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Evaluation of the efficacy and safety of endoscopic band ligation in the treatment of bleeding from mild to moderate gastric varices type 1

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World Journal of Gastroenterology 2024年第5期30卷 440-449页

作者： Yue deng Ya Jiang Tong Jiang Ling chen Hai-Jun Mou bi-Guang Tuo Guo-Qing Shi department of Gastroenterology Digestive Disease HospitalThe Affiliated Hospital of Zunyi Medical UniversityZunyi 563000Guizhou ProvinceChina department of Gastroenterology Guizhou Hospital of the First Affiliated HospitalSun Yat-sen UniversityGuiyang 550000Guizhou ProvinceChina department of Gastroenterology Yinjiang Autonomous County People’s HospitalTongren 554300Guizhou ProvinceChina

BACKGROUND According to practice guidelines,endoscopic band ligation(EBL)and endoscopic tissue adhesive injection(TAI)are recommended for treating bleeding from esophagogastric ***,EBL and TAI are known to cause serious complications,such as hemorrhage from dislodged ligature rings caused by EBL and hemorrhage from operation-related ulcers resulting from ***,the optimal therapy for mild to moderate type 1 gastric variceal hemorrhage(GOV1)has not been ***,the aim of this study was to discover an individualized treatment for mild to moderate *** To compare the efficacy,safety and costs of EBL and TAI for the treatment of mild and moderate *** A clinical analysis of the data retrieved from patients with mild or moderate GOV1 gastric varices who were treated under endoscopy was also *** were allocated to an EBL group or an endoscopic TAI *** differences in the incidence of varicose relief,operative time,operation success rate,mortality rate within 6 wk,rebleeding rate,6-wk operation-related ulcer healing rate,complication rate and average operation cost were compared between the two groups of *** The total effective rate of the two treatments was similar,but the efficacy of EBL(66.7%)was markedly better than that of TAI(39.2%)(Pdelayed postoperative rebleeding in the EBL group was significantly lower than that in the TAI group(11.8%vs 45.1%)(Pdence of postoperative complications in the two groups was *** average cost and other related economic factors were g

关键词： Gastric varices Type 1 gastric variceal hemorrhage Endoscopic band ligation Tissue adhesive injection

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Contribution to the knowledge of the ladybird beetle genus Diomus Mulsant(Coleoptera: Coccinellidae), with description of a new species from China

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Zoological Systematics 2024年第4期 320-330页

作者： Keke bi Xinyue Liang Feng Peng Lizhi Huo Xiaosheng chen Guangzhou Collaborative Innovation Center on Science-Tech of Ecology and Landscape Guangzhou Institute of Forestry and Landscape Architecture department of Forest Protection College of Forestry and Landscape Architecture South China Agricultural University Engineering Research Center of biological Control Ministry of Education

The genus Diomus Mulsant, 1850(Coleoptera: Coccinellidae: Diomini) from China is herein revised. Five species of Diomus are occurring in the Chinese fauna to date, including a new species from the Dafushan Mountains Forest Park, Guangzhou, Guangdong, namely *** bi, Peng & chen, sp. nov. Nomenclatural history, diagnosis, illustrations and distribution were provided for each species. A key to the native species of Diomus from China is also presented.

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Longitudinal gut fungal alterations and potential fungal biomarkers for the progression of primary liver disease

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Science China(Life Sciences) 2024年第6期67卷 1183-1198页

作者： Shiman Jiang Lvwan Xu Yanfei chen Zheyue Shu Longxian Lv Yuxi Zhao Kefan bi Sisi Yang Qiangqiang Wang Lanjuan Li State Key Laboratory for Diagnosis and Treatment of Infectious Diseases National Clinical Research Center for Infectious DiseasesNational Medical Center for Infectious DiseasesCollaborative Innovation Center for Diagnosis and Treatment of Infectious DiseasesThe First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China Division of Hepatobiliary and Pancreatic Surgery Department of SurgeryThe First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China

