检索结果-南通市图书馆

Prevalence of polymyxin-induced nephrotoxicity and its predictors in critically ill adult patients:A meta-analysis

World Journal of Clinical Cases 2022年第31期10卷 11466-11485页

作者： Jiang-Lin Wang bi-xiao xiang xiao-Li Song Rui-Man Que xiao-Cong Zuo Yue-Liang Xie Department of Pharmacy The Third Xiangya Hospital of Central South UniversityChangsha 410013Hunan ProvinceChina Department of Pharmacy Sanya Central HospitalSanya 572000Hainan ProvinceChina

BACKGROUND Polymyxin-induced nephrotoxicity is a major safety concern in clinical practice due to long-term adverse outcomes and high *** To conducted a systematic review and meta-analysis of the prevalence and potential predictors of polymyxin-induced nephrotoxicity in adult intensive care unit(ICU)*** PubMed,EMBASE,the Cochrane Library and Reference Citation Analysis database were searched for relevant studies from inception through May 30,*** pooled prevalence of polymyxin-induced nephrotoxicity and pooled risk ratios of associated factors were analysed using a random-effects or fixed-effects model by Stata SE ***,subgroup analyses and meta-regression were conducted to assess *** A total of 89 studies involving 12234 critically ill adult patients were included in the *** overall pooled incidence of polymyxin-induced nephrotoxicity was 34.8%.The pooled prevalence of colistin-induced nephrotoxicity was not higher than that of polymyxin B(PMB)-induced *** subgroup analyses showed that nephrotoxicity was significantly associated with dosing interval,nephrotoxicity criteria,age,publication year,study quality and sample size,which were confirmed in the univariable meta-regression *** was significantly increased when the total daily dose was divided into 2 doses but not 3 or 4 ***,older age,the presence of sepsis or septic shock,hypoalbuminemia,and concomitant vancomycin or vasopressor use were independent risk factors for polymyxin-induced nephrotoxicity,while an elevated baseline glomerular filtration rate was a protective factor against colistin-induced *** Our findings indicated that the incidence of polymyxin-induced nephrotoxicity among ICU patients was *** emphasizes the importance of additional efforts to manage ICU patients receiving polymyxins to decrease the risk of adverse outcomes.

关键词： Polymyxins Nephrotoxicity Critically ill adult patients Risk factors Meta-analysis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

纤维缠绕复合材料弯管线型设计与仿真

引用

玻璃钢／复合材料 2005年第4期 36-38页

作者：田会方肖碧香武汉理工大学武汉430070

根据微分几何建立弯管的圆环面及圆柱面稳定缠绕方程,给出了圆环面的测地线缠绕解及圆柱面的半测地线缠绕解,并提出了用OpenGL及VC++对所设计的线型进行仿真的具体实现办法。

关键词：复合材料纤维缠绕线型弯管仿真

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Observation of acoustic hybrid topological phases induced by the p-d orbital interactions

引用

Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 132-139页

作者： xiao xiang Feng Gao Yu-Gui Peng Peng Wu Zong-Lin Li Xue-Feng Zhu School of Physics and Innovation Institute Huazhong University of Science and Technology

In spinless systems,growing attention has recently been attracted to synthetic gauge fields,which redefine the fundamental crystal symmetries by utilizing the projective algebraic ***,synthetic gauge fields have been commonly investigated in single orbital systems,and explorations on hybrid orbitals remain elusive in ***,we report the experimental observation of hybrid topological phases induced by hybrid synthetic gauge flux,which is formed by the interaction between p and d orbitals embedded in acoustic *** breaking the translation symmetries of Lxand/or Ly,we unambiguously demonstrate the first-order M?bius edge states and higher-order corner *** work establishes a platform for seeking exotic topological phases induced by hybrid-orbitals interactions and initializing the framework of hybrid-orbitalsrelated topological *** applications can be anticipated in scenarios such as high-quality sensing and robust wave trapping due to the stepwise energy distribution of the hybrid topological phase.

关键词： topological insulator synthetic gauge field projective symmetry corner states

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Unlocking the stable interface in aqueous zinc-ion battery with multifunctional xylose-based electrolyte additives

引用

Journal of Energy Chemistry 2025年第1期100卷 770-778页

作者： xiaoqin Li Jian xiang Lu Qiu xiaohan Chen Yinkun Zhao Yujue Wang Qu Yue Taotao Gao Wenlong Liu Dan xiao Zhaoyu Jin Panpan Li Institute for Advanced Study Chengdu University School of Mechanical Engineering Chengdu University College of Food and biological Engineering Chengdu University Institute of Fundamental and Frontier Sciences University of Electronic Science and Technology of China College of Materials Science and Engineering Sichuan University

