检索结果-南通市图书馆

Hydroxychloroquine-induced renal phospholipidosis resembling Fabry disease in undifferentiated connective tissue disease: A case report

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2019年第24期7卷 4377-4383页

作者： Song-Zhao Wu xiang Liang Jian Geng Meng-bi Zhang Na Xie xiao-Yan Su Nephrology Department Tungwah Hospital of Sun Yat-Sen UniversityDongguan 523000Guangdong ProvinceChina Department of Pathology School of Basic Medical SciencesSouthern Medical UniversityGuangzhou 510515Guangdong ProvinceChina

BACKGROUND Fabry disease is a kind of lysosomal storage disease resulting from deficient activity of the lysosomal hydrolase alpha-galactosidase A(GLA). A mutation in the GLA gene leads to a loss of activity of alpha-galactosidase A. Some drugs,such as hydroxychloroquine, can cause pathological changes similar to those usually seen in Fabry *** SUMMARY We report the case of a 41-year-old female patient who was diagnosed with undifferentiated connective tissue disease in 2008. Hydroxychloroquine treatment started 2 years ago, and proteinuria and hematuria increased. Renal biopsy demonstrated renal phospholipidosis. Zebra bodies and myelin figures were found by renal electron microscopy and were initially thought to be indicators of Fabry disease. A genetic analysis of the patient and her family members did not reveal mutations in the GLA gene, supporting a diagnosis of hydroxychloroquine-induced renal *** This report reveals one of the adverse effects of hydroxychloroquine. We should pay more attention to hydroxychloroquine-induced renal phospholipidosis.

关键词： Fabry disease Undifferentiated connective tissue disease Hydroxychloroquine Renal phospholipidosis Case report

A Micro-coupling for Micro Mechanical Systems

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Mechanical Engineering 2016年第3期29卷 571-578页

作者： LI Wei ZHOU Zhixiong ZHANG bi xiao Yunya College of Mechanical and Vehicle Engineering Hunan University School of Engineering University of Connecticut

The error motions of micro mechanical systems, such as micro-spindles, increase with the increasing of the rotational speed, which not only decreases the rotational accuracy, but also promotes instability and limits the maximum operational speed. One effective way to deal with it is to use micro-flexible couplings between the drive and driven shafts so as to reduce error motions of the driven shaft. But the conventional couplings, such as diaphragm couplings, elastomeric couplings, bellows couplings, and grooved couplings, etc, cannot be directly used because of their large and complicated structures. This study presents a novel micro-coupling that consists of a flexible coupling and a shape memory alloy（SMA）-based clamp for micro mechanical systems. It is monolithic and can be directly machined from a shaft. The study performs design optimization and provides manufacturing considerations, including thermo-mechanical training of the SMA ring for the desired Two-Way-Shape-Memory effect（TWSMe）. A prototype micro-coupling and a prototype micro-spindle using the proposed coupling are fabricated and tested. The testing results show that the prototype micro-coupling can bear a torque of above 5 N · mm and an axial force of 8.5 N and be fitted with an SMA ring for clamping action at room temperature（15 ℃） and unclamping action below –5 ℃. At the same time, the prototype micro-coupling can work at a rotational speed of above 200 kr/min with the application to a high-speed precision micro-spindle. Moreover, the radial runout error of the artifact, as a substitute for the micro-tool, is less than 3 μm while that of turbine shaft is above 7 μm. It can be concluded that the micro-coupling successfully accommodates misalignment errors of the prototype micro-spindle. This research proposes a micro-coupling which is featured with an SMA ring, and it is designed to clamp two shafts, and has smooth transmission, simple assembly, compact structure, zero-maintenance and balanced motio

