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Chinese Guidelines for the Diagnosis and Management of Atrial Fibrillation

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Journal of Geriatric Cardiology 2024年第3期21卷 251-314页

作者： Chang-Sheng MA Shu-Lin WU Shao-Wen LIU Ya-Ling han Chinese Society of Cardiology Chinese Medical Association Heart Rhythm Committee of Chinese Society of biomedical Engineering Beijing Anzhen Hospital Capital Medical University Guandong Provincial People’s Hospital Shanghai First People’s Hospital General Hospital of Northern Theater Command 不详

Atrial fibrillation(AF)is the most common sustained cardiac arrhythmia,significantly impacting patients’quality of life and increasing the risk of death,stroke,heart failure,and *** the past two decades,there have been significant breakthroughs in AF risk prediction and screening,stroke prevention,rhythm control,catheter ablation,and integrated *** this period,the scale,quality,and experience of AF management in China have greatly improved,providing a solid foundation for the development of guidelines for the diagnosis and management of *** further promote standardized AF management,and apply new technologies and concepts to clinical practice in a timely and comprehensive manner,the Chinese Society of Cardiology of the Chinese Medical Association and the Heart Rhythm Committee of the Chinese Society of biomedical Engineering have jointly developed the Chinese Guidelines for the Diagnosis and Management of Atrial *** guidelines have comprehensively elaborated on various aspects of AF management and proposed the CHA2DS2-VASc-60 stroke risk score based on the characteristics of AF in the Asian *** guidelines have also reevaluated the clinical application of AF screening,emphasized the significance of early rhythm control,and highlighted the central role of catheter ablation in rhythm control.

关键词： prevention sustained diagnosis

融合抽象语义表示和依存语法的方面级情感分析

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数据分析与知识发现 2024年第1期8卷 55-68页

作者：李雪莲王碧李立鑫韩迪轩南京邮电大学外国语学院南京210023 江西理工大学信息工程学院赣州341000 东南大学计算机科学与工程学院南京210096 佐治亚理工学院电子计算机工程学院亚特兰大30318

【目的】充分融合自然语言句子的深层语义表示和表层语法结构,实现语义和语法的互补。【方法】提出基于规则串联的抽象语义表示和依存语法集成策略,并进行方面级情感分析。该策略利用回答集编程语言(ASP)将抽象语义表示、依存语法、词... 详细信息

【目的】充分融合自然语言句子的深层语义表示和表层语法结构,实现语义和语法的互补。【方法】提出基于规则串联的抽象语义表示和依存语法集成策略,并进行方面级情感分析。该策略利用回答集编程语言(ASP)将抽象语义表示、依存语法、词性分别表示为ASP事实,并基于抽象语义规则,通过规则体扩展的方式集成依存语法和词性,即将一个句子中的多种语言特征依次在规则体中进行串联来使用。该策略实现了两种方法:集成语义、语法和词性信息的AMR-DEP-POS-C方法;忽略词性信息的AMR-DEP-C方法。【结果】在8个公开评论数据集上的实验表明,AMR-DEP-POS-C方法能够实现语义和语法间的互补,比语义规则方法、语法规则方法以及基于深度学习的方法具有更好性能。【局限】该方法依赖于现有抽象语义表示和依存语法分析工具的准确性。【结论】AMR-DEP-POS-C方法具有可解释性,不需要大规模数据集,能够有效融合不同的语言特征,可为方面级情感分析任务带来新的研究视角和工具。

关键词：抽象语义表示依存语法规则方面级情感分析

A giant Ce-containing poly(tungstobismuthate): Synthesis, structure and catalytic performance for the decontamination of a sulfur mustard simulant

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Chinese Chemical Letters 2024年第10期35卷 491-494页

作者： Chen Lian Si-han Zhao Hai-Lou Li Xinhua Cao MOE Key Laboratory of Cluster Science School of Chemistry and Chemical Engineering Beijing Institute of Technology College of Chemistry and Chemical Engineering Xinyang Normal University

A novel Ce-containing poly（tungstobismuthate） Cs1.Na8H20[Ce3（H2O）1.W8bi4O28(B-α-bi W9O33)4]2·64H2O（1. has been synthesized by a facile one-pot self-assembly reaction strategy. Its structural characterization is realized by virtue of single-crystal X-ray diffraction, infrared spectroscopy, powder X-ray diffraction and thermogravimetric analysis. The polyoxoanion of 1.is an octameric architecture consisting of two tetrameric entities [Ce3（H2O）1.W8bi4O28(B-α-bi W9O33)4]23-linked by two Ce–O–W bonds, and adjacent polyoxoanions are further combined together by means of Ce3+linkers, resulting in an infinite 1. chain architecture. Compound 1.is the currently largest tungstobismuthate, and also represents the first example of lanthanide-encapsulated tungstobismuthate exhibiting an extended structure. Furthermore,compound 1.as a heterogeneous catalyst, exhibits high activity for the oxidative decontamination of a sulfur mustard simulant, 2-chloroethyl ethyl sulfide（CEES） into 2-chloroethyl ethyl sulfoxide（CEESO）.