Liver disease,a major health concern worldwide,is a serious and progressive ***,we not only established a mouse model of deN+CCl4-induced primary liver disease but also collected clinical human samples to investigate longitudinal alterations in the gut *** liver disease advanced,gut integrity was disrupted,and the mycobiota was disturbed in the mouse *** metabolites associated with hepatocellular carcinoma(HCC)differed from those associated with the cirrhotic phase as follows:levels of stercobilin and aflatoxin B1 dialcohol were reduced,while levels of triterpenoids,bafilomycin A1,and DHEA were increased in the HCC *** abundance of the phylum Chytridiomycota increased as the chronic liver disease progressed and was then replaced by the phylum Ascomycota in *** on the results from clinical human samples,the genus Candida(Ascomycota)(in humans)and the genus Kazachstania(Ascomycota)(in mice)occupied a dominant position in the HCC group,while other fungi were *** increased abundance of *** and depletion of *** may be hallmarks of the progression of liver cirrhosis to early ***,the administration of *** and *** in the LC-HCC progression could accelerate or retard the progression of ***,gut fungi have the potential to serve as a noninvasive clinical biomarker and even a treatment method.

关键词： gut mycobiome liver disease longitudinal studies hepatocarcinogenesis fungal biomarker

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An assessment of the CMIP6 performance in simulating Arctic sea ice volume flux via Fram Strait

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Advances in Climate Change Research 2024年第4期15卷 584-595页

作者： Hui-Yan KUANG Shao-Zhe SUN Yu-Fang YE Shao-Yin WANG Hai-Bo bi Zhuo-Qi chen Xiao chenG School of Geospatial Engineering and Science Sun Yat-sen UniversitySouthern Marine Science and Engineering Guangdong Laboratory(Zhuhai)Zhuhai 519082China Key Laboratory of Comprehensive Observation of Polar Environment(Sun Yat-sen University) Ministry of EducationZhuhai 519082China CAS Key Laboratory of Marine Geology and Environment Institute of OceanologyChinese Academy of Sciences(CAS)Qingdao 266071China Laboratory for Marine Geology Qingdao National Laboratory for Marine Science and Technology Qingdao 266237China

Numerical models serve as an essential tool to investigate the causes and effects of Arctic sea ice *** the simulation capabilities of the most recent CMIP6 models in sea ice volume flux provides references for model applications and ***,reliable long-term simulation results of the ice volume fux contribute to a deeper understanding of the sea ice response to global climate *** this study,the sea ice volume flux through six Arctic gateways over the past four decades(1979-2014)were estimated in combination of satellite observations of sea ice concentration(SIC)and sea ice motion(SIM)as well as the Pan-Arctic Ice-Ocean Modeling and Assimilation System(PIOMAS)reanalysis sea ice thickness(SIT)*** simulation capability of 17 CMIP6 historical models for the volume flux through Fram Strait were quantitatively *** ice volume flux simulated from the ensemble mean of 17 CMIP6 models demonstrates better performance than that from the individual model,yet IPSL-CM6A-LR and EC-Earth3-Veg-LR outperform the ensemble mean in the annual volume flux,with Taylor scores of 0.86 and 0.50,***6 models display relatively robust capability in simulating the seasonal variations of volume *** them,CESM2-WACCM performs the best,with a correlation coefficient of 0.96 and a Taylor score of ***,NESM3 demonstrates the largest devi-ation from the observation/reanalysis data,with the lowest Taylor score of *** variability of sea ice volume flux is primarily influenced by SIM and SIT,followed by *** extreme large sea ice export through Fram Strait is linked to the occurrence of anomalously low air temperatures,which in turn promote increased SIC and SIT in the corresponding ***,the intensified activity of Arctic cyclones and Arctic dipole anomaly could boost the southward sea ice velocity through Fram Strait,which further enhance the sea ice outflow.