关键词： coupling clamp shape memory alloy thermo-mechanical training micro-spindle

Fractional full duplex cellular network: a stochastic geometry approach

在线全文

学校读者我要写书评

暂无评论

Science China(Information Sciences) 2018年第2期61卷 50-64页

作者： Wenping bi Limin xiao Xin SU Shidong ZHOU State Key Laboratory on Microwave and Digital Communications Tsinghua National Laboratory for Information Science and Technology Department of Electronic Engineering Tsinghua University

In-band full-duplex(FD) communication has been considered as a promising technology to enhance the spectral efficiency(SE) for the next generation of wireless system. However, the severe interference in FD cellular network may largely degrade the system performance, especially for cell edge users. In this paper, multi-cell cellular network consisting of BSs with FD capability and legacy half duplex(HD) users is studied. In order to relieve the received interference and enhance the system SE, a new resource allocation strategy named fractional FD(FFD) is proposed and its main idea and procedure are described as ***, the frequency and time resources are partitioned into FD resource blocks(RBs) and HD RBs based on the network topology. Then all the users are classified into two groups named cell center users(CCUs)and cell edge users(CEUs) based on their channel conditions. At last, in each cell, each FD RB is allocated to a pair of CCUs with one in uplink and the other in downlink transmission direction, while only one CEU in the uplink(or downlink) transmission direction is scheduled over each HD RB. Tractable results of both the coverage probabilities and the ergodic rates of FFD, FD and HD systems are derived using stochastic geometry method. Numerical results show that, FFD can significantly improve the coverage probability of all users especially for CEUs compared with FD cellular system, and higher system SE is obtained compared with FD and HD cellular network. With proper design of the classification criterion and under the simulation settings of this paper, the SE of FFD system outperforms FD and HD system by 1.25 and 1.38 times,respectively.

关键词： full duplex half duplex stochastic geometry radio resources allocation small cell

Performance and Kinetics Studies on Selective Catalytic Reduction of NOx with NH_3 over MnO_x-WO_3/TiO_2 Catalyst

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Chemical Research in Chinese Universities 2010年第6期26卷 1002-1006页

作者： WU bi-jun xiao Ping LIU xiao-qin Guodian Science and Technology Research Institute Nanjing 210031 P R. China Chemical Engineering Institute Nanjing University of Technology Nanjing 210009 P. R. China

The catalytic activities of MnOx-WO3/TiO2 for selective catalytic reduction（SCR） of NO with NH3 were investigated in a wide range of temperature and reaction *** yielded a NOx conversion of 80.3%—99.6% and a N2 product selectivity of 100%—98.7% during 100 °C to 350 °C at gas hourly space velocity（GHSV）=18900 *** the presence of 0.01% SO2 and 6% H2O at 120 °C,the NOx conversion can maintain 98.5%.At 300 °C and with 0.07% SO2 in reactant stream,the NOx conversion stabilized at 99% as high as the commercial V-W/TiO2 catalyst＇s *** steady-state kinetics study shows that O2 played a promoting *** the presence of less than 1.5% O2,NOx conversion can increase sharply with the increase of O2 *** reaction order was zero with respect to NH3 and first with respect to NO with excess O2 and *** kinetics active energy（Ea） of Mn-W/TiO2 was calculated to be 6.24 kJ/mol according to the kinetic experiment at various temperatures,much lower than those of other catalysts reported in the ***-W/TiO2 is an excellent catalyst for SCR of NO with NH3 by now.

关键词： Selective catalytic reduction of NO with NH3 MnOx-WO3/TiO2 Performance Kinetics

An unexpected approach to enhance specific surface area and mesopore amount of polyaniline by Zn doping

在线全文

学校读者我要写书评

暂无评论

Rare Metals 2024年第9期43卷 4585-4594页

作者： Zhi-Da Zhu Yu-Zhe Han xiao-bi Jing School of Mechanical Engineering Yangzhou UniversityYangzhou 225127China School of Chemistry and Chemical Engineering Yangzhou UniversityYangzhou 225002China

