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Signal Transduction and Targeted Therapy 2024年第7期9卷 2953-2959页

作者： Sihui Luo Xueying Zheng Wei Bao Sheng Nie Yu Ding Tong yue Yilun Zhou Ying Hu Hua Li Qiongqiong yang Qijun Wan bicheng Liu Hong Xu Guisen Li Gang Xu Chunbo Chen Huafeng Liu Yongjun Shi Yan Zha Yaozhong Kong Guobin Su Ying Tang Mengchun Gong Linong Ji Fan Fan Hou Jianping Weng Department of Endocrinology First Affiliated Hospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHeifeiChina Institute of Public Health Sciences Division of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiChina Division of Nephrology National Clinical Research Center for Kidney DiseaseState Key Laboratory of Organ Failure ResearchNanfang HospitalSouthern Medical UniversityGuangzhouChina Department of Nephrology Beijing Tiantan HospitalCapital Medical UniversityBeijingChina The Second Affiliated Hospital of Zhejiang University School of Medicine HangzhouChina Sir Run Run Shaw Hospital Zhejiang University School of MedicineHangzhouChina Department of Nephrology Sun Yat-Sen Memorial HospitalSun Yat-Sen UniversityGuangzhouChina The Second People’s Hospital of shenzhen Shenzhen UniversityShenzhenChina Institute of Nephrology Zhongda HospitalSoutheast University School of MedicineNanjingChina Children’s Hospital of Fudan University ShanghaiChina Renal Department and Institute of Nephrology Sichuan Provincial People’s HospitalSchool of MedicineUniversity of Electronic Science and Technology of ChinaSichuan Clinical Research Center for Kidney DiseasesChengduChina Division of Nephrology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanChina Department of Critical Care Medicine Maoming People’s HospitalMaomingChina Key Laboratory of Prevention and Management of Chronic Kidney Disease of Zhanjiang City Institute of NephrologyAffiliated Hospital of Guangdong Medical UniversityZhanjiangChina Huizhou Central People’s Hospital Sun Yat-Sen UniversityHuizhouChina Guizhou Provincial People’s Hospital Guizhou UniversityGuiyangChina Department of Nephrology the First People’s Hospital of FoshanFoshanChina Department of Nephrology Guangdong Provincial Hospital of Chinese Medicinethe Second Affiliated Hospitalthe Second Clinical CollegeGuangzhou University of Chinese Medicin

Early insulin therapy is capable to achieve glycemic control and restoreβ-cell function in newly diagnosed type 2 diabetes(T2D),but its effect on cardiovascular outcomes in these patients remains *** this nationwide real-world study,we analyzed electronic health record data from 19 medical centers across china between 1 January 2000,and 26 May *** included 5424 eligible patients(mean age 56 years,2176 women/3248 men)who were diagnosed T2D within six months and did not have prior cardiovascular *** Cox regression models were used to estimate the associations of early insulin therapy(defined as the first-line therapy for at least two weeks in newly diagnosed T2D patients)with the incidence of major cardiovascular events including coronary heart disease(CHD),stroke,and hospitalization for heart failure(HF).During 17,158 persons years of observation,we documented 834 incident CHD cases,719 stroke cases,and 230 hospitalized cases for *** diagnosed T2D patients who received early insulin therapy,compared with those who did not receive such treatment,had 31%lower risk of incident stroke,and 28%lower risk of hospitalization for *** significant difference in the risk of CHD was *** found similar results when repeating the aforesaid analysis in a propensity-score matched population of 4578 patients and with inverse probability of treatment weighting *** findings suggest that early insulin therapy in newly diagnosed T2D may have cardiovascular benefits by reducing the risk of incident stroke and hospitalization for HF.

