检索结果-南通市图书馆

Sodium glucose cotransporter 2 inhibitors in the management of heart failure:Veni,Vidi,and Vici

World Journal of Cardiology 2024年第10期16卷 550-563页

作者： Monika bhandari Akshyaya Pradhan Pravesh Vishwakarma Abhishek Singh Rishi Sethi Department of Cardiology King Georg’s Medical UniversityLucknow 226003Uttar PradeshIndia

Heart failure(HF)is a chronic disease associated with high morbidity and mortality ***-angiotensin-aldosterone system blockers(including angiotensin receptor/neprilysin inhibitors),beta-blockers,and mineralocorticoid receptor blockers remain the mainstay of pharmacotherapy for HF with reduced ejection fraction(HFrEF).However,despite the use of guideline-directed medical therapy,the mortality from HFrEF remains *** with preserved ejection fraction(HFpEF)comprises approximately half of the total incident HF cases;however,unlike HFrEF,there are no proven therapies for this *** glucose cotransporter-2 inhibitors(SGLT-2is)represent a new class of pharmacological agents approved for diabetes mellitus(DM)that inhibit SGLT-2 receptors in the kidney.A serendipitous finding from seminal trials of SGLT-2is in DM was the significant improvement in renal and cardiovascular(CV)*** importantly,the improvement in HF hospitalization(HHF)in the CV outcomes trials of SGLT-2is was *** mechanisms have been proposed for the pleiotropic effects of SGLT-2is beyond their glycemic ***,as patients with HF were not included in any of these trials,it can be considered as a primary ***,two landmark studies of SGLT-2is in patients with HFrEF,namely,an empagliflozin outcome trial in patients with chronic HF and a reduced ejection fraction(EMPEROR-Reduced)and dapagliflozin and prevention of adverse outcomes in HF(DAPA-HF),demonstrated significant improvement in HHF and CV mortality regardless of the presence of *** impressive results pitchforked these drugs as class I indications in patients with HFrEF across major ***,empagliflozin outcome trial in patients with chronic HF with preserved ejection fraction(EMPEROR-Preserved)and dapagliflozin evaluation to improve the lives of patients with preserved ejection fraction HF(DELIVER)trials successively confirmed that SGLT-2is also benefit patients w

关键词： Heart failure with preserved ejection fraction Gliflozins Diuresis Natriuresis N terminal-pro brain natriuretic peptide Heart failure hospitalization

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Numerical modelling of post-failure behaviors of coal specimens

引用

Journal of Rock Mechanics and Geotechnical Engineering 2024年第2期16卷 514-531页

作者： Ajeet Yadav Bhaskara Behera Gauri Shankar prasad Singh Sanjay Kumar Sharma Department of Mining Engineering Indian Institute of Technology(Banaras Hindu University)VaranasiUttar Pradesh221005India

A modelling approach consisting of best-fit relations to estimate the post-yield strength parameters is presented for simulating post-peak behavior beyond the point of residual strength of coal pillars having different w/h *** model was developed based on back-analysis of the complete stress-strain behavior of specimens belonging to six different Indian coal seams with different w/h ratios of 0.5 *** was found that the simultaneous degradation of the cohesion and friction angle of the Mohr-Coulomb rock material characterizes the post-peak strength behavior of the *** resulting expressions are simplistic as they require parameters that can be easily determined using uniaxial and triaxial compression ***,the developed model was validated by simulating the triaxial tests of coal specimens with different sizes under varying confining stresses and comparing its findings with the published test *** study showed that its implementation in the numerical model could reproduce laboratory-observed mechanical response,deformation behavior,and failure mechanism very closely.

关键词： Strain softening Dilatancy Interface Shape effect Residual strength

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Enhancing corrosion resistance of plasma electrolytic oxidation coatings on AM50 Mg alloy by inhibitor containing Ba(NO_(3))_(2) solutions

引用

International Journal of Minerals,Metallurgy and Materials 2024年第9期31卷 2048-2061页

作者： Jirui Ma Xiaopeng Lu Santosh prasad Sah Qianqian Chen You Zhang Fuhui Wang Corrosion and Protection Center Northeastern UniversityShenyang110819China Faculty of Engineering Hokkaido UniversityHokkaido 060-8628Japan College of New Materials and Chemical Engineering Beijing Institute of Petrochemical TechnologyBeijing 102617China

