciences(AMS)BhubaneswarOdishaIndia Department of Neurosurgery Al India Institute of Medical Sciences(AIIMS)BhubaneswarOdishaIndia

Viper bite envenomation represents a significant occupational hazard among agricultural workers in *** viper bite envenomation is usually suspected when a patient presents with predominant local symptoms at the bitten site,including pain,swelling,and ***,systemic findings such as diffuse intravascular coagulation,hypotension,and shock may alert physicians of viper bite envenomation rather than a neurotoxic snake ***,cerebral complications are rare in viper bites but may potentially *** nervous system involvement in a viper bite is either due to neurotoxins or hemorrhagins present in the venom,which may induce cerebral thrombosis,ischemia,infarction,and *** we present a case of a previously healthy adult male who succumbed to extensive subarachnoid,intracerebral,and intraventricular hemorrhages involving bilateral cerebral hemispheres following viper snake bite *** report highlights the importance of anticipating cerebral complications in viper bite envenomation,a rare *** also emphasizes the need for early antisnake venom administration to prevent and control systemic envenomation and its complications.

关键词： Snake bite Viper Intracerebral hemorrhage Subarachnoid hemorrhage Anti-snake venom

Bioactive peptides in fermented foods and their application:a critical review

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Systems Microbiology and Biomanufacturing 2023年第1期3卷 88-109页

作者： Rounak Chourasia Loreni Chiring Phukon Md Minhajul Abedin Srichandan padhi Sudhir P.Singh Amit kumar Rai Institute of Bioresources and Sustainable Development(DBT‑IBSD) Regional CentreTadongSikkimIndia Centre of Innovative and Applied Bioprocessing(DBT-CIAB) Sector‑81S.A.S.NagarMohaliPunjabIndia Institute of Bioresources and Sustainable Development(DBT-IBSD) Mizoram NodeAizawlMizoramIndia

Bioactive peptides are released during the production of fermented dairy,vegetables,fruits,legumes,fish,and meat *** proteolytic specificity of lactic acid bacteria,Bacillus spp.,yeasts,and mold,apart from their ability to synthesize bioactive peptides,plays an important role in the generation of specific bioactive peptides in traditional fermented *** fermentation using defined starter strains has been explored for the development of bioactive peptides enriched novel fermented foods with potential *** peptides enriched foods exert diverse health benefits,such as antioxidant,antihypertensive,antidiabetic,and immunomodulatory *** peptides can be used as alternatives to synthetic compounds due to negligible side effects and high valuation in the nutraceutical and functional food ***,challenges associated with the identification,quantification,organoleptic properties,and bioavailability of bioac-tive peptides need to be addressed before exploiting the potential of bioactive peptides in the functional food *** the present review,we have discussed the production of bioactive peptides in diverse fermented *** and sequence specificity of peptides and their effect on the expression of distinct health beneficial effects have been *** potential of utilizing these bioactive peptides for the development of novel functional fermented foods is *** advances in peptide identification,quantification,debittering of peptides,and increasing peptide bioavailability have been explained.

关键词： Bioactive peptides Fermented foods Health benefits Nutraceuticals Functional foods Bioavailability

Performance analysis of a thick copper-electroplated FDM ABS plastic rapid tool EDM electrode

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Advances in Manufacturing 2018年第4期6卷 442-456页

作者： Saroj kumar padhi S. S. Mahapatra Rosalin padhi Harish Chandra Das Department of Mechanical Engineering Koneru Lakshmiah Education Foundation Deemed to be University Vaddeswarm 522502 India Department of Mechanical Engineering National Institute of Technology Rourkela Rourkela 76900& India Department of Physics Berhampur University Berhampur 760007 India Department of Mechanical Engineering National Institute of Technology Meghalaya Shillong 793003 India

