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Hepatobiliary & Pancreatic Diseases International 2016年第5期15卷 546-552页

作者： Omar J Shah Sadaf A Bangri Manmohan Singh Reyaz A Lattoo Mohammad Y bhat Feroze A Khan Department of Surgical Gastroenterology Sher-i-Kashmir Institute of Medical Sciences

BACKGROUND: Fast track strategy in the management of patients undergoing intra-abdominal surgery of various types has emerged as a landmark approach to reduce surgical stress and accelerate recovery. This study was to evaluate the effect of fast track strategy on patients subjected to pancreaticoduo-denectomy (PD) from an individual unit during transit from low to a high volume center. METHODS: A total of 142 PD patients who had been subjected to fast track strategy between June 2008 and September 2012 were compared with 46 patients who had received convention-al surgery between January 2006 and May 2008. Comparative analysis was made of postoperative complications, postopera-tive recovery, length of hospital stay and patient readmission requirement. RESULTS: The patients subjected to fast track strategy had a faster recovery and a shorter hospital stay than those who were treated conventionally (7.8 vs 12.1 days). The intraoperative events like operative blood loss (417.9±83.8 vs 997.4 ±151.8 mL, P CONCLUSIONS: This preliminary analysis suggests that the fast track approach might be beneifcial to the well-being of the patients after PD, for it accelerates the immediate clinical recovery of patients and signiifcantly shortens their length of hospital stay.

关键词： fast track recovery pancreaticoduodenectomy

Connective tissue growth factor expression hints at aggressive nature of colorectal cancer

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World Journal of Gastroenterology 2022年第5期28卷 547-569页

作者： Ishrat Parveiz bhat Tahseen Bilal Rather Irfan Maqbool Gowhar Rashid Kulsum Akhtar Gulzar A bhat Fazl Q Parray Besina Syed Ishrat Younas Khan Mohsin Kazi Muhammad D Hussain Mudassar Syed Department of Clinical Biochemistry Sher-I-Kashmir Institute of Medical SciencesSrinagar 190011Jammu and KashmirIndia Department of General Surgery Sher-I-Kashmir Institute of Medical SciencesSrinagar 190011Jammu and KashmirIndia Department of Pathology Sher-I-Kashmir Institute of Medical SciencesSrinagar 190011Jammu and KashmirIndia Department of Pharmaceutics College of PharmacyKing Saud UniversityPO Box 2457Riyadh 11451Saudi Arabia Department of Pharmaceutical and Biomedical Sciences California Health Sciences UniversityCaliforniaCA 93612United States

BACKGROUND Connective tissue growth factor(CTGF)is a mediator of transforming growth factor-beta signaling and plays a key role in connective tissue remodeling,inflammatory processes and fibrosis in various illnesses including *** To investigate the role of CTGF in colorectal cancer(CRC)progression and to compare the CTGF expression with different clinicopathological *** Real-time polymerase chain reaction,immunohistochemistry and Western blotting was performed to evaluate the CTGF expression and the results were statistically analyzed against the clinicopathological variables of patient data using STATA software version *** CTGF expression levels in tumor specimens were significantly higher than their paired normal *** higher protein expression levels showed a significant association with smoking,staging,tumor grade,invasion depth,necrosis of tumor tissue,and both lymphovascular and perineural *** per the cox regression model and classification tree analysis,tumor-nodemetastasis stage and perineural invasion were important predictors for CTGF expression and prognosis of CRC *** analysis indicated that CTGF overexpression was associated with poorer overall and disease-free *** Expression of CTGF was increased in CRC and was linked with poor overall and disease-free survival of CRC *** findings support prior observations and thus CTGF may be a possible prognostic marker in CRC.

关键词： Connective tissue growth factor Quantitative real time polymerase chain reaction Immunohistochemistry Western blotting Colorectal cancer

Identification of QTLs for Yield and Associated Traits in F_(2) Population of Rice

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Phyton-International Journal of Experimental Botany 2022年第11期91卷 2439-2459页

作者： Rohini bhat Anil Kumar Singh Muntazir Mushtaq Romesh Kumar Salgotra Manmohan Sharma Basharat Ahmad bhat Umer Basu Ibrahim Al-Ashkar Mohammad Anwar Hossain Akihiro Ueda Ayman El Sabagh ICAR-Directorate of Onion and Garlic RajgurunagarPuneMaharashtra410505India School of Biotechnology Sher-e-Kashmir University of Agricultural Sciences and Technology of JammuChatha180009India ICAR-National Bureau of Plant Genetic Resources Pusa CampusNew Delhi110012India Department of Bio-Resources University of KashmirJammu and Kashmir190006India Division of Plant Pathology Sher-e-Kashmir University of Agricultural Sciences and Technology of JammuChatha180009India Department of Plant Production College of Food and AgricultureKing Saud UniversityRiyadh11451Saudi Arabia Department of Genetics and Plant Breeding Bangladesh Agricultural UniversityMymensingh2202Bangladesh Graduate School of Integrated Sciences for Life Hiroshima UniversityHigashi-Hiroshima739-8528Japan Department of Agronomy Faculty of AgricultureKafrelsheikh UniversityKafrelsheikh33516Egypt