To enhance the long-term corrosion resistance of the plasma electrolytic oxidation(PEO)coating on the magnesium(Mg)alloy,an inorganic salt combined with corrosion inhibitors was used for posttreatment of the *** this study,the corrosion performance of PEO-coated AM50 Mg was significantly improved by loading sodium lauryl sulfonate(SDS)and sodium dodecyl benzene sulf-onate into Ba(NO_(3))_(2) post-sealing *** electron microscopy,X-ray photoelectron spectroscopy,X-ray diffraction,Fourier transform infrared spectrometer,and ultraviolet-visible analyses showed that the inhibitors enhanced the incorporation of BaO_(2) into PEO *** impedance showed that post-sealing in Ba(NO_(3))_(2)/SDS treatment enhanced corrosion resistance by three orders of *** total impedance value remained at 926Ω·cm^(2)after immersing in a 0.5wt%NaCl solution for 768 h.A salt spray test for 40 days did not show any obvious region of corrosion,proving excellent post-sealing by Ba(NO_(3))_(2)/SDS *** corrosion resistance of the coating was enhanced through the synergistic effect of BaO2 pore sealing and SDS adsorption.

关键词： Mg plasma electrolytic oxidation posttreatment corrosion resistance

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Exercise and exerkine upregulation:Brain-derived neurotrophic factor as a potential non-pharmacological therapeutic strategy for Parkinson’s disease

引用

BIOCELL 2024年第5期48卷 693-706页

作者： VIRAAJ VISHNU prasad JENNIFER SALLY SAMSON VENKATACHALAM DEEPA PARVATHI Department of Biomedical Sciences Sri Ramachandra Institute of Higher Education and ResearchChennai600116India

Physical activity and exercise have several beneficial roles in enhancing both physiological and psychological well-being of an *** addition to aiding the regulation of aerobic and anaerobic metabolism,exercise can stimulate the synthesis of exerkine hormones in the circulatory *** several exerkines that have been investigated for their therapeutic potential,Brain-derived neurotrophic factor(BDNF)is considered the most promising candidate,especially in the management of neurodegenerative *** to the ability of physical activity to enhance BDNF synthesis,several experimental studies conducted so far have validated this hypothesis and produced satisfactory results at the pre-clinical *** review highlights some of the recent animal model studies that have evaluated the efficiency of exercise in enhancing BDNF synthesis and promoting neuroprotective ***,this review focuses on understanding the therapeutic benefits of exercise-induced exerkine synthesis as a non-pharmacological strategy in Parkinson’s disease(PD).Regarding physical activity and exerkine induction,the neuromuscular electrical stimulation(NMES)strategy could be considered as an alternate treatment modality for patients affected with PD.

关键词： Exercise therapy Dopaminergic neurons Parkinson’s disease Brain-derived neurotrophic factor Electrical stimulation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Poplar Plantation as an Agroforestry Approach:Economic Benefits and Its Role in Carbon Sequestration in North India

引用

Journal of Resources and Ecology 2024年第4期15卷 880-888页

作者： Rajeev JOSHI bharat SHARMA Hukum SINGH Nabin DHAKAL Santosh AYER Tek MARASENI College of Natural Resource Management Faculty of ForestryAgriculture and Forestry UniversityUdayapurKatari 56310Nepal Sustainable Initiatives for the Community(SIFC) Kathmandu 44600Nepal Forest Research Institute PO New ForestDehradun 248006India Institute for Life Sciences and the Environment University of Southern QueenslandToowoombaQLD 4350Australia

Poplar has gained popularity among farmers of Punjab,Haryana,Western Uttar Pradesh,and the foothills of Uttarakhand and Himachal Pradesh due to their fast growth rate and suitability for industrial uses such as pulp and timber *** poplar trees into agroforestry systems optimizes land resources and economic gains,as successful techniques have been developed to coordinate crop timing and arrangements *** poplar trees with agricultural crops provides additional income streams for farmers and contributes to soil conservation,biodiversity enhancement,and other environmental *** in these regions typically employ effective spacing of 5 m×4 m for block plantation and 1 m×3 m for row *** the present study,a systematic literature review encompassing 137 English-language journal articles was conducted to assess the economic benefits of Poplar using discounted cash flow(DCF)analysis,considering short-rotation poplar(SRC)and very short-rotation poplar(vSRC)plantations alongside annual *** findings revealed that increasing canopy density led to a decline in crop yields by 37%,70%,and 99% at canopy densities of 30%,60%,and 90%,respectively,from early spring to ***-benefit analysis in Saharanpur district,India,indicated average annual net returns of USD 346.36 for Poplar-based agrisilviculture,while monoculture yielded USD 140.73 per ***,economic analysis in Yamunanagar and Haridwar districts showed benefit-cost ratios ranging from 2.35 to ***,Poplar block and boundary plantations were found to sequester significantly more carbon in long-lived biomass,serving as substitutes for fossil fuels(5.45 and 1.84 t ha-1 yr-1)in poplar-based systems with block and boundary *** study suggested expanding spacing between tree rows may mitigate resource competition between plantations and *** study inferred that Poplar-based agroforestry may play a crucial role in climate mit