The importance of rapid tooling (RT) and additive manufacturing (AM) appears to be indispensable for boosting the process of manufacturing and expanding the horizon of production technology worldwide. This concept draws the attention of numerous scholars to arrive at a conclusive theory for the widespread utilization of RT. This study attempts to determine the viability and performance of an RT electrode in the field of electro discharge machining (EDM). The electrode prototype is made using an acrylonitrile butadiene styrene (ABS) plastic by fused deposition modeling (FDM), an AM technique, electroplated with copper of desired thickness, and used in die sinking EDM of D2 steel. The scanning electron microscope analysis of the electroplated samples confirms that it is possible to obtain the desired thickness of the metal by electroplating on any electrically conductive surfaces. In the present work, an experimental study is performed for examining the electroplated copper thickness of the plastic EDM electrode and its performances. It is found that the electroplated ABS plastic EDM RT electrode successfully performs the machining operation of D2 steel, and the results are comparable with a solid electrode. The study reveals that the RT electrode can be regarded as a viable tool for rough cutting or semi-finishing cut EDM functions. The experimental results are thoroughly discussed, examined, analyzed, and evaluated for the purpose of developing the appropriate form of the concept.

关键词： Additive manufacturing (AM) Fused deposition modeling (FDM)-Metallization of acrylonitrile butadiene styrene (ABS) plastic Reduced silver colloidal Rapid tooling (RT) Electro discharge machining (EDM)

Antioxidative,antimicrobial and anti-inflammatory activities and release of ultra-filtered antioxidative and antimicrobial peptides during fermentation of sheep milk:In-vitro,in-silico and molecular interaction studies

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Food Bioscience 2022年第3期47卷 583-594页

作者： Jodhani Keyur Ashokbhai Bethsheba Basaiawmoit Sujit Das Amar Sakure Ruchika Maurya Mahendra Bishnoi Kanthi Kiran Kondepudi Srichandan padhi Amit kumar Rai Zhenbin Liu Subrota Hatia Deptt.of Dairy Microbiology Anand Agricultural UniversityAnand388110GujaratIndia Deptt.of Rural Development and Agricultural Production North-Eastern Hill UniversityTura CampusTura794002MeghalayaIndia Deptt.of Agriculture Biotechnology Anand Agricultural UniversityAnand388110GujaratIndia Regional Center for Biotechnology FaridabadHaryana121001India Healthy Gut Research Group Food & Nutritional Biotechnology DivisionNational Agri-Food Biotechnology InstituteKnowledge CitySector 81SAS NagarPunjab140306India Institute of Bioresources and Sustainable Development Regional CentreTadong737102SikkimIndia School of Food and Biological Engineering Shaanxi University of Science and Technology18Xi'an710021China

The antioxidative,antimicrobial,and anti-inflammatory properties of fermented sheep milk with *** (KGL4),as well as the generation of antioxidative and antimicrobial peptides,are evaluated in the *** and antibacterial activities in sheep milk fermented with KGL4 increased with incubation hours,along with varied antioxidative properties (ABTS assay:35.12%,hydroxyl free radical scavenging assay:29.12%,superoxide free radical scavenging activity:36.38%).Antimicrobial activity of fermented sheep milk against *** (19 mm),*** (15.67 mm),*** (14 mm),and *** (13 mm) was also ***,after 48 h,the KGL4 showed maximum proteolysis (10.40 mg/ml) at 2.5% rate of addition sheep *** antioxidative and antimicrobial activities of fermented sheep milk fractions (3 kDa and 10 kDa permeates and retentates) were also *** highest ABTS activity (26.90%) was found in 10 kDa permeate,whereas the 3 kDa retentate had higher hydroxyl free radical scavenging activity (69.20%) and 3 kDa permeate showed maximum superoxide free radical scavenging activity (32.85%).The 10 kDa retentate had shown maximum antimicrobial activity against *** (13.67 mm) and *** (17.00 mm).Proteins spotted on 2D gel electrophoresis of KGL4 were varied from 10 to 70 ***-LC/MS was used to identify 5 novel peptide sequences from 2-D gel *** in the BIOPEP database confirmed the antioxidative and antimicrobial effects of the novel fermented sheep milk *** sheep milk with KGL4 (SMKGL4) significantly reduced excessive TNF-α,IL-6,& IL-1β production in LPS-activated RAW 264.7 cells.

