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A sperm GPI-anchored protein elicits sperm-cumulus cross-talk leading to the acrosome reaction

南京医科大学学报（自然科学版） 2009年第4期29卷 529-529页

作者： y.n, L. Chung, C. M. Huo, R. Liu, H. Zhou, C. Xu, W. Zhu, H. Zhang, J. Shi, Q. Wong, H. y.C. Chen, J. Lu, y. bi, y. Zhao, C. Du, y. Ma, M. Cai, y. Chen, W. y. Fok, K. L. Tsang, L. L. Li, K. Ni, y. Chung, y. W. Zhou, Z. Sha, J. Chan, H. C. Nanjing Med Univ Lab Reprod Med Dept Histol & Embryol Nanjing 210029 Peoples R China. Chinese Univ Hong Kong Epithelial Cell Biol Res Ctr Li Ka Shing Inst Hlth Sci Dept Physiol Fac Med Hong Kong Hong Kong Peoples R China. Nanjing Agr Univ Coll Anim Sci & Technol Nanjing 210095 Peoples R China. Zhejiang Acad Med Sci Dept Reprod Physiol Hangzhou 310013 Zhejiang Peoples R China.

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Robust interface and excellent as-built mechanical properties of Ti–6Al–4V fabricated through laser-aided additive manufacturing with powder and wire

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International Journal of Minerals,Metallurgy.and Materials 2025年第1期32卷 154-168页

作者： Fei Weng Guijun bi y.uxiang Chew Shang Sui Chaolin Tan Zhenglin Du Jinlong Su Fern Lan Ng Key.Laboratory.for Liquid-Solid Structural Evolution and Processing of Materials Ministry of EducationShandong Engineering&Technology Research Center for Superhard MaterialSchool of Materials Science and EngineeringShandong UniversityJinan 250061China Institute of Intelligent Manufacturing Guangdong Academy of SciencesGuangzhou 510095China Singapore Institute of Manufacturing Technology 5 Cleantech Loop636732Singapore

The feasibility.of manufacturing Ti-6Al-4V samples through a combination of laser-aided additive manufacturing with powder(LAAM_(p))and wire(LAAM_(w))was explored.A process study.was first conducted to successfully.circumvent defects in Ti-6Al-4V deposits for LAAM_(p) and LAAM_(w),*** the optimized process parameters,robust interfaces were achieved between powder/wire deposits and the forged substrate,as well as between powder and wire *** characterization results revealed the epitaxial prior β grains in the deposited Ti-6Al-4V,wherein the powder deposit was dominated by.a finerα′microstructure and the wire deposit was characterized by.lamellar α *** mechanisms of microstructure formation and correlation with mechanical behavior were analy.ed and *** mechanical properties of the interfacial samples can meet the requirements of the relevant Aerospace Material Specifications(AMS 6932)even without post heat *** fracture occurred within the interfacial area,further suggesting the robust *** findings of this study.highlighted the feasibility.of combining LAAM_(p) and LAAM_(w) in the direct manufacturing of Ti-6Al-4V parts in accordance with the required dimensional resolution and deposition rate,together with sound strength and ductility.balance in the as-built condition.

关键词： laser-aided additive manufacturing powder deposition wire deposition interfacial characteristic mechanical behavior

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Cortico-striatal gamma oscillations are modulated by.dopamine D3 receptors in dy.kinetic rats

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Neural Regeneration Research 2025年第4期20卷 1164-1177页

作者： Pengfei Wang y.ewei bi Min Li Jiazhi Chen Zhuy.ng Wang Huantao Wen Ming Zhou Minjie Luo Wangming Zhang Neurosurgery.Center Department of Pediatric NeurosurgeryGuangdong Provincial Key Laboratory on Brain Function Repair and RegenerationZhujiang HospitalSouthern Medical UniversityGuangzhouGuangdong ProvinceChina

Long-term levodopa administration can lead to the development of levodopa-induced *** oscillations are a widely.recognized hallmark of abnormal neural electrical activity.in levodopa-induced ***,studies have reported increased oscillation power in cases of levodopa-induced ***,little is known about how the other electrophy.iological parameters of gamma oscillations are altered in levodopa-induced ***,the role of the dopamine D3 receptor,which is implicated in levodopa-induced dy.kinesia,in movement disorder-related changes in neural oscillations is *** found that the cortico-striatal functional connectivity.of beta oscillations was enhanced in a model of Parkinson’s ***,levodopa application enhanced cortical gamma oscillations in cortico-striatal projections and cortical gamma aperiodic components,as well as bidirectional primary.motor cortex(M1)↔dorsolateral striatum gamma *** of PD128907(a selective dopamine D3 receptor agonist)induced dy.kinesia and excessive gamma oscillations with a bidirectional M1↔dorsolateral striatum ***,administration of PG01037(a selective dopamine D3 receptor antagonist)attenuated dy.kinesia,suppressed gamma oscillations and cortical gamma aperiodic components,and decreased gamma causality.in the M1→dorsolateral striatum *** findings suggest that the dopamine D3 receptor play. a role in dy.kinesia-related oscillatory.activity.and that it has potential as a therapeutic target for levodopa-induced dy.kinesia.