关键词： agroforestry poplar economic viability carbon sequestration India

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Patterns,Causes and Perceptions of Human-Large Carnivore Conflict in the Chitwan National Park,Nepal

引用

Journal of Resources and Ecology 2024年第4期15卷 838-849页

作者： Parwati TIWARI Bishnu prasad BHATTARAI Jagan Nath ADHIKARI Binod BHATTARAI Central Department of Zoology Institute of Science and TechnologyTribhuvan UniversityKathmandu 44600Nepal Department of Zoology Birendra Multiple CampusTribhuvan UniversityChitwan 44200Nepal Nepal Zoological Society Kathmandu 44600Nepal

One of the major management problems in and around protected areas is the intensifying conflict between local people and wildlife,especially large *** depredation and human fatalities caused by attacks of carnivores are found to be serious obstacles in conflict *** study aims to explore the patterns,costs,causes and perceptions of human large carnivore conflict in the Nawalpur area of Chitwan National *** patterns of livestock loss and human casualties due to large carnivores(Panthera tigris and Panthera pardus)were analysed using the secondary data reported to Chitwan National Park from 2001 to *** understand the people’s perception towards carnivores and wildlife conservation,150 victim respondents were asked,with one household selected from each *** 19-year study period,a total of 521 incidents caused by large carnivores were reported,which included 33 human casualties and 488 livestock *** was responsible for the maximum conflict incidents in *** total relief provided for human deaths and injuries was US$17524.41,whereas US$13702.18 was used to compensate for livestock depredation in the Nawalpur area by authorities of the Chitwan National *** than 64%of the respondents liked the presence of carnivores in their area and had a positive attitude toward the conservation of large carnivores,even though the carnivores were responsible for livestock depredation and human injury and ***’s satisfaction with the relief scheme provided by the government depended on ethnicity,gender,age class,occupation,education,insurance,and livestock ownership,but they believed the scheme was not ***,an effective relief scheme and awareness about the process of relief funding should be conducted in conflict *** awareness programs for local communities about large carnivores,their behavior,and preparing predator-proof corrals would be helpful in minimizing conflict in the study a

关键词： depredation human wildlife conflict leopard tiger relief fund

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Impact factors and pathways of halonitromethanes formation from aspartic acid during LED-UV_(265)/chlorine disinfection

引用

Frontiers of Environmental Science & Engineering 2024年第1期18卷 129-144页

作者： Liangwen Zhu Tao Wang Qian Tang Qing Wang Lin Deng Jun Hu Chaoqun Tan Rajendra prasad Singh Key Laboratory of Concrete and Prestressed Concrete Structures of Ministry of Education School of Civil EngineeringSoutheast UniversityNanjing 211189China College of Environment Zhejiang University of TechnologyHangzhou 310014China

Light emitting diode (LED-UV)/chlorine disinfection can replace UV/chlorine disinfection in wastewater treatment plants and water supply plants. Halonitromethanes (HNMs) are a class of novel nitrogenous disinfection by-products, which are characterized by higher cytotoxicity and genotoxicity than regulated disinfection by-products. Herein, the impact factors and pathways of HNMs formation from aspartic acid (ASP) were investigated during LED-UV_(265)/chlorine disinfection. The results showed that three types of chlorinated-HNMs (Cl-HNMs) were found during LED-UV265/chlorine disinfection, and their concentrations increased first and then declined as the reaction progressed. Cl-HNMs yields increased with increasing LED-UV_(265) intensity, free chlorine dosage, and ASP concentration, which declined with increasing pH (6.0–8.0). Meantime, the important impact of the coexisting ions contained in water matrices on HNMs formation from ASP was observed during LED-UV_(265)/chlorine disinfection. It was found that copper ions (Cu^(2+)) promoted Cl-HNMs formation. Furthermore, when bromide (Br–) appeared during LED-UV265/chlorine disinfection, nine types of HNMs were detected simultaneously. Moreover, Br– not only converted Cl-HNMs toward brominated (chlorinated)-HNMs and brominated-HNMs but also showed a marked effect on HNMs concentrations and species. Subsequently, the possible pathways of HNMs formation from ASP were proposed during LED-UV_(265)/chlorine disinfection. At last, it was proved that the formation trends of HNMs obtained in the real waters were similar to those in simulated waters. This work elaborated on the influence factors and pathways of HNMs formation, which is conducive to controlling the HNMs produced during LED-UV_(265)/chlorine disinfection.