关键词： Fermentation Sheep milk Lactobacillus fermentum Antioxidative Antimicrobial Anti-inflammatory Peptides

Removal efficiency of fluoride by novel Mg-Cr-Cl layered double hydroxide by batch process from water

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Journal of Environmental Sciences 2013年第5期25卷 993-1000页

作者： Sandip Mandal Swagatika Tripathy Tapswani padhi Manoj kumar Sahu Raj Kishore Patel Department of Chemistry National Institute of TechnologyRourkela 769 008India

The fluoride ion removal from aqueous solution using synthesized Mg-Cr-Cl layered double hydroxide has been ***-Cr-Cl was characterized by X-ray powder diffraction,Fourier-transform infrared,thermo-gravimetric analysis,differential thermal analysis,and scanning electron *** experiments were carried out in batch mode as a function of adsorption dosages,contact time,pH,and initial fluoride concentration to get optimum adsorption *** adsorption kinetic study showed that the adsorption process followed first order *** fluoride removal was 88.5% and 77.4% at pH 7 with an adsorbent dose of 0.6 g/100 mL solution and initial fluoride concentration of 10 mg/L and 100 mg/L,*** equilibrium was established at 40 *** experiment data were fitted well with Langmuir isotherm with R 2 = *** constants were also measured and concluded that the adsorption process was spontaneous and endothermic in *** removal percentage decreased slowly with increasing *** process is suitable for industrial *** regeneration of the material is not possible.

关键词： layered double hydroxide(LDH) fluoride adsorbents

Optimization of fused deposition modeling process parameters using a fuzzy inference system coupled with Taguchi philosophy

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Advances in Manufacturing 2017年第3期5卷 231-242页

作者： Saroj kumar padhi Ranjeet kumar Sahu S. S. Mahapatra Harish Chandra Das Anoop kumar Sood Brundaban Patro A. K. Mondal Department of Mechanical Engineering Institute of Technical Education and Research Siksha 'O' AnusandhanUniversity Bhubaneswar 751030 India Department of Mechanical Engineering SRM UniversityKattankulathur 603203 India Department of Mechanical Engineering National Institute ofTechnology Rourkela 769008 India Department of Manufacturing Engineering National Instituteof Foundry and Forging Technology Ranchi 834003 India Department of Mechanical Engineering National Institute of Technology Warangal 506004 India

Fused deposition modeling （FDM） is an additive manufacturing technique used to fabricate intricate parts in 3D, within the shortest possible time without using tools, dies, fixtures, or human intervention. This article empiri- cally reports the effects of the process parameters, i.e., the layer thickness, raster angle, raster width, air gap, part orientation, and their interactions on the accuracy of the length, width, and thicknes, of acrylonitrile-butadiene- styrene （ABSP 400） parts fabricated using the FDM tech- nique. It was found that contraction prevailed along the directions of the length and width, whereas the thickness increased from the desired value of the fabricated part. Optimum parameter settings to minimize the responses, such as the change in length, width, and thickness of the test specimen, have been determined using Taguchi＇s parameter design. Because Taguchi＇s philosophy fails to obtain uniform optimal factor settings for each response, in this study, a fuzzy inference system combined with the Taguchi philosophy has been adopted to generate a single response from three responses, to reach the specific target values with the overall optimum factor level settings. Further, Taguchi and artificial neural network predictive models are also presented in this study for an accuracy evaluation within the dimensions of the FDM fabricated parts, subjected to various operating conditions. The pre- dicted values obtained from both models are in good agreement with the values from the experiment data, with mean absolute percentage errors of 3.16 and 0.15, respectively. Finally, the confirmatory test results showed an improvement in the multi-response performance index of 0.454 when using the optimal FDM parameters over the initial values.

关键词： Fused deposition modeling (FDM) ·Dimensional accuracy · Fuzzy logic · Performance characteristic · Multi-response performance index (MRPI)Artificial neural network (ANN)