The growth of dendrites and the side reactions occurring at the Zn anode pose significant challenges to the commercialization of aqueous Zn-ion batteries（AZIBs）. These challenges arise from the inherent conflict between mass transfer and electrochemical kinetics. In this study, we propose the use of a multifunctional electrolyte additive based on the xylose（Xylo） molecule to address these issues by modulating the solvation structure and electrode/electrolyte interface, thereby stabilizing the Zn anode. The introduction of the additive alters the solvation structure, creating steric hindrance that impedes charge transfer and then reduces electrochemical kinetics. Furthermore, in-situ analyses demonstrate that the reconstructed electrode/electrolyte interface facilitates stable and rapid Zn2+ion migration and suppresses corrosion and hydrogen evolution reactions. As a result, symmetric cells incorporating the Xylo additive exhibit significantly enhanced reversibility during the Zn plating/stripping process, with an impressively long lifespan of up to 1986 h, compared to cells using pure ZnSO4electrolyte. When combined with a polyaniline cathode, the full cells demonstrate improved capacity and long-term cyclic stability. This work offers an effective direction for improving the stability of Zn anode via electrolyte design, as well as highperformance AZIBs.

关键词： Solvation

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

纤维缠绕复合材料弯管过程中的运动分析

引用

中国制造业信息化（学术版） 2005年第8期34卷 137-138页

作者：田会方肖碧香武汉理工大学机电学院湖北武汉430070

在确定纤维缠绕复合材料弯管的线型分布的基础上,利用落纱点位置与吐丝嘴位置一一对应的关系,先求解了在机器坐标下的落纱点坐标、悬纱方向矢量,然后建立了悬纱方程,并进一步解出了缠绕机的运动轨迹方程。

关键词：纤维缠绕复合材料弯管运动分析

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

轮毂电动机驱动车辆并联式复合制动策略

引用

江苏大学学报（自然科学版） 2025年第1期46卷 9-17页

作者：付翔肖帅徐超武汉理工大学汽车工程学院湖北武汉430070

基于并联式轮毂电动机驱动实车构型,分析影响制动能量回收效率的主要因素,采用联邦卡尔曼滤波纵向车速估计算法,提出了三层式复合制动控制策略.该策略中的制动决策层根据踏板输入信号和行驶状态来识别制动工况,并进入相应的制动模式.制... 详细信息

基于并联式轮毂电动机驱动实车构型,分析影响制动能量回收效率的主要因素,采用联邦卡尔曼滤波纵向车速估计算法,提出了三层式复合制动控制策略.该策略中的制动决策层根据踏板输入信号和行驶状态来识别制动工况,并进入相应的制动模式.制动控制层根据制动决策层的指令,在常规制动工况下通过粒子群优化(PSO)算法优化前、后轮电制动力矩分配,实现电池有效回收效率最大化;紧急制动工况下,通过模糊自整定PID算法实现车辆在不同附着路面上各轮滑移率的安全有效控制,优化了制动防抱死控制的鲁棒性,提高制动安全性.制动执行层响应制动控制层的指令,设计了电制动补偿机制,以迅速补偿调节各轮轮缸的压力误差,提高车辆制动稳定性.最后实车验证了该复合控制策略的有效性.

关键词：轮毂电动机驱动车辆并联式复合制动粒子群优化制动能量回收模糊自整定PID

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Identification of a dual functional betulinic acid analog for the treatment of osteoarthritis by phenotypic screening

引用

Science China Life Sciences 2025年第1期 300-302页

作者： Ze-Min Lin Mai xiang Wen-Hui Wei Shu-Hui Fan Li Chen Jie Wang xiao-Qian Yang Chun-Hao Yang Shi-Jun He Jian-Ping Zuo Laboratory of Immunopharmacology State Key Laboratory of Drug ResearchShanghai Institute of Materia MedicaChinese Academy of Sciences School of Pharmacy University of Chinese Academy of Sciences School of Pharmacy Nanjing University of Chinese Medicine State Key Laboratory of Drug Research Department of Medicinal ChemistryShanghai Institute of Materia MedicaChinese Academy of Sciences Innovation Research Institute of Traditional Chinese Medicine Shanghai University of Traditional Chinese Medicine Experiment Center for Science and Technology Shanghai University of Traditional Chinese Medicine

Dear Editor, Phenotypic drug discovery, which observes compound effects on physiology,has given way to targeting specific molecules, but has revived by using modern methods to find drugs based on therapeutic outcomes in disease models(Vincent et al., 2022). Osteoarthritis(OA) is a prevalent chronic joint disorder, primarily affecting knee joints, with osteoclast activation due to low-grade inflammation resulting in increased bone resorption and structural changes in the joint(Katz et al.,2021).