Poly-p-anisidine could be easily fabricated via the oxidative polymerization reaction of p-anisidine using H_(2)O_(2)as the green *** was unexpectedly found that zinc doping could significantly improve the adsorption ability of the material versus heavy metals such as Pb,Cu,Pd,Ag and *** of nitrogen adsorption–desorption experiments demonstrated that Zn doping could enhance the specific surface area and mesopore amount of the prepared material,which might facilitate its absorption to *** work not only provides a novel material for the treatment of heavy metal-polluted water but also leads to a nice mesoporous catalyst support for environment protection and organic synthesis,*** Zn-doped poly-panisidine can be employed as the catalyst support to prepare Cu@PANI-OMe/Zn or Pd@PANI-OMe/Zn for the oxidative degradation reaction of phenol or Suzuki–Miyaura coupling reactions,*** discloses a new strategy for fabricating the mesoporous polyaniline materials with profound application potential.

关键词： Surfaces Porous materials Rare metal concentration Adsorption Catalysis

Trigger control characteristics of fuze-recoil simulation system based on electromagnetic launcher

在线全文

学校读者我要写书评

暂无评论

Journal of Systems Engineering and Electronics 2017年第3期28卷 563-571页

作者： Wenhao Wang Shihua bi Hongjun xiang Chao Zhan Xichao Yuan School of Aerospace Beijing Institute of TechnologyBeijing 100081China Shijiazhuang Mechanical Engineering College Shijiazhuang 050003China Representative Bureau of the General Equipment Xi’an 710032China

Fuze is the information processing and control unit of the ammunition, so the quality of the fuze becomes one of the most important aspects of ammunition detection. Since using recoil force is a common method to the arm fuze, its dynamic simulation test has always been the focus of the fuze test research. A new fuze recoil environmental simulation method is proposed based on the electromagnetic launcher. Then the trigger control characteristics of the fuze recoil simulation system and the influence of the trigger position on the recoil force are studied. The results of the study show that although the pulse width of the armature force curve can be changed by adjusting the trigger position, due to the limit of the range, there also exists the contradiction that the electromagnetic pulse width gets narrow with the increase of electromagnetic force peak. Thus, it cannot meet the requirements of the fuze launch recoil simulation. In order to make the recoil force close to the actual environment, the multi-stage trigger control characteristics are analyzed, and the influence of trigger position on recoil environmental force characteristics is studied. Then a fuze launch recoil environmental simulation platform is established and continuous electromagnetic force is achieved by using the trigger strategy. Finally, the experiment is performed to simulate the fuze launch recoil environment and show the feasibility and effectiveness of the proposed theoretical analysis. The major research work of this paper includes studying the composition and basic principle of the simulation system, establishing a launch model to analyze the single-stage and multi-stage coil fuze launch recoil characteristics, designing the test device to verify the correctness and validity of the research. This paper draws the conclusions that the feasibility of the fuze launch environmental simulation based on the electromagnetic launcher is verified, the trigger position has a great influence on force p

关键词： trigger control fuze-recoil simulation electromagnetic launcher

Improved delayed detached-eddy simulation of massive separation around triple cylinders

在线全文

学校读者我要写书评

暂无评论

Acta Mechanica Sinica 2015年第6期31卷 799-816页

作者： Zhi-xiang xiao Kun-Yu Luo School of Aerospace Engineering Tsinghua University

The massively separated flow past triple cylin- ders （TriC） in tandem arrangement is simulated using the improved delayed detached-eddy simulation （IDDES） method based on the shear stress transport （SST） model, coupled with the high order adaptive dissipation scheme. The spacing between adjacent cylinders is sub-critical （1.435D）. IDDES prediction of two cylinders （TC） with the same spacing is compared to experimental data for validation, and the numerical results agree well with the available measurements, except for the asymmetry in the gap region. The flow past TriC is investigated using the same method. Generally, the mean flow quantities past TriC, such as the velocity, pressure, and vorticity, are similar to the corresponding components of TC. However, the pressure fluctuations on the TriC surface are uniformly larger than those on TC. Meanwhile, the instantaneous flows past TriC are much more complex. The periodical blockage in the first gap region is found in the TriC case and leads to the up-and-down movement of shear layer in the second gap region.