Identification of quantitative trait loci(QTLs)controlling yield and yield-related traits in rice was performed in the F_(2) mapping population derived from parental rice genotypes DHMAS and K343.A total of 30 QTLs governing nine different traits were identified using the composite interval mapping(CIM)*** QTLs were mapped for number of tillers per plant on chromosomes 1(2 QTLs),2 and 3;three QTLs for panicle number per plant on chromosomes 1(2 QTLs)and 3;four QTLs for plant height on chromosomes 2,4,5 and 6;one QTL for spikelet density on chromosome 5;four QTLs for spikelet fertility percentage(SFP)on chromosomes 2,3 and 5(2 QTLs);two QTLs for grain length on chromosomes 1 and 8;three QTLs for grain width on chromosomes1,3 and 8;three QTLs for 1000-grain weight(TGW)on chromosomes 1,4 and 8 and six QTLs for yield per plant(YPP)on chromosomes 2(3 QTLs),4,6 and *** of the QTLs were detected on chromosome 2,so further studies on chromosome 2 could help unlock some new chapters of QTL for this cross of rice *** QTLs elucidating high phenotypic variance can be used for marker-assisted selection(MAS)***,the exploitation of information regarding molecular markers tightly linked to QTLs governing these traits will facilitate future crop improvement strategies in rice.

关键词： Rice QTL mapping linkage map SSR markers composite interval mapping marker-assisted selection

Guinea pigs as an animal model for sciatic nerve injury

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Neural Regeneration Research 2017年第3期12卷 452-457页

作者： Malik Abu Rafee Amarpal Prakash Kinjavdekar Hari Prasad Aithal Sajad Ahmad Wani Irfan Ahmad bhat Division of Surgery Indian Veterinary Research InstituteIzatnagarBareillyUPIndia Division of Veterinary Biotechnology Indian Veterinary Research InstituteIzatnagarBareillyUPIndia Division of Veterinary Physiology Indian Veterinary Research InstituteIzatnagarBareillyUPIndia

The overwhelming use of rat models in nerve regeneration studies is likely to induce skewness in treatment *** address the problem,this study was conducted in 8 adult guinea pigs of either sex to investigate the suitability of guinea pig as an alternative model for nerve regeneration studies.A crush injury was inflicted to the sciatic nerve of the left limb,which led to significant decrease in the pain perception and neurorecovery up to the 4th *** of foot print and shortening of toe spread were observed in the paw after nerve injury.A 3.49 ± 0.35 fold increase in expression of neuropilin 1（NRP1） gene and 2.09 ± 0.51 fold increase in neuropilin 2（NRP2） gene were recorded 1 week after nerve injury as compared to the normal *** of gastrocnemius muscle weight and volume of the experimental limb to control limb showed more than 50% decrease on the 30 th ***,vacuolated appearance of the nerve was observed with presence of degenerated myelin debris in digestion *** muscle also showed degenerative *** electron microscopy revealed loose and rough arrangement of connective tissue fibrils and presence of large spherical globules in crushed sciatic *** findings suggest that guinea pigs could be used as an alternative animal model for nerve regeneration studies and might be preferred over rats due to their cooperative nature while recording different parameters.

关键词： nerve regeneration Guinea pigs animal model sciatic nerve injury foot print length neuropilin histopathology neural regeneration

Large unsaturated room temperature negative magnetoresistance in graphene foam composite for wearable and flexible magnetoelectronics

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Nano Research 2019年第1期12卷 101-107页

作者： Rizwan Ur Rehman Sagar Massimiliano Galluzzi Alberto Garcia-Penas Masroor Ahmad bhat Min Zhang Florian J.Stadler College of Materials Science and Engineering Shenzhen Key Laboratory of Polymer Science and TechnologyGuangdong Research Center for Interfacial Engineering of Functional MaterialsNanshan District Key Lab for Biopolymers and Safety EvaluationShenzhen UniversityShenzhen 518060China Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province College of Optoelectronic EngineeringShenzhen UniversityShenzhen 518060China Graduate School at Shenzhen Tsinghua UniversityShenzhen 518055China Shenzhen Key Laboratory of Nanobiomechanics Shenzhen Institutes of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China