关键词：

来源：

同方期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Double [5]carbohelicene: facile synthesis, chiroptical properties,isomerization study, and lasing application

引用

Science China Chemistry 2025年第1期 233-240页

作者： Peipei Liu Yantong Li Meng-xiang Wu Hao Kang xiao-Li Zhao Lin Xu Linlin Liu xiaodong Li Junfeng Fang Zhiwei Fang Ya Cheng Hai-Bo Yang Huakang Yu Xueliang Shi State Key Laboratory of Petroleum Molecular & Process Engineering Shanghai Key Laboratory of Green Chemistry and Chemical ProcessesSchool of Chemistry and Molecular Engineering East China Normal University School of Physics and Optoelectronics South China University of Technology Institute of Polymer Optoelectronic Materials & Devices State Key Laboratory of Luminescent Materials & Devices South China University of Technology School of Physics and Electronic Science Engineering Research Center of Nanophotonics & Advanced Instrument Ministry of EducationEast China Normal University State Key Laboratory of Precision Spectroscopy School of Physics and Electronic Science East China Normal University

Double carbohelicenes have attracted considerable attention due to their aesthetic structures, distinct π-conjugation extension, inherent chirality, and intriguing optical and electronic properties. Herein, the concise de novo synthesis of a new double[5]carbohelicene 1 together with its chiroptical properties, isomerization process and lasing application is presented. 1 was synthesized by a simple protocol involving the formation of a 6,6′-bipentacene as the key intermediate. It is worth noting that1 existed as two diastereomers 1-PP/MM and 1-PM, which were successfully isolated and unambiguously confirmed by Xray crystallography. The optical resolution of the racemic 1-PP/MM was successfully achieved by chiral-phase highperformance liquid chromatography（HPLC）, and 1-PP and 1-MM were characterized by circular dichroism. Interestingly, it was found that 1-PP/MM could be completely isomerized to 1-PM upon heating, and the detailed thermodynamics and kinetics of the isomerization process were systematically investigated. 1-PM exhibited deep-red luminescence with emission maximum at 723 nm and fluorescence quantum yield as high as 32.95%. Consequently, we can showcase the lasing application of 1-PM by doping with epoxy resin to assemble a bottle microlaser spontaneously, which the lasing wavelength is 796.6 nm at a threshold of 0.8 m J cm-2. We believe that our studies, including the facile synthesis methodology, detailed isomerization studies, and lasing application, will shed some light on the design and synthesis of novel carbohelical systems with more functions.

关键词：

来源：

同方期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Pulse signal detection in cognitive UWB system

引用

The Journal of China Universities of Posts and Telecommunications 2012年第3期19卷 74-79页

作者： SONG xiao-ou xiang Xin bi Du-yan DENG Yong Engineering College Air Force Engineering.UniversityXi'an 710038China

According to the problem of cognitive ultra wide-band （UWB） spectrum sensing, a novel UWB pulse signal detection algorithm based on cumulative sum （CUSUM） test is proposed in this paper. Based on the analysis of the existing spectrum sensing schemes for cognitive UWB system, some obvious facts are obtained that it is difficult to detect UWB pulse signal with conventional spectrum sensing schemes, due to its low average signal to noise ratio （SNR）, large bandwidth, and low duty ratio. In this paper the detection algorithm of signal distribution change, which is application of CUSUM test, is considered to be applied to cognitive UWB spectrum sensing. But CUSUM test request that the pre-change and the post-change distributions are i.i.d, which cannot be satisfied in the detection process of UWB pulse signal. Since there are two time domain descriptions on UWB pulse signal, namely one contains only noise and the other one contains pulse signal plus noise, the existing detection algorithm of signal distribution change cannot be directly applied to detect UWB pulse signal. Hence the uniform probability density function expression of UWB pulse signal is first deduced, then CUSUM test is applied to cognitive UWB spectrum sensing. The proposed algorithm is a time sequential detection algorithm, with low complexity and minimal detection delay, which is suitable to detect the low duty ratio signal. Its performance is evaluated through theoretical analysis and numerical simulations. It is shown that this algorithm outperforms the conventional energy detection algorithm and conquers SNR wall phenomenon.

关键词： cognitive UWB (CUWB) spectrum sensing pulse signal CUSUM

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Classification-based self-adaptive differential evolution and its application in multi-lateral multi-issue negotiation

引用

Frontiers of Computer Science 2012年第4期6卷 442-461页

作者： xiaojun bi Jing xiao School of Information and Communication Engineering Harbin Engineering UniversityHarbin 150001China School of Information Engineering Liaoning Provincial College of CommunicationsShenyang 110122China

Multi-lateral multi-issue negotiations are the most complex realistic negotiation problems. Automated ap- proaches have proven particularly promising for complex ne- gotiations and previous research indicates evolutionary com- putation could be useful for such complex systems. To im- prove the efficiency of realistic multi-lateral multi-issue ne- gotiations and avoid the requirement of complete informa- tion about negotiators, a novel negotiation model based on art improved evolutionary algorithm p-ADE is proposed. The new model includes a new multi-agent negotiation protocol and strategy which utilize p-ADE to improve the negotia- tion efficiency by generating more acceptable solutions with stronger suitability for all the participants. Where p-ADE is improved based on the well-known differential evolution （DE）, in which a new classification-based mutation strategy DE/rand-to-best/pbest as well as a dynamic self-adaptive pa- rameter setting strategy are proposed. Experimental results confirm the superiority of p-ADE over several state-of-the-art evolutionary optimizers. In addition, the p-ADE based multi- agent negotiation model shows good performance in solving realistic multi-lateral multi-issue negotiations.

关键词： differential evolution global optimum e-commerce agent multi-lateral multi-issue negotiation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：