关键词： Sea ice volume flux CMIP6 models Fram Strait Attribution analysis

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Observation of therapeutic effect of lamp irradiation combined with purple gromwell oil gauze on alleviating intestinal colic in patients

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World Journal of Gastrointestinal Surgery 2024年第6期16卷 1749-1755页

作者： bi-Zhi Cen Yin-Song chen Li-Ping Li Jing-Wen Wu Yan-Fen Xie department of Tumor Center Foshan Hospital of Traditional Chinese MedicineFoshan 528000Guangdong ProvinceChina

BACKGROUND Intestinal colic is a common complication in patients who have undergone radical surgery for colorectal *** Chinese medicine has advantages,including safety and stability,for the treatment of intestinal *** irra-diation for abdominal ironing has been applied in the treatment of many gas-trointestinal *** gromwell oil has the effects of clearing heat,cooling blood,reducing swelling,and relieving *** The general effective rate in the observation group was 95.00%,which was significantly higher than that in the control group(86.67%,P0.05).After 1,2,3,and 4 d of treatment,the duration of symptoms in both groups were decreased,and the duration in the observation group was significantly lower than that in the control group(96.54±9.57 vs 110.45±11.23,87.26±12.07 vs 104.44±11.68,80.45±16.21 vs 99.44±14.95,73.18±15.58 vs 92.17±14.20;Pdecreased,and the NRS scores in the observation group were significantly lower than those in the control group(3.56±0.41 vs 4.04±0.58,3.07±0.67 vs 3.74±1.02,2.52±0.76 vs 3.43±0.85,2.03±0.58 vs 3.03±0.82;P0.05).CONCLUSION The use of lamp irradiation combined with purple gromwell oil gauze in patients with intestinal colic after radical surgery for colorectal cancer can reduce symptom duration,alleviate intestinal colic,and improve treatment efficacy,and this approach is *** is worth promoting the use of this treatment in clinical practice.

关键词： Lamp irradiation Purple gromwell oil gauze Intestinal colic Radical surgery for colorectal cancer Therapeutic effect

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Transplantation of human placental chorionic plate-derived mesenchymal stem cells for repair of neurological damage in neonatal hypoxic-ischemic encephalopathy

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Neural Regeneration Research 2024年第9期19卷 2027-2035页

作者： Lulu Xue Ruolan Du Ning bi Qiuxia Xiao Yifei Sun Ruize Niu Yaxin Tan Li chen Jia Liu Tinghua Wang Liulin Xiong Transformation Research Laboratory The Affiliated Hospital of Zunyi Medical UniversityZunyiGuizhou ProvinceChina State Key Laboratory of biotherapy Sichuan UniversityChengduSichuan ProvinceChina Institute of Neurological Disease Translational Neuroscience CenterWest China HospitalSichuan UniversityChengduSichuan ProvinceChina department of Animal Zoology Institute of NeuroscienceKunming Medical UniversityKunmingYunnan ProvinceChina department of Anesthesiology The Affiliated Hospital of Zunyi Medical UniversityZunyiGuizhou ProvinceChina department of Pediatrics the People’s Liberation Army Rocket Force Characteristic Medical CenterBeijingChina

Neonatal hypoxic-ischemic encephalopathy is often associated with permanent cerebral palsy,neurosensory impairments,and cognitive deficits,and there is no effective treatment for complications related to hypoxic-ischemic *** therapeutic potential of human placental chorionic plate-derived mesenchymal stem cells for various diseases has been ***,the potential use of human placental chorionic plate-derived mesenchymal stem cells for the treatment of neonatal hypoxic-ischemic encephalopathy has not yet been *** this study,we injected human placental chorionic plate-derived mesenchymal stem cells into the lateral ventricle of a neonatal hypoxic-ischemic encephalopathy rat model and observed significant improvements in both cognitive and motor *** chip analysis showed that interleukin-3 expression was significantly elevated in neonatal hypoxic-ischemic encephalopathy model *** transplantation of human placental chorionic plate-derived mesenchymal stem cells,interleukin-3 expression was *** further investigate the role of interleukin-3 in neonatal hypoxic-ischemic encephalopathy,we established an in vitro SH-SY5Y cell model of hypoxic-ischemic injury through oxygen-glucose deprivation and silenced interleukin-3 expression using small interfering *** found that the activity and proliferation of SH-SY5Y cells subjected to oxygen-glucose deprivation were further suppressed by interleukin-3 ***,interleukin-3 knockout exacerbated neuronal damage and cognitive and motor function impairment in rat models of hypoxic-ischemic *** findings suggest that transplantation of hpcMSCs ameliorated behavioral impairments in a rat model of hypoxic-ischemic encephalopathy,and this effect was mediated by interleukin-3-dependent neurological function.

