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Smart dental materials for antimicrobial applications

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Bioactive Materials 2023年第6期24卷 1-19页

作者： carolina Montoya Lina Roldan Michelle Yu Sara Valliani Christina ta Maobin Yang Santiago Orrego Department of Oral Health Sciences Kornberg School of DentistryTemple UniversityPhiladelphiaPAUSA Bioengineering Research Group(GIB) Universidad EAFITMedellínColombia Department of Endodontology Kornberg School of DentistryTemple UniversityPhiladelphiaPAUSA Bioengineering Department College of EngineeringTemple UniversityPhiladelphiaPAUSA

Smart biomaterials can sense and react to physiological or external environmental stimuli(e.g.,mechanical,chemical,electrical,or magnetic signals).The last decades have seen exponential growth in the use and development of smart dental biomaterials for antimicrobial applications in *** biomaterial systems offer improved efficacy and controllable bio-functionalities to prevent infections and extend the longevity of dental *** review article presents the current state-of-the-art of design,evaluation,advantages,and limitations of bioactive and stimuli-responsive and autonomous dental materials for antimicrobial ***,the importance and classification of smart biomaterials are ***,the categories of bioresponsive antibacterial dental materials are systematically itemized based on different stimuli,including pH,enzymes,light,magnetic field,and *** each category,their antimicrobial mechanism,applications,and examples are ***,we examined the limitations and obstacles required to develop clinically relevant applications of these appealing technologies.

关键词： Antimicrobial Antibacterial Antifungal Smart dental materials Bioresponsive biomaterials Stimuli-responsive Restorative dentistry Biofilm Antibiofilm Bioactive

Diagnosis of osteoporosis based on multi-scale wavelet parameters of ultrasonic guided waves

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Chinese Journal of Acoustics 2017年第4期36卷 429-438页

作者： SONG Xiaojun ta De'an MOILANEN petro Department of Electronic Science and Technology Shanghai University of Electric Power Department of Electronic Engineering Fudan University Shanghai key Laboratory of Medical Image processing and Computer Assisted Surgery Fudan University Department of physics Jyvaskyla University

Evaluating bone regularly is important to prevent and control the disease of osteoporosis. Impact of osteoporosis on ultrasonic guided waves propagating in human long bones is studied in this paper. Multi-scale wavelet transform is proposed to process the received guided waves, and by analyzing energy changes in detail components of high order wavelet at different propagating distance to assess if osteoporosis happened. The guided waves signals are collected from the tibias of 13 volunteers. Based on the analysis of multi-scale wavelet transform, the high order detail components d6 and d5 changed dramatically with the propagation of ultrasonic guided waves along long bones, which means these 7 volunteers are diagnosed with osteoporosis. Compared with X-ray diagnosis, the effectiveness of this method can reach 92.3% in 13 volunteers. This suggests the multi-scale wavelet transform method is potential in ultrasonic assessment of bone quality.

关键词： osteoporosis wavelet guided ultrasonic bones dramatically regularly propagating transducer cortical

Effect of copper on the degradation of pesticides cypermethrin and cyhalothrin

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Journal of Environmental Sciences 2007年第10期19卷 1235-1238页

作者： LIU Ting-feng SUN Cheng ta Na HONG Jun YANG Shao-gui CHEN Chuan-xiang State Key Laboratory of pollution Control and Resource Reuse School of the Environment Nanjing University Nanfing 210093 China School of Material Science and Engineering Jiangsu University of Scienee and Technology Zhenjiang 212003 China

The influence of coexisting copper （Cu） ion on the degradation of pesticides pyrethroid cypermethrin and cyhalothrin in soil and photodegradation in water system were studied. Serial concentrations of the pesticides with the addition of copper ion were spiked in the soil and incubated for a regular period of time, the analysis of the extracts from the soil was carded out using gas chromatography （GC）. The photodegradation of pyrethroids in water system was conducted under UV irradiation. The effect of Cu^2＋ on the pesticides degradation was measured with half life 00.5） of degradation. It was found that a negative correlation between the degradation of the pyrethroid pesticides in soil and Cu addition was observed. But Cu^2＋ could accelerate photodegradation of the pyrethroids in water. The t0.5 for cyhalothrin extended from 6.7 to 6.8 d while for cypermethrin extended from 8.1 to 10.9 d with the presence of copper ion in soil. As for photodegradation, t0.5 for cyhalothrin reduced from 173.3 to 115.5 min and for cypermethrin from 115.5 to 99.0 min. The results suggested that copper influenced the degradation of the pesticides in soil by affecting the activity of microorganisms. However, it had catalyst tendency for photodegradation in water system. The difference for the degradation efficiency of pyrethroid isomers in soil was also observed. Copper could obviously accelerate the degradation of some special isomers.