关键词： Triple cylinders - Massive separation. IDDES ·Hybrid RANS/LES methods

Fe、Ir掺杂MoS_(2)表面对N_(2)气敏吸附与解离反应性能提升的第一性原理研究

在线全文

学校读者我要写书评

暂无评论

原子与分子物理学报 2025年第1期42卷 13-19页

作者：肖香珍胡林峰张建伟河南科技学院新乡453003

基于第一性原理方法,采用周期性平板模型,研究了N_(2)分子在掺杂体系TM-MoS_(2)(TM=Fe、Ir)表面的吸附和解离行为.研究表明:N_(2)分子在TM-MoS_(2)(TM=Fe、Ir)表面吸附能依次为0.62和0.47 eV,而完整MoS_(2)表面的吸附能只有0.08 eV,说... 详细信息

基于第一性原理方法,采用周期性平板模型,研究了N_(2)分子在掺杂体系TM-MoS_(2)(TM=Fe、Ir)表面的吸附和解离行为.研究表明:N_(2)分子在TM-MoS_(2)(TM=Fe、Ir)表面吸附能依次为0.62和0.47 eV,而完整MoS_(2)表面的吸附能只有0.08 eV,说明掺杂之后对N_(2)表现出略好的吸附性能.差分电荷密度分析表明,N_(2)吸附后,掺杂Fe、Ir原子与两个N原子之间电荷有所增加,N-N键之间的区域电荷密度减少,N-N键的强度减弱.态密度计算结果发现,N_(2)在吸附过程中,主要是N原子的2p_(y)、2p_(z)轨道与Ir的5d_(xy)和5d_(z^(2))以及Fe的3d_(xy)和3d_(z^(2))发生杂化作用.通过分析解离活化能,N_(2)在掺杂体系TM-MoS_(2)(TM=Fe、Ir)表面解离需要活化能均较高,且远大于在相应掺杂表面的吸附能,说明N_(2)在掺杂体系TM-MoS_(2)(TM=Fe、Ir)表面解离应该表现为分子吸附或脱附.

关键词： Fe、Ir 掺杂单层MoS_(2) N_(2) 吸附与解离活化能密度泛函理论

维普期刊数据库博看期刊

Optimized LDPC differential-encoded 16QAM scheme for high-speed transmission systems

在线全文

学校读者我要写书评

暂无评论

Journal of Systems Engineering and Electronics 2014年第5期25卷 728-734页

作者： Zhanji Wu xiang Gao Zhiyu xiao School of Information and Communication Engineering Beijing University of Posts and Telecommunications Huawei Technology Limited Corporation

The 16-ary quadrature amplitude modulation （16QAM） is a high spectral efficient scheme for high-speed transmission systems. To remove the phase ambiguity in the coherent detection system, differential-encoded 16QAM （DE-16QAM） is usually used, however, it will cause performance degradation about 3 dB as compared to the conventional 16QAM. To overcome the performance loss, a serial concatenated system with outer low density parity check （LDPC） codes and inner DE-16QAM is proposed. At the receiver, joint iterative differential demodulation and decoding （ID） is carried out to approach the maximum likelihood performance. Moreover, a genetic evolution algorithm based on the extrinsic information transfer chart is proposed to optimize the degree distribution of the outer LDPC codes. Both theoretical analyses and simulation results indicate that this algorithm not only compensates the performance loss, but also obtains a significant performance gain, which is up to 1 dB as compared to the conventional non-DE-16QAM.

关键词： quadrature amplitude modulation (QAM) low density parity check (LDPC) code genetic evolution (GE) algorithm iterative demodulation and decoding (ID) extrinsic information transfer (EXIT) chart.