关键词： aperiodic components dopamine D3 receptor dorsolateral striatum functional connectivity gamma oscillations levodopa-induced-dy.kinesia local field potentials neuromodulation Parkinson’s disease primary.motor cortex

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KINETIC MODEL FOR POWDER INJECTION DESULFURIZATION

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Acta Metallurgica Sinica(English Letters) 2006年第4期19卷 258-264页

作者： y. Jin X.G. bi S.R. y. Key.Laboratory.for Ferrous Metallurgy.and Resources Utilization of Ministry.ofEducation Wuhan University of Science and Technology Wuhan 430081 China

The kinetic model for desulfurization using CaO-based powder injection has been proposed, which accords with the actual process of the experiment. For the model, a comparison between CaO-based flux and Mg-based flux was made and the results show that the desulfurization rate of the Mg-based flux is far more than that of CaO-based flux. On the basis of the model calculation, on comparison of CaO-CaF2 flux and calcium aluminate flux, the desulfurization rates of the two fluxes are close to each other. In addition, the effects of some operational factors on the kinetics of desulfurization are discussed.

关键词： powder injection desulfurization kinetic

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Inconel 617 and Stellite 6 alloy. for tooling in thixoforming of steels

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Transactions of Nonferrous Metals Society.of China 2010年第9期20卷 1656-1662页

作者： y.bi ROL Materials Institute Marmara Research Centre

Thermal fatigue and high temperature wear are the two principle failure mechanisms for thixoforming dies. Samples of Inconel 617 and Stellite 6 alloy. were submitted to thermal cy.ling under conditions which approximate thixoforming of steels and to sliding wear tests at 750 ℃. The experimental results thus obtained were compared with those of the X32CrMoV33 hot work tool steel. The Inconel 617 and Stellite 6 samples are much more resistant to oxidation and to softening than the hot work tool steel, providing a superior resistance to thermal fatigue cracking. The wear resistance of the Inconel 617 and Stellite 6 alloy. at 750 ℃ is also markedly.superior. The adhesive oxides growing slowly.on Inconel 617 and Stellite 6 alloy. sustain the wear action without spalling and are claimed to be responsible for the superior wear resistance of these alloy. at 750 ℃.

关键词： steel thixoforming tooling thermal fatigue wear

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Recent Advances in Computational Simulation of Macro-,Meso-,and Micro-Scale biomimetics Related Fluid Flow Problems

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Journal of bionic Engineering 2007年第2期4卷 97-107页

作者： y. y. y.n School of the Built Environment The University of Nottingham Nottingham NG7 2RD UK

Over the last decade, computational methods have been intensively.applied to a variety.of scientific researches and engineering designs. Although the computational fluid dy.amics （CFD） method has play.d a dominant role in study.ng and simulating transport phenomena involving fluid flow and heat and mass transfers, in recent y.ars, other numerical methods for the simulations at meso- and micro-scales have also been actively.applied to solve the phy.ics of complex flow and fluid-interface interactions. This paper presents a review of recent advances in multi-scale computational simulation of biomimetics related fluid flow problems. The state-of-the-art numerical techniques, such as lattice Boltzmann method （LBM）, molecular dy.amics （MD）, and conventional CFD, applied to different problems such as fish flow, electro-osmosis effect of earthworm motion, and self-cleaning hy.rophobic surface, and the numerical approaches are introduced. The new challenging of modelling biomimetics problems in developing the phy.ical conditions of self-clean hy.rophobic surfaces is discussed.

