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透光混凝土的性能及发展综述

应用化工 2024年第3期53卷 735-738页

作者：韩莹刘恩庞超帅毕学琴翟君宇吉林建筑大学材料科学与工程学院吉林长春130119 吉林省蛟河市漂河镇人民政府吉林蛟河132513

对用于透光混凝土(LTC)的半透明材料的类型及应用进行了综述。基于力学性能、物理性能、透光性能、耐久性能以及微观结构分析等方面对LTC进行了评价。分析讨论了LTC的成本。并对其未来的发展方向进行了展望。

关键词：透光混凝土性能发展综述

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针刺治疗癌痛:从临床证据到科学研究

World Journal of Acupuncture-Moxibustion 2024年第1期34卷 74-75页

作者：何怡瀚张海波毕明刚广东省中医院/广州中医药大学第二临床医学院广州510120 国家自然科学基金委员会北京100085

The increase in cancer incidence and survival rate poses an urgent demand on palliative care and symptom management for cancer *** Chinese medicine(TCM)such as herbal medicine and acupuncture have been widely used in ... 详细信息

关键词：临床证据 acupuncture herbal

Application of a Neural Network to Store and Compute the Optical Properties of Non-Spherical Particles

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Advances in Atmospheric Sciences 2022年第12期39卷 2024-2039页

作者： Jinhe YU Lei bi Wei {1. Xiaoye Z{1.G Key Laboratory of Geoscience big Data and Deep Resource of Zhejiang Province School of Earth SciencesZhejiang UniversityHangzhou 310027China Center for Earth System Modeling and Prediction China Meteorological AdministrationBeijing 100081China Numerical Weather Prediction Center China Meteorological AdministrationBeijing 100081China Key Laboratory of Atmospheric Chemistry of China Meteorological Administration Institute of Atmospheric CompositionChinese Academy of Meteorological SciencesBeijing 100081China

Radiative transfer simulations and remote sensing studies fundamentally require accurate and efficient computation of the optical properties of non-spherical *** paper proposes a deep learning(DL)scheme in conjunction with an optical property database to achieve this *** neural network(DNN)architectures were obtained from a dataset of the optical properties of super-spheroids with extensive shape parameters,size parameters,and refractive *** dataset was computed through the invariant imbedding T-matrix *** separate DNN architectures were created to compute the extinction efficiency factor,single-scattering albedo,asymmetry factor,and phase *** criterion for designing these neural networks was the achievement of the highest prediction accuracy with minimal DNN *** numerical results demonstrate that the determination coefficients are greater than 0.999 between the prediction values from the neural networks and the truth values from the database,which indicates that the DNN can reproduce the optical properties in the dataset with high *** addition,the DNN model can robustly predict the optical properties of particles with high accuracy for shape parameters or refractive indices that are unavailable in the ***,the ratio of the database size(~1.7 GB)to that of the DNN parameters(~20 MB)is approximately 681.,implying that the DNN model can be treated as a highly compressed database that can be used as an alternative to the original database for real-time computing of the optical properties of non-spherical particles in radiative transfer and atmospheric models.

关键词： non-spherical particles light scattering super-spheroid model deep learning neural network

Synthesis and Characterization of CdSe Nanocrystals Capped by CdS

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Chemical Research in Chinese Universities 2003年第3期19卷 269-274页

作者： SUXing-guang LINZhang-{1. HUHai ZhanGJia-hua JINQin-han LaboratoryofExcitedStateProcesses ChineseAcademyofSciencesChangchun130021P.R.China CollegeofChemistry JilinUniversityChangchun130023P.R.China CollegeofChemistry JilinUniversityChangchun130023P.R.China LaboratoryofExcitedStateProcesses ChineseAcademyofSciencesChangchun130021P.R.China

CdSe semiconductor nanocrystals capped by CdS were synthesized in the aqueous solution with 2 mercaptoethanol as the sta{1.lizer. The CdS capping with a higher band gap than that of the core crystallite has successfully eliminated the surface traps. Optical absorption and fluorescence emission spectra were used to probe the effect of CdS passivation on the electronic structure of the nanocrystals. The composite CdSe/CdS nanocrystals exhi{1.t strong, narrow(FWHM≤40 nm) and stable band edge photoluminescence. X ray powder diffraction, transmission electron microscopy and X ray photoelectron spectroscopy were used to analyze the composite nanocrystals and determine their average size, size distribution, shape, internal structure and elemental composition.