关键词： cardiovascular treatment nationwide

A grasp planning algorithm under uneven contact point distribution scenario for space non-cooperative target capture

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Chinese Journal of Aeronautics 2023年第11期36卷 452-464页

作者： bicheng cai Chengfei yue Fan WU Xueqin CHEN Yunhai GENG Research Center of the Satellite Technology Harbin Institute of TechnologyHarbin 150001China Institute of Space Science and Applied Technology Harbin Institute of Technology ShenzhenShenzhen 518055China

The contact point configuration should be carefully chosen to ensure a stable capture,especially for the non-cooperative target capture mission using multi-armed *** this work scenario,the contact points on the base and on the arms are distributed on the opposite side of the ***,large forces will be *** cope with this problem,an uneven-oriented distribution union criterion is *** union criterion contains a virtual symmetrical criterion and a geometry *** virtual symmetrical contact point criterion is derived from the proof of the force closure principle using computational geometry to ensure a stable grasp,and the geometry criterion is calculated by the volume of the minimum polyhedron formed by the contact points to get a wide-range *** further accelerate the optimization rate and enhance the global search ability,a line array modeling method and a continuous-discrete global search algorithm are *** line array modeling method reduces the workload of calculating the descent direction and the gradient available,while the continuous-discrete global search algorithm reducing the optimization *** a highly efficient grasping is achieved and the corresponding contact point is ***,an exhaustive verification is conducted to numerically analyze the disturbance resistance ability,and simulation results demonstrate the effectiveness of the proposed algorithms.

关键词： Grasp planning Line array modeling Space debris removal Space non-cooperative target capture Virtual symmetrical contact point method

Modular crawling robots using soft pneumatic actuators

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Frontiers of Mechanical Engineering 2021年第1期16卷 163-175页

作者： Nianfeng WANG bicheng CHEN Xiandong GE Xianmin ZHANG Wenbin WANG Guangdong Key Laboratory of Precision Equipment and Manufacturing Technology School of Mechanical and Automotive EngineeringSouth China University of TechnologyGuangzhou 510640China School of Mechanical and Electrical Engineering Shenzhen PolytechnicShenzhen 518055China

Crawling robots have elicited much attention in recent years due to their stable and efficient *** this work,several crawling robots are developed using two types of soft pneumatic actuators(SPAs),namely,an axial elongation SPA and a dual bending *** constraining the deformation of the elastomeric chamber,the SPAs realize their prescribed motions,and the deformations subjected to pressures are characterized with numerical *** are performed for verification,and the results show good *** SPAs are fabricated by casting and developed into crawling robots with 3D-printing *** schemes are presented,and crawling tests are *** speeds predicted by the numerical models agree well with the speeds in the experiments.

关键词： soft robot soft pneumatic actuator kinematic model crawling robot modular design

S-scheme heterojunction photocatalysts for CO_(2) conversion: Design, characterization and categories

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Energy Reviews 2023年第4期2卷 63-80页

作者： Aiyun Meng bicheng Zhu Yucun Zhong Shuang Zhou Peigang Han Yaorong Su College of New Materials and New Energies Shenzhen Technology UniversityShenzhenPR China'Laboratory of Solar FuelFaculty of Materials Science and ChemistryChina University of Geosciences68 Jincheng StreetWuhan430078PR China

Photocatalytic CO_(2) conversion into valuable hydrocarbon fuels via solar light is a promising strategy to simul-taneously address energy shortage and environmental ***,the photocatalytic CO_(2) reduction performance is too poor to be practically utilized due to the rapid recombination of photogenerated charge *** step-scheme(S-scheme)heterojunction photocatalysts can facilitate the charge separation and maximize the redox ability,thus remarkably enhancing the photocatalytic CO_(2) reduction *** review summarizes the progress of S-scheme heterojunction photocatalysts applied in the photocatalytic CO_(2) reduction ***,we introduce the fundamental design principles and characterization *** direct and indirect techniques to confirm the S-scheme charge transfer mechanism are ***,we divide S-scheme composite photocatalyst into the following categories depending on their compositions:g-C_(3)N_(4)-based,metal-chalcogenide-based,TiO_(2)-based,bismuth-based,other metal oxide-based and other semiconductor-based S-scheme *** synergistic effect of the S-scheme charge transfer pathway as well as the unique intrinsic properties of semiconductor materials on the photocatalytic CO_(2) reduction performance is discussed in ***,concluding perspectives on the challenges and opportunities for the further exploration of highly efficient S-scheme photocatalysts in photocatalytic CO_(2) conversion are presented.