关键词： LED-UV265 chlorine HNMs Aspartic acid Bromide Copper ions

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Preparedness,knowledge,and perception of nursing students about climate change and its impact on human health in India

引用

Regional Sustainability 2024年第1期5卷 107-118页

作者： Ramya Kundayi RAVI Priya BABY Nidhin ELIAS Jisa George THOMAS Kathyayani Bidadi VEERABHADRAIAH bharat PAREEK College of Nursing Medical and Health Sciences UniversityRas Al Khaimah11172United Arab Emirates College of Nursing National Institute of Mental Health and Neuro sciencesBangalore560011India College of Nursing Amrita Institute of Medical SciencesKochi682041India College of Nursing All India Institute of Medical SciencesBhopal462020India Saraswati Professional and Higher Education College of Nursing Mohali140413India

Higher education plays an important role in all aspects of *** climate change and sustainability into the curriculum is important to prepare future health-care professionals for climate change and sustainability actions to build resilient health *** this study,we evaluated the preparedness,knowledge,and perception regarding climate change and its impact on human health among Indian nursing students.A quantitative descriptive survey was conducted among 644 undergraduate nursing students studying in three institutes in the southern,northern,and western parts of *** used a structured online questionnaire with established validity and reliability to collect *** data were analyzed using Statistical Package for the Social Sciences version 26 *** results showed that more than half of the students reported experiencing excessive increase(362;56.2%)and decrease(374;58.1%)in temperature in recent *** more than three quarters of the students(494;76.7%)accepted the general truth that climate change is mainly caused by human activities,only less than half of the students(309;48.0%)perceived the impact of climate change to be *** quarters of the students(483;75.0%)had a high level of knowledge regarding climate *** students who had a high level of knowledge about climate change exerted a high perceived impact of climate change(χ^(2)=75.47;P<0.01).More than half of the students(50.9%)felt that they needed information about climate change to be included in the nursing curriculum,and only one sixth of the students(16.1%)were highly confident about engaging in climate change-related conversation with *** of the students who participated in the study had basic knowledge about climate change and its impact on human ***,there is an observed gap between knowledge and their preparedness and confidence to engage in climate change ***,we propose to strengthen the nursing curriculum by integra

关键词： Climate change Curriculum Nursing students Human health India

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Design of a Multi-Stage Ensemble Model for Thyroid Prediction Using Learning Approaches

引用

Intelligent Automation & Soft Computing 2024年第1期39卷 1-13页

作者： M.L.Maruthi prasad R.Santhosh Department of Computer Science and Engineering Faculty of EngineeringKarpagam Academy of Higher EducationCoimbatoreTamil NaduIndia

This research concentrates to model an efficient thyroid prediction approach,which is considered a baseline for significant problems faced by the women *** major research problem is the lack of automated model to attain earlier *** existing model fails to give better prediction ***,a novel clinical decision support system is framed to make the proper decision during a time of *** stages are followed in the proposed framework,which plays a substantial role in thyroid *** steps include i)data acquisition,ii)outlier prediction,and iii)multi-stage weight-based ensemble learning process(MS-WEL).The weighted analysis of the base classifier and other classifier models helps bridge the gap encountered in one single classifier *** classifiers aremerged to handle the issues identified in others and intend to enhance the prediction *** proposed model provides superior outcomes and gives good quality prediction *** simulation is done in the MATLAB 2020a environment and establishes a better trade-off than various existing *** model gives a prediction accuracy of 97.28%accuracy compared to other models and shows a better trade than others.

关键词： Thyroid machine learning pre-processing classification prediction rate

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Comprehensive Overview and Analytical Study on Automatic Bird Repellent Laser System for Crop Protection

引用

Journal of Harbin Institute of Technology(New Series) 2024年第1期31卷 38-53页

作者： Sireesha Abotula Srinivas Gorla prasad Reddy PVGD Mohankrishna S Department of Computer Science and Engineering GITAM Deemed to be UniversityVisakhapatnam 530045India Department of Information Technology Andhra UniversityVisakhapatnam 530003India Department of Computer Science and Systems Engineering Andhra UniversityVisakhapatnam 530003India

Birds are a huge hazard to agriculture all around the world,causing harm to profitable field *** use a variety of techniques to keep them away,including visual,auditory,tactile,and olfactory deterrents. This study presents a comprehensive overview of current bird repellant approaches used in agricultural contexts,as well as potential new ways. The bird repellent techniques include Internet of Things technology,Deep Learning,Convolutional Neural Network,Unmanned Aerial Vehicles,Wireless Sensor Networks and Laser biotechnology. This study’s goal is to find and review about previous approach towards repellent of birds in the crop fields using various technologies.

关键词： Bird repellent crop protection IoT UAV Deep Learning

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：