关键词： CdSe/CdS Nanocrystal Synthesis Characterization

Structural Characteristics and Influencing Factors of Carbon Emission Spatial Association Network: A Case Study of Yangtze River Delta City Cluster, China

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基于网络药理学及体外实验探究温下方正丁醇部位联合吉非替尼治疗非小细胞肺癌的作用机制

中国地理科学（英文版） 2024年第4期 689页

作者： bi Xi SUN Renjin HU Dongou SHI Hongling Z{1.G {1.

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中国中药杂志 2024年第2期49卷 471-486页

作者：陈瑞杰毕倩宇施杰民钟婧韩晋涛季旭明湖州市中心医院浙江湖州313000 浙江中医药大学基础医学院浙江杭州310053 浙江省神经药理学与转化研究重点实验室浙江杭州310053 浙江中医药大学中医药科学院浙江杭州310053

运用网络药理学、分子对接和体外实验探究温下方正丁醇部位(n-butanol fraction of Wenxia Formula,NWXF)联合吉非替尼(gefitinib,GEF)治疗非小细胞肺癌(non-small cell lung cancer,NSCLC)的潜在作用机制。超高效液相色谱-四极杆-静电... 详细信息

运用网络药理学、分子对接和体外实验探究温下方正丁醇部位(n-butanol fraction of Wenxia Formula,NWXF)联合吉非替尼(gefitinib,GEF)治疗非小细胞肺癌(non-small cell lung cancer,NSCLC)的潜在作用机制。超高效液相色谱-四极杆-静电场轨道阱高分辨质谱法(UPLC-Q-Orbitrap MS)检测NWXF的主要化学成分,利用SwissADME数据库筛选NWXF的活性成分,SwissTargetPrediction数据库获取NWXF活性成分的潜在作用靶点,OMIM和GeneCards数据库搜集NSCLC相关疾病靶点。运用Cytoscape 3.9.0软件和STRING数据库对共同靶点进行蛋白-蛋白互作(protein-protein interaction,PPI)网络构建和关键靶点筛选,利用DAVID数据库进行基因本体论(Gene Ontology,GO)和京都基因与基因组百科全书(Kyoto Encyclopedia of Genes and Genomes,KEGG)富集分析,预测其可能的作用机制。运用SYBYL-X 2.0软件对核心成分与关键靶点进行分子对接验证。MTT法检测NWXF和GEF单用及联用对人非小细胞肺癌细胞(A549、PC-9)增殖的抑制作用以及NWXF对人胚肺成纤维细胞MRC-5的作用,运用Q值评价两药联用的效果,TUNEL法检测NWXF和GEF单用及联用对A549、PC-9细胞凋亡的影响,实时荧光定量PCR(quantitative real-time PCR,qRT-PCR)法检测NWXF和GEF单用及联用对A549、PC-9细胞EGFR、JNK、Bax mRNA表达的影响,蛋白印迹(Western blot,WB)法检测NWXF和GEF单用及联用对A549和PC-9细胞EGFR、p-EGFR、JNK、p-JNK、Bax蛋白表达的影响。结果共获取NWXF治疗NSCLC的77种活性成分、488个潜在靶点及49个关键靶点。GO富集分析结果显示,NWXF干预NSCLC可能与调控细胞增殖、凋亡过程及蛋白质磷酸化等生物学过程相关,KEGG富集分析结果显示,NWXF干预NSCLC可能与调控MAPK信号通路、PI3K-AKT信号通路、HIF-1.号通路及肿瘤中的microRNA等信号通路相关。NWXF中核心成分与关键靶点分子对接结果显示,91.9%的对接分值>5,表明核心成分与关键靶点有较好的结合能力。体外实验表明NWXF和GEF联用可协同抑制A549、PC-9细胞增殖,提高细胞凋亡率,抑制p-EGFR/EGFR、p-JNK/JNK蛋白表达水平和EGFR、JNK mRNA的表达水平,增加Bax mRNA和蛋白表达水平。综上,该研究利用网络药理学、分子对接和体外实验阐明NWXF联合GEF可协同治疗NSCLC,其作用机制与调控EGFR/JNK通路进而促进细胞凋亡相关。

关键词：温下方正丁醇部位吉非替尼非小细胞肺癌凋亡网络药理学分子对接机制

老年冠心病PCI术后心脏康复依从性影响因素分析

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现代科学仪器 2024年第4期41卷 149-152页

作者：毕彩琴韩美林合肥京东方医院康复科安徽合肥230013 合肥京东方医院护理部安徽合肥230013

目的:探讨老年冠心病经皮冠状动脉介入(PCI)术后心脏康复依从性影响因素。方法:根据PCI后依从性问卷将240例患者分为依从性良好组(1.5例)和依从性差组(1.5例),分析心脏康复依从性差的危险因素。结果:依从性差组文化初中及初中以下、年龄... 详细信息