关键词： Step-scheme heterojunction Photocatalyst CO_(2)reduction Characterization techniques

快速城市化流域全氟化合物的污染特征及生态风险

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北京大学学报（自然科学版） 2019年第3期55卷 543-552页

作者：王之芬梁新秀占笔成吴疆高月许楠深圳市重金属污染控制与资源化重点实验室北京大学深圳研究生院环境与能源学院深圳518055 深圳市龙华区环境保护和水务局深圳518000

为探究快速城市化地区城市河流中全氟化合物(PFCs)的污染特征,于枯水期和丰水期分别采集深圳市观澜河干流的表层水样,通过固相萃取法处理水样,并利用超高效液相色谱–三重四级杆串联质谱(UPLCESI-MS/MS)技术分析11种PFCs的含量。结果表... 详细信息

为探究快速城市化地区城市河流中全氟化合物(PFCs)的污染特征,于枯水期和丰水期分别采集深圳市观澜河干流的表层水样,通过固相萃取法处理水样,并利用超高效液相色谱–三重四级杆串联质谱(UPLCESI-MS/MS)技术分析11种PFCs的含量。结果表明,丰水期和枯水期观澜河干流水体中PFCs的含量分别为179.15～613.68和37.04～103.70 ng/L。其中,全氟己烷磺酸(PFHxS)、全氟丁烷磺酸(PFBS)、全氟己酸(PFHxA)和全氟辛酸(PFOA)是主要污染物。所采集的样品中,丰水期PFCs的浓度高于枯水期,下游采样点PFCs的浓度高于上中游河段。与已报道的其他水体相比,由于流域的快速城市化,观澜河水体的PFCs含量水平较高。生态风险评估表明,水体中检出的PFCs均不会对水体造成生态风险。

关键词：全氟化合物城市河流时空分布来源解析风险评估

Fluxless bonding with silver nanowires aerogel in die-attached interconnection

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china Welding 2023年第2期32卷 32-41页

作者：傅必成方毅张乐李道会齐放宋利军祝温泊 Sauvage Laboratory for Smart Materials School of Materials Science and EngineeringHarbin Institute of Technology(Shenzhen)Shenzhen 518055China china Academy of Space Technology Xi′an 710100China NIO Nanjing 210046China

The electronic product has gravitated towards component miniaturization and integration, employment of lead-free materials, and low-temperature soldering processes. Noble-metal aerogels have drawn increasing attention for high conduction and low density. However,the noble metal aerogels with outstanding solderability were rarely studied. This work has successfully synthesized an aerogel derived from silver nanowires(AgNWs) using a liquid phase reduction method. It is found that the noble metal aerogels can be made into diverse aerogel preformed soldering sheets. The influence of bonding temperature(150-300 ℃), time(2-20 min), and pressure(5-20 MPa) on the joint strength of the AgNWs aerogel affixed to electroless nickel/silver copper plates were investigated. Additionally, the AgNWs aerogel displays almost the same shear strength for substrates of various sizes. In a word, this study presents a flux-free, high-strength, and adaptable soldering structural material.

关键词： silver nanowires aerogel nanostructured materials soldering preform bonding curved surface

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高性能环氧树脂基ECA的制备及机理分析

当代化工研究 2023年第5期 170-172页

作者：赵健岚杨帆傅必成杜智鹏周启航李明雨哈尔滨工业大学(深圳)索维奇智能材料实验室广东518055

电子设备对小型化、高功率密度等要求越来越高,无铅化的提出使人们摒弃了传统的锡铅合金焊料,逐渐将目光转向新型的封装结构和材料,聚合物导电粘合剂又称导电胶(Electrically Conductive Adhesive,ECA),便是其中之一。本文系统地讨论对... 详细信息

电子设备对小型化、高功率密度等要求越来越高,无铅化的提出使人们摒弃了传统的锡铅合金焊料,逐渐将目光转向新型的封装结构和材料,聚合物导电粘合剂又称导电胶(Electrically Conductive Adhesive,ECA),便是其中之一。本文系统地讨论对比了两大类环氧树脂作为基体的ECA性能,制备了一种高强度高导电的环氧树脂基导电银胶作为一种新的封装连接材料并解释了其性能优异的原因,传统聚合物在固化过程中形成的大量孔洞得到有效降低,ECA的电导率和强度从而得到大幅度提高。所制备出的高性能环氧树脂基ECA能够更好的适应封装材料的强度和导电导热需求。

关键词：导电银胶(ECA) 体积电阻率抗剪强度界面张力固化工艺