关键词： degradation photodegradation copper cypermethrin cyhalothrin

Impact of the fracture on low-order guided waves in long bone

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Chinese Journal of Acoustics 2015年第2期34卷 166-176页

作者： LIU dan XU Kailiang ta De'an Department of Electronic Engineering Fudan University

Using ultrasonic guided waves to assess long bone fractures and fracture healing has become a promising diagnostic issue. But the multimode overlap of the guided waves challenges the quantitative evaluation and clinical application. In the preformed study, in order to simplify the signal interpretation, the low-frequency sinusoidial signals were used to only excite SO and A0 modes in fractured long bones. The amplitudes of SO and A0 modes were numerically analyzed with variation in crack width and fracture angle. Numerical simulation, based on the two-dimension finite-difference time-domain （2D-FDTD） reveals that both SO and A0 amplitudes decrease with the fracture widening. However, the increase in fracture angle gradually enhances the A0 amplitude, while with respect to the SO mode, its amplitude shows a non-monotonic trend to the variation in fracture angle with a turning point around 45°. The amplitude ratio between S0 and A0 can reflect the variations in crack width and fracture angles. The simulation illustrates that ultrasonic guided SO and A0 modes are sensitive to the degree of both vertical and oblique fractures in the long cortical bone. These findings may be helpful for fractures diagnosis and healing evaluation of the long bone.

关键词： Impact of the fracture on low-order guided waves in long bone AO mode

An Ultrasonic Backscatter Instrument for cancellous Bone Evaluation in Neonates

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Engineering 2015年第3期1卷 336-343页

作者： Chengcheng Liu Rong Zhang Ying Li Feng Xu Dean ta Weiqi Wang Department of Electronic Engineering Fudan University Department of Neonatology Children’s Hospital of Fudan University Key Laboratory of Medical Imaging Computing and Computer Assisted Intervention (MICcaI) of Shanghai

Ultrasonic backscatter technique has shown promise as a noninvasive cancellous bone assessment tool. A novel ultrasonic backscatter bone diagnostic （UBBD） instrument and an in vivo application for neonatal bone evaluation are introduced in this study. The UBBD provides several advantages, including noninvasiveness, non- ionizing radiation, portability, and simplicity. In this study, the backscatter signal could be measured within 5 s using the UBBD. Ultrasonic backscatter measurements were performed on 467 neonates （268 males and 199 females） at the left calcaneus. The backscatter signal was measured at a central frequency of 3.5 MHz. The delay （-/-1） and duration （7-2） of the backscatter signal of interest （SOl） were varied, and the apparent integrated backscatter （AIB）, frequency slope of apparent backscatter （FSAB）, zero frequency intercept of apparent backscatter （FIAB）, and spectral centroid shift （SCS） were calculated. The results showed that the SOl selection had a direct influence on cancellous bone evaluation. The AIB and FIAB were positively correlated with the gestational age （｜R｜ up to 0.45, p 〈 0.001） when -/-1 was short （〈 8 μS）, while negative correlations （｜R｜ up to 0.56, p 〈 0.001） were commonly observed for T1 〉 10 IJS. Moderate positive correlations （IRI up to 0.45, p 〈 0.001） were observed for FSAB and SCS with gestational age when 71 was long （〉 10 μs）. The 7-2 mainly introduced fluctuations in the observed correlation coefficients. The moderate correlations observed with UBBD demonstrate the feasibility of using the backscatter signal to evaluate neonatal bone status. This study also proposes an explicit standard for in vivo SOl selection and neonatal cancellous bone assessment.

关键词： ultrasonic backscatter cancellous bone evaluation signal of interest (SOI) backscatter instrument neonatal bone status

phylogenetic placement of bizarre karschiellid earwigs

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Insect Science 2024年第3期31卷 989-992页

作者： petr Kocárek Ivona Horká Vojtěch Bonczek Markéta Kirstová Department of Biology and Ecology University of OstravaOstravaCzech Republic

Dear Editor,Karschiellidae are a mysterious group of earwigs that attract attention not only because of their interesting appearance and unexplained way of life but also mainly due to their unclear *** phylogenetic relationships of karschiellids remain speculative even 120 years since the family was described,above all due to the unavailability of DNA-grade material for molecular phylogenetic *** study includes successfully sequenced representatives of the Karschiellidae for the first time,and a probable evolutionary scheme and natural classification of karschiellids are proposed based on the constructed multigene phylogeny.