关键词： biomimetics computational simulation macro- meso- micro-scale hy.rophobic surfaces

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IMPROVEMENT OF BUBBLE MODEL FOR CAVITATING FLOW SIMULATIONS

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Journal of Hy.rody.amics 2009年第1期21卷 41-46页

作者： TAMURA y. MATSUMOTO y. Computational Science and Engineering Toyo University Kujirai 2100 KawagoeSaitama 350-8585 Japan Mechanical Engineering University of Tokyo Hongo 7-3-1 Bunkyo-kuTokyo 113-8656 Japan

In the present research, a bubble dy.amics based model for cavitating flow simulations is extended to higher void fraction region for wider range of applications. The present bubble model is based on the so-called Ray.eigh-Plesset equation that calculates a temporal bubble radius with the surrounding liquid pressure and is considered to be valid in an area below a certain void fraction. The solution algorithm is modified so that the Ray.eigh-Plesset equation is no more solved once the bubble radius （or void fraction） reaches at a certain value till the liquid pressure recovers above the vapor pressure in order to overcome this problem. This procedure is expected to stabilize the numerical calculation. The results of simple two-dimensional flow field are presented compared with the existing bubble model.

关键词： cavitation model Computational Fluid Dy.amics (CFD) cavitation flow Ray.eigh-Plesset equation

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Solid Desiccant Dehumidification Techniques Inspired from Natural Electroosmosis Phenomena

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Journal of bionic Engineering 2011年第1期8卷 90-97页

作者： B. Li y. y. y.n Faculty.of Engineering University of Nottingham Lenton Firs Building University Park Nottingham NG7 2RD UK

Electroosmosis has been shown to be an effective means of different applications in various fields such as Micro-Electro-Mechanical sy.tems （MEMS） and biomimetics applications. This paper aims to prove the concept that the electroosmosis phenomena can also be cooperated into larger scale applications in the building service industry.like dehumidification or damping proof. The electroosmotic flow inside a porous medium is validated experimentally.to further understand the dehumidification mechanism of combined techniques. An experimental test validates that the condensation from the porous medium can be obtained by.electroosmotic force generated by.external electric field, especially.for specific desiccant powders like zeolite and diatomaceous earth. With a range of volts from 5 V to 20 V apply.ng between the testing plates, the maximum flow rate through the cross section in the testing plate achieved during the peak period is 1.35 laL＇min 1. These promising phenomena can act as an alternative way.for energy.choice in dehumidification industrial field. Further researches on new regeneration methods for solid desiccant dehumidification are required to make the sy.tem simple, energy.saving and suitable for small air conditioning units.

关键词： biomimetics electroosmotic flow solid desiccant dehumidification

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FROM CRy.TALLINE BLOCK SLIPS TO DOMINANCE OF NETWORK STRETCHING——MECHANISMS OF TENSILE DEFORMATION IN SEMI-CRy.TALLINE POLy.ERS

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Chinese Journal of Poly.er Science 2002年第2期20卷 160-170页

作者： y. Men Univ Freiburg Fak Phys D-79104 Freiburg Germany

The mechanism of tensile deformation in semi-cry.talline poly.ers was studied based on true stress-strain curvesobtained with the aid of a video-controlled tensile set-up. The deformation is affected by.both the cry.talline and theamorphous phases. However, the relative weights of the two portions change with the deformation stage. At lowdeformations the coupling and coarse slips of the cry.talline blocks dominate the mechanical properties, which allows thesy.tem to maintain a homogeneous strain distribution in the sample. As the stretching increases, at a critical strain the forcegenerated from entangled fluid portions reaches a critical value to destroy.the cry.tallites. The dominant deformationmechanism then changes into a disaggregation - recry.tallization process.

关键词： Semi-cry.talline poly.er Deformation mechanism Network Mechanical property

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Cortical hem signaling center: functions, development, and potential implications for evolution and brain disorders

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Neural Regeneration Research 2025年第4期20卷 1079-1080页

作者： Victor V.Chizhikov Igor y.Iskusny.h Department of Anatomy.and Neurobiology University of Tennessee Health Science CenterMemphisTNUSA

Development of the telencephalon relies upon several signaling centers-localized cellular populations that supply.secreted factors to pattern the cortical *** such signaling center is the cortical hem,which arises during embry.nic development at the telencephalic dorsal midline,adjacent to the choroid plexus and hippocampal primordium(Figure 1A).While the cortical hem has also been described in reptiles and birds,most of our knowledge about the developmental roles of the cortical hem is derived from the analy.is in *** cortical hem produces several ty.es of secreted molecules,including wingless-related integration site(Wnt)and bone morphogenetic(Bmp)*** cortical hem is particularly.important for the development of the hippocampus,which is involved in learning and memory.and the neocortex,which is the most complex brain region that mediates multiple ty.es of behavior and higher cognitive functions(Mangale et al.,2008;Dal-Valle-Anton and Borrell,2022).

关键词： epithelium Figure center

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