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A comparative study on the anti-bacterial effect of Echinops persicus, Cardamine uliginosa and Vaccaria oxyodontha Boiss on Staphylococcus aureus and Escherichia coli bacteria in vitro

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TMR Integrative Medicine 2022年第6期6卷 1-7页

作者： Maryam Soori bibi zahra nejad ghaffar Sedighe Soleimani Rahele Bahrami Seyed Hossein Hashemi Hossein Abbaspour Hamid Hashemi-Moghaddam Department of Biochemistry Hamedan BranchIslamic Azad UniversityHamedan 15743-65181Iran Department of Biochemistry Shoushtar BranchIslamic Azad UniversityShoushtar 14778-93855Iran Department of Biology Damghan BranchIslamic Azad UniversityDamghan ***Iran Department of nuclear engineering Olom Tahghighat branchIslamic Azad UniversityTehran ***Iran Department of Chemistry Damghan BranchIslamic Azad UniversityDamghan ***Iran.

Background:Medicinal herbs have always been closely associated with human beings,and no one deny their medicinal effects and *** are over 7,500 plant species in the rich flora of *** study,intends to investigate the anti-bacterial properties of three different plant species from Iranian flora,including Echinops persicus,Cardamine uliginosa,and Vaccaria oxyodontha *** and methods:This cross-sectional study was performed after confirmation and identification of collected *** plants were dried in the shade for *** the methanol extract of these plants was extracted by the classical extraction *** plants’antimicrobial effects of the plants were evaluated by agar disk diffusion,minimum inhibitory concentration,and minimum bactericidal *** mentioned plants’anti-bacterial activity was compared with the antibiotic discs of gentamicin(10 mg)and vancomycin(30 mg).SPSS software v20 was used for data analysis of Kruskal-Wallis and Dunn’s tests(P<0.05).Results:The lowest minimum inhibitory concentration obtained from the methanol extract of Cardamine uliginosa on standard strains of Staphylococcus aureus and Escherichia coli at 15.62 mg/mL for methanol extracts of Echinops persicus and Vaccaria oxyodontha Boiss on *** and *** at 31.25 mg/mL and 125 mg/mL,*** highest diameter of inhibition zone caused by methanol extract of Cardamine uiliginosa was against *** and *** with an inhibition zone of 23.9±0.29 mm and 20.4±0.43 mm,*** with the antibiotics gentamicin and vancomycin,the Cardamine uliginosa showed a stronger inhibitory effect(P<0.05).Conclusion:Echinops persicus,Cardamine uliginosa,and Vaccaria oxyodontha Boiss have anti-bacterial *** anti-bacterial property of Cardamine uilignosa is higher than the other two herbal medicine.

关键词： minimum inhibitory concentration Echinops persicus Cardamine uliginosa Vaccaria oxyodontha Boiss

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