关键词： behavioral evaluations gene knockout human neuroblastoma cells(SH-SY5Y) human placental chorionic derived mesenchymal stem cells interleukin-3 neonatal hypoxic-ischemic encephalopathy nerve injury oxygen-glucose deprivation protein chip small interfering RNA

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A three-way electrolyte with ternary solvents for high-energy-density and long-cycling lithium-sulfur pouch cells

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SusMat 2024年第2期4卷 1-12页

作者： Zheng Li Legeng Yu chen-Xi bi Xi-Yao Li JinMa Xiang chen Xue-Qiang Zhang Aibing chen Haoting chen Zuoru Zhang Li-Zhen Fan Bo-Quan Li cheng Tang Qiang Zhang Tsinghua Center for Green Chemical Engineering Electrification Beijing Key Laboratory of Green Chemical Reaction Engineering and TechnologyDepartment of Chemical EngineeringTsinghua UniversityBeijingChina School of Materials Science and Engineering Beijing Institute of TechnologyBeijingChina Institute of Advanced Materials and Technology University of Science and TechnologyBeijingChina Shanxi Research Institute for Clean Energy Tsinghua UniversityTaiyuanChina Center for Next-Generation Energy Materials and School of Chemical Engineering Sungkyunkwan UniversityJangan-GuSuwon-SiGyeonggi-DoRepublic of Korea College of Chemical and Pharmaceutical Engineering Hebei University of Science and TechnologyShijiazhuangChina Ordos Carbon Neutral Research and Application Co. Ltd.Kangbashi DistrictOrdos CityInner MongoliaChina Institute for Carbon Neutrality Tsinghua UniversityBeijingChina

Lithium–sulfur(Li–S)batteries promise high-energy-density potential to exceed the commercialized lithiumion batteries but suffer from limited cycling lifespan due to the side reactions between lithium polysulfides(LiPSs)and Li metal ***,a three-way electrolyte with ternary solvents is proposed to enable high-energy-density and long-cycling Li–S pouch ***,ternary solvents composed of 1,2-dimethoxyethane,di-isopropyl sulfide,and 1,3,5-trioxane are employed to guarantee smooth cathode kinetics,inhibit the parasitic reactions,and construct a robust solid electrolyte interphase,*** cycling lifespan of Li–S coin cells with 50μm Li anodes and 4.0 mg cm^(−2) sulfur cathodes is prolonged from88 to 222 cycles using the three-way ***-heterogeneous solvation structure of LiPSs and organic-rich solid electrolyte interphase are identified to improve the cycling stability of Li metal ***,a 3.0 Ah-level Li–S pouch cell with the three-way electrolyte realizes a high energy density of 405 Wh kg^(−1) and undergoes 27 *** affords a three-way electrolyte recipe for suppressing the side reactions of LiPSs and inspires rational electrolyte design for practical high-energy-density and long-cycling Li–S batteries.

关键词： lithium metal anodes lithium-sulfur batteries pouch cells solid electrolyte interphase three-way electrolyte

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A review of classical hydrogen isotopes storage materials

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Materials Reports(Energy) 2024年第1期4卷 23-42页

作者： Yang Liu Zhiyi Yang Panpan Zhou Xuezhang Xiao Jiacheng Qi Jiapeng bi Xu Huang Huaqin Kou Lixin chen State Key Laboratory of Silicon and Advanced Semiconductor Materials School of Materials Science and EngineeringZhejiang UniversityHangzhou310027ZhejiangPR China Key Laboratory of Advanced Materials and Applications for Batteries of Zhejiang Province Hangzhou310013ZhejiangPR China Institute of Materials China Academy of Engineering PhysicsMianyang621907SichuanPR China