关键词： Cluster Lanthanide Oxidation Polyoxometalates Tungstobismuthate

Macroscopic polarization enhancement boosting piezo-photocatalytic performance via Nb-doping on B-site of {1._(4)Ti_(3)O_(1.)nanosheets

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Journal of Advanced Ceramics 2024年第4期13卷 437-446页

作者： Hongjian Yu Xindong Wei Min Wang Yan Zhang Zheng Wu Fan Guo Jie han School of Chemistry and Chemical Engineering Yangzhou UniversityYangzhou 225002China Engineering Research Center of Ministry of Education for Geological Carbon Storage and Low Carbon Utilization of Resources Beijing Key Laboratory of Materials Utilization of Nonmetallic Minerals and Solid WastesNational Laboratory of Mineral MaterialsSchool of Material Sciences and TechnologyChina University of Geosciences(Beijing)Beijing 100083China School of Environmental and Chemical Engineering Xi’an Key Laboratory of Textile Chemical Engineering AuxiliariesXi'an Polytechnic UniversityXi'an 710048China

The development of a high-performance ferroelectric piezo-photocatalyst is an efficient strategy for advancing sustainability within the environmental and energy ***,a major challenge lies in the creation of a strong polarized electric field that can effectively hinder charge recombination,both within the bulk and on the surface of ***,we synthesize a series of Nb-doped bi_(4)Ti_(3)O_(1.)nanosheets via a facile one-pot hydrothermal method to achieve synergistically enhanced piezo-photocatalytic performance in CO_(2)reduction and pollutant *** optimized doped bi_(4)Ti_(3)O_(1.)demonstrates remarkable efficiency in the conversion of CO_(2)into CO,with a high production rate of 72.7μmol∙g−1.h−1.without using co-catalysts or any sacrificial agent,surpassing the performance of unmodified bi_(4)Ti_(3)O_(1.)by up to 4.69 ***,our catalyst demonstrates ultra-fast piezo-photocatalytic degradation of organic pollutant Rhodamine B(RhB)at low concentrations and exceptional piezo-photocatalytic activity at high concentrations,outperforming most previously reported state-of-the-art *** systematic corroboration of catalyst characterization and experimental analysis reveals that the synergistic effect arises from the amplified macroscopic polarization induced by lattice distortion caused by the larger Nb ions,thereby improving piezo-photocatalytic *** research thus offers valuable insights into the direct design and fabrication of versatile catalytic systems,with applications spanning CO_(2)valorization and beyond.

关键词： CO_(2)reduction dye degradation piezo-photocatalysis Nb-doped bi_(4)Ti_(3)O_(1.) macroscopic polarization regulation

Poly(3-hexylthio) thiophene Field-effect Transistor Device Performance: Impact of the Content of Hexylthio Side Chain on Backbone

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Chinese Journal of Polymer Science 2024年第1期42卷 14-23,I0005页

作者： Hao-Yu Liu Lian-He han Ling-Wei Kong Li-Ping Zhu Xiao-Lan Qiao Mei-Fang Zhu State Key Laboratory for Modification of Chemical Fibers and Polymer Materials College of Materials Science and EngineeringDonghua UniversityShanghai 201620China School of Electronic Information and Electrical Engineering Shanghai Jiao Tong UniversityShanghai 200240China

Regioregular poly(3-hexylthio)thiopene(P3HTT) has emerged tremendous potential in organic electronic applications due to the strong noncovalent interactions from the sulfur atom linked to thiophene. However, P3HTT generally exhibits low charge mobility mostly due to poor solution processability attributed to dense arrangement of hexylthio side chain in polymer, which led to strong noncovalent interactions among sulfur atoms. To balance the nonvalent interaction and aggregation for P3HTT, herein, we systematically study the effect of hexylthio side chain content in polymer backbone on the structure and properties. A series of regioregular P3HTT-based homopolymers(P3HTT, P3HTT-50,P3HTT-33 and P3HTT-25) were prepared via Kumada catalyst transfer polycondensation method from a set of mono-, bi-, ter-and quarterthiophenes containing different contents of hexylthio side chain. The DFT calculation shows the planarity of polymers backbone could be improved through reducing the density of hexylthio side chain in polymer mainchain. And significant changes in their crystallinity, aggregation and optical properties were observed with the content of hexylthio side chain reducing. The P3HTT-33 displayed the highest field-effect transistor hole mobility of 2.83×1.^(-2) cm^(2)·V^(-1.·s^(-1. resulting from a balance between the crystallinity and planarity. This study demonstrates modulating the content of hexylthio side chain in P3HTT is an effective strategy to optimize the opto-electronic properties of polymer obtaining excellent semiconductor device performance.