Room temperature positive magnetoresistance(PMR)in graphene is a conventional phenomenon but we observed large negative magnetoresistance(NMR)in graphene foam(GF)/polydimethylsiloxane(GF/PDMS)at room-mperature for the first *** largest NMR^35%was detected at 250 K,while PMR is observed below 200 ***,PMR at all temperatures is observed in regular GF specimens,hence,NMR is the result of the infiltration with the electrically insulating *** interference and wavefunction shrinkage model has been employed to understand the transport mechanism in GF/PDMS.A critical temperature^224 Kfor switching between NMR and PMR is observed at the crystallization-mperature of PDMS,suggesti ng a cha nge in polymer chai n con formation may be a major reason leading to NMR in GF/PDMS specimens thus role of mechanical properties of PDMS in NMR cannot be ignored and observed locally via specially;resolved atomic force *** addition,storage modulus and heat flow study shows similar transition temperature(~200 K)of NMR to PMR and provide an evidence of mechanical stable *** is known,large,tunable,and unsaturated NMR at room temperature is very useful for future facile practical shapeable magnetoelectronic devices.

关键词： chemical vapor deposition graphene foam negative magnetoresistanee

Systematic study of odd-mass^151-161Pm and^154,156Pm isotopes using projected shell model

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Chinese Physics C 2020年第9期44卷 142-153页

作者： Veerta Rani Preeti Verma Suram Singh Manvi Rajput Arun Bharti G.H.bhat J.A.Sheikh Department of Physics and Astronomical Sciences Central University of JammuSambaJ&K181143India Department of Physics University of JammuJammu180001India Department of Physic S.P.CollegeCluster University Srinagar190001India Cluster University Srinagar J&K190001India

Inspired by the availability of recent experimental as well as theoretical data on the energy levels of odd-mass^151-161Pm and odd-odd^154,156Pm,we applied the theoretical framework of the projected shell model to further understand the nuclear structure of these *** calculations closely reproduced the experimental data reported for the yrast bands of these isotopes by assuming an axial(prolate)deformation of^*** properties along the yrast line,such as transition energies and transition probabilities,have also been *** diagrams are plotted to understand their intrinsic multi-quasiparticle structure,which turn out to be dominated by 1-quasiparticle bands for the odd-mass Pm isotopes and 2-quasiparticle bands for the doubly-odd Pm isotopes under *** present study not only confirms the recently reported experimental/theoretical data,but also extends the already available information on the energy levels and adds new information regarding the reduced transition probabilities.

关键词： projected shell model yrast spectra band diagram transition energies reduced transition probabilities

PGE and isotopic characteristics of Shergol and Suru Valley Ophiolites,Western Ladakh:Implications for supra-subduction tectonics along Indus Suture Zone

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Geoscience Frontiers 2021年第3期12卷 473-488页

作者： Irfan Maqbool bhat Talat Ahmad D.V.Subba Rao Srinivasan Balakrishnan N.V.Chalapathi Rao Department of Earth Sciences University of KashmirSrinagar 190006India Vice Chancellors Office University of KashmirSrinagar 190006India Geochemistry Division CSIR-National Geophysical Research Institute(NGRI)Hyderabad 500007India Department of Earth Sciences Pondicherry UniversityPuducherry 605014India Centre of Advanced Study in Geology Institute of ScienceBanaras Hindu UniversityVaranasi 221005India

Present study reports the PGE-geochemistry of mantle peridotites and Nd-isotope geochemistry of arc related mafic rocks from the Indus Suture Zone(ISZ),western *** total PGE concentration of the Shergol and Suru Valley peridotites(∑PGE=96-180 ppb)is much higher than that of the primitive mantle and global ophiolitic mantle *** studied peridotites show concave upward PGE-distribution patterns with higher palladium-group PGE/Iridium-group PGE ratios(i.e.,0.8-2.9)suggesting that the partial melting is not the sole factor responsible for the evolution of these *** observed PGE-distribution patterns are distinct from residual/refractory mantle peridotites,which have concave downward or flat PGE-distribution *** enrichment of palladium-group PGE as well as other whole-rock incompatible elements(e.g.,LILE and LREE)and higher Pd/Ir ratio(1.1-5.9)reflects that these peridotites have experienced fluid/melt interaction in a supra-subduction zone(SSZ)tectonic ***,the Shergol mafic intrusives and Dras mafic volcanics,associated with the studied peridotites,have high^(143)Nd/^(144)Nd ratios(i.e.,0.512908-0.513078 and 0.512901-0.512977,respectively)and positiveε_(Nd)(t)(calculated for t=140 Ma)values(i.e.,+5.3 to+8.6 and+5.1 to+6.6,respectively),indicating derivation from depleted mantle sources within an intra-oceanic arc setting,similar to Spongtang and Nidar ophiolites from other parts of Ladakh *** transition from SSZ-type Shergol and Suru Valley peridotites to Early Cretaceous tholeiitic Shergol mafic intrusives followed by tholeiitic to calc-alkaline Dras mafic volcanics within the Neo-Tethys Ocean exhibit characteristics of subduction initiation mechanism analogous to the Izu-Bonin-Mariana arc system within western Pacific.

