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Morbidity Profile and Causes of Mortality in Type 2 Diabetes Patients: Data from a Tertiary Teaching Hospital from Eastern India

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Journal of Diabetes Mellitus 2017年第3期7卷 195-211页

作者： Soumya Ranjan Behera Manoranjan Behera Sidhartha Das bhabani prasad panda Saroj Kumar Tripathy Purna Chandra Dash Department of Medicine VSS Institute of Medical Sciences and Research Burla Sambalpur Odisha India PG Department of Medicine Faculty of Medicine Sriram Chandra Bhanja Medical College Cuttack Odisha India PG Department of Medicine Sriram Chandra Bhanja Medical College Cuttack Odisha India

Background: Data regarding the prevalence of morbidity and mortality in patients of Type 2 Diabetes Mellitus (T2DM) is scanty in India. Objectives: To determine the prevalence of micro and macro vascular complications, acute metabolic complications, infections, Non Alcoholic Fatty Liver Disease (NAFLD) and cause of mortality in T2DM patients admitted to a tertiary care teaching hospital in Eastern India. Material and Methods: This was a hospital-based prospective study evaluating 150 T2DM patients admitted to a tertiary care institution in Eastern India. Diagnosis of micro and macro vascular complications, infections and NAFLD was made using standard protocols. In case of death, the most probable cause was noted. Results: Out of 150 patients, 14.7% of patients were newly diagnosed T2DM and out of them 41% of patients had vascular complications and 54.5% had infections. Of the total patients, 56% had nephropathy, 20% neuropathy, 17.3% retinopathy, 31.3% CVD, 11.3% CAD, 4.6% acute metabolic complications, 44% infections and 16.6% had NAFLD respectively. Macrovascular events occured earlier than microvascular complications. Multiple logistic regression analysis showed strong association of age, duration of diabetes, serum cholesterol, triglyceride, LDL-C with retinopathy (Regression coefficient β: -0.1086807, 0.4127152, -0.0513393, 0.0146429, 0.0587475;p < 0.05, < 0.001, < 0.05, < 0.05, < 0.05 respectively), while only duration of diabetes was strongly associated with nephropathy and neuropathy (Regression coefficient β: 0.2538751, 0.2261636;p < 0.001 for each). Increasing age was associated with CAD (Regression coefficient β: 0.055392;p β: 0.0055014;p 18.6% patients died due to diabetes related complications. Cardiovascular (CV)-related deaths (CVD+CAD) were most common cause (51.5%: CVD 36.4%, CAD 15.1%) to be followed by infections (27.3%) and then chronic kidney disease (12.1%). Conclusions: This study highlights the high prevalence of vascular complications and in

关键词： Type 2 Diabetes Mellitus Vascular Complications Infections NAFLD Mortality

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Comparison of Different Approaches of Finding the Positive Definite Metric in Pseudo-Hermitian Theories

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Communications in Theoretical Physics 2013年第5期59卷 533-539页

作者： Ananya Ghatak bhabani prasad Mandal Department of Physics Banaras Hindu University

To develop a unitary quantum theory with probabilistic description for pseudo-Hermitian systems one needs to consider the theories in a different Hilbert space endowed with a positive definite metric operator. There are different approaches to find such metric operators. We compare the different approaches of calculating positive definite metric operators in pseudo-Hermitian theories with the help of several explicit examples in non-relativistic as well as in relativistic situations. Exceptional points and spontaneous symmetry breaking are also discussed in these models.

关键词： pseudo-Hermitian quantum theory positive definite metric operator relativistic non-Hermitian system P T symmetry quantum mechanics modified Hilbert space

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Complex Classical Mechanics of a QES Potential

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Communications in Theoretical Physics 2015年第10期64卷 425-432页

作者： bhabani prasad Mandal Sushant S.Mahajan Department of Physics Banaras Hindu University Department of Physics Indian Institute of Technology Banaras Hindu University

We study a combined parity(P) and time reversal(T) invariant non-Hermitian quasi-exactly solvable(QES) potential, which exhibits PT phase transition, in the complex plane classically to demonstrate different quantum effects. The particle with real energy makes closed orbits around one of the periodic wells of the complex potential depending on the initial condition. However interestingly the particle escapes to an open orbits even with real energy if it is placed beyond a certain distance from the center of the well. On the other hand when the particle energy is complex the trajectory is open and the particle tunnels back and forth between two wells which are separated by a classically forbidden path. The tunneling time is calculated for different pair of wells and is shown to vary inversely with the imaginary component of energy. Our study reveals that spontaneous PT symmetry breaking does not affect the qualitative features of the particle trajectories in the analogous complex classical model.

关键词： PT symmetric complex systems quasi-exactly solvabl

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Non-invasive cuffless blood pressure and heart rate monitoring using impedance cardiography

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Intelligent Medicine 2022年第4期2卷 199-208页

作者： Sudipta Ghosh bhabani prasad Chattopadhyay Ram Mohan Roy Jayanta Mukherjee Manjunatha Mahadevappa Department of Computer Science&Engineering Indian Institute of Technology KharagpurKharagpurWest Bengal 721302India School of Medical Science&Technology Indian Institute of Technology KharagpurKharagpurWest Bengal 721302India Department of Cardiology Medical College&HospitalKolkataWest Bengal 700073India

Background Continuous blood pressure(BP)monitoring provides additional information about how changes in BP may correlate with daily activities and sleep *** from the American Heart Association and American College of Cardiology strongly suggest confirming a diagnosis of hypertension with continuous BP ***-invasive and non-intrusive detection of haemodynamic parameters is emerging as a norm,based on self-monitoring wearable medical *** have carried out several studies using non-invasive and continuous BP measurements as an alternative to conventional cuff-based *** this work,we proposed a novel method for cuffless estimation of BP using impedance cardiography(ICG).Methods We conducted a single-centre,cross-sectional study of 104 subjects(of whom 30 were categorized as controls and the remaining 74 as the disease group)at the Medical College and Hospital,*** disease group consisted of patients with confirmed coronary artery disease,while the individuals in the control group were deemed to be *** subjects underwent electrocardiogram recording by on-duty doctors in order to determine their health status.A custom-made device based on the principle of impedance plethysmography was designed to record impedance changes due to subjects’peripheral blood *** device was used to record ICG *** this study,we developed a novel auto-adaptive algorithm based on ICG signals for non-invasive,cuffless,continuous monitoring of BP and heart *** mathematical models were developed for all the estimated parameters(BP and heart rate)for both the study groups(control and disease).The developed models were auto-adaptive and did not require subject-specific *** indicators including,𝑟2,error percentage,standard deviation,and mean difference were used to quantify the performance of the *** The ICG signal recorded by the device was used to extract features and compute t

关键词： Impedance cardiography Augmentation index Systolic pressure Diastolic pressure Heart rate

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