关键词： Conjugated polymer Polythiophene Noncovalent interaction Molecular aggregation Organic field-effect transistor

A self-powered solar-blind UV-enhanced {1._(2)Se_(3)/a-Ga_(2)O_(3)/p-Si heterojunction photodetector for full spectral photoresponse and imaging

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Nano Research 2024年第4期17卷 2960-2970页

作者： Yajie han Shujie Jiao Jiangcheng Jing Lei Chen Ping Rong Shuai Ren Dongbo Wang Shiyong Gao Jinzhong Wang School of Materials Science and Engineering Harbin Institute of TechnologyHarbin 150001China

Self-powered full-spectrum photodetectors(PDs)offer numerous advantages,such as broad application fields,high precision,efficiency,and multi-functionality,which represent a highly promising and potentially valuable class of detectors for future ***,insensitive response to solar-blind ultraviolet(UV)and complex and expensive preparation processes greatly limit their performance and practical *** this study,a self-powered full-spectrum bi_(2)Se_(3)/a-Ga_(2)O_(3)/p-Si heterojunction PD with high sensitivity for solar-blind UV band prepared by a simple and low-cost two-step synthesis method is *** results reveal that the developed PD has an excellent performance,such as high sensitivity from 200 to 850 nm,and a responsivity of 1.38 mA/W as well as a detectivity of 3.22×1.^(1.) Jones under 254 nm light at zero ***,the unencapsulated device displays exceptional stability and imaging *** is expected that bi_(2)Se_(3)/a-Ga_(2)O_(3)/p-Si heterojunction PD with a simple and low-cost synthesis method has great potential for self-powered full-spectrum photodetectors.

关键词： bi_(2)Se_(3)/a-Ga_(2)O_(3)/p-Si self-powered photodetector full spectral photoresponse imaging

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不同衣藻光合作用响应汞胁迫的比较研究

水生生物学报 2024年第6期48卷 1040-1050页

作者：夏亦雪艾晓寒朱飞霞毕永红中国科学院水生生物研究所淡水生态与生物技术国家重点试验室武汉430072 中国科学院大学北京100049 大连海洋大学水产与生命学院大连116023

为筛选耐受汞胁迫的衣藻(Chlamydomonas reinhardtii)藻株,研究不同衣藻光合作用过程响应汞胁迫的差异,比较了不同汞浓度下1.株衣藻的生长、叶绿素a含量及叶绿素荧光活性。结果表明,随着汞离子浓度升高,叶绿素a含量显著下降且生长受抑制... 详细信息

为筛选耐受汞胁迫的衣藻(Chlamydomonas reinhardtii)藻株,研究不同衣藻光合作用过程响应汞胁迫的差异,比较了不同汞浓度下1.株衣藻的生长、叶绿素a含量及叶绿素荧光活性。结果表明,随着汞离子浓度升高,叶绿素a含量显著下降且生长受抑制,叶绿素荧光活性参数W_(k)、V_(j)和M_(o)快速增加,ψ_(o)和φEo快速下降,表明光合系统Ⅱ(PSⅡ)反应中心的供体侧和受体侧的电子传递受阻,光合活性被抑制。在1.株衣藻中,衣藻FACHB-889(EC_(50)为0.762 mg/L)对汞耐受能力最弱,衣藻FACHB-221.对汞耐受能力最强(EC_(50)为2.848 mg/L)。与对照相比,在低浓度汞(1.光合系统Ⅱ(PSⅡ)活性无显著差异。在高浓度汞(>1.0 mg/L)胁迫下,衣藻FACHB-889光合活性受抑制,单位面积活性反应中心数量(RC/CS_(o))显著下降(P1.单位活性反应中心吸收的能量(ABS/RC)、用于还原Q_(A)的能量(TR_(o)/RC)及用于电子传递的能量(ET_(o)/RC)均显著升高,细胞通过有活性的单位反应中心光合能力的增强,有效转化吸收的能量,消除部分反应中心失活的负面影响。研究表明,光合活性及其能量分配的差异是衣藻对汞敏感/耐受的重要原因。