关键词： PGE Nd-isotope Mantle peridotites Ophiolites Ladakh Neo-Tethys Ocean

Optimized Mn and Bi co-doping in SnTe based thermoelectric material:A case of band engineering and density of states tuning

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Journal of Materials Science & Technology 2021年第26期85卷 76-86页

作者： Samuel Kimani Kihoi Joseph Ngugi Kahiu Hyunji Kim U.Sandhya Shenoy D.Krishna bhat Seonghoon Yi Ho Seong Lee School of Materials Science and Engineering Kyungpook National University80 Daehak-roBuk-guDaegu 41566Republic of Korea Department of Hydrogen and Renewable Energy Kyungpook National University80 Daehak-roBuk-guDaegu 41566Republic of Korea Department of Chemistry College of Engineering and TechnologySrinivas UniversityMukka574146 MangaloreKarnatakaIndia Department of Chemistry National Institute of Technology KarnatakaSurathkalSrinivasnagar575025 MangaloreKarnatakaIndia

Tin telluride(SnTe)overwhelmingly continues to be studied owing to its promising thermoelectric properties,tunable electronic structure,and its potential as an alternate to toxic lead telluride(PbTe)based *** this research,we engineer the electronic properties of SnTe by co-doping Mn and Bi below their individual solubility *** First principles density functio nal theory studies reveal that both Bi and Mn introduce resonance states,thereby increasing the density of states near the Fermi level leading to enhanced Seebeck *** unique combination of using two resonant dopants to introduce flatter bands is effective in achieving higher performance at lower tempe ratures manifesting into a large Seebeck value of~91μV/K at room temperature in the present *** elements optimally co-doped results in a very high power factor value of~24.3μW/cmK^(2) at 773 K when compared to other high performance SnTe based materials.A zT of~0.93 at 773 K is achieved by tuning the proportion of the co-dopants Mn and Bi in *** hardness value of pristine SnTe was also seen to increase after *** a result,synergistic optimized doping proves to be a suitable means for obtaining thermoelectric materials of superior characteristics without the need for heavy doping.

关键词： SnTe Thermoelectric Electronic structure engineering Solubility Thermal conductivity

Forest structure, diversity and regeneration in unburnt and burnt Anogeissus latifolia forests in Garhwal Himalayas

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Forestry Studies in China 2012年第4期14卷 268-275页

作者： Munesh KUMAR Jahangeer A. bhat G. S. RAJWAR Department of Forestry and Natural Resources HNB Garhwal University Department of Botany Government Post Graduate College

The present study was carried out at two different gradients of unbumt and burnt Anogeissus latifolia forest sites in the Garhwal region, India. At each gradient, the unburnt and burnt forest sites were further categorized into three different elevations, i.e., lower （700 m）, middle （850 m） and upper （1000 m）. At each elevation, the density of trees, saplings and seedlings was higher at the unburnt sites except for trees at the upper elevation which was higher at the burnt sites. The total basal area of each layer of for- est was also higher at the unburnt sites. The study revealed that the lower number of saplings and seedlings at the burnt forest sites might be due to the effect of fire. Most trees in the lower dbh classes were affected by forest fire at the burnt sites which reduced the total density and total basal area of the trees compared to the unburnt sites. The diversity of trees increased with increasing elevation. However, the diversity of saplings and seedlings reduced with increasing elevation.

关键词： Anogeissus latifolia unburnt and burnt forest elevational gradient diversity regeneration

Characterization of Mixed Neodymium Lanthanum Heptamolybdate Crystals Grown by Gel Encapsulation Technique

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Journal of Materials Science & Technology 1995年第1期11卷 41-45页

作者： Sushma bhat and P.N.Kotru(Dept. of Physics, University of Jammu, Jammu, India) UNIV JAMMU DEPT PHYS JAMMU INDIA

Crystals of mixed NdLa heptamolybdates (max. size0.75×0.75×0.75 mm3) grown by silica gel technique were characterized using EDAX, IR, optical and scanning electron micrscopies.X-ray as well as electrn diffraction. The composition of the crystals was determined as (Nd1/2 La1/2 )2 Mo7O24·*** crystals exhibit varied morpholgies including square and octagonal platelets, cuboids, multifaceted crystal in coalesced and aggregated forms and *** XRD results indicate crystallinity of the grown material. Electron diffraction results suggest thermal instability of the material. IR results show the presence of peaks due to water and metal-oxygen bonds

关键词： Figure La