目的:探讨老年冠心病经皮冠状动脉介入(PCI)术后心脏康复依从性影响因素。方法:根据PCI后依从性问卷将240例患者分为依从性良好组(1.5例)和依从性差组(1.5例),分析心脏康复依从性差的危险因素。结果:依从性差组文化初中及初中以下、年龄≥80岁、看病路程≥30km、家庭收入<2000元/月、照顾者为子女或保姆、独居、家庭支持度低占比高于依从性好组(P<0.05);回归分析证实以上因素为其心脏康复依从性差的危险因素(P<0.05)。结论:以上因素共同作用影响患者心脏康复依从性。

关键词：老年冠心病经皮冠状动脉介入心脏康复依从性

A Real-time Look-ahead Trajectory Planning Methodology for Multi Small Line Segments Path

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Chinese Journal of Mechanical Engineering 2023年第3期36卷 76-88页

作者： Sai Zhang Xinjun Liu {1.ngkai Yan Jie {1. Xiangdong han Department of Mechanical Engineering Tsinghua UniversityBeijing 100084China Robotphoenix Automation Technology Co. Ltd.Jinan 250100China

When a robot is required to machine a complex curved workpiece with high precision and speed,the tool path is typically dispersed into a series of points and transmitted to the *** conventional trajectory planning method requires frequent starts and stops at each dispersed point to complete the *** method not only reduces precision but also causes damage to the motors and robot.A real-time look-ahead algorithm is proposed in this paper to improve precision and minimize *** proposed algorithm includes a path-smoothing algorithm,a trajectory planning method,and a bidirectional scanning *** path-smoothing method inserts a quintic Bezier curve between small adjacent line segments to achieve G^(2)continuity at the *** trajectory planning method utilizes a quartic polynomial and a double-quartic polynomial that can achieve a constant velocity at the velocity *** bidirectional scanning module calculates the velocity at each trajectory planning segment point,simplifying calculation complexity and can be run in real *** feasibility of the proposed algorithm is verified through simulations and experiments,which can be run in real *** addition,high machining precision can be achieved by adjusting the relevant parameters.

关键词： Look-ahead bidirectional scanning Transition scheme Bezier curve G^(2)continuity

Anchorage performance of large-diameter FRP bolts and their application in large deformation roadway

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矿业科学技术学报:英文版 2023年第8期33卷 1037-1043页

作者： Jun han Zuoqing {1. {1.ng Liang Chen Cao Shuangwen Ma College of Mining Liaoning Technical UniversityFuxin 123000China ME EISUniversity of WollongongWollongongNSW 2526Australia

In underground coal mines, fibre reinforced polymer(FRP) bolt is ideal for mined rib reinforcements as it can prevent gas explosions caused by shearer frictional spark. With increasing mining depth, small diameter FRP bolts used in shallow underground mining cannot fulfil the rib support requirements. Under the engineering background of deep underground shortwall mining in Wudong coal mine, this paper systematically studies Φ27 mm FRP bolt support for large deformation coal rib. Specimens with a fan-shaped cross-section were used to enable the tensile testing of the bolt rod, the measured average tensile strength of the studied FRP bolt was(486.1.± 9.6) MPa with a maximum elongation of 5.7%±0.6%.The shear strength of the bolt was measured as approximately 258 MPa using a self-made double shear testing apparatus. Based on the equivalent radial stiffness principle, a laboratory short encapsulation pullout test(SEPT) method for rib bolting has been developed undertaken consideration of the mechanical properties of the coal seam. Results showed that the average peak anchorage forces of the Φ27 mm FRP bolt and Φ20 mm steel rebar bolt were 1.8.4 and 66.4 k N, respectively, which were agreed with the theoretical calculations and field measurements. Based on theoretical analysis of the loading states of the bolt under site conditions, bolting method of full-length resin grouting was adopted to offset the weaknesses of the FRP bolt. Numerical method was employed to compare the bolting effect using Φ27 mm FRP bolts and steel rebar bolts. Large diameter FRP bolting was determined as the optimum rib support scheme to increase the productivity of the coal mine and to enhance the ground control capability for+425 level mining roadways. This study provides the laboratory testing design and theoretical prediction of large diameter FRP bolts used for rib support in large deformation roadways.

关键词： FRP bolt Laboratory SEPT Tensile strength Double shear testing Mined rib support Large deformation roadway