Hydrogen storage alloys(HSAs)are attracting widespread interest in the nuclear industry because of the generation of stable metal hydrides after tritium absorption,thus effectively preventing the leakage of radioactive *** used HSAs in the hydrogen isotopes field are Zr2M(M=Co,Ni,Fe)alloys,metallic Pd,depleted U,and ZrCo ***,Zr2M(M=Co,Ni,Fe)alloys are considered promising tritium-getter materials,and metallic Pd is utilized to separate and purify hydrogen ***,depleted U and ZrCo alloy are well suited for storing and delivering hydrogen ***,all the aforementioned HSAs need to modulate their hydrogen storage properties for complex operating *** this review,we present a comprehensive overview of the reported modification methods applied to the above *** is an effective amelioration method that mainly modulates the properties of HSAs by altering their local geometrical/electronic ***,microstructural modifications such as nano-sizing and nanopores have been used to increase the specific surface area and active sites of metallic Pd and ZrCo alloys for enhancing de-/hydrogenation *** combination of metallic Pd with support materials can significantly reduce the cost and enhance the pulverization ***,the poisoning resistance of ZrCo alloy is improved by constructing active surfaces with selective ***,the review is constructive for better understanding the properties and mechanisms of hydrogen isotope storage alloys and provides effective guidance for future modification research.

关键词： Hydrogen isotopes storage alloys Alloying Microstructural modification Surface modification Composite materials

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Bronchobiliary fistula in a patient with liver cancer

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Hepatobiliary & Pancreatic Diseases International 2024年第5期23卷 523-525页

作者： Yao-Xin chen Zhi-Hua deng Hao Zhao bi-Ying Zhou Jing-Jing Guo Gang Zeng Jin-Xian Qian department of Respiratory and Critical Care Medicine Suzhou Municipal Hospital Affiliated to Nanjing Medical UniversitySuzhou 215000China

Bronchobiliary fistula(BBF) is a pathologic channel between the biliary tract and bronchial tree. In general, congenital BBF is relatively rare in adult patients. There are a few case reports suggesting that BBF is mainly secondary to hepatobiliary diseases, such as biliary obstruction, tumor, surgery, or liver abscess, and liver tumor is the predominant causative factor [1]. In addition, with the increasing number of liver and biliary surgeries and interventional therapies in recent years, more cases of BBF were reported as a postoperative complication [ 2, 3 ]. In this case, we presented a patient who underwent interventional treatment for liver tumor and was treated for his respiratory symptoms but diagnosed with BBF finally. Here, we summarized the clinical features and main diagnostic procedures of the case, aiming to provide evidence for early identification and diagnosis of BBF.

关键词： biliary fistula diagnosis

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Ecological Discourse Analysis Based on the Corpus-A Case Study on the Environmental Discourse of 21st Century

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Journal of Literature and Art Studies 2024年第8期14卷 693-702页

作者： chen Yuang ZHI Yong-bi School of Foreign Languages and Literature Suzhou University of Science and TechnologyChina

Language learning materials not only provide language input for learners but also subtly disseminate ideology and influence readers’*** study,based on the framework of ecological discourse analysis,quantitatively analyzes and qualitatively describes the ecological significance of environmental texts in the 21st *** aim is to provide references for the compilation of environmental discourse in language learning materials,promote the construction of more ecologically beneficial discourse,and facilitate the widespread dissemination of the ecological philosophy of“Diversity and Harmony,Interaction and Co-existence”among young *** initial findings of this study are as follows:In the environmental texts of the publication,a large number of relational processes and action processes are used to objectively represent the natural environment;the discourse tends to be ambiguous and beneficial,generally aligning with the ecological philosophy of“Diversity and Harmony,Interaction and Co-existence.”This can guide readers to correctly understand and face environmental issues,which is conducive to the healthy development of natural ecosystems.

关键词： 21st Century ecological discourse analysis ecological orientation a corpus-based study

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