关键词： classification. phylogeny evolutionary

Determination of erodible particles on cultivated soils by wind tunnel simulation

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Chinese Science Bulletin 1998年第19期43卷 1646-1651页

作者： Lianyou Liu Jianhua Wang Xiaoyan Li Yuzhang Liu Wanquan ta Haimei peng Chinese Acad Sci Desert Res Inst Lanzhou 730000 Peoples R China Lanzhou Univ Dept Geog Sci Lanzhou 730000 Peoples R China

The erodible particle size distribution, diameter range and separate content of three soils from semi-arid regions of China were determined at different wind velocities through wind tunnel simulation and dry sieving. It was demonstrated that soil erodibility by wind depends not only on the intrinsic soil properties, but also on the extrinsic erosion effect of the erosive winds. It was supposed that there existed general consistency in the mechanics of wind erosion on different soils.

关键词： soil erosion by wind erodible particles particle size distribution.

Subtle traps prediction using sequence stratigraphy and 3D seismic technology: A case study from Qikou depression in Huanghua basin

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Journal of Central South University of Technology 2005年第Z1期12卷 141-145页

作者： MAO Ning-bo daI ta-gen pENG Sheng-lin Key Laboratory of Exploration Technologies for Oil and Gas Resources Ministry of Education Yangtze University Jingzhou 434023 China School of Geoscience and Enviromental Engineering Central South University Changsha 410083 China School of Geoscience and Enviromental Engineering Central South University Changsha 410083 China School of Geoscience and Enviromental Engineering Central South University Changsha 410083 China

Forecasting subtle traps by sequence stratigraphy and 3D seismic data is a sensitive topic in hydrocarbon exploration. Research on subtle traps by geophysical data is the most popular and difficult. Based on the sufficiently drilling data, log data, core data and 3D seismic data, sediment sequence of Qikou depression, Huanghua basin was partitioned by using sequence stratigraphy theory. Each sediment sequence system mode was built. Sediment faces of subtle traps were pointed out. Dominating factors forming subtle traps were analyzed. Sandstone seismic rock physics and its response were studied in Tertiary System. Sandstone geophysical response and elastic modulus vary laws with pressure, temperature, porosity, depth were built. Experimental result and practice shows that it is possible using seismic information forecasting subtle traps. Integrated using geology, log, drilling data, special seismic processing technique, interpretation technique, high precision horizon calibration technique, 3D seismic visualizing interpretation, seismic coherence analysis, attribute analysis, logging-constrained inversion, time frequency analysis, subtle trapsobject is identified and interpreted. Finally, advantage object of subtle trap in this area was determined. Bottomland sand stratigraphic and lithologic reservoirs in Qinan slope zone have been founded by means of high resolution 3D seismic data field technique, high resolution 3D seismic data processing technique and seismic wave impendence inversion technique.

关键词： Huanghua basin sequence stratigraphy subtle trap seismic exploration 3D seismic ultrasonic wave

Virtual Fluorescence Translation for Biological Tissue by Conditional Generative Adversarial Network

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phenomics 2023年第4期3卷 408-420页

作者： Xin Liu Boyi Li Chengcheng Liu Dean ta Academy for Engineering and Technology Fudan UniversityShanghai 200433China State Key Laboratory of Medical Neurobiology Fudan UniversityShanghai 200433China Center for Biomedical Engineering Fudan UniversityShanghai 200433China

Fluorescence labeling and imaging provide an opportunity to observe the structure of biological tissues,playing a crucial role in the field of ***,when labeling and imaging biological tissues,there are still some challenges,e.g.,time-consuming tissue preparation steps,expensive reagents,and signal bias due to *** overcome these limitations,we present a deep-learning-based method for fluorescence translation of tissue sections,which is achieved by conditional generative adversarial network(cGAN).Experimental results from mouse kidney tissues demonstrate that the proposed method can predict the other types of fluorescence images from one raw fluorescence image,and implement the virtual multi-label fluorescent staining by merging the generated different fluorescence images as ***,this proposed method can also effectively reduce the time-consuming and laborious preparation in imaging processes,and further saves the cost and time.

关键词： Virtual fluorescence labeling Image translation Tissues section Generative adversarial network