关键词：汞光系统Ⅱ 毒性效应衣藻

姜黄提取物的抑菌活性及对细菌胞膜作用的研究

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药学学报 2024年第8期59卷 2265-2272页

作者：罕璐周超毕秀芳黄梅桂郝刚西南民族大学食品科学与技术学院四川成都610041

本研究通过测定最小抑菌浓度(minimum inhibitory concentration, MIC)分析姜黄提取物的抑菌谱,并通过检测姜黄提取物对抑制效果最佳的受试菌(枯草芽孢杆菌)细胞膜的通透性及完整性、能量代谢及菌体形态的影响,阐述姜黄提取物的膜作用... 详细信息

本研究通过测定最小抑菌浓度(minimum inhibitory concentration, MIC)分析姜黄提取物的抑菌谱,并通过检测姜黄提取物对抑制效果最佳的受试菌(枯草芽孢杆菌)细胞膜的通透性及完整性、能量代谢及菌体形态的影响,阐述姜黄提取物的膜作用抑菌机制。结果表明,姜黄提取物具有广谱抑菌活性,对革兰阳性菌、革兰阴性菌及真菌均有一定抑制作用,对枯草芽孢杆菌的抑制活性最强, MIC为0.5 mg·mL^(-1.。姜黄提取物可扰乱脂质体膜释放钙黄绿素,能增加细菌胞膜通透性引起胞内K^(+)、Ca^(2+)和细胞壁间蛋白的泄漏,以及破坏细胞膜的完整性,使胞内蛋白、多糖外漏。扫描电镜观察证实经姜黄提取物处理的细菌形态严重变形,在此过程中还影响细胞能量代谢,使细菌胞内ATP含量和ATP酶活力显著降低。因此姜黄提取物具有的抑菌活性与其破坏细菌膜结构的作用密切相关。

关键词：姜黄提取物枯草芽孢杆菌抑菌活性膜作用机制

利用斑马鱼模型和代谢组学技术研究丹红注射液促进血管生成作用及潜在代谢机制

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中草药 2024年第16期55卷 5551-5558页

作者：王芳毕成浩毕文杰李梦娇王松松韩利文李遇伯天津中医药大学中药学院天津301617 山东第一医科大学(山东省医学科学院)药学院山东济南250117

目的基于斑马鱼模型研究丹红注射液促进血管生成作用,并利用代谢组学和qRT-PCR技术探索其代谢机制。方法利用血管特异标记绿色荧光蛋白的转基因品系Tg(fli1.EGFP)斑马鱼作为模式动物,观察丹红注射液对斑马鱼节间血管的促进作用。利用基... 详细信息

目的基于斑马鱼模型研究丹红注射液促进血管生成作用,并利用代谢组学和qRT-PCR技术探索其代谢机制。方法利用血管特异标记绿色荧光蛋白的转基因品系Tg(fli1.EGFP)斑马鱼作为模式动物,观察丹红注射液对斑马鱼节间血管的促进作用。利用基于超高效液相色谱-四极杆飞行时间质谱联用技术(ultra performance liquid chromatography quadrupole time of flightmass spectrometry,UPLC-Q-TOF-MS)的非靶向代谢组学检测斑马鱼在血管生成表型变化过程中的内源性差异代谢物,进一步利用qRT-PCR技术探索与丹红注射液促进血管生成作用相关的潜在代谢机制。结果丹红注射液能够呈剂量相关性地逆转血管内皮细胞生长因子受体抑制剂PTK787对斑马鱼节间血管的抑制作用(P1.。与模型组比较,丹红注射液组有7个内源性代谢物水平发生了显著变化,主要与戊糖磷酸途径、精氨酸和鸟氨酸代谢途径相关。qRT-PCR结果显示,丹红注射液显著逆转了斑马鱼体内与戊糖磷酸通路关键酶6-磷酸葡萄糖脱氢酶(glucose-6-phosphate dehydrogenase,g6pd)、转醛缩酶(transaldolase 1.taldo1.、转酮醇酶(transketolase a,tkta)、核糖-5-磷酸异构酶A(ribose 5-phosphate isomerase A,rpia)和5-磷酸核酮糖3-差向异构酶(ribulose-5-phosphate-3-epimerase,rpe)基因的表达水平(P1.。结论利用斑马鱼模型验证了丹红注射液的显著血管生成作用,代谢组学和qRT-PCR研究结果表明其血管生成主要与磷酸戊糖途径有关。

关键词：丹红注射液血管生成斑马鱼代谢组学磷酸戊糖途径